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Journal of Psychopathology and Behavioral Assessment

Gepubliceerd in:

28-04-2020

Response-to-Treatment for Comorbid Post-Traumatic Stress and Substance Use Disorders: the Value of Combining Person- and Variable-Centered Approaches

Auteurs: Nicholas P. Allan, Teresa López-Castro, Denise A. Hien, Santiago Papini, Therese K. Killeen, Daniel F. Gros, Lesia M. Ruglass, Emma Barrett, Sudie E. Back

Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment | Uitgave 4/2020

Abstract

Optimizing treatment for co-occurring post-traumatic stress disorder and substance use disorder (PTSD+SUD) is critically important. Whereas treatments have been designed that target PTSD+SUD with some success, these treatments do not benefit all. Data-driven approaches that combine person- and variable-centered methods, such as parallel process latent class growth analysis (PP-LCGA) can be used to identify response-to-treatment trajectories across both PTSD symptoms and substance use. The current study employed PP-LCGA separately in two randomized clinical trials (study 1 n = 81, Mean age = 40.4 years, SD = 10.7; study 2 n = 59, Mean age = 44.7 years, SD = 9.4) to examine PTSD symptom response and percentage of days using substances across treatment trials comparing Concurrent Treatment of PTSD and SUD using Prolonged Exposure and Relapse Prevention. Results revealed four PTSD+SUD profiles for study one and three PTSD+SUD profiles for study two. For PTSD symptoms, response trajectories could be broadly classified into treatment responders and non-responders across both studies. For substance use, response trajectories could be broadly classified into declining, moderately stable, and abstaining profiles. When considering PTSD symptoms and substance use trajectories together, profiles emerged that would have been missed had these treatment outcomes been considered separately.

vorige artikel Learning the Affective Value of Others in Schizophrenia: Examining the Role of Negative Symptoms and Cognitive Deficits

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Titel: Response-to-Treatment for Comorbid Post-Traumatic Stress and Substance Use Disorders: the Value of Combining Person- and Variable-Centered Approaches
Auteurs: Nicholas P. Allan
Teresa López-Castro
Denise A. Hien
Santiago Papini
Therese K. Killeen
Daniel F. Gros
Lesia M. Ruglass
Emma Barrett
Sudie E. Back
Publicatiedatum: 28-04-2020
Uitgeverij: Springer US
Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment / Uitgave 4/2020
Print ISSN: 0882-2689
Elektronisch ISSN: 1573-3505
DOI: https://doi.org/10.1007/s10862-020-09803-w

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