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02-12-2021 | Original Paper

Sex Differences in Autism: Examining Intrinsic and Extrinsic Factors in Children and Adolescents Enrolled in a National ASD Cohort

Auteurs: Emily F. Dillon, Stephen Kanne, Rebecca J. Landa, Robert Annett, Raphael Bernier, Catherine Bradley, Laura Carpenter, So Hyun Kim, Julia Parish-Morris, Robert Schultz, Ericka L. Wodka, the SPARK consortium

Gepubliceerd in: Journal of Autism and Developmental Disorders

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Abstract

Discernment of possible sex-based variations in presentations of autism spectrum disorder (ASD) symptoms is limited by smaller female samples with ASD and confounds with ASD ascertainment. A large national cohort of individuals with autism, SPARK, allowed parent report data to be leveraged to examine whether intrinsic child characteristics and extrinsic factors differentially impact males and females with ASD. Small but consistent sex differences in individuals with ASD emerged related to both intrinsic and extrinsic factors, with different markers for males and females. Language concerns in males may make discernment of ASD more straightforward, while early motor concerns in females may hamper diagnosis as such delays are not identified within traditional ASD diagnostic criteria.
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Metagegevens
Titel
Sex Differences in Autism: Examining Intrinsic and Extrinsic Factors in Children and Adolescents Enrolled in a National ASD Cohort
Auteurs
Emily F. Dillon
Stephen Kanne
Rebecca J. Landa
Robert Annett
Raphael Bernier
Catherine Bradley
Laura Carpenter
So Hyun Kim
Julia Parish-Morris
Robert Schultz
Ericka L. Wodka
the SPARK consortium
Publicatiedatum
02-12-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-021-05385-y