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05-10-2015 | Review Article | Uitgave 11/2015 Open Access

Netherlands Heart Journal 11/2015

Revealing the impact of local access-site complications and upper extremity dysfunction post transradial percutaneous coronary procedures

Netherlands Heart Journal > Uitgave 11/2015
E.M. Zwaan, A.G.M.M. Koopman, C.A.J. Holtzer, F. Zijlstra, M.J.P.F. Ritt, G. Amoroso, E. Moerman, M.J.M. Kofflard, A.A.J. IJsselmuiden
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Electronic supplementary material

The online version of this article (doi: 10.​1007/​s12471-015-0747-9) contains supplementary material, which is available to authorized users. This supplementary file contains References 51–202.



Little is known about local access-site complications and upper extremity dysfunction after transradial percutaneous coronary procedures (TR-PCP). This systematic review study aimed to summarise the current knowledge on the incidences of access-site complications and upper extremity dysfunction after TR-PCP.


Two independent, trained investigators searched MEDLINE, EMBASE and CENTRAL for eligible studies published before 1 January 2015. Also, they hand-searched the conference proceedings of the annual scientific sessions of the American College of Cardiology, the American Heart Association, European Society of Cardiology, and the Trans-catheter Cardiovascular Therapeutics. Inclusion criteria were cohort studies and clinical trials discussing the incidence of access-site complications and upper extremity function after transradial percutaneous coronary intervention (TR-PCI) and/or transradial coronary angiography (TR-CAG) as endpoints.


176 articles described access-site complications. The incidence is up to 9.6 %. Fourteen articles described upper extremity dysfunction, with an incidence of up to 1.7 %. Upper extremity dysfunction was rarely investigated, hardly ever as primary endpoint, and if investigated not thoroughly enough.


Upper extremity dysfunction in TR-PCP has never been properly investigated and is therefore underestimated. Further studies are needed to investigate the magnitude, prevention and best treatment of upper extremity dysfunction. Optimising TR-PCP might be achieved by using slender techniques, detection of upper extremity dysfunction and early referral to a hand rehabilitation centre.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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