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Auditory hyper-reactivity is a common sensory-perceptual abnormality in autism spectrum disorders (ASD), which interrupts behavioral adaptation. We investigated acoustic startle response (ASR) modulations in 17 children with ASD and 27 with typical development (TD). Compared to TD, children with ASD had larger ASR magnitude to weak stimuli and more prolonged peak startle-latency. We could not find significant difference of prepulse inhibition (PPI) or habituation in ASD children compared to TD. However, habituation and PPI at 70-dB prepulses were negatively related to several subscales of Social Responsiveness Scale and the Strengths and Difficulties Questionnaire, when considering all children. Comprehensive investigation of ASR and its modulation might increase understanding of the neurophysiological impairments underlying ASD and other mental health problems in children.
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American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th rev ed.). Washington, DC: American Psychiatric Association.
Constantino, J. N., & Gruber, C. P. (2005). Social Responsiveness Scale (SRS). Los Angeles: Western Psychological Services.
Franklin, J. C., Bowker, K. B., & Blumenthal, T. D. (2009). Anxiety and prepulse inhibition of acoustic startle in a normative sample: The importance of signal-to-noise ratio. Personality and Individual Differences, 46, 369–373. CrossRef
Gomes, E., Pedroso, F. S., & Wagner, M. B. (2008). Auditory hypersensitivity in the autistic spectrum disorder. Pró-fono: Revista de Atualização Científica, 20, 279–284. CrossRef
Goodman, R., Ford, T., Corbin, T., & Meltzer, H. (2004). Using the strengths and difficulties questionnaire (SDQ) multi-informant algorithm to screen looked-after children for psychiatric disorders. European Child and Adolescent Psychiatry., 13(Suppl. 2), II25–II31. PubMed
Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217–250.
Lai, M.-C., Lombardo, M. V., & Baron-Cohen, S. (2014). Autism. The Lancet, 383(9920), 896–910. CrossRef
Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (2000). Autism diagnostic observation schedule. Los Angeles: Western Psychological Services.
Lord, C., Rutter, M., & Le Couteur, A. (1995). Autism diagnostic interview-revised (3rd ed.). Los Angeles: Western Psychological Services.
Moriwaki, A., & Kamio, Y. (2014). Normative data and psychometric properties of the strengths and difficulties questionnaire among Japanese school-aged children. Child and Adolescent Psychiatry and Mental Health. 21, 8(1):1. doi: 10.1186/1753-2000-8-1.
Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 921–929. CrossRefPubMed
Stiegler, L. N., & Davis, R. (2010). Understanding sound sensitivity in individuals with autism spectrum disorders. Focus on Autism and Other Developmental Disabilities, 25, 67–75. CrossRef
Takahashi, H., Iwase, M., Canuet, L., Yasuda, Y., Ohi, K., Fukumoto, M., et al. (2010). Relationship between prepulse inhibition of acoustic startle response and schizotypy in healthy Japanese subjects. Psychophysiology, 47, 831–837. PubMed
Takahashi, H., Rissling, A. J., Pascual-Marqui, R., Kirihara, K., Pela, M., Sprock, J., et al. (2013). Neural substrates of normal and impaired preattentive sensory discrimination in large cohorts of nonpsychiatric subjects and schizophrenia patients as indexed by MMN and P3a change detection responses. Neuroimage, 66, 594–603. CrossRefPubMed
Wechsler, D. (1991). Manual for the Wechsler intelligence scale for children, WISC III (3rd ed.). New York: The Psychological Corporation.
- Relationship of the Acoustic Startle Response and Its Modulation to Emotional and Behavioral Problems in Typical Development Children and Those with Autism Spectrum Disorders
- Springer US