Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-02-2012 | Original Paper

Reward Circuitry Function in Autism During Face Anticipation and Outcomes

Auteurs: Gabriel S. Dichter, J. Anthony Richey, Alison M. Rittenberg, Antoinette Sabatino, James W. Bodfish

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2012

Abstract

The aim of this study was to investigate reward circuitry responses in autism during reward anticipation and outcomes for monetary and social rewards. During monetary anticipation, participants with autism spectrum disorders (ASDs) showed hypoactivation in right nucleus accumbens and hyperactivation in right hippocampus, whereas during monetary outcomes, participants with ASDs showed hyperactivation in left midfrontal and anterior cingulate gyrus. Groups did not differ in nucleus accumbens responses to faces. The ASD group demonstrated hyperactivation in bilateral amygdala during face anticipation that predicted social symptom severity and in bilateral insular cortex during face outcomes. These results add to the growing body of evidence that autism is characterized by altered functioning of reward circuitry. Additionally, atypical amygdala activation during the processing of social rewards may contribute to the development or expression of autistic features.

volgende artikel Early Childhood Predictors of the Social Competence of Adults with Autism

Alleen toegankelijk voor geautoriseerde gebruikers

Aberman, J. E., Ward, S. J., & Salamone, J. D. (1998). Effects of dopamine antagonists and accumbens dopamine depletions on time-constrained progressive-ratio performance. Pharmacology, Biochemistry and Behavior, 61(4), 341–348.

Abler, B., Greenhouse, I., Ongur, D., Walter, H., & Heckers, S. (2007). Abnormal reward system activation in Mania. Neuropsychopharmacology.

Adcock, R. A., Thangavel, A., Whitfield-Gabrieli, S., Knutson, B., & Gabrieli, J. D. (2006). Reward-motivated learning: Mesolimbic activation precedes memory formation. Neuron, 50(3), 507–517.PubMed

Adolphs, R. (2010). What does the amygdala contribute to social cognition? Annals of the New York Academy of Sciences, 1191(1), 42–61.PubMed

Aharon, I., Etcoff, N., Ariely, D., Chabris, C. F., O’Connor, E., & Breiter, H. C. (2001). Beautiful faces have variable reward value: fMRI and behavioral evidence. Neuron, 32(3), 537–551.PubMed

Ashwin, C., Baron-Cohen, S., Wheelwright, S., O’Riordan, M., & Bullmore, E. T. (2007). Differential activation of the amygdala and the ‘social brain’ during fearful face-processing in Asperger Syndrome. Neuropsychologia, 45(1), 2–14.PubMed

Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17.PubMed

Bechara, A., Damasio, H., & Damasio, A. R. (2000). Emotion, decision making and the orbitofrontal cortex. Cerebral Cortex, 10(3), 295–307.PubMed

Beckmann, C. F., Jenkinson, M., & Smith, S. M. (2003). General multilevel linear modeling for group analysis in FMRI. Neuroimage, 20(2), 1052–1063.PubMed

Berridge, K. C. (1996). Food reward: brain substrates of wanting and liking. Neuroscience and Biobehavioral Reviews, 20(1), 1–25.PubMed

Berridge, K. C., & Robinson, T. E. (1998). What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience? Brain Research Reviews, 28(3), 309–369.PubMed

Bjork, J. M., & Hommer, D. W. (2007). Anticipating instrumentally obtained and passively-received rewards: a factorial fMRI investigation. Behavioural Brain Research, 177(1), 165–170.PubMed

Bodfish, J. W., Symons, F. W., & Lewis, M. H. (1999). The repetitive behavior scale-revised, Western Carolina Center Research Reports.

Bookheimer, S. Y., Wang, A. T., Scott, A., Sigman, M., & Dapretto, M. (2008). Frontal contributions to face processing differences in autism: Evidence from fMRI of inverted face processing. Journal of the International Neuropsychological Society, 14(6), 922–932.PubMed

Boyd, B. A., Conroy, M. A., Mancil, G. R., Nakao, T., & Alter, P. J. (2007). Effects of circumscribed interests on the social behaviors of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(8), 1550–1561.PubMed

Brooks, R., & Meltzoff, A. N. (2002). The importance of eyes: how infants interpret adult looking behavior. Developmental Psychology, 38(6), 958–966.PubMed

Brown, J. W., & Braver, T. S. (2005). Learned predictions of error likelihood in the anterior cingulate cortex. Science, 307(5712), 1118–1121.PubMed

Canli, T., Zhao, Z., Desmond, J. E., Kang, E., Gross, J., & Gabrieli, J. D. (2001). An fMRI study of personality influences on brain reactivity to emotional stimuli. Behavioral Neuroscience, 115(1), 33–42.PubMed

Carr, L., Iacoboni, M., Dubeau, M. C., Mazziotta, J. C., & Lenzi, G. L. (2003). Neural mechanisms of empathy in humans: A relay from neural systems for imitation to limbic areas. Proceedings of the National Academy of Sciences USA, 100(9), 5497–5502.

Chakrabarti, B., Kent, L., Suckling, J., Bullmore, E., & Baron-Cohen, S. (2006). Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces. European Journal of Neuroscience, 23(7), 1944–1948.PubMed

Cloutier, J., Heatherton, T. F., Whalen, P. J., & Kelley, W. M. (2008). Are attractive people rewarding? Sex differences in the neural substrates of facial attractiveness. Journal of Cognitive Neuroscience, 20(6), 941–951.PubMed

Constantino, J. N., Davis, S. A., Todd, R. D., Schindler, M. K., Gross, M. M., Brophy, S. L., et al. (2003). Validation of a brief quantitative measure of autistic traits: Comparison of the social responsiveness scale with the autism diagnostic interview-revised. Journal of Autism and Developmental Disorders, 33(4), 427–433.PubMed

Critchley, H. D., Daly, E. M., Bullmore, E. T., Williams, S. C., Van Amelsvoort, T., Robertson, D. M., et al. (2000). The functional neuroanatomy of social behaviour: Changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain, 123(Pt 11), 2203–2212.PubMed

Dalton, K. M., Kalin, N. H., Grist, T. M., & Davidson, R. J. (2005a). Neural-cardiac coupling in threat-evoked anxiety. Journal of Cognitive Neuroscience, 17(6), 969–980.PubMed

Dalton, K. M., Nacewicz, B. M., Johnstone, T., Schaefer, H. S., Gernsbacher, M. A., Goldsmith, H. H., et al. (2005b). Gaze fixation and the neural circuitry of face processing in autism. Nature Neuroscience, 8(4), 519–526.PubMed

Dapretto, M., Davies, M. S., Pfeifer, J. H., Scott, A. A., Sigman, M., Bookheimer, S. Y., et al. (2006). Understanding emotions in others: Mirror neuron dysfunction in children with autism spectrum disorders. Nature Neuroscience, 9(1), 28–30.PubMed

Dawson, G., Meltzoff, A. N., Osterling, J., Rinaldi, J., & Brown, E. (1998). Children with autism fail to orient to naturally occurring social stimuli. Journal of Autism and Developmental Disorders, 28(6), 479–485.PubMed

Dawson, G., Toth, K., Abbott, R., Osterling, J., Munson, J., & Estes, A. (2004). Defining the early social attention impairments in autism: Social orienting, joint attention, and responses to emotions. Developmental Psychology, 40, 271–283.PubMed

Dawson, G., Webb, S. J., & McPartland, J. (2005). Understanding the nature of face processing impairment in autism: Insights from behavioral and electrophysiological studies. Developmental Neuropsychology, 27(3), 403–424.PubMed

de Lafuente, V., & Romo, R. (2006). Neural correlate of subjective sensory experience gradually builds up across cortical areas. Proceedings of the National Academy of Sciences USA, 103(39), 14266–14271.

de Vignemont, F., & Singer, T. (2006). The empathic brain: How, when and why? Trends Cognitive Science, 10(10), 435–441.

Deco, G., & Rolls, E. T. (2006). Decision-making and Weber’s law: A neurophysiological model. European Journal of Neuroscience, 24(3), 901–916.PubMed

Dichter, G. S., Felder, J., Green, S. R., Rittenberg, A. M., Sasson, N., & Bodfish, J. (2011). Reward circuitry function in autism spectrum disorders. Social Cognitive and Affective Neuroscience (in press).

Dichter, G. S., & Tomarken, A. J. (2008). The chronometry of affective startle modulation in unipolar depression. Journal of Abnormal Psychology, 117(1), 1–15.PubMed

Dillon, D. G., Holmes, A. J., Jahn, A. L., Bogdan, R., Wald, L. L., & Pizzagalli, D. A. (2008). Dissociation of neural regions associated with anticipatory versus consummatory phases of incentive processing. Psychophysiology, 45(1), 36–49.PubMed

Eichenbaum, H. (2000). A cortical-hippocampal system for declarative memory. Nature Reviews of Neuroscience, 1(1), 41–50.

Emery, N. J. (2000). The eyes have it: The neuroethology, function and evolution of social gaze. Neuroscience and Biobehavioral Reviews, 24(6), 581–604.PubMed

Farroni, T., Csibra, G., Simion, F., & Johnson, M. H. (2002). Eye contact detection in humans from birth. Proceedings of the National Academy of Sciences USA, 99(14), 9602–9605.

Fischl, B., Sereno, M. I., & Dale, A. M. (1999a). Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. Neuroimage, 9(2), 195–207.PubMed

Fischl, B., Sereno, M. I., Tootell, R. B., & Dale, A. M. (1999b). High-resolution intersubject averaging and a coordinate system for the cortical surface. Human Brain Mapping, 8(4), 272–284.PubMed

Fletcher, P. C., & Henson, R. N. (2001). Frontal lobes and human memory: Insights from functional neuroimaging. Brain, 124(Pt 5), 849–881.PubMed

Forbes, E. E., Hariri, A. R., Martin, S. L., Silk, J. S., Moyles, D. L., Fisher, P. M., et al. (2009). Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder. American Journal of Psychiatry, 166(1), 64–73.PubMed

Friedman, D. P., Aggleton, J. P., & Saunders, R. C. (2002). Comparison of hippocampal, amygdala, and perirhinal projections to the nucleus accumbens: Combined anterograde and retrograde tracing study in the Macaque brain. Journal of Comparative Neurology, 450(4), 345–365.PubMed

Gallese, V., Fadiga, L., Fogassi, L., & Rizzolatti, G. (1996). Action recognition in the premotor cortex. Brain, 119(Pt 2), 593–609.PubMed

Gottfried, J. A., O’Doherty, J., & Dolan, R. J. (2003). Encoding predictive reward value in human amygdala and orbitofrontal cortex. Science, 301(5636), 1104–1107.PubMed

Grelotti, D. J., Klin, A. J., Gauthier, I., Skudlarski, P., Cohen, D. J., Gore, J. C., et al. (2005). fMRI activation of the fusiform gyrus and amygdala to cartoon characters but not to faces in a boy with autism. Neuropsychologia, 43(3), 373–385.PubMed

Haber, S. N., & Knutson, B. (2010). The reward circuit: Linking primate anatomy and human imaging. Neuropsychopharmacology, 35(1), 4–26.PubMed

Hadjikhani, N., Joseph, R. M., Snyder, J., & Tager-Flusberg, H. (2007). Abnormal activation of the social brain during face perception in autism. Human Brain Mapping, 28(5), 441–449.PubMed

Hayden, B. Y., Parikh, P. C., Deaner, R. O., & Platt, M. L. (2007). Economic principles motivating social attention in humans. Proceedings Biological Sciences, 274(1619), 1751–1756.

Hempel, R. J., Tulen, J. H., van Beveren, N. J., van Steenis, H. G., Mulder, P. G., & Hengeveld, M. W. (2005). Physiological responsivity to emotional pictures in schizophrenia. Journal of Psychiatric Research, 39(5), 509–518.PubMed

Howes, O. D., & Kapur, S. (2009). The dopamine hypothesis of schizophrenia: Version III-the final common pathway. Schizophrenia Bulletin, 35(3), 549–562.PubMed

Hsu, M., Bhatt, M., Adolphs, R., Tranel, D., & Camerer, C. F. (2005). Neural systems responding to degrees of uncertainty in human decision-making. Science, 310(5754), 1680–1683.PubMed

Ikemoto, S., & Panksepp, J. (1999). The role of nucleus accumbens dopamine in motivated behavior: A unifying interpretation with special reference to reward-seeking. Brain Research. Brain Research Reviews, 31(1), 6–41.PubMed

Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002). Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage, 17(2), 825–841.PubMed

Jenkinson, M., & Smith, S. (2001). A global optimisation method for robust affine registration of brain images. Medical Image Analysis, 5(2), 143–156.PubMed

Johnson, S. A., Filliter, J. H., & Murphy, R. R. (2009). Discrepancies between self- and parent-perceptions of autistic traits and empathy in high functioning children and adolescents on the autism spectrum. J Autism Dev Disord.

Juckel, G., Schlagenhauf, F., Koslowski, M., Filonov, D., Wustenberg, T., Villringer, A., et al. (2006a). Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics. Psychopharmacology (Berlin), 187(2), 222–228.

Juckel, G., Schlagenhauf, F., Koslowski, M., Wustenberg, T., Villringer, A., Knutson, B., et al. (2006b). Dysfunction of ventral striatal reward prediction in schizophrenia. Neuroimage, 29(2), 409–416.PubMed

Juranek, J., Filipek, P. A., Berenji, G. R., Modahl, C., Osann, K., & Spence, M. A. (2006). Association between amygdala volume and anxiety level: Magnetic resonance imaging (MRI) study in autistic children. Journal of Child Neurology, 21(12), 1051–1058.PubMed

Kable, J. W., & Glimcher, P. W. (2007). The neural correlates of subjective value during intertemporal choice. Nature Neuroscience, 10(12), 1625–1633.PubMed

Kim, H., Shimojo, S., & O’Doherty, J. P. (2006). Is avoiding an aversive outcome rewarding? Neural substrates of avoidance learning in the human brain. PLoS Biology, 4(8), e233.

Kleinhans, N. M., Johnson, L. C., Richards, T., Mahurin, R., Greenson, J., Dawson, G., et al. (2009). Reduced neural habituation in the amygdala and social impairments in autism spectrum disorders. American Journal of Psychiatry, 166(4), 467–475.PubMed

Klin, A., Jones, W., Schultz, R., Volkmar, F., & Cohen, D. (2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry, 59(9), 809–816.PubMed

Klin, A., Lin, D. J., Gorrindo, P., Ramsay, G., & Jones, W. (2009). Two-year-olds with autism orient to non-social contingencies rather than biological motion. Nature, 459(7244), 257–261.PubMed

Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001). Anticipation of increasing monetary reward selectively recruits nucleus accumbens. Journal of Neuroscience, 21(16), RC159.

Knutson, B., & Cooper, J. C. (2005). Functional magnetic resonance imaging of reward prediction. Current Opinion in Neurology, 18(4), 411–417.PubMed

Knutson, B., Fong, G. W., Adams, C. M., Varner, J. L., & Hommer, D. (2001b). Dissociation of reward anticipation and outcome with event-related fMRI. Neuroreport, 12(17), 3683–3687.PubMed

Knutson, B., & Greer, S. M. (2008). Review. Anticipatory affect: neural correlates and consequences for choice. Philosophical Transactions of the Royal Society of London Series B: Biological Sciences.

Knutson, B., Rick, S., Wimmer, G. E., Prelec, D., & Loewenstein, G. (2007). Neural predictors of purchases. Neuron, 53(1), 147–156.PubMed

Knutson, B., Westdorp, A., Kaiser, E., & Hommer, D. (2000). FMRI visualization of brain activity during a monetary incentive delay task. Neuroimage, 12(1), 20–27.PubMed

Kuhl, P. K., Coffey-Corina, S., Padden, D., & Dawson, G. (2005). Links between social and linguistic processing of speech in preschool children with autism: behavioral and electrophysiological measures. Developmental Science, 8, F1–F12.PubMed

Labar, K. S. (2007). Beyond fear emotional memory mechanisms in the human brain. Current Directions in Psychological Science, 16(4), 173–177.PubMed

Lam, K. S., & Aman, M. G. (2007). The repetitive behavior scale-revised: Independent validation in individuals with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(5), 855–866.PubMed

Le Van Quyen, M., Bragin, A., Staba, R., Crepon, B., Wilson, C. L., & Engel, J., Jr. (2008). Cell type-specific firing during ripple oscillations in the hippocampal formation of humans. Journal of Neuroscience, 28(24), 6104–6110.PubMed

Liang, X., Zebrowitz, L. A., & Zhang, Y. (2010). Neural activation in the “reward circuit” shows a nonlinear response to facial attractiveness. Social Neuroscience, 5(3), 320–334.PubMed

Lombardo, M. V., Chakrabarti, B., & Baron-Cohen, S. (2009). The amygdala in autism: Not adapting to faces? American Journal of Psychiatry, 166(4), 395–397.PubMed

Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMed

MacDonald, A. W., 3rd, Cohen, J. D., Stenger, V. A., & Carter, C. S. (2000). Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science, 288(5472), 1835–1838.PubMed

Magno, E., Foxe, J. J., Molholm, S., Robertson, I. H., & Garavan, H. (2006). The anterior cingulate and error avoidance. Journal of Neuroscience, 26(18), 4769–4773.PubMed

McCabe, C., Mishor, Z., Cowen, P. J., & Harmer, C. J. (2010). Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. Biological Psychiatry, 67(5), 439–445.PubMed

Monk, C. S., Weng, S. J., Wiggins, J. L., Kurapati, N., Louro, H. M., Carrasco, M., et al. (2010). Neural circuitry of emotional face processing in autism spectrum disorders. Journal of Psychiatry Neuroscience, 35(2), 105–114.PubMed

Munson, J., Dawson, G., Abbott, R., Faja, S., Webb, S. J., Friedman, S. D., et al. (2006). Amygdalar volume and behavioral development in autism. Archives of General Psychiatry, 63(6), 686–693.PubMed

Nishitani, N., Avikainen, S., & Hari, R. (2004). Abnormal imitation-related cortical activation sequences in Asperger’s syndrome. Annals of Neurology, 55(4), 558–562.PubMed

O’Doherty, J., Winston, J., Critchley, H., Perrett, D., Burt, D. M., & Dolan, R. J. (2003). Beauty in a smile: The role of medial orbitofrontal cortex in facial attractiveness. Neuropsychologia, 41(2), 147–155.PubMed

Oberman, L. M., Hubbard, E. M., McCleery, J. P., Altschuler, E. L., Ramachandran, V. S., & Pineda, J. A. (2005). EEG evidence for mirror neuron dysfunction in autism spectrum disorders. Brain Research. Cognitive Brain Research, 24(2), 190–198.PubMed

Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003). Neurobiology of emotion perception I: The neural basis of normal emotion perception. Biological Psychiatry, 54(5), 504–514.PubMed

Pierce, K., Muller, R. A., Ambrose, J., Allen, G., & Courchesne, E. (2001). Face processing occurs outside the fusiform ‘face area’ in autism: Evidence from functional MRI. Brain, 124(Pt 10), 2059–2073.PubMed

Pinkham, A. E., Hopfinger, J. B., Pelphrey, K. A., Piven, J., & Penn, D. L. (2008). Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders. Schizophrenia Research, 99(1–3), 164–175.PubMed

Rademacher, L., Krach, S., Kohls, G., Irmak, A., Grunder, G., & Spreckelmeyer, K. N. (2010). Dissociation of neural networks for anticipation and consumption of monetary and social rewards. Neuroimage, 49(4), 3276–3285.PubMed

Rehme, A. K., Frommann, I., Peters, S., Block, V., Bludau, J., Quednow, B. B., Maier, W., Schutz, C., & Wagner, M. (2009). Startle cue-reactivity differentiates between light and heavy smokers. Addiction.

Ridderinkhof, K. R., Ullsperger, M., Crone, E. A., & Nieuwenhuis, S. (2004). The role of the medial frontal cortex in cognitive control. Science, 306(5695), 443–447.PubMed

Roid, G. H., & Miller, L. J. (1997). Leiter international performance scale-revised. Woodale, IL: Stoelting Co.

Rolls, E. T. (1996). The orbitofrontal cortex. In Philosophical Transactions of the royal society of London—series B: Biological sciences (Vol. 351, pp. 1433-1443).

Rolls, E. T., & Grabenhorst, F. (2008). The orbitofrontal cortex and beyond: From affect to decision-making. Progress in Neurobiology, 86(3), 216–244.PubMed

Sasson, N., Tsuchiya, N., Hurley, R., Couture, S. M., Penn, D. L., Adolphs, R., et al. (2007). Orienting to social stimuli differentiates social cognitive impairment in autism and schizophrenia. Neuropsychologia, 45(11), 2580–2588.PubMed

Sasson, N., Turner-Brown, L., Holtzclaw, T., Lam, K. S., & Bodfish, J. (2008). Children with autism demonstrate circumscribed attention during passive viewing of complex social and nonsocial picture arrays. Autism Research, 1, 31–42.PubMed

Schmitz, N., Rubia, K., van Amelsvoort, T., Daly, E., Smith, A., & Murphy, D. G. (2008). Neural correlates of reward in autism. British Journal of Psychiatry, 192, 19–24.PubMed

Schultz, W. (1998). Predictive reward signal of dopamine neurons. Journal of Neurophysiology, 80(1), 1–27.PubMed

Schultz, W. (2000). Multiple reward signals in the brain. Nature Reviews of Neuroscience, 1(3), 199–207.

Schultz, R. T. (2005). Developmental deficits in social perception in autism: The role of the amygdala and fusiform face area. International Journal of Developmental Neuroscience, 23(2–3), 125–141.PubMed

Schultz, R. T., Gauthier, I., Klin, A., Fulbright, R. K., Anderson, A. W., Volkmar, F., et al. (2000). Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome. Archives of General Psychiatry, 57(4), 331–340.PubMed

Scott-Van Zeeland, A. A., Dapretto, M., Ghahremani, D. G., Poldrack, R. A., & Bookheimer, S. Y. (2010). Reward processing in autism. Autism Research, 3(2), 53–67.PubMed

Shabel, S. J., & Janak, P. H. (2009). Substantial similarity in amygdala neuronal activity during conditioned appetitive and aversive emotional arousal. Proceedings of the National Academy of Sciences USA, 106(35), 15031–15036.

Singer, T., Seymour, B., O’Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004). Empathy for pain involves the affective but not sensory components of pain. Science, 303(5661), 1157–1162.PubMed

Smith, S. M. (2002). Fast robust automated brain extraction. Human Brain Mapping, 17(3), 143–155.PubMed

Smith, S. M., Jenkinson, M., Woolrich, M. W., Beckmann, C. F., Behrens, T. E. J., Johansen-Berg, H., et al. (2004). Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage, 23(Suppl 1), S208–S219.PubMed

Smoski, M. J., Felder, J., Bizzell, J., Green, S. R., Ernst, M., Lynch, T. R., et al. (2009). fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorder. Journal of Affective Disorders, 118(1–3), 69–78.PubMed

Stice, E., Yokum, S., Bohon, C., Marti, N., & Smolen, A. (2010). Reward circuitry responsivity to food predicts future increases in body mass: moderating effects of DRD2 and DRD4. Neuroimage, 50(4), 1618–1625.PubMed

Tottenham, N., Tanaka, J. W., Leon, A. C., McCarry, T., Nurse, M., Hare, T. A., et al. (2009). The NimStim set of facial expressions: judgments from untrained research participants. Psychiatry Research, 168(3), 242–249.PubMed

Walton, M. E., Bannerman, D. M., Alterescu, K., & Rushworth, M. F. (2003). Functional specialization within medial frontal cortex of the anterior cingulate for evaluating effort-related decisions. Journal of Neuroscience, 23(16), 6475–6479.PubMed

Walton, M. E., Bannerman, D. M., & Rushworth, M. F. (2002). The role of rat medial frontal cortex in effort-based decision making. Journal of Neuroscience, 22(24), 10996–11003.PubMed

Weng, S. J., Carrasco, M., Swartz, J. R., Wiggins, J. L., Kurapati, N., Liberzon, I., Risi, S., Lord, C., & Monk, C. S. (2010). Neural activation to emotional faces in adolescents with autism spectrum disorders. J Child Psychol Psychiatry.

Weschler, D. (1999). Weschler abbreviated scale of intelligence (WASI). San Antonio, TX: Harcourt Assessment.

Wicker, B., Keysers, C., Plailly, J., Royet, J. P., Gallese, V., & Rizzolatti, G. (2003). Both of us disgusted in My insula: the common neural basis of seeing and feeling disgust. Neuron, 40(3), 655–664.PubMed

Williams, J. H. G. (2008). Self-other relations in social development and for mirror neurons and other brain bases. Autism Research, 1, 73–90.PubMed

Willner, P. (1983). Dopamine and depression: a review of recent evidence. III. The effects of antidepressant treatments. Brain Research, 287(3), 237–246.PubMed

Winston, J. S., O’Doherty, J., Kilner, J. M., Perrett, D. I., & Dolan, R. J. (2007). Brain systems for assessing facial attractiveness. Neuropsychologia, 45(1), 195–206.PubMed

Wise, R. A. (2008). Dopamine and reward: The anhedonia hypothesis 30 years on. Neurotoxicity Research, 14(2–3), 169–183.PubMed

Woolrich, M. W., Ripley, B. D., Brady, M., & Smith, S. M. (2001). Temporal autocorrelation in univariate linear modeling of FMRI data. Neuroimage, 14(6), 1370–1386.PubMed

Xi, Z. X., & Gardner, E. L. (2008). Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. Current Drug Abuse Reviews, 1(3), 303–327.PubMed

Titel: Reward Circuitry Function in Autism During Face Anticipation and Outcomes
Auteurs: Gabriel S. Dichter
J. Anthony Richey
Alison M. Rittenberg
Antoinette Sabatino
James W. Bodfish
Publicatiedatum: 01-02-2012
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 2/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-011-1221-1

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 2/2012

Bullying Experiences Among Children and Youth with Autism Spectrum Disorders

Outcomes of Behavioral Intervention for Children with Autism in Mainstream Pre-School Settings

The Effect of an Autism-Associated Polymorphism in the STK39 Gene on the Autism Symptom Domains

The Effects of Face Expertise Training on the Behavioral Performance and Brain Activity of Adults with High Functioning Autism Spectrum Disorders

M. Augustyn, B. Zuckerman and E.B. Caronna (eds.): The Zuckerman Parker Handbook of Developmental and Behavioral Pediatrics for Primary Care

Evidence for a Cultural Influence on Field-Independence in Autism Spectrum Disorder