Skip to main content
Top
Gepubliceerd in:

06-06-2017 | Original Paper

Screening of Autism Spectrum Disorders in Geriatric Psychiatry

Auteurs: S. M. J. Heijnen-Kohl, R. M. Kok, R. M. H. J. Wilting, G. Rossi, S. P. J. van Alphen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2017

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Autism spectrum disorders (ASD) are difficult to detect in old age. This study examined if ASD symptoms in older adults (age > 60) can be detected with the Dutch informant personality questionnaire, (Hetero-Anamnestische Persoonlijkheidsvragenlijst, HAP) in a mental health setting. Patients with ASD (N = 40) were compared to patients with a different psychiatric diagnosis (N = 43; personality disorders excluded). The ASD group had significant higher scores on the scales ‘Socially avoidant behavior’, ‘Rigid behavior’ and ‘Unpredictable and impulsive behavior’. These scales were able to discriminate between individuals with or without ASD. The HAP can thus be used as a screening instrument for ASD symptoms in elderly patients. Further research is needed to clarify what items have the best predictive validity for ASD symptoms.
Voetnoten
1
Kurtosis was within range (z < 2) for both groups on all scales. Skewness was within range (z < 2) for the scales ‘perfectionist behavior’ and ‘antagonistic behavior’. Skewness was outside range (z > 2) on the scale ‘somatizing behavior’ for both groups. On the other scales, skewness was outside range (z > 2) for either the ASD or the psychiatric control group. Therefore the results of the t test for these scales are double checked non-parametricly with a Mann–Withney test, which led to the same results.
 
Literatuur
go back to reference Agresti, A. (1996). An introduction to categorical data analysis (2nd edn.). New York: Wiley. Agresti, A. (1996). An introduction to categorical data analysis (2nd edn.). New York: Wiley.
go back to reference American Psychiatric Association (Ed.). (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR®. Washington, DC: American Psychiatric Publishing. American Psychiatric Association (Ed.). (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR®. Washington, DC: American Psychiatric Publishing.
go back to reference American Psychiatric Association (Ed.). (2013). Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5™). American Psychiatric Pub. American Psychiatric Association (Ed.). (2013). Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5™). American Psychiatric Pub.
go back to reference American Psychological Association (2004). Guidelines for psychological practice with older adults. American Psychologist, 59(4), 236–260.CrossRef American Psychological Association (2004). Guidelines for psychological practice with older adults. American Psychologist, 59(4), 236–260.CrossRef
go back to reference Barendse, H. P. J., & Thissen, A. J. C. (2006). Handleiding van de Hetero-Anamnestische Persoonlijkheidsvragenlijst HAP. Barendse & Thissen. Barendse, H. P. J., & Thissen, A. J. C. (2006). Handleiding van de Hetero-Anamnestische Persoonlijkheidsvragenlijst HAP. Barendse & Thissen.
go back to reference Barendse, H. P. J., Thissen, A. J. C., Rossi, G., Oei, T. I., & Van Alphen, S. P. J. (2013). Psychometric properties of an informant personality questionnaire (the HAP) in a sample of older adults in the Netherlands and Belgium. Aging & Mental Health, 17(5), 623–629.CrossRef Barendse, H. P. J., Thissen, A. J. C., Rossi, G., Oei, T. I., & Van Alphen, S. P. J. (2013). Psychometric properties of an informant personality questionnaire (the HAP) in a sample of older adults in the Netherlands and Belgium. Aging & Mental Health, 17(5), 623–629.CrossRef
go back to reference Barneveld, P. S., Pieterse, J., de Sonneville, L., van Rijn, S., Lahuis, B., van Engeland, H., & Swaab, H. (2011). Overlap of autistic and schizotypal traits in adolescents with autism spectrum disorders. Schizophrenia Research, 126(1), 231–236.CrossRefPubMed Barneveld, P. S., Pieterse, J., de Sonneville, L., van Rijn, S., Lahuis, B., van Engeland, H., & Swaab, H. (2011). Overlap of autistic and schizotypal traits in adolescents with autism spectrum disorders. Schizophrenia Research, 126(1), 231–236.CrossRefPubMed
go back to reference Baxter, A. J., Brugha, T. S., Erskine, H. E., Scheurer, R. W., Vos, T., & Scott, J. G. (2015). The epidemiology and global burden of autism spectrum disorders. Psychological Medicine, 45(03), 601–613.CrossRefPubMed Baxter, A. J., Brugha, T. S., Erskine, H. E., Scheurer, R. W., Vos, T., & Scott, J. G. (2015). The epidemiology and global burden of autism spectrum disorders. Psychological Medicine, 45(03), 601–613.CrossRefPubMed
go back to reference Bejerot, S. (2007). An autistic dimension A proposed subtype of obsessive-compulsive disorder. AUTISM: The International Journal of Research and Practice, 11(2), 101–110.CrossRef Bejerot, S. (2007). An autistic dimension A proposed subtype of obsessive-compulsive disorder. AUTISM: The International Journal of Research and Practice, 11(2), 101–110.CrossRef
go back to reference Billstedt, E. (2000). Autism and Asperger syndrome: Coexistence with other clinical disorders. Acta Psychiatrica Scandinavica, 102(5), 321–330.CrossRefPubMed Billstedt, E. (2000). Autism and Asperger syndrome: Coexistence with other clinical disorders. Acta Psychiatrica Scandinavica, 102(5), 321–330.CrossRefPubMed
go back to reference Billstedt, E., Carina Gillberg, I., & Gillberg, C. (2007). Autism in adults: Symptom patterns and early childhood predictors. Use of the DISCO in a community sample followed from childhood. Journal of Child Psychology and Psychiatry, 48(11), 1102–1110.CrossRefPubMed Billstedt, E., Carina Gillberg, I., & Gillberg, C. (2007). Autism in adults: Symptom patterns and early childhood predictors. Use of the DISCO in a community sample followed from childhood. Journal of Child Psychology and Psychiatry, 48(11), 1102–1110.CrossRefPubMed
go back to reference Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillside, NJ: Lawrence Earlbaum Associates. Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillside, NJ: Lawrence Earlbaum Associates.
go back to reference De Koning, M. B., & Fouwels, A. J. (2005). Stoornis van Asperger of persoonlijkheidsstoornis uit het A-cluster: Differentiële diagnostiek bij een volwassen patiënt. Tijdschrift voor Psychiatrie, 47(10), 707. De Koning, M. B., & Fouwels, A. J. (2005). Stoornis van Asperger of persoonlijkheidsstoornis uit het A-cluster: Differentiële diagnostiek bij een volwassen patiënt. Tijdschrift voor Psychiatrie, 47(10), 707.
go back to reference Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39, 175–191.CrossRefPubMed Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39, 175–191.CrossRefPubMed
go back to reference Geurts, H. M., & Vissers, M. E. (2012). Elderly with autism: Executive functions and memory. Journal of Autism and DevelopmentalDisorders, 42, 665–675.CrossRef Geurts, H. M., & Vissers, M. E. (2012). Elderly with autism: Executive functions and memory. Journal of Autism and DevelopmentalDisorders, 42, 665–675.CrossRef
go back to reference Happé, F. (2011). Criteria, categories, and continua: Autism and related disorders in DSM-5. Journal of the American Academy of Child & Adolescent Psychiatry, 50(6), 540–542.CrossRef Happé, F. (2011). Criteria, categories, and continua: Autism and related disorders in DSM-5. Journal of the American Academy of Child & Adolescent Psychiatry, 50(6), 540–542.CrossRef
go back to reference Happé, F., & Charlton, R. A. (2012). Aging in autism spectrum disorders: A mini-review. Gerontology, 58, 70–78.CrossRefPubMed Happé, F., & Charlton, R. A. (2012). Aging in autism spectrum disorders: A mini-review. Gerontology, 58, 70–78.CrossRefPubMed
go back to reference Heijnen-Kohl, S.M.J., & van Alphen S.P.J. (2009). Diagnostiek van autismespectrumstoornissen bij ouderen. Tijdschrift voor psychiatrie;, 51(5), 1–5. Heijnen-Kohl, S.M.J., & van Alphen S.P.J. (2009). Diagnostiek van autismespectrumstoornissen bij ouderen. Tijdschrift voor psychiatrie;, 51(5), 1–5.
go back to reference Heijnen-Kohl, S.M.J., Van Alphen, S.P.J., & Oude Voshaar, R. C. (2016). Issues in diagnosis and assessment in later life. Chapter 10. In S. D. Wright (Ed.), Autism spectrum disorders in mid and later life (pp. 163–176). London: Jessica Kingsley. Heijnen-Kohl, S.M.J., Van Alphen, S.P.J., & Oude Voshaar, R. C. (2016). Issues in diagnosis and assessment in later life. Chapter 10. In S. D. Wright (Ed.), Autism spectrum disorders in mid and later life (pp. 163–176). London: Jessica Kingsley.
go back to reference Hengeveld, M. W., Van Londen, L., & van de Gaag, R. J. (2008). Herkenning van autismespectrumstoornissen bij volwassenen. Nederlands tijdschrift voor geneeskunde, 152(24), 1353–1357.PubMed Hengeveld, M. W., Van Londen, L., & van de Gaag, R. J. (2008). Herkenning van autismespectrumstoornissen bij volwassenen. Nederlands tijdschrift voor geneeskunde, 152(24), 1353–1357.PubMed
go back to reference Hrdlicka, M, & Dudova I. (2013). Controversies in autism: Is a broader model of social disorders needed? Child Adolescent Psychiatry and Mental Health, 18, 7(1), 7–9. Hrdlicka, M, & Dudova I. (2013). Controversies in autism: Is a broader model of social disorders needed? Child Adolescent Psychiatry and Mental Health, 18, 7(1), 7–9.
go back to reference Hurst, R. M., Nelson-Gray, R. O., Mitchell, J. T., & Kwapil, T. R. (2007). The relationship of Asperger’s characteristics and schizotypal personality traits in a non-clinical adult sample. Journal of Autism and Developmental Disorders, 37(9), 1711–1720.CrossRefPubMed Hurst, R. M., Nelson-Gray, R. O., Mitchell, J. T., & Kwapil, T. R. (2007). The relationship of Asperger’s characteristics and schizotypal personality traits in a non-clinical adult sample. Journal of Autism and Developmental Disorders, 37(9), 1711–1720.CrossRefPubMed
go back to reference James, I. A., Mukaetova-Ladinska, E., Reichelt, F. K., Briel, R., & Scully, A. (2006). Diagnosing aspergers syndrome in the elderly: A series of case presentations. International Journal of Geriatric Psychiatry, 21, 951–960.CrossRefPubMed James, I. A., Mukaetova-Ladinska, E., Reichelt, F. K., Briel, R., & Scully, A. (2006). Diagnosing aspergers syndrome in the elderly: A series of case presentations. International Journal of Geriatric Psychiatry, 21, 951–960.CrossRefPubMed
go back to reference Klonsky, E. D., & Oltmanns, T. F. (2002). Informant-reports of personality disorder: Relation to self-reports and future research directions. Clinical Psychology: Science and Practice, 9(3), 300–311. Klonsky, E. D., & Oltmanns, T. F. (2002). Informant-reports of personality disorder: Relation to self-reports and future research directions. Clinical Psychology: Science and Practice, 9(3), 300–311.
go back to reference Kok, E., & Eurelings-Bontekoe, E. H. M. (2007). De Nederlandse Verkorte MMPI en Austisme Spectrum Stoornis [The Dutch Short Form of the MMPI and Autism Spectrum Disorder]. Wetenschappelijk Tijdschrift Autisme, 1, 32–40. Kok, E., & Eurelings-Bontekoe, E. H. M. (2007). De Nederlandse Verkorte MMPI en Austisme Spectrum Stoornis [The Dutch Short Form of the MMPI and Autism Spectrum Disorder]. Wetenschappelijk Tijdschrift Autisme, 1, 32–40.
go back to reference Lever, A. G. (2016). Aging in Autism: Symptomatology, co-occurring psychopathology, and cognitive functioning across the adult life-span. Amsterdam. Lever, A. G. (2016). Aging in Autism: Symptomatology, co-occurring psychopathology, and cognitive functioning across the adult life-span. Amsterdam.
go back to reference Levy, A., & Perry, A. (2011). Outcomes in adolescents and adults with autism: A review of the literature. Research in Autism Spectrum Disorders, 5(4), 1271–1282.CrossRef Levy, A., & Perry, A. (2011). Outcomes in adolescents and adults with autism: A review of the literature. Research in Autism Spectrum Disorders, 5(4), 1271–1282.CrossRef
go back to reference Lugnegård, T., Hallerbäck, M. U., & Gillberg, C. (2012). Personality disorders and autism spectrum disorders: What are the connections? Comprehensive Psychiatry, 53(4), 333–340.CrossRefPubMed Lugnegård, T., Hallerbäck, M. U., & Gillberg, C. (2012). Personality disorders and autism spectrum disorders: What are the connections? Comprehensive Psychiatry, 53(4), 333–340.CrossRefPubMed
go back to reference Matilla, M. L., Hurtig, T., Haapsamo, H., Jussila, K., Kuusikko-Gauffin, S., Kielinen, M., ... Moilanen, I. (2010). Comorbid psychiatric disorders associated with Asperger syndrome/high-functioning autism: A community-and clinic-based study. Journal of Autism and Developmental Disorders, 40(9), 1080–1093.CrossRef Matilla, M. L., Hurtig, T., Haapsamo, H., Jussila, K., Kuusikko-Gauffin, S., Kielinen, M., ... Moilanen, I. (2010). Comorbid psychiatric disorders associated with Asperger syndrome/high-functioning autism: A community-and clinic-based study. Journal of Autism and Developmental Disorders, 40(9), 1080–1093.CrossRef
go back to reference Mukaetova-Ladinska, E. B., Perry, E., Baron, M., & Povey, C. (2012). Ageing in people with autistic spectrum disorders. International Journal of Geriatric Psychiatry, 27, 109–118.CrossRefPubMed Mukaetova-Ladinska, E. B., Perry, E., Baron, M., & Povey, C. (2012). Ageing in people with autistic spectrum disorders. International Journal of Geriatric Psychiatry, 27, 109–118.CrossRefPubMed
go back to reference Naidu, A., James, I., Mukatoeva-Ladinska, E., & Briel, R. (2006). Diagnosis of asperger syndrome in a 66-year-old male presenting with depression. International Psychogeriatrics, 18(1), 171–188.CrossRefPubMed Naidu, A., James, I., Mukatoeva-Ladinska, E., & Briel, R. (2006). Diagnosis of asperger syndrome in a 66-year-old male presenting with depression. International Psychogeriatrics, 18(1), 171–188.CrossRefPubMed
go back to reference Nylander, L., Lugnegård, T., & Hallerbäck, M. (2008). Autism spectrum disorders and schizophrenia spectrum disorders in adults—Is there a connection? A literature review and some suggestions for future clinical research. Clinical Neuropsychiatry, 5(1), 43–54. Nylander, L., Lugnegård, T., & Hallerbäck, M. (2008). Autism spectrum disorders and schizophrenia spectrum disorders in adults—Is there a connection? A literature review and some suggestions for future clinical research. Clinical Neuropsychiatry, 5(1), 43–54.
go back to reference Ozonoff, S., Garcia, N., Clark, E., & Lainhart, J. E. (2005). MMPI-2 personality profiles of high-functioning adults with autism spectrum disorders. Assessment, 12(1), 86–95.CrossRefPubMed Ozonoff, S., Garcia, N., Clark, E., & Lainhart, J. E. (2005). MMPI-2 personality profiles of high-functioning adults with autism spectrum disorders. Assessment, 12(1), 86–95.CrossRefPubMed
go back to reference Perkins, E. A., & Berkman, K. A. (2012). Into the unknown: Aging with autism spectrum disorders. American Journal on Intellectual and Developmental Disabilities, 117(6), 478–496.CrossRefPubMed Perkins, E. A., & Berkman, K. A. (2012). Into the unknown: Aging with autism spectrum disorders. American Journal on Intellectual and Developmental Disabilities, 117(6), 478–496.CrossRefPubMed
go back to reference Piven, J., & Rabins, P. (2011). Autism spectrum disorders in older adults: Towards defining a research agenda. Journal of American Geriatrics Society, 59, 2151–2155.CrossRef Piven, J., & Rabins, P. (2011). Autism spectrum disorders in older adults: Towards defining a research agenda. Journal of American Geriatrics Society, 59, 2151–2155.CrossRef
go back to reference Seltzer, M. M., Shattuck, P., Abbeduto, L., & Greenberg, J. S. (2004). Trajectory of development in adolescents and adults with autism. Mental Retardation and Developmental Disabilities Research Reviews, 10(4), 234–247.CrossRefPubMed Seltzer, M. M., Shattuck, P., Abbeduto, L., & Greenberg, J. S. (2004). Trajectory of development in adolescents and adults with autism. Mental Retardation and Developmental Disabilities Research Reviews, 10(4), 234–247.CrossRefPubMed
go back to reference Soderstrom, H., Rastam, M., & Gillberg, C. (2002). Temperament and character in adults with Asperger syndrome. Autism: The International Journal of Research and Practice, 6(3), 287–297.CrossRef Soderstrom, H., Rastam, M., & Gillberg, C. (2002). Temperament and character in adults with Asperger syndrome. Autism: The International Journal of Research and Practice, 6(3), 287–297.CrossRef
go back to reference Spek, A.A, & Geven, F. (2013). Autismespectrumstoornissen bij Ouderen. De Psycholoog, 48(7/8), 53–60. Spek, A.A, & Geven, F. (2013). Autismespectrumstoornissen bij Ouderen. De Psycholoog, 48(7/8), 53–60.
go back to reference Totsika, V., Felce, D., Kerr, M., & Hastings, R. P. (2010). Behavioural problems, psychiatric symptoms, and quality of life for older adults with intellectual disability with and without autism. Journal of Autism Developmental Disorders, 40, 1171–1178.CrossRefPubMed Totsika, V., Felce, D., Kerr, M., & Hastings, R. P. (2010). Behavioural problems, psychiatric symptoms, and quality of life for older adults with intellectual disability with and without autism. Journal of Autism Developmental Disorders, 40, 1171–1178.CrossRefPubMed
go back to reference Van Alphen, S.P.J., & Heijnen-Kohl, S.M.J. (2009). Gevalsbeschrijving over een 82-jarige man met een Autismespectrumstoornis. GZ-Psychologie, 2, 1–10. Van Alphen, S.P.J., & Heijnen-Kohl, S.M.J. (2009). Gevalsbeschrijving over een 82-jarige man met een Autismespectrumstoornis. GZ-Psychologie, 2, 1–10.
go back to reference Van Alphen, S.P.J., & Oude Voshaar, R. C. (2012). Screening of autism spectrum disorders in the elderly. A contribution to a psychometric approach. International Psychogeriatrics, 24, 1187–1188.CrossRefPubMed Van Alphen, S.P.J., & Oude Voshaar, R. C. (2012). Screening of autism spectrum disorders in the elderly. A contribution to a psychometric approach. International Psychogeriatrics, 24, 1187–1188.CrossRefPubMed
go back to reference Van Niekerk, M.E.H., Groen, W., Vissers, C.W.M., van Driel-de Jong, D., Kan, C. C., & Oude Voshaar, R. C. (2010). Diagnosing autism spectrum disorders in elderly people. International Psychogeriatrics, 29, 1–11. Van Niekerk, M.E.H., Groen, W., Vissers, C.W.M., van Driel-de Jong, D., Kan, C. C., & Oude Voshaar, R. C. (2010). Diagnosing autism spectrum disorders in elderly people. International Psychogeriatrics, 29, 1–11.
go back to reference Verbeek, M., Knispel, A., & Nuijen, J. (2012). GGZ in tabellen 2011. Trimbos-instituut. Verbeek, M., Knispel, A., & Nuijen, J. (2012). GGZ in tabellen 2011. Trimbos-instituut.
go back to reference Vuijk, R., de Nijs, P.F.A., Vitale, S. G., Simons-Sprong, M., & Hengeveld, M. W. (2012). Persoonlijkheidsaspecten bij volwassenen met autismespectrumstoornissen gemeten met de ‘Temperament and Character Inventory’ (TCI). Tijdschrift voor psychiatrie, 54(8), 699–707.PubMed Vuijk, R., de Nijs, P.F.A., Vitale, S. G., Simons-Sprong, M., & Hengeveld, M. W. (2012). Persoonlijkheidsaspecten bij volwassenen met autismespectrumstoornissen gemeten met de ‘Temperament and Character Inventory’ (TCI). Tijdschrift voor psychiatrie, 54(8), 699–707.PubMed
go back to reference Wright, S. D. (Ed.). (2016). Autism spectrum disorders in mid and later life. London: Jessica Kingsley. Wright, S. D. (Ed.). (2016). Autism spectrum disorders in mid and later life. London: Jessica Kingsley.
Metagegevens
Titel
Screening of Autism Spectrum Disorders in Geriatric Psychiatry
Auteurs
S. M. J. Heijnen-Kohl
R. M. Kok
R. M. H. J. Wilting
G. Rossi
S. P. J. van Alphen
Publicatiedatum
06-06-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 9/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-017-3185-2