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Gepubliceerd in: Quality of Life Research 6/2020

Open Access 07-01-2020

Social inequalities in health-related quality of life among people aging with HIV/AIDS: the role of comorbidities and disease severity

Auteurs: Jochen Drewes, Jennifer Ebert, Phil C. Langer, Dieter Kleiber, Burkhard Gusy

Gepubliceerd in: Quality of Life Research | Uitgave 6/2020

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Abstract

Purpose

While socioeconomic inequalities in health-related quality of life are well documented in the scientific literature, research has neglected to look into the reasons for these inequalities. The purpose of this study is to determine in what way social inequalities in health-related quality of life among patients with the same chronic disease could be explained by variations in disease severity.

Methods

We used the data of 748 people aging with HIV in Germany who took part in the nationwide study 50plushiv and provided self-report data on socioeconomic status, health-related quality of life (SF-12) and various markers of disease severity (comorbidity, falls, late presentation and AIDS diagnosis). Regression analyses were applied to determine the impact of SES on HRQOL after adjusting for disease severity variables.

Results

The mental and physical subscales of the SF-12, comorbidity burden and falls were significantly related to SES. SES explained 7% of the variance in PCS scores and 3% of the variance in MCS scores after adjusting for age and time since diagnosis. Markers of disease severity explained 33% of the variance in PCS scores and 14% of the variance in MCS scores. After adjusting for disease severity SES was still significantly related to PCS and MCS scores.

Conclusions

The diverse sample of people aging with HIV showed social inequalities regarding HRQOL and most of the disease severity markers. SES was significantly related to mental and physical HRQOL after adjusting for disease severity. Possible explanations for this phenomenon are discussed.
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Metagegevens
Titel
Social inequalities in health-related quality of life among people aging with HIV/AIDS: the role of comorbidities and disease severity
Auteurs
Jochen Drewes
Jennifer Ebert
Phil C. Langer
Dieter Kleiber
Burkhard Gusy
Publicatiedatum
07-01-2020
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 6/2020
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02413-9