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Gepubliceerd in: Tijdschrift voor Urologie 5/2015

01-09-2015

Resultaten van semencryopreservatie en gebruik voor kunstmatige voortplantingstechnieken bij 898 mannen met kanker

Semencryopreservatie bij mannen met kanker

Auteurs: drs. I. Muller, dr. ir. R.J.A. Oude Ophuis, prof. dr. F.J.M. Broekmans, drs. M.T.W.T. Lock

Gepubliceerd in: Tijdschrift voor Urologie | Uitgave 5/2015

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Samenvatting

Doelstelling:

Bepalen hoe vaak ingevroren semen van kankerpatiënten wordt gebruikt en het slagingspercentage van kunstmatige voortplantingstechnieken (ART) in deze groep.

Studieopzet:

Retrospectieve data-analyse.

Setting:

Tertiair academische fertiliteitscentrum voortplantingsgeneeskunde.

Patiënten:

898 mannelijke kankerpatiënten die tussen 1983 en 2013 semen lieten invriezen.

Interventie:

Follow-up van alle ART-behandelingen.

Belangrijkste uitkomstmaten:

Gebruik van het ingevroren semen en het slagingspercentage van kunstmatige voortplantingstechnieken (ART) met het ingevroren semen voor het bereiken van het ouderschap.

Resultaten:

898 patiënten vroren hun semen in. 96 patiënten gebruikten hun ingevroren semen voor ART (10,7%). Het percentage klinische zwangerschap voor intra-uteriene inseminatie (IUI), in-vitrofertilisatie (IVF), intracytoplasmatische sperma-injectie (ICSI) en cryo-embryotransfer (ET) waren respectievelijk 14%, 37%, 38% en 18%. In totaal bereikte 77% van de paren ouderschap van ten miste één levendgeborene.

Conclusie:

Hoewel de slagingspercentages van ART met ingevroren semen indrukwekkend zijn, wordt het ingevroren semen van kankerpatiënten (te) weinig gebruikt.

Trefwoorden:

cryopreservatie, semen, kanker, kunstmatige voortplantingstechnieken
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Metagegevens
Titel
Resultaten van semencryopreservatie en gebruik voor kunstmatige voortplantingstechnieken bij 898 mannen met kanker
Semencryopreservatie bij mannen met kanker
Auteurs
drs. I. Muller
dr. ir. R.J.A. Oude Ophuis
prof. dr. F.J.M. Broekmans
drs. M.T.W.T. Lock
Publicatiedatum
01-09-2015
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Tijdschrift voor Urologie / Uitgave 5/2015
Print ISSN: 2211-3037
Elektronisch ISSN: 2211-4718
DOI
https://doi.org/10.1007/s13629-015-0026-y

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