Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-07-2010 | Original Paper

Right Hemisphere Dysfunction and Metaphor Comprehension in Young Adults with Asperger Syndrome

Auteurs: Rinat Gold, Miriam Faust

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2010

Abstract

This study examined whether the known difficulties in metaphor comprehension exhibited by persons with Asperger syndrome (AS) can be explained by a dysfunctional right hemisphere (RH). Using the divided visual field paradigm, 27 AS participants and 36 matched controls were presented with word pairs of four types (literal, conventional metaphors, novel metaphors, and unrelated word pairs), and were asked to perform a semantic judgment task. The main hypothesis was that whereas the control group participants will show RH superiority for novel metaphor processing, no RH superiority will be found in the AS group. Results indeed indicate much less RH contribution to novel metaphor comprehension in AS, and are discussed in light of linguistic models and the neurobiology of autism.

vorige artikel Using the Childhood Autism Rating Scale to Diagnose Autism Spectrum Disorders

volgende artikel Social Story™ Interventions for Students with Autism Spectrum Disorders: A Meta-Analysis

Alleen toegankelijk voor geautoriseerde gebruikers

American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association.

Anaki, D., Faust, M., & Kravetz, S. (1998). Cerebral hemisphereic asymmetries in processing lexical metaphors. Neuropsychologia, 36, 339–350.

Arzouan, Y., Goldstein, A., & Faust, M. (2007a). Dynamics of hemispheric activity during metaphor comprehension: Electrophysiological measures. NeuroImage, 36, 222–231.CrossRefPubMed

Arzouan, Y., Goldstein, A., & Faust, M. (2007b). Brainwaves are stethoscopes: ERP correlates of novel metaphor comprehension. Brain Research, 1160, 69–81.CrossRefPubMed

Attwood, T. (1998). Asperger`s syndrome: A guide for parents and professionals. London: Jessica Kingsley.

Baltaxe, C. A. M., & Simmons, J. Q. (1992). A comparison of language issues in high functioning autism and related disorders with onset in childhood and adolescence. In E. Schopler & G. B. Mesibov (Eds.), High-functioning individuals with autism (pp. 201–225). New-York: Plenum.

Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient: Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17.CrossRefPubMed

Berthier, M. L., Starkstein, S. E., & Leiguarda, R. (1990). Developmental cortical anomalies in Asperger’s syndrome: Neuroradiological findings in two patients. Journal of Neuropsychiatry and Clinical Neuroscience, 2(2), 197–201.

Beeman, M., Friedman, R. B., Grafman, J., Perez, E., et al. (1994). Summation priming and coarse semantic coding in the right hemisphere. Journal of Cognitive Neuroscience, 6(1), 26–45.CrossRef

Berthier, M. L., Bayes, A., & Tolosa, E. S. (1993). Magnetic resonance imaging in patients with concurrent Tourette`s disorder and Asperger syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 633–639.CrossRefPubMed

Bottini, G., Corcoran, R., Sterzi, R., Paulesu, E., Schenone, P., Scarpa, P., et al. (1994). The role of the right hemisphere in the interpretation of figurative aspects of language. A positron emission tomography activation study. Brain, 117(6), 1241–1253.CrossRefPubMed

Bowdle, B. F., & Gentner, D. (2005). The career of metaphor. Psychological Review, 112, 193–216.CrossRefPubMed

Burgess, C., & Simpson, G. (1988). Cerebral hemispheric mechanisms in the retrieval of ambiguous word meanings. Brain and Language, 3, 86–103.CrossRef

Chiarello, C. (1991). Interpretation of word meanings in the cerebral hemispheres: One is not enough. In P. J. Schwanenflugel (Ed.), The psychology of word meanings (pp. 251–275). Hillsdale, NJ: Erlbaum.

Chiarello, C. (2003). Parallel systems for processing language: Hemispheric complementarity in the normal brain. In M. T. Banich & M. Mack (Eds.), Mind, brain and language (pp. 229–247). Mahwah, NJ: Erlbaum.

Chugani, D. C. (2004). Serotonin in autism and pediatric epilepsies. Mental Retardation and Developmental Disorders Research Reviews, 10, 112–116.CrossRef

Chwilla, D. J. & Kolk, H. H. J. (1999). ERP and RT evidence for inhibition between alternative meanings of ambiguous words, Poster presented at the 40th annual meeting of the Psychnomic Society.

Courchesne, E., Townsend, J., Akahoomoff, N. A., Saitoh, O., Yeung-Courchesne, R., Lincoln, A. J., et al. (1994). Impairment in shifting attention in autistic and cerebellar patients. Behavioral Neuroscience, 108, 848–865.CrossRefPubMed

Dennis, M., Lazenby, A. L., & Lockyer, L. (2001). Inferential language in highfunctioning children with autism. Journal of Autism and Developmental Disorders, 31(1), 47–54.CrossRefPubMed

Ellis, H. D., Ellis, D. M., Fraser, W., & Deb, S. (1994). A preliminary study of right hemisphere cognitive deficit and impaired social judgments among young people with Asperger syndrome. European Child and Adolescent Psychiatry, 3, 255–266.CrossRef

Emerich, D. M., Creaghead, N. A., Grether, S. M., Murray, D., & Grasha, C. (2003). The comprehension of humorous materials by adolescents with high functioning autism and Asperger’s syndrome. Journal of Autism and Developmental Disorders, 33(3), 253–257.CrossRefPubMed

Faust, M., & Lavidor, M. (2003). Semantically convergent and semantically divergent priming in cerebral hemispheres: Lexical decision and semantic judgment. Cognitive and Brain Research, 17, 585–597.CrossRef

Faust, M., & Mashal, N. (2007). The role of the right cerebral hemisphere in processing novel metaphoric expressions taken from poetry: A divided visual field study. Neuropsychologia, 45, 860–870.CrossRefPubMed

Fine, J., Bartolucci, G., Ginsberg, G., & Szatmari, P. (1991). The use of intonation to communicate in pervasive developmental disorders. Journal of Child Psychology and Psychiatry and Allied Disciplines, 32(5), 771–782.CrossRef

Ghaziuddin, M., Thomas, P., Napier, E., Kearny, G., Tsai, L., Welch, K., et al. (2000). Brief report: Brief syntactic analysis in Asperger syndrome: A preliminary study. Journal of Autism and Developmental Disorders, 30(1), 67–70.CrossRefPubMed

Gillberg, C., & Gillberg, I. C. (1989). Asperger syndrome—Some epidemiological considerations: A research note. Journal of Child Psychology and Psychiatry, 30, 631–638.CrossRefPubMed

Giora, R. (1997). Understanding figurative and literal language: The graded salience hypothesis. Cognitive Linguistics, 7, 183–206.CrossRef

Giora, R. (2003). On our mind: Salience, context and figurative language. New York: Oxford University Press.

Giora, R., Zaidel, E., Soroker, N., Batori, G., & Kasher, A. (2000). Differential effects of right- and left- hemisphere damage on understanding sarcasm and metaphor. Metaphor and Symbol, 15, 63–83.CrossRef

Golan, O., Gold, R., & Fridenzon, S. (2009). The Hebrew version of the autism spectrum quotient (AQ-Heb) as a screening instrument for adults with autism spectrum conditions, Poster presented at the 8th annual international meeting for autism research (IMFAR), Chicago.

Gunter, H. L., Ghaziuddin, M., & Ellis, H. D. (2002). Asperger syndrome: Test of right hemisphere and interhemispheric communication. Journal of Autism and Developmental Disorders, 32(4), 263–281.CrossRefPubMed

Herbert, M. R., Ziegler, D. A., Makris, N., Filipek, P. A., Kemper, T. L., Normandin, J. J., et al. (2004). Localization of white matter volume increase in autism and developmental language disorder. Annals of Neurology, 55, 530–540.CrossRefPubMed

Hutsler, J., & Galuske, R. A. W. (2003). Hemispheric asymmetries in cerebral cortical networks. Trends in Neurosciences, 26(8), 429–435.CrossRefPubMed

Inui, N., & Suzuki, K. (1998). Practice and serial reaction time of adolescents with autism. Perception and Motor Skills, 86, 403–410.

Jansson-Verkasalo, E., Ceponiene, R., Kielinen, M., Suominen, K., Jantti, V., Linna, S. L., et al. (2003). Deficient auditory processing in children with Asperger syndrome, as indexed by event-related potentials. Neuroscience Letters, 338(3), 197–200.CrossRefPubMed

Jolliffe, T., & Baron-Cohen, S. (1999a). A test of central coherence theory: Linguistic processing in high-functioning adults with autism or Asperger syndrome: Is local coherence impaired? Cognition, 71(2), 149–185.CrossRefPubMed

Jolliffe, T., & Baron-Cohen, S. (1999b). The strange stories test: A replication with high-functioning adults with autism or Asperger syndrome. Journal of Autism and Developmental Disorders, 29(5), 395–406.CrossRefPubMed

Jolliffe, T., & Baron-Cohen, S. (2000). Linguistic processing in high-functioning adults with autism or Asperger’s syndrome. Is global coherence impaired? Psychological Medicine, 30(5), 1169–1187.CrossRefPubMed

Jung-Beeman, M. (2005). Bilateral brain processes for comprehending natural language. Trends in Cognitive Neuroscience, 9(11), 512–518.CrossRef

Just, M. A., Cherkassky, V. L., Keller, T. A., & Minshew, N. J. (2004). Cortical activation and synchronization during sentence comprehension in high functioning autism: Evidence of underconnectivity. Brain, 127, 1811–1821.CrossRefPubMed

Klin, A., Volkmar, F. R., Sparrow, S. S., Ciccetti, D. V., & Rourke, B. P. (1995). Validity and neuropsychological characterization of Asperger syndrome. Journal Child Psychology and Psychiatry, 36(7), 1127–1140.CrossRef

Kracke, I. (1994). Developmental prosopagnosia in Asperger`s syndrome: Presentation and discussion of an individual case. Developmental and Medical Child Neurology, 36, 873–886.CrossRef

Kujala, T., Lepisto, T., Nieminen-von Wendt, T., Näätänen, P., & Näätänen, R. (2005). Neurophysiological evidence for cortical discrimination impairment of prosody in Asperger syndrome. Neuroscience Letters, 383, 260–265.CrossRefPubMed

Kurita, H., Koyama, T., & Osada, H. (2005). Autism spectrum quotient: Japanese version and its short forms for screening normally intelligent persons with pervasive developmental disorders. Psychiatry and Clinical Neuroscience, 59, 490–496.CrossRef

Lombardo, M. V., Barnes, J. L., Wheelwright, S. J., & Baron-Cohen, S. (2007). Self referential cognition and empathy in autism. PLoS-One, 2(9), e883.CrossRefPubMed

Losh, M., & Capps, L. (2003). Narrative ability in high-functioning children with autism or Asperger`s syndrome. Journal of Autism Developmental Disorders, 33(3), 239–251.CrossRef

MacKay, G., & Shaw, A. (2004). A comparative study of figurative language in children with autistic spectrum disorders. Child Language Teaching and Therapy, 20(1), 13–32.CrossRef

Martin, I., & McDonald, S. (2004). An exploration of non-literal language problems in individuals with Asperger syndrome. Journal of Autism and Developmental Disorders, 34(3), 311–328.CrossRefPubMed

Mashal, N., & Faust, M. (2008). Right hemisphere sensitivity to novel metaphoric relations: Application of the signal detection theory. Brain and Language, 104, 103–112.CrossRefPubMed

Mashal, N., Faust, M., & Hendler, T. (2005). Processing conventional vs. novel metaphors by the two cerebral hemispheres: Application of principle component analysis to fMRI data. Neuropsychologia, 43, 2084–2100.CrossRefPubMed

Mashal, N., Faust, M., Hendler, T., & Jung-Beeman, M. (2007). An fMRI investigation of the neural correlates underlying the processing of novel metaphoric expressions. Brain and Language, 100, 115–126.CrossRefPubMed

McKelvey, J. R., Lambert, R., Mottron, L., & Shevell, M. I. (1995). Right-hemisphere dysfunction in Asperger`s syndrome. Journal of Child Neurology, 10(4), 310–314.CrossRefPubMed

Minshew, N. J., & Williams, D. L. (2007). The new neurobiology of autism—Cortex, connectivity, and neuronal organization. Archives of Neurology, 64(7), 945–950.CrossRefPubMed

Oldfield, D. J. (1971). The assessment of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97–113.CrossRefPubMed

Ovadia, R. (1991). A linguistic characterization of Asperger’s syndrome. Thesis. Department of English, Bar-Ilan University.

Ozonoff, S., Rogers, S., & Pennington, B. F. (2006). Asperger’s syndrome: Evidence of an empirical distinction from high-functioning autism. Journal of Child Psychology and Psychiatry, 32(7), 1107–1122.CrossRef

Pobric, G., Mashal, N., Faust, M., & Lavidor, M. (2008). The role of the right cerebral hemisphere in processing novel metaphoric expressions: A transcranial magnetic stimulation study. Journal of Cognitive Neuroscience, 20(1), 170–181.CrossRefPubMed

Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002). A clinical and neurobehavioral review of high functioning autism and Asperger’s disorder. Australian and New Zealand Journal of Psychiatry, 36(6), 762–770.CrossRefPubMed

Rinehart, N. J., Bradshaw, J. L., Moss, S. A., Ereton, A. V., & Tonge, B. J. (2000). Atypical interference of local detail on global processing in high-functioning autism and Asperger disorder. Journal of Child Psychology and Psychiatry, 41(6), 769–778.CrossRefPubMed

Sabbagh, M. A. (1999). Communicative intentions and language: Evidence from right hemisphere damage and autism. Brain Language, 70, 29–69.CrossRef

Seldon, H. L. (1982). Structure of human auditory cortex. III. Statistical analysis of dendritic trees. Brain Research, 249, 211–221.CrossRefPubMed

Strandburg, R. J., Marsh, J. T., Brown, W. S., Asarnow, R. F., Guthriet, D., & Higa, J. (1993). Event-related potentials in high-functioning adult autistics: Linguistic and nonlinguistic visual information processing tasks. Neuropsychologia, 31(5), 413–434.CrossRefPubMed

Wechsler, D. (1997). WAIS-III administration and scoring manual. San-Antonio: Harcourt Brace and Company.

Weintraub, S., & Mesulam, M. M. (1983). Developmental learning disabilities of the right hemisphere. Archive of Neurology, 40, 463–468.

Whitehouse, D., & Harris, J. C. (1984). Hyperlexia in infantile autism. Journal of Autism and Developmental Disorders, 14(3), 281–289.CrossRefPubMed

Woodbury-Smith, M., Robinson, J., & Baron-Cohen, S. (2005). Screening adults for Asperger syndrome using the AQ: Diagnostic validity in clinical practice. Journal of Autism and Developmental Disorders, 35, 331–335.CrossRefPubMed

Titel: Right Hemisphere Dysfunction and Metaphor Comprehension in Young Adults with Asperger Syndrome
Auteurs: Rinat Gold
Miriam Faust
Publicatiedatum: 01-07-2010
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2010
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-009-0930-1

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 7/2010

Erratum to: Deborah Lipsky, Will Richards: Managing Meltdowns: Using the S.C.A.R.E.D Calming Technique with Children and Adults with Autism

Using the Childhood Autism Rating Scale to Diagnose Autism Spectrum Disorders

Brief Report: Repetitive Behaviours in Greek Individuals with Autism Spectrum Disorder

Brief Report: Predicting Inner Speech Use Amongst Children with Autism Spectrum Disorder (ASD): The Roles of Verbal Ability and Cognitive Profile

Free Classification as a Window on Executive Functioning in Autism Spectrum Disorders

M. Calinescu: Matthew’s Enigma