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03-06-2015 | Uitgave 11/2015

Reliability and construct validity of PROMIS^® measures for patients with heart failure who undergo heart transplant

Tijdschrift:: Quality of Life Research > Uitgave 11/2015

Auteurs:: Kathryn E. Flynn, Mary Amanda Dew, Li Lin, Maria Fawzy, Felicia L. Graham, Elizabeth A. Hahn, Ron D. Hays, Robert L. Kormos, Honghu Liu, Mary McNulty, Kevin P. Weinfurt

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Electronic supplementary material

The online version of this article (doi:10.1007/s11136-015-1010-y) contains supplementary material, which is available to authorized users.

Abstract

Purpose

To evaluate the reliability and construct validity of measures from the Patient-Reported Outcomes Measurement Information System^® (PROMIS^®) for patients with heart failure before and after heart transplantation.

Methods

We assessed reliability of the PROMIS short forms using Cronbach’s alpha and the average marginal reliability. To assess the construct validity of PROMIS computerized adaptive tests and short-form measures, we calculated Pearson product moment correlations between PROMIS measures of physical function, fatigue, depression, and social function and existing PRO measures of similar domains (i.e., convergent validity) as well as different domains (i.e., discriminate validity) in patients with heart failure awaiting heart transplant. We evaluated the responsiveness of these measures to change after heart transplant using effect sizes.

Results

Forty-eight patients were included in the analyses. Across the many domains examined, correlations between conceptually similar domains were larger than correlations between different domains of health, demonstrating construct validity. Health status improved substantially after heart transplant (standardized effect sizes, 0.63–1.24), demonstrating the responsiveness of the PROMIS measures. Scores from the computerized adaptive tests and the short forms were similar.

Conclusions

This study provides evidence for the reliability and construct validity (including responsiveness to change) of four PROMIS domains in patients with heart failure before and after heart transplant. PROMIS measures are a reasonable choice in this context and will facilitate comparisons across studies and health conditions.

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Titel: Reliability and construct validity of PROMIS® measures for patients with heart failure who undergo heart transplant
Auteurs:: Kathryn E. Flynn
Mary Amanda Dew
Li Lin
Maria Fawzy
Felicia L. Graham
Elizabeth A. Hahn
Ron D. Hays
Robert L. Kormos
Honghu Liu
Mary McNulty
Kevin P. Weinfurt
Publicatiedatum: 03-06-2015
DOI: https://doi.org/10.1007/s11136-015-1010-y
Uitgeverij: Springer International Publishing
Tijdschrift: Quality of Life Research An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation - An Official Journal of the International Society of Quality of Life Research
Uitgave 11/2015
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649

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Abstract

Purpose

Methods

Results

Conclusions

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