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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2009

01-05-2009 | Original Paper

Standardizing ADOS Scores for a Measure of Severity in Autism Spectrum Disorders

Auteurs: Katherine Gotham, Andrew Pickles, Catherine Lord

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2009

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Abstract

The aim of this study is to standardize Autism Diagnostic Observation Schedule (ADOS) scores within a large sample to approximate an autism severity metric. Using a dataset of 1,415 individuals aged 2–16 years with autism spectrum disorders (ASD) or nonspectrum diagnoses, a subset of 1,807 assessments from 1,118 individuals with ASD were divided into narrow age and language cells. Within each cell, severity scores were based on percentiles of raw totals corresponding to each ADOS diagnostic classification. Calibrated severity scores had more uniform distributions across developmental groups and were less influenced by participant demographics than raw totals. This metric should be useful in comparing assessments across modules and time, and identifying trajectories of autism severity for clinical, genetic, and neurobiological research.

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Metagegevens
Titel
Standardizing ADOS Scores for a Measure of Severity in Autism Spectrum Disorders
Auteurs
Katherine Gotham
Andrew Pickles
Catherine Lord
Publicatiedatum
01-05-2009
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0674-3