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01-06-2014 | Original Paper | Uitgave 6/2014

Journal of Autism and Developmental Disorders 6/2014

Rigid–Compulsive Behaviors are Associated with Mixed Bowel Symptoms in Autism Spectrum Disorder

Tijdschrift:
Journal of Autism and Developmental Disorders > Uitgave 6/2014
Auteurs:
Brittany Peters, Kent C. Williams, Phillip Gorrindo, Daniel Rosenberg, Evon Batey Lee, Pat Levitt, Jeremy Veenstra-VanderWeele
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.​1007/​s10803-013-2009-2) contains supplementary material, which is available to authorized users.

Abstract

Based on clinical experience, we hypothesized that rigid–compulsive behaviors are associated with severe constipation and co-occurring diarrhea or underwear staining in children with autism spectrum disorder. Using data from the Autism Treatment Network, we evaluated the association between these gastrointestinal symptoms and measures of rigid compulsive behavior in children ages 2–17. Following statistical correction, four of five primary measures were significantly associated with constipation and diarrhea or underwear staining, including parental report of repetitive behavior, parental report of compulsive behavior, clinician diagnosis of obsessive–compulsive disorder, and report of rituals observed on the autism diagnostic observation schedule. This association could point to a causal connection between these symptoms or to a common biological pathway that impacts both gut and brain.

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Extra materiaal
Supplementary material 1 (PDF 438 kb)
10803_2013_2009_MOESM1_ESM.pdf
Supplementary material 2 (PDF 836 kb)
10803_2013_2009_MOESM2_ESM.pdf
Supplementary material 3 (PDF 229 kb)
10803_2013_2009_MOESM3_ESM.pdf
Supplementary material 4 (PDF 187 kb)
10803_2013_2009_MOESM4_ESM.pdf
Supplementary material 5 (PDF 216 kb)
10803_2013_2009_MOESM5_ESM.pdf
Supplementary material 6 (PDF 599 kb)
10803_2013_2009_MOESM6_ESM.pdf
Supplementary material 7 (PDF 530 kb)
10803_2013_2009_MOESM7_ESM.pdf
Supplementary material 8 (DOC 61 kb)
10803_2013_2009_MOESM8_ESM.doc
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Journal of Autism and Developmental Disorders 6/2014Naar de uitgave