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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2015

01-05-2015 | Original Paper

Repetitive Behavior in Rubinstein–Taybi Syndrome: Parallels with Autism Spectrum Phenomenology

Auteurs: Jane Waite, Joanna Moss, Sarah R. Beck, Caroline Richards, Lisa Nelson, Kate Arron, Cheryl Burbidge, Katy Berg, Chris Oliver

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2015

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Abstract

Syndrome specific repetitive behavior profiles have been described previously. A detailed profile is absent for Rubinstein–Taybi syndrome (RTS). The Repetitive Behaviour Questionnaire and Social Communication Questionnaire were completed for children and adults with RTS (N = 87), Fragile-X (N = 196) and Down (N = 132) syndromes, and individuals reaching cut-off for autism spectrum disorder (N = 228). Total and matched group analyses were conducted. A phenotypic profile of repetitive behavior was found in RTS. The majority of behaviors in RTS were not associated with social-communication deficits or degree of disability. Repetitive behavior should be studied at a fine-grained level. A dissociation of the triad of impairments might be evident in RTS.
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1
The Autism Screening Questionnaire (ASQ) was used in the FXS group while the SCQ was used for the other groups. Item 20 (social chat) differed between the versions for nonverbal participants so to ensure consistency this item was treated as missing data and prorated for nonverbal participants by computing the mean score for other completed items within the communication subscale. The use of the prorated item did not alter the significance or direction of results.
 
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Metagegevens
Titel
Repetitive Behavior in Rubinstein–Taybi Syndrome: Parallels with Autism Spectrum Phenomenology
Auteurs
Jane Waite
Joanna Moss
Sarah R. Beck
Caroline Richards
Lisa Nelson
Kate Arron
Cheryl Burbidge
Katy Berg
Chris Oliver
Publicatiedatum
01-05-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2283-7

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