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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-07-2012 | Original Paper

Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents

Auteurs: William Mandy, Rebecca Chilvers, Uttom Chowdhury, Gemma Salter, Anna Seigal, David Skuse

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2012

Abstract

Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females.

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Titel: Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents
Auteurs: William Mandy
Rebecca Chilvers
Uttom Chowdhury
Gemma Salter
Anna Seigal
David Skuse
Publicatiedatum: 01-07-2012
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-011-1356-0

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