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Journal of Autism and Developmental Disorders
Gepubliceerd in: Journal of Autism and Developmental Disorders 6/2016

12-02-2016 | Original Paper

Severity of Autism Spectrum Disorders: Current Conceptualization, and Transition to DSM-5

Auteurs: Margaret H. Mehling, Marc J. Tassé

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2016

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Abstract

Mirroring the evolution of the conceptualization of autism has been changes in the diagnostic process, including the most recent revisions to the DSM-5 and the addition of severity-based diagnostic modifiers assigned on the basis of intensity of needed supports. A review of recent literature indicates that in research stratifying individuals on the basis of autism severity, core ASD symptomology is the primary consideration. This conceptualization is disparate from the conceptualization put forth in DSM-5 in which severity determination is based on level of needed support, which is also impacted by cognitive, language, behavioral, and adaptive functioning. This paper reviews literature in this area and discusses possible instruments that may be useful to inform clinical judgment in determining ASD severity levels.
vorige artikel Three-Dimensional Kinematic Analysis of Prehension Movements in Young Children with Autism Spectrum Disorder: New Insights on Motor Impairment
volgende artikel An Evaluation of a Parent Implemented In Situ Pedestrian Safety Skills Intervention for Individuals with Autism
Literatuur
Adams, J. B., Audhya, T., McDonough-Means, S., Rubin, R. A., Quig, D., Geis, E., Gehn, E., Lee, W. (2011). Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. Nutrition & Metabolism, 8(1), 34–65.
Adams, J. B., Audhya, T., McDonough-Means, S., Rubin, R. A., Quig, D., Geis, E., et al. (2013). Toxicological status of children with autism vs. neurotypical children and the association with autism severity. Biological Trace Element Research, 151(2), 171–180.PubMedCrossRef
Adams, J. B., Baral, M., Geis, E., Mitchell, J., Ingram, J., Hensley, A., Zappia, I., El-Dahr, J. M. (2009). The severity of autism is associated with toxic metal body burden and red blood cell glutathione levels. Journal of Toxicology. doi:10.​1155/​2009/​532640.
Adams, J. B., Johansen, L. J., Powell, L. D., Quig, D., & Rubin, R. A. (2011b). Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity. Bmc Gastroenterology, 11(1), 1–13.CrossRef
Adams, H. L., Matson, J. L., Cervantes, P. E., & Goldin, R. L. (2014). The relationship between autism symptom severity and sleep problems: Should bidirectionality be considered? Research in Autism Spectrum Disorders, 8(3), 193–199.CrossRef
AL-ayadhi, L. Y., & Mostafa, G. A. (2011). Increased serum osteopontin levels in autistic children: Relation to the disease severity. Brain, Behavior, and Immunity, 25(7), 1393–1398.PubMedCrossRef
Allan, D. A., Steinberg, M., Dunn, M., Fein, D., Feinstein, C., Waterhouse, L., & Rapin, I. (2001). Autistic disorder versus other pervasive developmental disorders in young children: Same or different? European Child and Adolescent Psychiatry, 10, 67–78.CrossRef
American Educational Research Association (AERA), American Psychological Association, National Council on Measurement in Education, and Joint Committee on Standards for Educational and Psychological Testing (U.S.). (2014). Standards for educational and psychological testing.
American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: American Psychiatric Publishing.
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Publishing.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Publishing.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.
Arnold, S. C., Riches, V. C., & Stancliffe, R. J. (2014). I-CAN: The classification and prediction of support needs. Journal of Applied Research in Intellectual Disabilities, 27(2), 97–111. doi:10.​1111/​jar.​12055.PubMedCrossRef
Baghdadli, A., Picot, M. C., Pascal, C., Pry, R., & Aussilloux, C. (2003). Relationship between age of recognition of first disturbances and severity in young children with autism. European Child and Adolescent Psychiatry, 12(3), 122–127.PubMedCrossRef
Bavin, E. L., Kidd, E., Prendergast, L., Baker, E., Dissanayake, C., & Prior, M. (2014). Severity of autism is related to children’s language processing. Autism Research: Official Journal of the International Society for Autism Research, 7(6), 687–694.CrossRef
Baxter, A. C., Lotspeich, L. J., Spiker, D., Martin, J. L., Grether, J. K., & Hallmayer, J. F. (2007). Brief report: Effect of maternal age on severity of autism. Journal of Autism and Developmental Disorders, 37(5), 976–982.PubMedCrossRef
Ben-Itzchak, E., & Zachor, D. A. (2007). The effects of intellectual functioning and autism severity on outcome of early behavioral intervention for children with autism. Research in Developmental Disabilities, 28(3), 287–303.PubMedCrossRef
Benson, P. (2006). The impact of child symptom severity on depressed mood among parents of children with ASD: The mediating role of stress proliferation. Journal of Autism and Developmental Disorders, 36(5), 685–695.PubMedCrossRef
Beurkens, N. M., Hobson, J. A., & Hobson, R. P. (2013). Autism severity and qualities of parent–child relations. Journal of Autism and Developmental Disorders, 43(1), 168–178.PubMedCrossRef
Blaurock-Busch, E., Amin, O. R., Dessoki, H. H., & Rabah, T. (2012). Toxic metals and essential elements in hair and severity of symptoms among children with autism. Maedica - A Journal of Clinical Medicine, 7(1), 38–48.
Bodfish, J. W., Symons, F. W., & Lewis, M. H. (1999). The repetitive behavior scale. Western Carolina Center Research Reports.
Brandwein, A. B., Foxe, J. J., Butler, J. S., Frey, H.-P., Bates, J. C., Shulman, L. H., & Molholm, S. (2015). Neurophysiological indices of atypical auditory processing and multisensory integration are associated with symptom severity in autism. Journal of Autism and Developmental Disorders, 45(1), 230–244.PubMedPubMedCentralCrossRef
Chang, C. L., Lung, F. W., Yen, C. F., & Yang, P. (2013). Adaptive behaviors in high-functioning Taiwanese children with autism spectrum disorders: An investigation of the mediating roles of symptom severity and cognitive ability. Journal of Autism and Developmental Disorders, 43(6), 1347–1355.PubMedCrossRef
Cohen, I. L., Liu, X., Lewis, M. E., Chudley, A., Forster-Gibson, C., Gonzalez, M., et al. (2011). Autism severity is associated with child and maternal MAOA genotypes. Clinical Genetics, 79(4), 355–362.PubMedCrossRef
Cohen, I. L., Liu, X., Schutz, C., White, B. N., Jenkins, E. C., Brown, W. T., & Holden, J. J. A. (2003). Association of autism severity with a monoamine oxidase: A functional polymorphism. Clinical Genetics, 64(3), 190–197.PubMedCrossRef
Constantino, J. N., & Gruber, C. P. (2012). Social Responsiveness Scale (2nd ed.). Torrance, CA: Western Psychological Services.
Coutanche, M. N., Thompson-Schill, S. L., & Schultz, R. T. (2011). Multi-voxel pattern analysis of fMRI data predicts clinical symptom severity. Neuroimage, 57(1), 113–123.PubMedPubMedCentralCrossRef
Davis, J. M., Searles, V. B., Anderson, N., Keeney, J., Dumas, L., Sikela, J. M., & Foroud, T. (2014). DUF1220 Dosage is linearly associated with increasing severity of the three primary symptoms of autism. Plos Genetics, 10(3), 10:e1004241. doi:10.​1371/​journal.​pgen.​1004241.
Dereu, M., Roeyers, H., Raymaekers, R., Meirsschaut, M., & Warreyn, P. (2012). How useful are screening instruments for toddlers to predict outcome at age 4? General development, language skills, and symptom severity in children with a false positive screen for autism spectrum disorder. European Child and Adolescent Psychiatry, 21(10), 541–551.PubMedCrossRef
Di Rezze, B., Rosenbaum, P., & Zwaigenbaum, L. (2012). What attributes determine severity of function in autism? A web-based survey of stakeholders. Focus on Autism and Other Developmental Disabilities, 27(1), 39–41.CrossRef
Dickerson, A. S., Pearson, D. A., Loveland, K. A., Rahbar, M. H., & Filipek, P. A. (2014). Role of parental occupation in autism spectrum disorder diagnosis and severity. Research in Autism Spectrum Disorders, 8(9), 997–1007.PubMedPubMedCentralCrossRef
Doyle-Thomas, K. A. R., Kushki, A., Duerden, E. G., Taylor, M. J., Lerch, J. P., Soorya, L. V., & Anagnostou, E. (2013). The effect of diagnosis, age, and symptom severity on cortical surface area in the cingulate cortex and insula in autism spectrum disorders. Journal of Child Neurology, 28(6), 729–736.CrossRef
Eussen, M. L., Bruin, E. I., Gool, A. R., Louwerse, A., Ende, J., Verheij, F., et al. (2015). Formal thought disorder in autism spectrum disorder predicts future symptom severity, but not psychosis prodrome. European Child and Adolescent Psychiatry, 24(2), 163–172.PubMedCrossRef
Eussen, M. L. J. M., Van Gool, A. R., Verheij, F., De Nijs, P. F. A., Verhulst, F. C., & Greaves-Lord, K. (2013). The association of quality of social relations, symptom severity and intelligence with anxiety in children with autism spectrum disorders. Autism, 17(6), 723–735.PubMedCrossRef
Frazier, T. W., Youngstrom, E. A., Speer, L., Embacher, R., Law, P., Constantino, J., & Eng, C. (2012). Validation of proposed DSM-5 criteria for autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 51(1), 28–40.PubMedPubMedCentralCrossRef
Gadow, K. D., DeVincent, C. J., Olvet, D. M., Pisarevskaya, V., & Hatchwell, E. (2010). Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder. European Journal of Neuroscience, 32(6), 1058–1065.PubMedCrossRef
Geier, D. A., Hooker, B. S., Kern, J. K., Sykes, L. K., & Geier, M. R. (2014). An evaluation of the effect of increasing parental age on the phenotypic severity of autism spectrum disorder. Journal of Child Neurology, 1–6. doi:10.​1177/​0883073814541478​.
Geier, D. A., Kern, J. K., & Geier, M. R. (2009a). A prospective blinded evaluation of urinary porphyrins verses the clinical severity of autism spectrum disorders. Journal of Toxicology and Environmental Health. Part A, 72(24), 1585–1591.PubMedCrossRef
Geier, D. A., Kern, J. K., & Geier, M. R. (2009b). A prospective study of prenatal mercury exposure from maternal dental amalgams and autism severity. Acta Neurobiologiae Experimentalis, 69(2), 189–197.PubMed
Geier, D., Kern, J., King, P., Sykes, L., & Geier, M. (2012). Hair toxic metal concentrations and autism spectrum disorder severity in young children. International Journal of Environmental Research and Public Health, 9(12), 4486–4497.PubMedPubMedCentralCrossRef
Gibbard, C. R., Ren, J., Seunarine, K. K., Clayden, J. D., Skuse, D. H., & Clark, C. A. (2013). White matter microstructure correlates with autism trait severity in a combined clinical-control sample of high-functioning adults. Neuroimage Clinical, 3, 106–114.PubMedPubMedCentralCrossRef
Goldin, R. L., Matson, J. L., Beighley, J. S., & Jang, J. (2014). Autism spectrum disorder severity as a predictor of battelle developmental inventory—second edition (BDI-2) scores in toddlers. Developmental Neurorehabilitation, 17(1), 39–43.PubMedCrossRef
Gotham, K., Pickles, A., & Lord, C. (2009). Standardizing ADOS scores for a measure of severity in autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(5), 693–705.PubMedPubMedCentralCrossRef
Gotham, K., Pickles, A., & Lord, C. (2012). Trajectories of autism severity in children using standardized ADOS scores. Pediatrics, 130(5), e1278–e1284.PubMedPubMedCentralCrossRef
Hamza, R. T., Hewedi, D. H., & Sallam, M. T. (2013). Iodine deficiency in egyptian autistic children and their mothers: Relation to disease severity. Archives of Medical Research, 44(7), 555–561.PubMedCrossRef
Heine, S., Quackenbush, J., Lee, N., Frank, B., & Hu, V. (2006). Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes. BMC Genomics, 7(1), 1–18.CrossRef
Hilton, C. L., Harper, J. D., Kueker, R. H., Lang, A. R., Abbacchi, A. M., Todorov, A., & LaVesser, P. D. (2010). Sensory responsiveness as a predictor of social severity in children with high functioning autism spectrum disorders. Journal of Autism and Developmental Disorders, 40(8), 937–945.PubMedCrossRef
Hilton, C., Wente, L., LaVesser, P., Ito, M., Reed, C., & Herzberg, G. (2007). Relationship between motor skill impairment and severity in children with Asperger syndrome. Research in Autism Spectrum Disorders, 1(4), 339–349.CrossRef
Hock, R., & Ahmedani, B. K. (2012). Parent perceptions of autism severity: Exploring the social ecological context. Disability and Health Journal, 5(4), 298–304.PubMedCrossRef
Hollander, E., Soorya, L., Chaplin, W., Anagnostou, E., Taylor, B. P., Ferretti, C. J., & Settipani, C. (2012). A double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders. The American Journal of Psychiatry, 169(3), 292–299.PubMedCrossRef
Hrdlička, M., Komárek, V., Faladová, L., Zumrová, A., Beranová, I., Dudová, I., & Urbánek, T. (2004). EEG abnormalities are not associated with symptom severity in childhood autism. Studia Psychologica, 46(3), 229–234.
Hus, V., Gotham, K., & Lord, C. (2014). Standardizing ADOS domain scores: Separating severity of social affect and restricted and repetitive behaviors. Journal of Autism and Developmental Disorders, 44(10), 2400–2412.PubMedPubMedCentralCrossRef
Ingersoll, B., & Hambrick, D. Z. (2011). The relationship between the broader autism phenotype, child severity, and stress and depression in parents of children with autism spectrum disorders. Research in Autism Spectrum Disorders, 5(1), 337–344.CrossRef
Ismail, M., Hewedi, D., & Hamza, R. (2010). Basal and adrenocorticotropic hormone stimulated plasma cortisol levels among Egyptian autistic children: Relation to disease severity. Italian Journal of Pediatrics, 36(1), 1–6.CrossRef
Jang, J., Dixon, D. R., Tarbox, J., & Granpeesheh, D. (2011). Symptom severity and challenging behavior in children with ASD. Research in Autism Spectrum Disorders, 5(3), 1028–1032.CrossRef
Jiao, Y., Chen, R., Ke, X., Cheng, L., Chu, K., Lu, Z., & Herskovits, E. H. (2012). Single nucleotide polymorphisms predict symptom severity of autism spectrum disorder. Journal of Autism and Developmental Disorders, 42(6), 971–983.PubMedPubMedCentralCrossRef
Joseph, R. M., & Tager-Flusberg, H. (2004). The relationship of theory of mind and executive functions to symptom type and severity in children with autism. Development and Psychopathology, 16(1), 137–155.PubMedPubMedCentralCrossRef
Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217–250.
Keown, C. L., Shih, P., Nair, A., Peterson, N., Mulvey, M. E., & Müller, R. A. (2013). Local functional overconnectivity in posterior brain regions is associated with symptom severity in autism spectrum disorders. Cell Reports, 5(3), 567–572.PubMedCrossRef
Kern, J. K., Geier, D. A., Adams, J. B., Troutman, M. R., Davis, G., King, P. G., & Geier, M. R. (2011). Autism severity and muscle strength: A correlation analysis. Research in Autism Spectrum Disorders, 5(3), 1011–1015.CrossRef
Khakzad, M. R., Javanbakht, M., Shayegan, M. R., Kianoush, S., Omid, F., Hojati, M., & Meshkat, M. (2012). The complementary role of high sensitivity C-reactive protein in the diagnosis and severity assessment of autism. Research in Autism Spectrum Disorders, 6(3), 1032–1037.CrossRef
Kjellmer, L., Hedvall, Å., Fernell, E., Gillberg, C., & Norrelgen, F. (2012). Language and communication skills in preschool children with autism spectrum disorders: Contribution of cognition, severity of autism symptoms, and adaptive functioning to the variability. Research in Developmental Disabilities, 33(1), 172–180.PubMedCrossRef
Konstantareas, M. M., & Papageorgiou, V. (2006). Effects of temperament, symptom severity and level of functioning on maternal stress in Greek children and youth with ASD. Autism : the International Journal of Research and Practice, 10(6), 593–607.CrossRef
Le Couteur, A., Lord, C., and Rutter, M. (2003). Autism diagnostic interview-revised (ADI-R) Los Angeles: Western Psychological Services.
Lin, J.-D., Sung, C.-L., Lin, L.-P., Hsu, S.-W., Chien, W.-C., Su, S.-L., & Wu, J.-L. (2011). Ten-year trend analysis of autism severity: A nationwide population-based register study. Research in Autism Spectrum Disorders, 5(1), 570–574.CrossRef
Llewellyn, G., Riches, V. C., Hindmarsh, G. J., Parmenter, T. R., & Chan, J. (2005). I-CAN: Instrument to classify support needs for people with disability. Sydney: The Faculty of Health Sciences.
Lord, C., Rutter, M., DiLavore, P. C., Risi, S., Gotham, K., & Bishop, S. (2012). Autism diagnostic observation schedule (2nd ed.). Torrance, CA: Western Psychological Services.
MacDonald, M., Lord, C., & Ulrich, D. A. (2014). Motor skills and calibrated autism severity in young children with autism spectrum disorder. Adapted Physical Activity Quarterly, 31(2), 95–105.PubMedCrossRef
Mandy, W. P. L., Charman, T., & Skuse, D. H. (2012). Testing the construct validity of proposed criteria for DSM-5 autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 51(1), 41–50.PubMedCrossRef
Matson, J. L., & Goldin, R. L. (2014). What is the future of assessment for autism spectrum disorders: Short and long term. Research in Autism Spectrum Disorders, 8(3), 209–213.CrossRef
Matson, J. L., & Rivet, T. T. (2008). The effects of severity of autism and PDD-NOS symptoms on challenging behaviors in adults with intellectual disabilities. Journal of Developmental and Physical Disabilities, 20(1), 41–51.CrossRef
Matson, J. L., Wilkins, J., & Macken, J. (2009). The relationship of challenging behaviors to severity and symptoms of autism spectrum disorders. Journal of Mental Health Research in Intellectual Disabilities, 2(1), 29–44.CrossRef
Matson, J. L., Worley, J. A., Neal, D., Mahan, S., & Fodstad, J. C. (2010). The effects of inattention/impulsivity and ASD symptom severity on social skills in toddlers. Developmental Neurorehabilitation, 13(6), 408–412.
McStay, R. L., Dissanayake, C., Scheeren, A., Koot, H. M., & Begeer, S. (2014). Parenting stress and autism: The role of age, autism severity, quality of life and problem behaviour of children and adolescents with autism. Autism, 18(5), 502–510.PubMedCrossRef
Meresse, I. G., Zilbovicius, M., Boddaert, N., Robel, L., Philippe, A., Sfaello, I., & Chabane, N. (2005). Autism severity and temporal lobe functional abnormalities. Annals of Neurology, 58(3), 466–469.CrossRef
Mostafa, G. A., & AL-ayadhi, L. Y. (2011). Increased serum levels of anti-ganglioside M1 auto-antibodies in autistic children: relation to the disease severity. Journal of Neuroinflammation, 8(1), 39–44.
Mostafa, G. A., & Al-Ayadhi, L. Y. (2012). The relationship between the increased frequency of serum antineuronal antibodies and the severity of autism in children. European Journal of Paediatric Neurology: Ejpn: Official Journal of the European Paediatric Neurology Society, 16(5), 464–468.CrossRef
Movsas, T. Z., & Paneth, N. (2012). The effect of gestational age on symptom severity in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 42(11), 2431–2439.PubMedCrossRef
Nagar, S. H., Weizman, A., Yoran, R. H., & Raviv, A. (2012). Theory of mind, severity of autistic symptoms and parental correlates in children and adolescents with Asperger syndrome. Psychiatry Research, 197, 1–2.CrossRef
Nicholas, J. S., Charles, J. M., Carpenter, L. A., King, L. B., Jenner, W., & Sprat, E. G. (2008). Prevalence and characteristics of children with autism-spectrum disorders. Annals of Epidemiology, 18, 130–136.PubMedCrossRef
Parks, L. K., Hill, D. E., Thoma, R. J., Euler, M. J., Lewine, J. D., & Yeo, R. A. (2009). Neural correlates of communication skill and symptom severity in Autism: A voxel-based morphometry study. Research in Autism Spectrum Disorders, 3(2), 444–454.CrossRef
Poustka, L., Jennen-Steinmetz, C., Henze, R., Vomstein, K., Haffner, J., & Sieltjes, B. (2012). Fronto-temporal disconnectivity and symptom severity in children with autism spectrum disorder. The World Journal of Biological Psychiatry, 13(4), 269–280.PubMedCrossRef
Pry, R., Guillain, A., Aussilloux, C., & Baghdadli, A. (2004). Severity of the autistic disorder and organization of socio-cognitive skills: Differentiation or dissociation. European Review of Applied Psychology/Revue Européenne de Psychologie Appliquée, 54(3), 157–163.CrossRef
Rao, P. A., & Landa, R. J. (2014). Association between severity of behavioral phenotype and comorbid attention deficit hyperactivity disorder symptoms in children with autism spectrum disorders. Autism, 18(3), 272–280.PubMedPubMedCentralCrossRef
Robinson, E. B., Samocha, K. E., Kosmicki, J. A., McGrath, L., Neale, B. M., Perlis, R. H., & Daly, M. J. (2014). Autism spectrum disorder severity reflects the average contribution of de novo and familial influences. PNAS Proceedings of the National Academy of Sciences of the United States of America, 111(42), 15161–15165.CrossRef
Russo, A. (2014a). Decreased mitogen inducible gene 6 (MIG-6) associated with symptom severity in children with autism. Biomarker Insights, 9, 85–89.PubMedPubMedCentralCrossRef
Russo, A. J. (2014b). Increased epidermal growth factor receptor (EGFR) associated with hepatocyte growth factor (HGF) and symptom severity in children with autism spectrum disorders (ASDs). Journal of Central Nervous System Disease, 6, 79–83.PubMedPubMedCentralCrossRef
Russo, A. J., Bazin, A. P., Bigega, R., Carlson, R. S., Cole, M. G., Contreras, D. C., et al. (2012). Plasma copper and zinc concentration in individuals with autism correlate with selected symptom severity. Nutrition and Metabolic Insights, 5, 41–47.PubMedPubMedCentralCrossRef
Rutter, M. L. (2011). Progress in understanding autism: 2007-2010. Journal of Autism and Developmental Disabilities, 41, 395–404.CrossRef
Schopler, E., Van Bourgondien, M., Wellman, G., & Love, S. (2010). Childhood Autism Rating Scale (2nd ed.). Los Angeles, CA: Western Psychological Services.
Schumann, C. M., Barnes, C. C., Lord, C., & Courchesne, E. (2009). Amygdala enlargement in toddlers with autism related to severity of social and communication impairments. Biological Psychiatry, 66(10), 942–949.PubMedPubMedCentralCrossRef
South, M., Larson, M. J., White, S. E., Dana, J., & Crowley, M. J. (2011). Better fear conditioning is associated with reduced symptom severity in autism spectrum disorders. Autism Research, 4(6), 412–421.PubMedCrossRef
Sparrow, S. S., Balla, D. A., Cicchetti, D. V., Doll, E. A., & American Guidance Service. (2005). Vineland adaptive behavior scales (2nd ed.). Bloomington, MN: NCS Pearson.
Spiker, D., Lotspeich, L. J., Dimiceli, S., Myers, R. M., & Risch, N. (2002). Behavioral phenotypic variation in autism multiplex families: Evidence for a continuous severity gradient. American Journal of Medical Genetics, 114(2), 129–136.PubMedCrossRef
Sprenger, L., Bühler, E., Poustka, L., Bach, C., Heinzel-Gutenbrunner, M., Kamp-Becker, I., & Bachmann, C. (2013). Impact of ADHD symptoms on autism spectrum disorder symptom severity. Research in Developmental Disabilities, 34(10), 3545–3552.PubMedCrossRef
Thompson, J. R., Bryant, B. L., Campbell, E. M., Craig, E. M., Hughes, C. M., Rotholz, D. A., & Wehmeyer, M. L. (2004). Supports intensity scale. Washington, DC: American Association on Intellectual and Developmental Disabilities.
Thompson, J., Hughes, C., Schalock, R., Silverman, W., Tassé, M. J., Bryant, B., et al. (2002). Integrating supports into assessment and planning. Mental Retardation, 40, 390–405.PubMedCrossRef
Thurm, A., Manwaring, S. S., Swineford, L., & Farmer, C. (2015). Longitudinal study of symptom severity and language in minimally verbal children with autism. Journal of Child Psychology and Psychiatry, 56(1), 97–104.PubMedPubMedCentralCrossRef
Travers, B. G., Powell, P. S., Klinger, L. G., & Klinger, M. R. (2013). Motor difficulties in autism spectrum disorder: Linking symptom severity and postural stability. Journal of Autism and Developmental Disorders, 43(7), 1568–1583.PubMedCrossRef
Tsatsanis, K. D., Dartnall, N., Cicchetti, D., Sparrow, S. S., Klin, A., & Volkmar, F. R. (2003). Concurrent validity and classification accuracy of the Leiter and Leiter-R in low-functioning children with autism. Journal of Autism and Developmental Disorders, 33, 23–30.PubMedCrossRef
Tudor, M. E., Hoffman, C. D., & Sweeney, D. P. (2012). Children with autism: Sleep problems and symptom severity. Focus on Autism and Other Developmental Disabilities, 27(4), 254–262.CrossRef
Tureck, K., Matson, J. L., Cervantes, P., & Turygin, N. (2015). Autism severity as a predictor of inattention and impulsivity in toddlers. Developmental Neurorehabilitation, 18, 285–289.
Uddin, L. Q., Supekar, K., Lynch, C. J., Khouzam, A., Phillips, J., Feinstein, C., & Menon, V. (2013). Salience network–based classification and prediction of symptom severity in children with autism. JAMA Psychiatry, 70(8), 869–879.PubMedPubMedCentralCrossRef
Venker, C. E., Ray-Subramanian, C. E., Bolt, D. M., & Weismer, S. E. (2014). Trajectories of autism severity in early childhood. Journal of Autism and Developmental Disorders, 44(3), 546–563.PubMedPubMedCentralCrossRef
Wallace, A. E., Anderson, G. M., & Dubrow, R. (2008). Obstetric and parental psychiatric variables as potential predictors of autism severity. Journal of Autism and Developmental Disorders, 38(8), 1542–1554.PubMedCrossRef
Weil, T. N. & Inglehart, M. R. (2012). Three- to 21-year-old patients with autism spectrum disorders: parents’ perceptions of severity of symptoms, oral health, and oral health-related behavior. Pediatric Dentistry, 34(7), 473–479.
Weitlauf, A. S., Gotham, K. O., Vehorn, A. C., & Warren, Z. E. (2014). Brief report: DSM-5 “levels of support:” A comment on discrepant conceptualizations of severity in ASD. Journal of Autism and Developmental Disorders, 44(2), 471–476.PubMedPubMedCentralCrossRef
Wells, K., Condillac, R., Perry, A., & Factor, D. C. (2009). A comparison of three adaptive behaviour measures in relation to cognitive level and severity of autism. Journal on Developmental Disabilities, 15(3), 55–63.
White, S. W., Schry, A. R., Miyazaki, Y., Ollendick, T. H., & Scahill, L. (2015). Effects of verbal ability and severity of autism on anxiety in adolescents with ASD: One-year follow-up after cognitive behavioral therapy. Journal of Clinical Child and Adolescent Psychology, 44, 839–845.
Williams, B. T., & Gray, K. M. (2013). Are emotion recognition skills related to autism symptom severity in children with autism? International Journal of Developmental Disabilities, 59(2), 118–133.CrossRef
Wisessathorn, M., Chanuantong, T., & Fisher, E. B. (2013). The impact of child’s severity on quality-of-life among parents of children with autism spectrum disorder: the mediating role of optimism. Journal of the Medical Association of Thailand Chotmaihet Thangphaet, 96(10), 1313–1318.PubMed
Wood, J. J., Fujii, C., Renno, P., & Dyke, M. (2014). Impact of cognitive behavioral therapy on observed autism symptom severity during school recess: A preliminary randomized, controlled trial. Journal of Autism and Developmental Disorders, 44(9), 2264–2276.PubMed
Zachor, D. A., Ilanit, T., & Itzchak, E. B. (2010). Autism severity and motor abilities correlates of imitation situations in children with autism spectrum disorders. Research in Autism Spectrum Disorders, 4(3), 438–443.CrossRef
Metagegevens
Titel
Severity of Autism Spectrum Disorders: Current Conceptualization, and Transition to DSM-5
Auteurs
Margaret H. Mehling
Marc J. Tassé
Publicatiedatum
12-02-2016
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 6/2016
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-016-2731-7

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