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We report on a 44-year-old woman presenting with chest pain and dyspnoea without previous stress-related events. By means of echocardiography severe left ventricular dysfunction and wall motion abnormalities resembling stress-induced cardiomyopathy (Tako Tsubo) were seen. Laboratory investigation revealed thyrotoxicosis and elevated cardiac markers. Six days after starting medical treatment, complete restoration of the left ventricular function was observed. The transient left ventricular dysfunction was induced by thyrotoxicosis resembling stress-induced cardiomyopathy that resolved completely after medical treatment.
Lyon AR, Rees PSC, Prasad S, et al. Stress (TakoTsubo) cardiomyopathy—a novel pathophysiological hypothesis to explain catecholamine induced acute myocardial stunning. Nat Clin Pract. 2008;5(1):22–9.
Froeschl M, Haddad H, Commons AS, et al. Thyrotoxicosis-an uncommon cause of heart failure. Cardiovas Pathol. 2005;14:24–7. CrossRef
Ojamaa K, Samarel A, Kupfer T, et al. Thyroid hormone effects on cardiac gene expression independent of cardiac growth and protein synthesis. Am J Physiol. 1992;263:E534–40. PubMed
- Severe transient left ventricular dysfunction induced by thyrotoxicosis
- Bohn Stafleu van Loghum