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04-01-2021 | Original Paper

Sex Differences in Co-occurring Conditions Among Autistic Children and Youth in Florida: A Retrospective Cohort Study (2012–2019)

Auteurs: Amber M. Angell, Alexis Deavenport-Saman, Larry Yin, Baiming Zou, Chen Bai, Deepthi Varma, Olga Solomon

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2021

Abstract

Autistic children have a high prevalence of co-occurring mental health, developmental/behavioral, and medical conditions, but research on sex/gender differences has been mixed. We used Florida healthcare claims data to characterize sex differences (female/male) in co-occurring conditions among autistic children ages 1–21 (N = 83,500). After adjusting for age, race, ethnicity, urbanicity, and insurance, autistic girls had significantly higher odds of anxiety disorders, mood disorders, intellectual disability, developmental disorders, epilepsy, metabolic disorders, gastrointestinal disorders, and sleep disorders compared to autistic boys. Autistic girls had significantly lower odds of ADHD. The findings contribute to the growing body of research on the unique healthcare needs of autistic girls.

vorige artikel Acquisition and Use of ‘Priors’ in Autism: Typical in Deciding Where to Look, Atypical in Deciding What Is There

volgende artikel Brief Report: Impact of COVID-19 on Individuals with ASD and Their Caregivers: A Perspective from the SPARK Cohort

We use identity-first language because it is the preference of many in the autism community (Dunn and Andrews 2015; Gernsbacher 2017; Kenny et al. 2015).

https://doi.org/10.6084/m9.figshare.8063567.v2.

Amiet, C., Gourfinkel-An, I., Bouzamondo, A., Tordjman, S., Baulac, M., Lechat, P., et al. (2008). Epilepsy in autism is associateed with intellectual disability and gender: Evidence from a meta-analysis. Biological Psychiatry, 64(7), 577–582. https://doi.org/10.1016/j.biopsych.2008.04.030. CrossRefPubMed

Atladóttir, H. Ó., Pedersen, M. G., Thorsen, P., Mortensen, P. B., Deleuran, B., Eaton, W. W., & Parner, E. T. (2009). Association of family history of autoimmune diseases and autism spectrum disorders. Pediatrics, 124(2), 687–694. https://doi.org/10.1542/peds.2008-2445. CrossRefPubMed

Bauman, M. L. (2010). Medical comorbidities in autism: Challenges to diagnosis and treatment. Neurotherapeutics, 7(3), 320–327. https://doi.org/10.1016/j.nurt.2010.06.001. CrossRefPubMedCentralPubMed

Benevides, T. W., Carretta, H. J., & Lane, S. J. (2015). Unmet need for therapy among children with autism spectrum disorder: Results from the 2005–2006 and 2009–2010 National Survey of Children with Special Health Care Needs. Maternal and Child Health Journal. https://doi.org/10.1007/s10995-015-1876-x. CrossRef

Brookman-Frazee, L., Stadnick, N., Chlebowski, C., Baker-Ericzén, M., & Ganger, W. (2018). Characterizing psychiatric comorbidity in children with autism spectrum disorder receiving publicly funded mental health services. Autism, 22(8), 938–952. https://doi.org/10.1177/1362361317712650. CrossRefPubMed

Buie, T., Fuchs, G. J., Furuta, G. T., Kooros, K., Levy, J., Lewis, J. D., et al. (2010). Recommendations for evaluation and treatment of common gastrointestinal problems in children with ASDs. Pediatrics. https://doi.org/10.1542/peds.2009-1878D. CrossRefPubMed

Burke, J. P., Jain, A., Yang, W., Kelly, J. P., Kaiser, M., Becker, L., et al. (2014). Does a claims diagnosis of autism mean a true case? Autism, 18(3), 321–330. https://doi.org/10.1177/1362361312467709. CrossRefPubMed

Carpenter, B., Happe, F., & Egerton, J. (Eds.). (2019). Girls and autism: Educational, family and personal perspectives. New York: Routledge.

Cidav, Z., Marcus, S. C., & Mandell, D. S. (2014). Home- and community-based waivers for children with autism: Effects on service use and costs. Intellectual and Developmental Disabilities, 52(4), 239–248. https://doi.org/10.1352/1934-9556-52.4.239. CrossRefPubMedCentralPubMed

Dunn, D. S., & Andrews, E. E. (2015). Peron-first and identity-first language: Developing psychologists’ cultural competence using disability language. American Psychologist, 70(3), 255–264. https://doi.org/10.1037/a0038636. CrossRefPubMed

Elixhauser, A., Steiner, C., & Palmer, L. (2015). Healthcare Cost and Utilization Project Clinical Classifications Software (CCS) for ICD-9-CM. Retrieved from http://www.hcup-us.ahrq.gov/toolssoftware/ccs/ccs.jsp.

Elixhauser, A., Steiner, C., & Palmer, L. (2016). Healthcare Cost and Utilization Project Clinical Classifications Software (CCS) for ICD-10-PCS (beta version). Retrieved from https://www.hcup-us.ahrq.gov/toolssoftware/ccs10/ccs10.jsp#overview.

Frazier, T. W., Georgiades, S., Bishop, S. L., & Hardan, A. Y. (2014). Behavioral and cognitive characteristics of females and males with autism in the Simons Simplex Collection. Journal of the American Academy of Child and Adolescent Psychiatry, 53(3), 329-340.e3. https://doi.org/10.1016/j.neuroimage.2013.08.045.The. CrossRefPubMed

Gernsbacher, M. A. (2017). Editorial perspective: The use of person-first language in scholarly writing may accentuate stigma. Journal of Child Psychology and Psychiatry and Allied Disciplines, 58(7), 859–861. https://doi.org/10.1111/jcpp.12706. CrossRefPubMed

Giarelli, E., Wiggins, L. D., Rice, C. E., Levy, S. E., Kirby, R. S., Pinto-Martin, J., & Mandell, D. (2010). Sex differences in the evaluation and diagnosis of autism spectrum disorders among children. Disability and Health Journal, 3(2), 107–116. https://doi.org/10.1016/j.dhjo.2009.07.001. CrossRefPubMed

Goldman, S. E., Richdale, A. L., Clemons, T., & Malow, B. A. (2012). Parental sleep concerns in autism spectrum disorders: Variations from childhood to adolescence. Journal of Autism and Developmental Disorders, 42(4), 531–538. https://doi.org/10.1007/s10803-011-1270-5. CrossRefPubMed

Gorrindo, P., Williams, K. C., Lee, E. B., Walker, L. S., McGrew, S. G., & Levitt, P. (2012). Gastrointestinal dysfunction in autism: Parental report, clinical evaluation, and associated factors. Autism Research, 5(2), 101–108. https://doi.org/10.1002/aur.237. CrossRefPubMedCentralPubMed

Gotham, K., Brunwasser, S. M., & Lord, C. (2015). Depressive and anxiety symptom trajectories from school-age through young adulthood in samples with autism spectrum disorder and developmental delay. Journal of the American Academy of Child and Adolescent Psychiatry, 54(5), 369-376.e3. https://doi.org/10.1016/j.jaac.2015.02.005. CrossRefPubMedCentralPubMed

Greven, C. U., Richards, J. S., & Buitelaar, J. K. (2018). Sex differences in ADHD. In T. Banaschewski, D. Coghill, & A. Zuddas (Eds.), Oxford textbook of attention deficit hyperactivity disorder (pp. 154–160). Oxford: Oxford University Press.

Hartley, S. L., & Sikora, D. M. (2009). Sex differences in autism spectrum disorder: An examination of developmental functioning, autistic symptoms, and coexisting behavior problems in toddlers. Journal of Autism and Developmental Disorders, 39(12), 1715–1722. https://doi.org/10.1007/s10803-009-0810-8. CrossRefPubMedCentralPubMed

Hudson, C. C., Hall, L., & Harkness, K. L. (2019). Prevalence of depressive disorders in individuals with autism spectrum disorder: A meta-analysis. Journal of Abnormal Child Psychology, 47(1), 165–175. https://doi.org/10.1007/s10802-018-0402-1. CrossRefPubMed

Hyman, S. L., Levy, S. E., & Myers, S. M. (2020). Identification, evaluation, and management of children with autism spectrum disorder. Pediatrics. https://doi.org/10.1542/peds.2019-3447. CrossRefPubMed

Joshi, G., Petty, C., Wozniak, J., Henin, A., Fried, R., Galdo, M., et al. (2010). The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: A large compmarative study of a psychiatrially referred population. Journal of Autism & Developmental Disorders, 40, 1361–1370. https://doi.org/10.1007/s10803-010-0996-9. CrossRef

Kenny, L., Hattersley, C., Molins, B., Buckley, C., Povey, C., & Pellicano, E. (2015). Which terms should be used to describe autism? Perspectives from the UK autism community. Autism, 20(4), 442–462. https://doi.org/10.1177/1362361315588200. CrossRefPubMed

Kentrou, V., de Veld, D. M. J., Mataw, K. J. K., & Begeer, S. (2019). Delayed autism spectrum disorder recognition in children and adolescents previously diagnosed with attention-deficit/hyperactivity disorder. Autism, 23(4), 1065–1072. https://doi.org/10.1177/1362361318785171. CrossRefPubMed

Kirkovski, M., Enticott, P. G., & Fitzgerald, P. B. (2013). A review of the role of female gender in autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(11), 2584–2603. https://doi.org/10.1007/s10803-013-1811-1. CrossRefPubMed

Lai, M. C., & Szatmari, P. (2019). Sex and gender impacts on the behavioural presentation and recognition of autism. Current Opinion in Psychiatry, 33(2), 117–123. https://doi.org/10.1097/YCO.0000000000000575. CrossRef

Lawson, L. P., Richdale, A. L., Haschek, A., Flower, R. L., Vartuli, J., Arnold, S. R. C., & Trollor, J. N. (2020). Cross-sectional and longitudinal predictors of quality of life in autistic individuals from adolescence to adulthood: The role of mental health and sleep quality. Autism, 24(4), 954–967. https://doi.org/10.1177/1362361320908107. CrossRefPubMed

Lindly, O. J., Zuckerman, K. E., & Kuhlthau, K. A. (2018). Healthcare access and services use among US children with autism spectrum disorder. Autism. https://doi.org/10.1177/1362361318815237. CrossRefPubMedCentralPubMed

Lukmanji, S., Manji, S. A., Kadhim, S., Sauro, K. M., Wirrell, E. C., Kwon, C. S., & Jetté, N. (2019). The co-occurrence of epilepsy and autism: A systematic review. Epilepsy and Behavior, 98, 238–248. https://doi.org/10.1016/j.yebeh.2019.07.037. CrossRefPubMed

Malow, B. A., Katz, T., Reynolds, A. M., Shui, A., Carno, M., Connolly, H. V., et al. (2016). Sleep difficulties and medications in children with autism spectrum disorders: A registry study. Pediatrics, 137(Supplement), S98–S104. https://doi.org/10.1542/peds.2015-2851H. CrossRefPubMed

Mandy, W., Chilvers, R., Chowdhury, U., Salter, G., Seigal, A., & Skuse, D. (2012). Sex differences in autism spectrum disorder: Evidence from a large sample of children and adolescents. Journal of Autism and Developmental Disorders, 42(7), 1304–1313. https://doi.org/10.1007/s10803-011-1356-0. CrossRefPubMed

Mandy, W., Gillberg, C. I., Hamdani, Y., Lunsky, Y., Kassee, C., Nafeh, F., et al. (2018). The female autism phenotype: New methods, new discoveries. Rotterdam: In International Society for Autism Research.

Mannion, A., & Leader, G. (2013). An analysis of the predictors of comorbid psychopathology, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder. Research in Autism Spectrum Disorders, 7(12), 1663–1671. https://doi.org/10.1016/j.rasd.2013.10.002. CrossRef

Margari, L., Palumbi, R., Peschechera, A., Craig, F., De Giambattista, C., Ventura, P., & Margari, F. (2019). Sex-gender comparisons in comorbidities of children and adolescents with high-functioning autism spectrum disorder. Frontiers in Psychiatry, 10(March), 1–5. https://doi.org/10.3389/fpsyt.2019.00159. CrossRef

May, T., Cornish, K., & Rinehart, N. (2014). Does gender matter? A one year follow-up of autistic, attention and anxiety symptoms in high-functioning children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(5), 1077–1086. https://doi.org/10.1007/s10803-013-1964-y. CrossRefPubMed

Mosner, M. G., Kinard, J. L., Shah, J. S., McWeeny, S., Greene, R. K., Lowery, S. C., et al. (2019). Rates of co-occurring psychiatric disorders in autism spectrum disorder using the Mini International Neuropsychiatric Interview. Journal of Autism and Developmental Disorders, 49(9), 3819–3832. https://doi.org/10.1007/s10803-019-04090-1. CrossRefPubMedCentralPubMed

Rosen, T. E., Mazefsky, C. A., Vasa, R. A., & Lerner, M. D. (2018). Co-occurring psychiatric conditions in autism spectrum disorder. International Review of Psychiatry, 30(1), 40–61. https://doi.org/10.1080/09540261.2018.1450229. CrossRefPubMed

Shenkman, E., Hurt, M., Hogan, W., Carrasquillo, O., Smith, S., Brickman, A., & Nelson, D. (2018). OneFlorida clinical research consortium: Linking a clinical and translational science institute with a community-based distributive medical education model. Academic Medicine, 93(3), 451–455. https://doi.org/10.1097/acm.0000000000002029. CrossRefPubMed

Solomon, M., Miller, M., Taylor, S. L., Hinshaw, S. P., & Carter, C. S. (2012). Autism symptoms and internalizing psychopathology in girls and boys with autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(1), 48–59. https://doi.org/10.1007/s10803-011-1215-z. CrossRefPubMed

Stacy, M. E., Zablotsky, B., Yarger, H. A., Zimmerman, A., Makia, B., & Lee, L. C. (2014). Sex differences in co-occurring conditions of children with autism spectrum disorders. Autism, 18(8), 965–974. https://doi.org/10.1177/1362361313505719. CrossRefPubMed

Strang, J. F., van der Miesen, A. I. R., Caplan, R., Hughes, C., daVanport, S., & Lai, M. C. (2020). Both sex- and gender-related factors should be considered in autism research and clinical practice. Autism, 24(3), 539–543. https://doi.org/10.1177/1362361320913192. CrossRefPubMed

Supekar, K., Iyer, T., & Menon, V. (2017). The influence of sex and age on prevalence rates of comorbid conditions in autism. Autism Research, 10(5), 778–789. https://doi.org/10.1002/aur.1741. CrossRefPubMed

Thomas, S., Hovinga, M. E., Rai, D., & Lee, B. K. (2017). Brief Report: Prevalence of co-occurring epilepsy and autism spectrum disorder: The U.S. National Survey of Children’s Health 2011–2012. Journal of Autism and Developmental Disorders, 47(1), 224–229. https://doi.org/10.1007/s10803-016-2938-7. CrossRefPubMed

Tint, A., & Weiss, J. A. (2018). A qualitative study of the service experiences of women with autism spectrum disorder. Autism, 22(8), 928–937. https://doi.org/10.1177/1362361317702561. CrossRefPubMed

Tint, A., Weiss, J. A., & Lunsky, Y. (2017). Identifying the clinical needs and patterns of health service use of adolescent girls and women with autism spectrum disorder. Autism Research, 10(9), 1558–1566. https://doi.org/10.1002/aur.1806. CrossRefPubMed

U.S. Department of Agriculture. (2013). Rural-Urban Continuum Codes. Retrieved from https://www.ers.usda.gov/data-products/rural-urban-continuum-codes/.

Uljarević, M., Hedley, D., Rose-Foley, K., Magiati, I., Cai, R. Y., Dissanayake, C., et al. (2019). Anxiety and depression from adolescence to old age in autism spectrum disorder. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-019-04084-z. CrossRefPubMed

Van Wijngaarden-Cremers, P. J. M., Van Eeten, E., Groen, W. B., Van Deurzen, P. A., Oosterling, I. J., & Van Der Gaag, R. J. (2014). Gender and age differences in the core triad of impairments in autism spectrum disorders: A systematic review and meta-analysis. Journal of Autism and Developmental Disorders, 44(3), 627–635. https://doi.org/10.1007/s10803-013-1913-9. CrossRefPubMed

Young, S., Hollingdale, J., Absoud, M., Bolton, P., Branney, P., Colley, W., et al. (2020). Guidance for identification and treatment of individuals with attention deficit/hyperactivity disorder and autism spectrum disorder based upon expert consensus. BMC Medicine, 18(1), 1–29. https://doi.org/10.1186/s12916-020-01585-y. CrossRef

Zerbo, O., Leong, A., Barcellos, L., Bernal, P., Fireman, B., & Croen, L. A. (2015). Immune mediated conditions in autism spectrum disorders. Brain, Behavior, and Immunity, 46, 232–236. https://doi.org/10.1016/j.bbi.2015.02.001. CrossRefPubMedCentralPubMed

Titel: Sex Differences in Co-occurring Conditions Among Autistic Children and Youth in Florida: A Retrospective Cohort Study (2012–2019)
Auteurs: Amber M. Angell
Alexis Deavenport-Saman
Larry Yin
Baiming Zou
Chen Bai
Deepthi Varma
Olga Solomon
Publicatiedatum: 04-01-2021
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 10/2021
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-020-04841-5

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