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18-08-2020 | Original Paper

Repetitive and Self-injurious Behaviors in Children with Cornelia de Lange Syndrome

Auteurs: Siddharth Srivastava, Bennett Clark, Colleen Landy-Schmitt, Elizabeth A. Offermann, Antonie D. Kline, Samuel T. Wilkinson, Marco A. Grados

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2021

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Abstract

Cornelia de Lange syndrome (CdLS) is associated with repetitive and self-injurious behaviors (RBs, SIB). Evaluating children with CdLS, this study: (1) characterizes the spectrum of RBs; (2) characterizes the impact and severity of RBs including SIB; (3) describes how age and adaptive functioning relate to RBs including SIB. Fifty children (5–17 years) with CdLS were assessed with Children’s Yale-Brown Obsessive Compulsive Scale Modified for PDD; Aberrant Behavior Checklist (ABC); Vineland Adaptive Behaviors Scales (VABS). All children had ≥ 1 type of RB; 44% had some form of SIB. 64% spent > 1 h/day displaying RBs. Lower VABS adaptive functioning was associated with higher stereotypy and SIB scores (ABC). In children with CdLS, RBs including SIB are common, impactful, and associated with lower adaptive functioning.
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Metagegevens
Titel
Repetitive and Self-injurious Behaviors in Children with Cornelia de Lange Syndrome
Auteurs
Siddharth Srivastava
Bennett Clark
Colleen Landy-Schmitt
Elizabeth A. Offermann
Antonie D. Kline
Samuel T. Wilkinson
Marco A. Grados
Publicatiedatum
18-08-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2021
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04617-x

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