Skip to main content
Top
Gepubliceerd in:

23-07-2024 | ORIGINAL PAPER

Resting-State Functional Connectivity Associated with Non-Judgmental Awareness Predicted Multiple Measures of Negative Affect

Auteurs: Yi-Sheng Wong, Savannah Siew, Junhong Yu

Gepubliceerd in: Mindfulness | Uitgave 8/2024

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Objectives

In recent years, an increasing number of studies have highlighted the usefulness of the Five Facet Mindfulness Questionnaire (FFMQ) in identifying varying levels of trait mindfulness. As higher trait mindfulness (as reflected by higher FFMQ scores) has been associated with fewer negative affective symptoms, a thorough understanding of the neural correlates associated with FFMQ scores would inform the development of more individualized mindfulness interventions. The current study investigated how individual differences in trait mindfulness are related to different resting-state functional connectivity patterns, and whether these patterns could predict negative affective symptoms.

Methods

We analyzed data from 71 adults (age range: 20–45 years) from the Max Planck Institute-Leipzig Mind-Brain-Body dataset. Participants completed the FFMQ, the Beck Depression Inventory-II, and the Hospital Anxiety and Depression Scale, underwent resting-state functional magnetic resonance imaging scans and reported the content of thought emerged during the scanning session. Network-based statistics were used to identify resting-state networks that were significantly associated with the FFMQ facets. The strengths of these networks were then used to predict negative affective symptoms.

Results

Results indicated that higher scores on the facets of act with awareness and nonjudge were associated with fewer negative affective symptoms. The network-based statistics revealed networks of edges that were significantly associated with the facet of nonjudge. Moreover, this network significantly predicted multiple measures of negative affect. There were no networks that were significantly associated with other facets.

Conclusions

These findings provide evidence at the neural level to suggest that the facet of nonjudge is inversely linked to negative affective symptoms.

Preregistration

This study was not preregistered.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
go back to reference Baldwin, J. M. (1901). Dictionary of Philosophy and Psychology. New York Macmillan. Baldwin, J. M. (1901). Dictionary of Philosophy and Psychology. New York Macmillan.
go back to reference Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the Beck Depression Inventory-II. Psychological Corporation. Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the Beck Depression Inventory-II. Psychological Corporation.
go back to reference Brewer, J. A., Worhunsky, P. D., Gray, J. R., Tang, Y.-Y., Weber, J., & Kober, H. (2011). Meditation experience is associated with differences in default mode network activity and connectivity. Proceedings of the National Academy of Sciences, 108(50), 20254–20259. https://doi.org/10.1073/pnas.1112029108CrossRef Brewer, J. A., Worhunsky, P. D., Gray, J. R., Tang, Y.-Y., Weber, J., & Kober, H. (2011). Meditation experience is associated with differences in default mode network activity and connectivity. Proceedings of the National Academy of Sciences, 108(50), 20254–20259. https://​doi.​org/​10.​1073/​pnas.​1112029108CrossRef
go back to reference Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Routledge Academic. Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Routledge Academic.
go back to reference Dixon, M. L., De La Vega, A., Mills, C., Andrews-Hanna, J., Spreng, R. N., Cole, M. W., & Christoff, K. (2018). Heterogeneity within the frontoparietal control network and its relationship to the default and dorsal attention networks. Proceedings of the National Academy of Sciences, 115(7), E1598–E1607. https://doi.org/10.1073/pnas.1715766115CrossRef Dixon, M. L., De La Vega, A., Mills, C., Andrews-Hanna, J., Spreng, R. N., Cole, M. W., & Christoff, K. (2018). Heterogeneity within the frontoparietal control network and its relationship to the default and dorsal attention networks. Proceedings of the National Academy of Sciences, 115(7), E1598–E1607. https://​doi.​org/​10.​1073/​pnas.​1715766115CrossRef
go back to reference Esteban, O., Markiewicz, C. J., Blair, R. W., Moodie, C. A., Isik, A. I., Erramuzpe, A., Kent, J. D., Goncalves, M., DuPre, E., Snyder, M., Oya, H., Ghosh, S. S., Wright, J., Durnez, J., Poldrack, R. A., & Gorgolewski, K. J. (2019). fMRIPrep: A robust preprocessing pipeline for functional MRI. Nature Methods, 16(1), 111–116. https://doi.org/10.1038/s41592-018-0235-4CrossRefPubMed Esteban, O., Markiewicz, C. J., Blair, R. W., Moodie, C. A., Isik, A. I., Erramuzpe, A., Kent, J. D., Goncalves, M., DuPre, E., Snyder, M., Oya, H., Ghosh, S. S., Wright, J., Durnez, J., Poldrack, R. A., & Gorgolewski, K. J. (2019). fMRIPrep: A robust preprocessing pipeline for functional MRI. Nature Methods, 16(1), 111–116. https://​doi.​org/​10.​1038/​s41592-018-0235-4CrossRefPubMed
go back to reference Hautzinger, M., Bailer, M., Worall, H., & Keller, F. (1995). BDI: Beck-Depressions-Inventar Testhandbuch 2. Bern Verlag Hans Huber. Hautzinger, M., Bailer, M., Worall, H., & Keller, F. (1995). BDI: Beck-Depressions-Inventar Testhandbuch 2. Bern Verlag Hans Huber.
go back to reference Herrmann-Lingen, C., Buss, U., & Snaith, P. (1995). Hospital Anxiety and Depression Scale-Deutsche Version (HADS-D). Huber. Herrmann-Lingen, C., Buss, U., & Snaith, P. (1995). Hospital Anxiety and Depression Scale-Deutsche Version (HADS-D). Huber.
go back to reference Huang, F.-Y., Hsu, A.-L., Chao, Y.-P., Shang, C.M.-H., Tsai, J.-S., & Wu, C. W. (2021). Mindfulness-based cognitive therapy on bereavement grief: Alterations of resting-state network connectivity associate with changes of anxiety and mindfulness. Human Brain Mapping, 42(2), 510–520. https://doi.org/10.1002/hbm.25240CrossRefPubMed Huang, F.-Y., Hsu, A.-L., Chao, Y.-P., Shang, C.M.-H., Tsai, J.-S., & Wu, C. W. (2021). Mindfulness-based cognitive therapy on bereavement grief: Alterations of resting-state network connectivity associate with changes of anxiety and mindfulness. Human Brain Mapping, 42(2), 510–520. https://​doi.​org/​10.​1002/​hbm.​25240CrossRefPubMed
go back to reference Kabat-Zinn, J. (1994). Wherever you go, there you are: Mindfulness meditation in everyday life. Hyperion. Kabat-Zinn, J. (1994). Wherever you go, there you are: Mindfulness meditation in everyday life. Hyperion.
go back to reference Mendes, N., Oligschläger, S., Lauckner, M. E., Golchert, J., Huntenburg, J. M., Falkiewicz, M., Ellamil, M., Krause, S., Baczkowski, B. M., Cozatl, R., Osoianu, A., Kumral, D., Pool, J., Golz, L., Dreyer, M., Haueis, P., Jost, R., Kramarenko, Y., Engen, H., . . . Margulies, D. S. (2019). A functional connectome phenotyping dataset including cognitive state and personality measures. Scientific Data, 6(1), 180307. https://doi.org/10.1038/sdata.2018.307 Mendes, N., Oligschläger, S., Lauckner, M. E., Golchert, J., Huntenburg, J. M., Falkiewicz, M., Ellamil, M., Krause, S., Baczkowski, B. M., Cozatl, R., Osoianu, A., Kumral, D., Pool, J., Golz, L., Dreyer, M., Haueis, P., Jost, R., Kramarenko, Y., Engen, H., . . . Margulies, D. S. (2019). A functional connectome phenotyping dataset including cognitive state and personality measures. Scientific Data, 6(1), 180307. https://​doi.​org/​10.​1038/​sdata.​2018.​307
go back to reference Sip, V., Hashemi, M., Dickscheid, T., Amunts, K., Petkoski, S., & Jirsa, V. (2023). Characterization of regional differences in resting-state fMRI with a data-driven network model of brain dynamics. Science Advances, 9(11), eabq7547. https://doi.org/10.1126/sciadv.abq7547 Sip, V., Hashemi, M., Dickscheid, T., Amunts, K., Petkoski, S., & Jirsa, V. (2023). Characterization of regional differences in resting-state fMRI with a data-driven network model of brain dynamics. Science Advances, 9(11), eabq7547. https://​doi.​org/​10.​1126/​sciadv.​abq7547
go back to reference Spielberger, C. D., Gorsuch, R. L., & Lushene, R. E. (1970). The State-Trait Anxiety Inventory. Consulting Psychologists Press. Spielberger, C. D., Gorsuch, R. L., & Lushene, R. E. (1970). The State-Trait Anxiety Inventory. Consulting Psychologists Press.
go back to reference Yeo, B. T. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., Fischl, B., Liu, H., & Buckner, R. L. (2011). The organization of the human cerebral cortex estimated by intrinsic functional connectivity. Journal of Neurophysiology, 106(3), 1125–1165. https://doi.org/10.1152/jn.00338.2011CrossRefPubMed Yeo, B. T. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., Fischl, B., Liu, H., & Buckner, R. L. (2011). The organization of the human cerebral cortex estimated by intrinsic functional connectivity. Journal of Neurophysiology, 106(3), 1125–1165. https://​doi.​org/​10.​1152/​jn.​00338.​2011CrossRefPubMed
Metagegevens
Titel
Resting-State Functional Connectivity Associated with Non-Judgmental Awareness Predicted Multiple Measures of Negative Affect
Auteurs
Yi-Sheng Wong
Savannah Siew
Junhong Yu
Publicatiedatum
23-07-2024
Uitgeverij
Springer US
Gepubliceerd in
Mindfulness / Uitgave 8/2024
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI
https://doi.org/10.1007/s12671-024-02413-7