Swipe om te navigeren naar een ander artikel
To assess the psychometric properties of the Greek Macular Disease-Dependent Quality of Life Questionnaire (MacDQoL).
The MacDQoL was translated in Greek and administered to 191 patients with neovascular age-related macular degeneration (AMD). To assess validity, all patients completed the Greek SF-12 health survey and underwent vision measurements. For test–retest reliability, a subset of twenty participants completed the MacDQoL twice, 2 weeks apart. Responsiveness was assessed on 102 patients who completed the MacDQoL at a follow-up visit, 1 year later. Rasch analysis was used to assess the Greek MacDQoL’s response category functioning, precision, unidimensionality, targeting and differential item functioning.
Internal and test–retest reliability of the average weighted impact (AWI) was 0.952 and 0.97, respectively. Test–retest reliability of MacDQoL items ranged from 0.78 to 0.99. Principal component analysis revealed three subscales (activities, embarrassment and family life), which were also confirmed by confirmatory factor analysis. Rasch analysis revealed poor functionality of response categories and that was resolved by collapsing response categories and using the impairment scores only. In terms of convergent validity, the AWI and revised MacDQoL scales showed significant correlations with SF-12 summary scales (ρ = 0.21–0.30) and vision assessments (ρ = 0.31–0.46). Poorer AMD-related QoL at 1-year follow-up was associated with deterioration in distance visual acuity and worse eye near visual acuity.
The Greek MacDQoL is a reliable, valid and sensitive to change in vision instrument for assessing AMD patients’ perceptions of QoL. However, Rasch analysis revealed that its multiplicative rating scale is flawed. Scientific measurement was restored with a number of revisions to the questionnaire.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Chang, T. S., Bressler, N. M., Fine, J. T., Dolan, C. M., Ward, J., Klesert, T. R., et al. (2007). Improved vision-related function after ranibizumab treatment of neovascular age-related macular degeneration: Results of a randomized clinical trial. Archives of Ophthalmology,125(11), 1460–1469. CrossRefPubMed
van Asten, F., Evers-Birkenkamp, K. U., van Lith-Verhoeven, J. J., de Jong-Hesse, Y., Hoppenreijs, V. P., Hommersom, R. F., et al. (2015). A prospective, observational, open-label, multicentre study to investigate the daily treatment practice of ranibizumab in patients with neovascular age-related macular degeneration. Acta Ophthalmologica,93(2), 126–133. CrossRefPubMed
Mitchell, J., Wolffsohn, J. S., Woodcock, A., Anderson, S. J., McMillan, C. V., Ffytche, T., et al. (2006). +Psychometric evaluation of the MacDQoL individualized measure of the impact of macular degeneration on quality of life. Health and Quality of Life Outcomes. doi: 10.1186/1477-7525-3-25. PubMedPubMedCentral
Wild, D., Grove, A., Martin, M., Eremenco, S., McElroy, S., Verjee-Lorenz, A., et al. (2005). Principles of good practice for the translation and cultural adaptation process for patient-reported outcomes (PRO) measures: Report of the ISPOR task force for translation and cultural adaptation. Value in Health,8(2), 94–104. CrossRefPubMed
Pelli, D. G., Robson, J. G., & Wilkins, A. J. (1988). The design of a new letter chart to measure contrast sensitivity. Clinical Vision Sciences,2, 187–199.
Yves, R. (2012). Lavaan: An R package for structural equation modeling. Journal of Statistical Software,48(2), 1–36.
Arditi, A., & Cagenello, R. (1993). On the statistical reliability of letter-chart visual acuity measurements. Investigative Ophthalmology and Visual Science,34(1), 120–129. PubMed
Bond, T. G., & Fox, C. M. (2015). Applying the Rasch model: Fundamental measurement in the human sciences (3rd ed.). New York: Taylor and Francis.
Chien, T. W. (2008). Repeated measure designs (time series) and Rasch. Rasch Measurement Transactions,22(3), 1171.
Hu, L., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling,6, 1–55. CrossRef
Abdelfattah, N. S., Amgad, M., Salama, A. A., Israel, M. E., Elhawary, G. A., Radwan, A. E., et al. (2014). Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt. International Journal of Ophthalmology,7(5), 891–897. PubMedPubMedCentral
- Reliability, validity and responsiveness of the Greek MacDQoL individualized measure of the impact of macular degeneration on quality of life
Theodoros P. Marakis
Klio I. Chatzistefanou
- Springer International Publishing