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Gepubliceerd in: Journal of Autism and Developmental Disorders 10/2018

04-05-2018 | Original Paper

Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2018

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Abstract

The relationship between brain development and clinical heterogeneity in autism (ASD) is unknown. This study examines the Social Responsiveness Scale (SRS) in relation to the longitudinal development of cortical thickness. Participants (N = 91 ASD, N = 56 TDC; 3–39 years at first scan) were scanned up to three times over a 7-year period. Mixed-effects models examined cortical thickness in relation to SRS score. ASD participants with higher SRS scores showed regionally increased age-related cortical thinning. Regional thickness differences and reduced age-related cortical thinning were found in predominantly right lateralized regions in ASD with decreasing SRS scores over time. Our findings emphasize the importance of examining clinical phenotypes in brain-based studies of ASD.
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Literatuur
go back to reference Akaike, H. (1974). A new look at the statistical model identification. IEEE Transactions on Automatic Control, 19, 716–723.CrossRef Akaike, H. (1974). A new look at the statistical model identification. IEEE Transactions on Automatic Control, 19, 716–723.CrossRef
go back to reference American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC, American Psychiatric Association. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC, American Psychiatric Association.
go back to reference Constantino, J. N. (2002). The Social Responsiveness Scale. Los Angeles: Western Psychological Services. Constantino, J. N. (2002). The Social Responsiveness Scale. Los Angeles: Western Psychological Services.
go back to reference Constantino, J. N., et al. (2003). Validation of a brief quantitative measure of autistic traits: Comparison of the social responsiveness scale with the autism diagnostic interview-revised. Journal of Autism and Developmental Disorders 33, 427–433.CrossRef Constantino, J. N., et al. (2003). Validation of a brief quantitative measure of autistic traits: Comparison of the social responsiveness scale with the autism diagnostic interview-revised. Journal of Autism and Developmental Disorders 33, 427–433.CrossRef
go back to reference Constantino, J. N., Przybeck, T., Friesen, D., & Todd, R. D. (2000). Reciprocal social behavior in children with and without pervasive developmental disorders. Journal of Developmental and Behavioral Pediatrics: JDBP, 21, 2–11.CrossRef Constantino, J. N., Przybeck, T., Friesen, D., & Todd, R. D. (2000). Reciprocal social behavior in children with and without pervasive developmental disorders. Journal of Developmental and Behavioral Pediatrics: JDBP, 21, 2–11.CrossRef
go back to reference Hardan, A. Y., Muddasani, S., Vemulapalli, M., Keshavan, M. S., & Minshew, N. J. (2006). An MRI study of increased cortical thickness in autism. American Journal of Psychiatry, 163, 1290–1292.CrossRef Hardan, A. Y., Muddasani, S., Vemulapalli, M., Keshavan, M. S., & Minshew, N. J. (2006). An MRI study of increased cortical thickness in autism. American Journal of Psychiatry, 163, 1290–1292.CrossRef
go back to reference Hyde, K. L., Samson, F., Evans, A. C., & Mottron, L. (2010). Neuroanatomical differences in brain areas implicated in perceptual and other core features of autism revealed by cortical thickness analysis and voxel-based morphometry. Human Brain Mapping 31, 556–566. https://doi.org/10.1002/hbm.20887.CrossRefPubMed Hyde, K. L., Samson, F., Evans, A. C., & Mottron, L. (2010). Neuroanatomical differences in brain areas implicated in perceptual and other core features of autism revealed by cortical thickness analysis and voxel-based morphometry. Human Brain Mapping 31, 556–566. https://​doi.​org/​10.​1002/​hbm.​20887.CrossRefPubMed
go back to reference Kraemer, H. C., Yesavage, J. A., Taylor, J. L., & Kupfer, D. (2000). How can we learn about developmental processes from cross-sectional studies, or can we?. American Journal of Psychiatry, 157, 163–171.CrossRef Kraemer, H. C., Yesavage, J. A., Taylor, J. L., & Kupfer, D. (2000). How can we learn about developmental processes from cross-sectional studies, or can we?. American Journal of Psychiatry, 157, 163–171.CrossRef
go back to reference Lainhart, J. E., et al. (2006). Head circumference and height in autism: A study by the Collaborative Program of Excellence in Autism. American Journal of Medical Genetics, 140, 2257–2274.CrossRef Lainhart, J. E., et al. (2006). Head circumference and height in autism: A study by the Collaborative Program of Excellence in Autism. American Journal of Medical Genetics, 140, 2257–2274.CrossRef
go back to reference Lord, C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders 30, 205–223.CrossRef Lord, C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders 30, 205–223.CrossRef
go back to reference Lord, M., Rutter, A., & LeCouteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.CrossRef Lord, M., Rutter, A., & LeCouteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.CrossRef
go back to reference Ohta, H., Nordahl, C. W., Iosif, A. M., Lee, A., Rogers, S., & Amaral, D. G. (2016). Increased surface area, but not cortical thickness, in a subset of young boys with autism spectrum disorder. Autism Research: Official Journal of the International Society for Autism Research 9, 232–248. https://doi.org/10.1002/aur.1520.CrossRef Ohta, H., Nordahl, C. W., Iosif, A. M., Lee, A., Rogers, S., & Amaral, D. G. (2016). Increased surface area, but not cortical thickness, in a subset of young boys with autism spectrum disorder. Autism Research: Official Journal of the International Society for Autism Research 9, 232–248. https://​doi.​org/​10.​1002/​aur.​1520.CrossRef
go back to reference R Core Team. (2015). R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing. R Core Team. (2015). R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing.
go back to reference Tu, P. C., Hsu, J. W., Lan, C. C., Liu, C. C., Su, T. P., & Chen, Y. S. (2016). Structural and functional correlates of a quantitative autistic trait measured using the social responsive scale in neurotypical male adolescents. Autism Research: Official Journal of the International Society for Autism Research, 9, 570–578. https://doi.org/10.1002/aur.1535.CrossRef Tu, P. C., Hsu, J. W., Lan, C. C., Liu, C. C., Su, T. P., & Chen, Y. S. (2016). Structural and functional correlates of a quantitative autistic trait measured using the social responsive scale in neurotypical male adolescents. Autism Research: Official Journal of the International Society for Autism Research, 9, 570–578. https://​doi.​org/​10.​1002/​aur.​1535.CrossRef
Metagegevens
Titel
Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder
Publicatiedatum
04-05-2018
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2018
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-018-3566-1

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