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04-04-2024

Risk factors and intervention of caregiver burden in Parkinson’s disease: a systematic review and meta-analysis

Auteurs: Yan Zhao, Wenxiang Wu, Jianjun Wu, Bin Shen, Yanpei Cao, Yafang Xu

Gepubliceerd in: Quality of Life Research | Uitgave 7/2024

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Abstract

Purpose

This study summarized characteristics and risk factors of caregiver burden in PD patients and used meta-analysis to verify the effectiveness of the intervention on caregiver burden.

Methods

Systematic review and meta-analysis were conducted.

Results

Forty-nine articles that involved 5387 caregivers of patients with PD were included in this study. Results of systematic review indicated that Zarit burden Inventory (ZBI) was the most used scale to measure the caregiver burden. All scales revealed caregivers of PD patients had mild to moderate caregiver burden. For the PD patients with longer disease duration, severer disease severity, more negative emotion and cognition impairment, their caregivers intended to have higher caregiver burden. The caregiver with negative emotion and who spent more time on caregiving indicated higher caregiver burden than the others. The caregiver burden was not improved after deep brain stimulation (DBS). Meta-analysis showed that cognitive behavior therapy and palliative care had no significant effect to reduce caregiver burden in PD patients’ caregiver.

Conclusion

Caregivers of PD patients experienced mild to moderate caregiver burden. Demographic factor, diseased-related factor and negative emotional factor were the risk factors of caregiver burden. Health education and care support for long-term management after DBS surgery should be provided for patients and caregivers to decrease caregiver burden.
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Metagegevens
Titel
Risk factors and intervention of caregiver burden in Parkinson’s disease: a systematic review and meta-analysis
Auteurs
Yan Zhao
Wenxiang Wu
Jianjun Wu
Bin Shen
Yanpei Cao
Yafang Xu
Publicatiedatum
04-04-2024
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 7/2024
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-024-03616-0