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01-03-2007 | Original Paper

Studying the Emergence of Autism Spectrum Disorders in High-risk Infants: Methodological and Practical Issues

Auteurs: Lonnie Zwaigenbaum, Audrey Thurm, Wendy Stone, Grace Baranek, Susan Bryson, Jana Iverson, Alice Kau, Ami Klin, Cathy Lord, Rebecca Landa, Sally Rogers, Marian Sigman

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2007

Abstract

Detecting early signs of autism is essential for timely diagnosis and initiation of effective interventions. Several research groups have initiated prospective studies of high-risk populations including infant siblings, to systematically collect data on early signs within a longitudinal design. Despite the potential advantages of prospective studies of young children at high-risk for autism, there are also significant methodological, ethical and practical challenges. This paper outlines several of these challenges, including those related to sampling (e.g., defining appropriate comparison groups), measurement and clinical implications (e.g., addressing the needs of infants suspected of having early signs). We suggest possible design and implementation strategies to address these various challenges, based on current research efforts in the field and previous studies involving high-risk populations.

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Titel: Studying the Emergence of Autism Spectrum Disorders in High-risk Infants: Methodological and Practical Issues
Auteurs: Lonnie Zwaigenbaum
Audrey Thurm
Wendy Stone
Grace Baranek
Susan Bryson
Jana Iverson
Alice Kau
Ami Klin
Cathy Lord
Rebecca Landa
Sally Rogers
Marian Sigman
Publicatiedatum: 01-03-2007
Uitgeverij: Kluwer Academic Publishers-Plenum Publishers
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 3/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0179-x

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