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Gepubliceerd in:

01-04-2015

Stress, depression and medication nonadherence in diabetes: test of the exacerbating and buffering effects of family support

Auteurs: Lindsay Satterwhite Mayberry, Leonard E. Egede, Julie A. Wagner, Chandra Y. Osborn

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 2/2015

Abstract

Stressors and depressive symptoms have been associated with medication nonadherence among adults with type 2 diabetes (T2DM). We tested whether these associations were exacerbated by obstructive family behaviors or buffered by supportive family behaviors in a sample of 192 adults with T2DM and low socioeconomic status using unadjusted and adjusted regression models. We found support for the exacerbating hypothesis. Stressors and nonadherence were only associated at higher levels of obstructive family behaviors (interaction AOR = 1.12, p = .002). Similarly, depressive symptoms and nonadherence were only associated at higher levels of obstructive family behaviors (interaction AOR = 3.31, p = .002). When participants reported few obstructive family behaviors, neither stressors nor depressive symptoms were associated with nonadherence. We did not find support for the buffering hypothesis; stressors and depressive symptoms were associated with nonadherence regardless of supportive family behaviors. Nonadherent patients experiencing stressors and/or major depressive symptoms may benefit from interventions that reduce obstructive family behaviors.

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Anderson, R. J., Freedland, K. E., Clouse, R. E., & Lustman, P. J. (2001). The prevalence of comorbid depression in adults with diabetes: A meta-analysis. Diabetes Care, 24, 1069–1078.CrossRefPubMed

Baek, R. N., Tanenbaum, M. L., & Gonzalez, J. S. (2014). Diabetes burden and diabetes distress: The buffering effect of social support. Annals of Behavioral Medicine, 48, 145–155.

Beekman, A. T., Penninx, B. W., Deeg, D. J., Ormel, J., Braam, A. W., & van Tilburg, W. (1997). Depression and physical health in later life: Results from the Longitudinal Aging Study Amsterdam (LASA). Journal of Affective Disorders, 46, 219–231.CrossRefPubMed

Behling, O., & Law, K. S. (Eds.). (2000). Translating questionnaires and other research instruments: Problems and solutions (Vol. 133). Thousand Oaks: Sage.

Billimek, J., & Sorkin, D. H. (2012a). Food insecurity, processes of care, and self-reported medication underuse in patients with type 2 diabetes: Results from the California Health Interview Survey. Health Services Research, 47, 2159–2168.CrossRefPubMedCentralPubMed

Billimek, J., & Sorkin, D. H. (2012b). Self-reported neighborhood safety and nonadherence to treatment regimens among patients with type 2 diabetes. Journal of General Internal Medicine, 27, 292–296.CrossRefPubMedCentralPubMed

Carter-Edwards, L., Skelly, A. H., Cagle, C. S., & Appel, S. J. (2004). “They care but don’t understand”: Family support of African American women with type 2 diabetes. Diabetes Educator, 30, 493–501.CrossRefPubMed

Choo, P. W., Rand, C. S., Inui, T. S., Lee, M. L., Cain, E., Cordeiro-Breault, M., et al. (1999). Validation of patient reports, automated pharmacy records, and pill counts with electronic monitoring of adherence to antihypertensive therapy. Medical Care, 37, 846–857.CrossRefPubMed

Cohen, S., & Wills, T. A. (1985). Stress, social support, and the buffering hypothesis. Psychological Bulletin, 98, 310–357.CrossRefPubMed

Conger, A. J. (1974). A revised definition for suppressor variables: A guide to their identification and interpretation. Educational and Psychological Measurement, 34, 35–46.CrossRef

Cramer, J. A., Benedict, A., Muszbek, N., Keskinaslan, A., & Khan, Z. M. (2008). The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: A review. International Journal of Clinical Practice, 62, 76–87.CrossRefPubMedCentralPubMed

DiMatteo, M. R. (2004). Social support and patient adherence to medical treatment: A meta-analysis. Health Psychology, 23, 207–218.CrossRefPubMed

DiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000). Depression is a risk factor for noncompliance with medical treatment: Meta-analysis of the effects of anxiety and depression on patient adherence. Archives of Internal Medicine, 160, 2101–2107.CrossRefPubMed

Egede, L. E., Gebregziabher, M., Dismuke, C. E., Lynch, C. P., Axon, R. N., Zhao, Y., & Mauldin, P. D. (2012). Medication nonadherence in diabetes: Longitudinal effects on costs and potential cost savings from improvement. Diabetes Care, 35, 2533–2539.CrossRefPubMedCentralPubMed

Egede, L. E., Gebregziabher, M., Hunt, K. J., Axon, R. N., Echols, C., Gilbert, G. E., & Mauldin, P. D. (2011). Regional, geographic, and racial/ethnic variation in glycemic control in a national sample of veterans with diabetes. Diabetes Care, 34, 938–943.CrossRefPubMedCentralPubMed

Egede, L. E., Lynch, C. P., Gebregziabher, M., Hunt, K. J., Echols, C., Gilbert, G. E., & Mauldin, P. D. (2013). Differential impact of longitudinal medication non-adherence on mortality by race/ethnicity among veterans with diabetes. Journal of General Internal Medicine, 28, 208–215.CrossRefPubMedCentralPubMed

Egede, L. E., & Osborn, C. Y. (2010). Role of motivation in the relationship between depression, self-care, and glycemic control in adults with type 2 diabetes. Diabetes Educator, 36, 276–283.CrossRefPubMedCentralPubMed

Farmer, K. C. (1999). Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clinical Therapy, 21(6), 1074–1090 (discussion 1073).

Fisher, L., Chesla, C. A., Mullan, J. T., Skaff, M. M., & Kanter, R. A. (2001). Contributors to depression in Latino and European-American patients with type 2 diabetes. Diabetes Care, 24, 1751–1757.CrossRefPubMed

Glasgow, R. E., & Toobert, D. J. (1988). Social environment and regimen adherence among type II diabetic patients. Diabetes Care, 11, 377–386.CrossRefPubMed

Gonzalez, J. S., Safren, S. A., Cagliero, E., Wexler, D. J., Delahanty, L., & Wittenberg, E. (2007). Depression, self-care, and medication adherence in type 2 diabetes relationships across the full range of symptom severity. Diabetes Care, 30, 2222–2227.CrossRefPubMed

Gonzalez, J. S., Schneider, H. E., Wexler, D. J., Psaros, C., Delahanty, L. M., Cagliero, E., & Safren, S. A. (2013). Validity of medication adherence self-reports in adults with type 2 diabetes. Diabetes Care, 36, 831–837.CrossRefPubMedCentralPubMed

Griffith, L. S., Field, B. J., & Lustman, P. J. (1990). Life stress and social support in diabetes: Association with glycemic control. International Journal of Psychiatry in Medicine, 20, 365–372.CrossRefPubMed

Hansen, R. A., Kim, M. M., Song, L., Tu, W., Wu, J., & Murray, M. D. (2009). Comparison of methods to assess medication adherence and classify nonadherence. Annals of Pharmacotherapy, 43, 413–422.CrossRefPubMed

Harrell, F. E. (2001). Regression modeling strategies: With applications to linear models, logistic regression, and survival analysis. New York: Springer.CrossRef

Heisler, M., Faul, J. D., Hayward, R. A., Langa, K. M., Blaum, C., & Weir, D. (2007). Mechanisms for racial and ethnic disparities in glycemic control in middle-aged and older Americans in the health and retirement study. Archives of Internal Medicine, 167, 1853–1860.CrossRefPubMed

Henry, S. L., Rook, K. S., Stephens, M. A., & Franks, M. M. (2013). Spousal undermining of older diabetic patients’ disease management. Journal of Health Psychology, 18, 1550–1561.CrossRefPubMed

Ho, P. M., Rumsfeld, J. S., Masoudi, F. A., McClure, D. L., Plomondon, M. E., Steiner, J. F., & Magid, D. J. (2006). Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus. Archives of Internal Medicine, 166, 1836–1841.CrossRefPubMed

Holmbeck, G. N. (2002). Post-hoc probing of significant moderational and mediational effects in studies of pediatric populations. Journal of Pediatric Psychology, 27, 87–96.CrossRefPubMed

Hong, J. S., & Kang, H. C. (2011). Relationship between oral antihyperglycemic medication adherence and hospitalization, mortality, and healthcare costs in adult ambulatory care patients with type 2 diabetes in South Korea. Medical Care, 49, 378–384.PubMed

Jeon, Y. H., Essue, B., Jan, S., Wells, R., & Whitworth, J. A. (2009). Economic hardship associated with managing chronic illness: A qualitative inquiry. BMC Health Services Research, 9, 182.CrossRefPubMedCentralPubMed

Jiang, L., Beals, J., Whitesell, N. R., Roubideaux, Y., & Manson, S. M. (2008). Stress burden and diabetes in two American Indian reservation communities. Diabetes Care, 31, 427–429.CrossRefPubMed

Johnson, V. R., Jacobson, K. L., Gazmararian, J. A., & Blake, S. C. (2010). Does social support help limited-literacy patients with medication adherence? A mixed methods study of patients in the Pharmacy Intervention for Limited Literacy (PILL) Study. Patient Education and Counseling, 79, 14–24.CrossRefPubMed

Kim, N., Agostini, J. V., & Justice, A. C. (2010). Refill adherence to oral hypoglycemic agents and glycemic control in veterans. Annals of Pharmacotherapy, 44, 800–808.CrossRefPubMedCentralPubMed

Krapek, K., King, K., Warren, S. S., George, K. G., Caputo, D. A., Mihelich, K., et al. (2004). Medication adherence and associated hemoglobin A1c in type 2 diabetes. Annals of Pharmacotherapy, 38, 1357–1362.CrossRefPubMed

Kripalani, S., Risser, J., Gatti, M. E., & Jacobson, T. A. (2009). Development and evaluation of the Adherence to Refills and Medications Scale (ARMS) among low-literacy patients with chronic disease. Value Health, 12, 118–123.CrossRefPubMed

Kroenke, K., Spitzer, R., & Williams, J. W. (2001). The PHQ-9. Journal of General Internal Medicine, 16, 606–613.CrossRefPubMedCentralPubMed

Lee, S. Y., Arozullah, A. M., Cho, Y. I., Crittenden, K., & Vicencio, D. (2009). Health literacy, social support, and health status among older adults. Educational Gerontology, 35, 191–201.CrossRef

Littlefield, C. H., Rodin, G. M., Murray, M. A., & Craven, J. L. (1990). Influence of functional impairment and social support on depressive symptoms in persons with diabetes. Health Psychology, 9, 737–749.CrossRefPubMed

Liu, H., Golin, C. E., Miller, L. G., Hays, R. D., Beck, C. K., Sanandaji, S., et al. (2001). A comparison study of multiple measures of adherence to HIV protease inhibitors. Annals of Internal Medicine, 134, 968–977.CrossRefPubMed

Mayberry, L. S., Gonzalez, J. S., Wallston, K. A., Kripalani, S., & Osborn, C. Y. (2013). The ARMS-D out performs the SDSCA, but both are reliable, valid, and predict glycemic control. Diabetes Research and Clinical Practice, 102, 96–104.CrossRefPubMedCentralPubMed

Mayberry, L. S., & Osborn, C. Y. (2012). Family support, medication adherence, and glycemic control among adults with type 2 diabetes. Diabetes Care, 35, 1239–1245.CrossRefPubMedCentralPubMed

Mayberry, L. S., & Osborn, C. Y. (2014). Family involvement is helpful and harmful to patients’ self-care and glycemic control. Patient Education and Counseling, 97, 418–425.

Mendenhall, E., Shivashankar, R., Tandon, N., Ali, M. K., Narayan, K. M., & Prabhakaran, D. (2012). Stress and diabetes in socioeconomic context: A qualitative study of urban Indians. Social Science and Medicine, 75, 2522–2529.CrossRefPubMedCentralPubMed

Naranjo, D. M., Fisher, L., Arean, P. A., Hessler, D., & Mullan, J. (2011). Patients with type 2 diabetes at risk for major depressive disorder over time. The Annals of Family Medicine, 9, 115–120.CrossRef

Ngo-Metzger, Q., Sorkin, D. H., Billimek, J., Greenfield, S., & Kaplan, S. H. (2012). The effects of financial pressures on adherence and glucose control among racial/ethnically diverse patients with diabetes. Journal of General Internal Medicine, 27, 432–437.CrossRefPubMedCentralPubMed

Osborn, C. Y., Cavanaugh, K., Wallston, K. A., Kripalani, S., Elasy, T. A., Rothman, R. L., & White, R. O. (2011). Health literacy explains racial disparities in diabetes medication adherence. Journal of Health Communication, 16, 268–278.CrossRefPubMedCentralPubMed

Osborn, C. Y., & Egede, L. E. (2012). The relationship between depressive symptoms and medication nonadherence in type 2 diabetes: The role of social support. General Hospital Psychiatry, 34, 249–253.CrossRefPubMedCentralPubMed

Osborn, C. Y., Mayberry, L. S., Wagner, J. A., & Welch, G. W. (2014). Stressors may compromise medication adherence among adults with diabetes and low socioeconomic status. Western Journal of Nursing Research, 36, 1091–1110.CrossRefPubMed

Rook, K. S. (1998). Investigating the positive and negative sides of personal relationships: Through a lens darkly. In B. H. Spitzberg & W. R. Cupach (Eds.), The dark side of close relationships (pp. 369–393). Mahwah, NJ: Lawrence Erlbaum Associates Publishers.

Rosland, A. M., Heisler, M., Choi, H. J., Silveira, M. J., & Piette, J. D. (2010). Family influences on self-management among functionally independent adults with diabetes or heart failure: Do family members hinder as much as they help? Chronic Illn, 6, 22–33.CrossRefPubMedCentralPubMed

Rothberg, M., Duval, T., Luciano, G., Frederici, J., & Welch, G. W. (2011). A scale for measuring social stress among diabetic patients. Paper presented at the 34th Society of General Internal Medicine scientific meeting, Phoenix, AZ.

Salas, M., Hughes, D., Zuluaga, A., Vardeva, K., & Lebmeier, M. (2009). Costs of medication nonadherence in patients with diabetes mellitus: A systematic review and critical analysis of the literature. Value Health, 12, 915–922.CrossRefPubMed

Schafer, L. C., Mccaul, K. D., & Glasgow, R. E. (1986). Supportive and nonsupportive family behaviors—Relationships to adherence and metabolic control in persons with type-I diabetes. Diabetes Care, 9, 179–185.CrossRefPubMed

Spencer, M. S., Kieffer, E. C., Sinco, B. R., Palmisano, G., Guzman, J. R., & James, S. A. (2006). Diabetes-specific emotional distress among African Americans and Hispanics with type 2 diabetes. Journal of Health Care for the Poor and Underserved, 17, 88–105.CrossRefPubMed

Steiner, J. F., & Prochazka, A. V. (1997). The assessment of refill compliance using pharmacy records: Methods, validity, and applications. Journal of Clinical Epidemiology, 50, 105–116.CrossRefPubMed

Stephens, M. A. P., Franks, M. M., Rook, K. S., Iida, M., Hemphill, R. C., & Salem, J. K. (2013). Spouses’ attempts to regulate day-to-day dietary adherence among patients with type 2 diabetes. Health Psychology, 32, 1029–1037.CrossRefPubMed

Thoits, P. A. (2011). Mechanisms linking social ties and support to physical and mental health. Journal of Health and Social Behavior, 52, 145–161.CrossRefPubMed

Thomas, J. L., Jones, G. N., Scarinci, I. C., & Brantley, P. J. (2007). Social support and the association of type 2 diabetes and depressive and anxiety disorders among low-income adults seen in primary care clinics. Journal of Clinical Psychology in Medical Settings, 14, 351–359.CrossRef

Twist, K., Stahl, D., Amiel, S. A., Thomas, S., Winkley, K., & Ismail, K. (2013). Comparison of depressive symptoms in type 2 diabetes using a two-stage survey design. Psychosomatic Medicine, 75, 791–797.CrossRefPubMed

van Steenbergen-Weijenburg, K. M., de Vroege, L., Ploeger, R. R., Brals, J. W., Vloedbeld, M. G., Veneman, T. F., et al. (2010). Validation of the PHQ-9 as a screening instrument for depression in diabetes patients in specialized outpatient clinics. BMC Health Services Research, 10, 235.CrossRefPubMedCentralPubMed

Velicer, W. F. (1978). Suppressor variables and the semipartial correlation coefficient. Educational and Psychological Measurement, 38, 953–958.CrossRef

Welch, G. W., Osborn, C. Y., Rotherber, M., Zagarins, S. E., White, R. O., & Friderici, J. (2011). Level of social distress among Mexican and Puerto Rican American diabetes patients and relationship to glycemic control. Paper presented at the 71st annual scientific session of the American Diabetes Association, San Diego, CA.

Wolfe, R., & Gould, W. (1998). sg76: An approximate likelihood-ratio test for ordinal response models. Stata Technical Bulletin, 42, 24–27.

Titel: Stress, depression and medication nonadherence in diabetes: test of the exacerbating and buffering effects of family support
Auteurs: Lindsay Satterwhite Mayberry
Leonard E. Egede
Julie A. Wagner
Chandra Y. Osborn
Publicatiedatum: 01-04-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Behavioral Medicine / Uitgave 2/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-014-9611-4

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