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Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2014

01-11-2014 | Original Paper

Rates and Predictors of Adherence to Psychotropic Medications in Children with Autism Spectrum Disorders

Auteurs: Sarah L. Logan, Laura Carpenter, R. Scott Leslie, Kelly S. Hunt, Elizabeth Garrett-Mayer, Jane Charles, Joyce S. Nicholas

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2014

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Abstract

Medication adherence in children is poor, particularly among those with chronic or mental health disorders. However, adherence has not been fully assessed in autism spectrum disorders (ASDs). The validated proportion of days covered method was used to quantify adherence to psychotropic medication in Medicaid-eligible children who met diagnostic criteria for ASD between 2000 and 2008 (N = 628). Among children prescribed attention deficit hyperactivity disorder (ADHD) medications, antidepressants, or antipsychotics, 44, 40 and 52 % were adherent respectively. Aggressive behaviors and abnormalities in eating, drinking, and/or sleeping, co-occurring ADHD, and the Medication Regimen Complexity Index were the most significant predictors of adherence rather than demographics or core deficits of ASD. Identifying barriers to adherence in ASD may ultimately lead to improved treatment outcomes.
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Literatuur
go back to reference Akincigil, A., Bowblis, J., et al. (2007). Adherence to antidepressant treatment among privately insured patients diagnosed with depression. Medical Care, 45(4), 363–369. PubMedPubMedCentralCrossRef Akincigil, A., Bowblis, J., et al. (2007). Adherence to antidepressant treatment among privately insured patients diagnosed with depression. Medical Care, 45(4), 363–369. PubMedPubMedCentralCrossRef
go back to reference Allison, P. (2001). Logistic regression using the SAS system: Theory and application (p. 48). Cary: Wiley-SAS. Allison, P. (2001). Logistic regression using the SAS system: Theory and application (p. 48). Cary: Wiley-SAS.
go back to reference Aman, M. G., Lam, K. S. L., et al. (2005). Medication patterns in patients with autism: Temporal, regional, and demographic influences. Journal of Child and Adolescent Psychopharmacology, 15(1), 116–126. PubMedCrossRef Aman, M. G., Lam, K. S. L., et al. (2005). Medication patterns in patients with autism: Temporal, regional, and demographic influences. Journal of Child and Adolescent Psychopharmacology, 15(1), 116–126. PubMedCrossRef
go back to reference American Psychiatric Association (APA). (2000). Diagnostic and statistical manual of mental disorder, fourth edition, text revision. Washington, DC: American Psychiatric Association. American Psychiatric Association (APA). (2000). Diagnostic and statistical manual of mental disorder, fourth edition, text revision. Washington, DC: American Psychiatric Association.
go back to reference Arney, J., Street, R. J., et al. (2012). Factors shaping physicians’ willingness to accomodate medication requests. Evaluations & the Health Professions [Epub ahead of print]. Arney, J., Street, R. J., et al. (2012). Factors shaping physicians’ willingness to accomodate medication requests. Evaluations & the Health Professions [Epub ahead of print].
go back to reference Bilder, D., Pinborough-Zimmerman, J., Miller, J., & McMahon, W. (2009). Prenatal, perinatal, and neonatal factors associated with autism spectrum disorders. Pediatrics, 123(5), 1293–1300. PubMedCrossRef Bilder, D., Pinborough-Zimmerman, J., Miller, J., & McMahon, W. (2009). Prenatal, perinatal, and neonatal factors associated with autism spectrum disorders. Pediatrics, 123(5), 1293–1300. PubMedCrossRef
go back to reference Bussing, R., et al. (2003). Parental explanatory models of ADHD: Gender and cultural variation. Social Psychiatry and Psychiatric Epidemiology, 38(10), 563–575. PubMedCrossRef Bussing, R., et al. (2003). Parental explanatory models of ADHD: Gender and cultural variation. Social Psychiatry and Psychiatric Epidemiology, 38(10), 563–575. PubMedCrossRef
go back to reference Canas, F., Alptekin, K., et al. (2013). Improving treatment adherence in your patients with Schizophrenia: The STAY initiative. Clinical Drug Investigation, 33(2), 97–107. Canas, F., Alptekin, K., et al. (2013). Improving treatment adherence in your patients with Schizophrenia: The STAY initiative. Clinical Drug Investigation, 33(2), 97–107.
go back to reference CDC. (2012). Prevalence of autism spectrum disorders—Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Morbidity and Mortality Weekly Report, 61(SS03), 1–19. CDC. (2012). Prevalence of autism spectrum disorders—Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Morbidity and Mortality Weekly Report, 61(SS03), 1–19.
go back to reference Chacko, A., Neworn, J., et al. (2010). Improving medication adherence in chronic pediatric health conditions: A focus on ADHD in youth. Current Pharmaceutical Design, 16, 2416–2423. PubMedCrossRef Chacko, A., Neworn, J., et al. (2010). Improving medication adherence in chronic pediatric health conditions: A focus on ADHD in youth. Current Pharmaceutical Design, 16, 2416–2423. PubMedCrossRef
go back to reference Chavira, D., et al. (2003). Parental opinions regarding treatment for social anxiety disorder in youth. Journal of Developmental and Behavioral, 24(5), 315–322. Chavira, D., et al. (2003). Parental opinions regarding treatment for social anxiety disorder in youth. Journal of Developmental and Behavioral, 24(5), 315–322.
go back to reference Ciechanowski, P., Katon, W., et al. (2000). Depression and diabetes: Impact of depressives symptoms on adherence, function, and costs. Archives of Internal Medicine, 27, 3278–3285. CrossRef Ciechanowski, P., Katon, W., et al. (2000). Depression and diabetes: Impact of depressives symptoms on adherence, function, and costs. Archives of Internal Medicine, 27, 3278–3285. CrossRef
go back to reference Coury, D. (2011). Very little high-quality evidence to support most medications for children with autism spectrum disorders. The Journal of Pediatrics, 159(5), 872–873. PubMedCrossRef Coury, D. (2011). Very little high-quality evidence to support most medications for children with autism spectrum disorders. The Journal of Pediatrics, 159(5), 872–873. PubMedCrossRef
go back to reference Coury, D., Anagnostou, E., et al. (2012). Use of psychotropic medication in children and adolescents with autism spectrum disorders. Pediatrics, 130(S69), S69–S76. PubMedCrossRef Coury, D., Anagnostou, E., et al. (2012). Use of psychotropic medication in children and adolescents with autism spectrum disorders. Pediatrics, 130(S69), S69–S76. PubMedCrossRef
go back to reference Cramer, J., et al. (2007). Medication compliance and persistence: terminology and definitions. Value in Health. The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Medication Compliance and Persistence Work Group, 11, 44–47. Cramer, J., et al. (2007). Medication compliance and persistence: terminology and definitions. Value in Health. The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Medication Compliance and Persistence Work Group, 11, 44–47.
go back to reference Dean, A. J., Wragg, J., et al. (2011). Predictors of medication adherence in children receiving psychotropic medication. Journal of Paediatrics and Child Health, 47(6), 350–355. PubMedCrossRef Dean, A. J., Wragg, J., et al. (2011). Predictors of medication adherence in children receiving psychotropic medication. Journal of Paediatrics and Child Health, 47(6), 350–355. PubMedCrossRef
go back to reference Dilorio, C., Yeager, K., Shafer, P. O., Letz, R., Henry, T., Schomer, D. L., et al. (2003). The epilepsy medication and treatment complexity index: Reliability and validity testing. Journal of Neuroscience Nursing, 35(3), 155–162. CrossRef Dilorio, C., Yeager, K., Shafer, P. O., Letz, R., Henry, T., Schomer, D. L., et al. (2003). The epilepsy medication and treatment complexity index: Reliability and validity testing. Journal of Neuroscience Nursing, 35(3), 155–162. CrossRef
go back to reference Donohue, J. M., Berndt, E. R., et al. (2004). Effects of pharmaceutical promotion on adherence to the treatment guidelines for depression. Medical Care, 42(12), 1176–1185. PubMedCrossRef Donohue, J. M., Berndt, E. R., et al. (2004). Effects of pharmaceutical promotion on adherence to the treatment guidelines for depression. Medical Care, 42(12), 1176–1185. PubMedCrossRef
go back to reference Donohue, J. M., Cevasco, M., et al. (2007). A decade of direct-to-consumer advertising of prescription drugs. New England Journal of Medicine, 357(7), 673–681. PubMedCrossRef Donohue, J. M., Cevasco, M., et al. (2007). A decade of direct-to-consumer advertising of prescription drugs. New England Journal of Medicine, 357(7), 673–681. PubMedCrossRef
go back to reference dosReis, S., Zito, J. M., et al. (2005). Multiple psychotropic medication use for youths: A two-state comparison. Journal of Child and Adolescent Psychopharmacology, 15(1), 68–77. PubMedCrossRef dosReis, S., Zito, J. M., et al. (2005). Multiple psychotropic medication use for youths: A two-state comparison. Journal of Child and Adolescent Psychopharmacology, 15(1), 68–77. PubMedCrossRef
go back to reference Dove, D., Warren, Z., et al. (2012). Medications for adolescents and young adults with autism spectrum disorders: A systematic review. Pediatrics, 130(4), 717–726. PubMedPubMedCentralCrossRef Dove, D., Warren, Z., et al. (2012). Medications for adolescents and young adults with autism spectrum disorders: A systematic review. Pediatrics, 130(4), 717–726. PubMedPubMedCentralCrossRef
go back to reference Drotar, D., Neff-Greenley, R., et al. (2007). Adherence to pharmacological treatment for juvenile bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 46(7), 831–839. PubMedCrossRef Drotar, D., Neff-Greenley, R., et al. (2007). Adherence to pharmacological treatment for juvenile bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 46(7), 831–839. PubMedCrossRef
go back to reference Durkin, M., Maenner, M., Meaney, F., Levy, S. E., DiGuiseppi, C., Nicholas, J. S., et al. (2010). Socioeconomic inequality in the prevalence of autism spectrum disorder: Evidence from a US cross-sectional study. PLoS ONE, e11511. Durkin, M., Maenner, M., Meaney, F., Levy, S. E., DiGuiseppi, C., Nicholas, J. S., et al. (2010). Socioeconomic inequality in the prevalence of autism spectrum disorder: Evidence from a US cross-sectional study. PLoS ONE, e11511.
go back to reference Durkin, M. S., Maenner, M., Newschaffer, C. J., Lee, L. C., Cunniff, C. M., Daniels, J. L., et al. (2008). Advanced parental age and the risk of autism spectrum disorder. American Journal of Epidemiology, 168(11), 1268–1276. PubMedPubMedCentralCrossRef Durkin, M. S., Maenner, M., Newschaffer, C. J., Lee, L. C., Cunniff, C. M., Daniels, J. L., et al. (2008). Advanced parental age and the risk of autism spectrum disorder. American Journal of Epidemiology, 168(11), 1268–1276. PubMedPubMedCentralCrossRef
go back to reference Esbensen, A., Greenberg, J., et al. (2009). A longitudinal investigation of psychotropic and non-psychotropic medication use among adolescents and adults with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(9), 1339–1349. Esbensen, A., Greenberg, J., et al. (2009). A longitudinal investigation of psychotropic and non-psychotropic medication use among adolescents and adults with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(9), 1339–1349.
go back to reference Farley, J., Hansen, R., et al. (2012). Antipsychotic adherence and its correlation to health outcomes for chronic comorbid conditions. The Primary Care Companion to CNS Disorders. doi: 10.​4088/​PCC.​11m01324. Farley, J., Hansen, R., et al. (2012). Antipsychotic adherence and its correlation to health outcomes for chronic comorbid conditions. The Primary Care Companion to CNS Disorders. doi: 10.​4088/​PCC.​11m01324.
go back to reference Faught, E., Duh, M., et al. (2008). Nonadherence to antiepileptic drugs and increased mortality findings from the RANSOM Study. Neurology, 17(20), 1572–1578. CrossRef Faught, E., Duh, M., et al. (2008). Nonadherence to antiepileptic drugs and increased mortality findings from the RANSOM Study. Neurology, 17(20), 1572–1578. CrossRef
go back to reference Fontanella, C., Bridge, J., et al. (2011). Factors associated with antidepressant adherence for Medicaid-eligible enrolled children and adolescents. Annals of Pharmacotherapy, 45, 898–909. PubMedCrossRef Fontanella, C., Bridge, J., et al. (2011). Factors associated with antidepressant adherence for Medicaid-eligible enrolled children and adolescents. Annals of Pharmacotherapy, 45, 898–909. PubMedCrossRef
go back to reference Friedman, L., Furberg, C., et al. (2010). Fundamentals of clinical trials. New York, Heidelberg: Springer, 251–267. CrossRef Friedman, L., Furberg, C., et al. (2010). Fundamentals of clinical trials. New York, Heidelberg: Springer, 251–267. CrossRef
go back to reference Gau, S., Chen, S., et al. (2008). National survey of adherence, efficacy, and side effects of methylphenidate in children with attention-deficit/hyperactivity disorder in Taiwan. Journal of Clinical Psychiatry, 69(1), 131–140. PubMedCrossRef Gau, S., Chen, S., et al. (2008). National survey of adherence, efficacy, and side effects of methylphenidate in children with attention-deficit/hyperactivity disorder in Taiwan. Journal of Clinical Psychiatry, 69(1), 131–140. PubMedCrossRef
go back to reference Gau, S., Shen, H., et al. (2006). Determinants of adherence to methylphenidate and the impact of poor adherence on maternal and family measures. Journal of Child & Adolescent Psychopharmacology, 16, 286–297. CrossRef Gau, S., Shen, H., et al. (2006). Determinants of adherence to methylphenidate and the impact of poor adherence on maternal and family measures. Journal of Child & Adolescent Psychopharmacology, 16, 286–297. CrossRef
go back to reference George, J., Phun, Y. T., et al. (2004). Development and validation of the Medication Regimen Complexity Index. The Annals of Pharmacotherapy, 38(9), 1369–1376. PubMedCrossRef George, J., Phun, Y. T., et al. (2004). Development and validation of the Medication Regimen Complexity Index. The Annals of Pharmacotherapy, 38(9), 1369–1376. PubMedCrossRef
go back to reference Giarelli, E., Wiggins, L., Rice, C. E., Levy, S. E., Kirby, R. S., Pinto-Martin, J., et al. (2010). Sex differences in the evaluation and diagnosis of autism spectrum disorders among children. Disability and Health Journal, 3(2), 107–116. PubMedCrossRef Giarelli, E., Wiggins, L., Rice, C. E., Levy, S. E., Kirby, R. S., Pinto-Martin, J., et al. (2010). Sex differences in the evaluation and diagnosis of autism spectrum disorders among children. Disability and Health Journal, 3(2), 107–116. PubMedCrossRef
go back to reference Gupta, K., & Horne, R. (2001). The influence of health beliefs on the presentation and consultation outcome in patients with chemical sensitivities. Journal of Psychosomatic Research, 50, 131–137. PubMedCrossRef Gupta, K., & Horne, R. (2001). The influence of health beliefs on the presentation and consultation outcome in patients with chemical sensitivities. Journal of Psychosomatic Research, 50, 131–137. PubMedCrossRef
go back to reference Hack, S., & Chow, B. (2001). Pediatric psychotropic medication compliance: A literature review and research-based suggestions for improving treatment compliance. Journal of Child and Adolescent Psychopharmacology, 11(1), 59–67. PubMedCrossRef Hack, S., & Chow, B. (2001). Pediatric psychotropic medication compliance: A literature review and research-based suggestions for improving treatment compliance. Journal of Child and Adolescent Psychopharmacology, 11(1), 59–67. PubMedCrossRef
go back to reference Hamrin, V., McCarthy, E., et al. (2010). Pediatric psychotropic medication initiation and adherence: A literature review based on social exchange theory. Journal of Child and Adolescent Psychiatric Nursing, 23(3), 151–172. PubMedCrossRef Hamrin, V., McCarthy, E., et al. (2010). Pediatric psychotropic medication initiation and adherence: A literature review based on social exchange theory. Journal of Child and Adolescent Psychiatric Nursing, 23(3), 151–172. PubMedCrossRef
go back to reference Handen, B., Johnson, C., et al. (2011). Safety and efficacy of donepezil in children and adolescents with autism: Neuropsychological measures. Journal of Child and Adolescent Psychopharmacology, 21(1), 43–50. PubMedPubMedCentralCrossRef Handen, B., Johnson, C., et al. (2011). Safety and efficacy of donepezil in children and adolescents with autism: Neuropsychological measures. Journal of Child and Adolescent Psychopharmacology, 21(1), 43–50. PubMedPubMedCentralCrossRef
go back to reference Hansen, R., Chen, S., et al. (2010). Relationship of pharmaceutical promotion to antidepressant switching and adherence: A retrospective cohort study. Psychiatric Services, 61(12), 1232–1238. PubMedCrossRef Hansen, R., Chen, S., et al. (2010). Relationship of pharmaceutical promotion to antidepressant switching and adherence: A retrospective cohort study. Psychiatric Services, 61(12), 1232–1238. PubMedCrossRef
go back to reference Hastie, T., Tibshirani, R., et al. (2009). The elements of statistical learning: Data mining, inference, and prediction (2nd ed.). New York: Springer. Hastie, T., Tibshirani, R., et al. (2009). The elements of statistical learning: Data mining, inference, and prediction (2nd ed.). New York: Springer.
go back to reference Horne, R., Hankins, M., et al. (2001). The satisfaction with information about medicines scale (SIMS): A new measurement tool for audit and research. Quality in Health Care, 10, 135–140. PubMedPubMedCentralCrossRef Horne, R., Hankins, M., et al. (2001). The satisfaction with information about medicines scale (SIMS): A new measurement tool for audit and research. Quality in Health Care, 10, 135–140. PubMedPubMedCentralCrossRef
go back to reference Horne, R., & Weinman, J. (1999). Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. Journal of Psychosomatic Research, 47, 555–567. PubMedCrossRef Horne, R., & Weinman, J. (1999). Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. Journal of Psychosomatic Research, 47, 555–567. PubMedCrossRef
go back to reference Hudson, J., Miller, G., et al. (2007). Explaining racial and ethnic differences in children’s use of stimulant medications. Medical Care, 45(11), 1068–1075. PubMedCrossRef Hudson, J., Miller, G., et al. (2007). Explaining racial and ethnic differences in children’s use of stimulant medications. Medical Care, 45(11), 1068–1075. PubMedCrossRef
go back to reference Joshi, G., Petty, C., et al. (2010). The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: A large comparative study of a psychiatrically referred population. Journal of Autism and Developmental Disorders, 40(11), 1361–1370. PubMedCrossRef Joshi, G., Petty, C., et al. (2010). The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: A large comparative study of a psychiatrically referred population. Journal of Autism and Developmental Disorders, 40(11), 1361–1370. PubMedCrossRef
go back to reference Kalkbrenner, A. E., Daniels, J., Chen, J. C., Poole, C., Emch, M., & Morrissey, J. (2010). Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8. Epidemiology, 21(5), 631–641. PubMedPubMedCentralCrossRef Kalkbrenner, A. E., Daniels, J., Chen, J. C., Poole, C., Emch, M., & Morrissey, J. (2010). Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8. Epidemiology, 21(5), 631–641. PubMedPubMedCentralCrossRef
go back to reference Karve, S., Cleves, M., Helm, M., Hudson, T. J., West, D. S., & Martin, B. C. (2008). An empirical basis for standardizing adherence measures derived from administrative claims data among diabetic patients. Medical Care, 46(11), 25–33. CrossRef Karve, S., Cleves, M., Helm, M., Hudson, T. J., West, D. S., & Martin, B. C. (2008). An empirical basis for standardizing adherence measures derived from administrative claims data among diabetic patients. Medical Care, 46(11), 25–33. CrossRef
go back to reference Karve, S., Cleves, M., Helm, M., Hudson, T. J., West, D. S., & Martin, B. C. (2009a). Good and poor adherence: Optimal cut-point for adherence measures using administrative claims data. Current Medical Research and Opinion, 25(9), 2302–2310. CrossRef Karve, S., Cleves, M., Helm, M., Hudson, T. J., West, D. S., & Martin, B. C. (2009a). Good and poor adherence: Optimal cut-point for adherence measures using administrative claims data. Current Medical Research and Opinion, 25(9), 2302–2310. CrossRef
go back to reference Karve, S., Cleves, M., et al. (2009b). Prospective validation of eight different adherence measures for use with administrative claims data among patients with schizophrenia. Value Health, 12(6), 989–995. PubMedCrossRef Karve, S., Cleves, M., et al. (2009b). Prospective validation of eight different adherence measures for use with administrative claims data among patients with schizophrenia. Value Health, 12(6), 989–995. PubMedCrossRef
go back to reference Kelley, S. O. (1988). Measurement of the complexity of medication regimens of the elderly. University of Missouri-Columbia. pp. 23–58. Kelley, S. O. (1988). Measurement of the complexity of medication regimens of the elderly. University of Missouri-Columbia. pp. 23–58.
go back to reference King, L., Nicholas, J., et al. (2008). Characteristics of autism spectrum disorders over time, surveillance results from children born between 1992 and 2002. AEP, 18(9), 724–725. King, L., Nicholas, J., et al. (2008). Characteristics of autism spectrum disorders over time, surveillance results from children born between 1992 and 2002. AEP, 18(9), 724–725.
go back to reference Lazaratou, H., Anagnostopoulos, D., et al. (2007). Parental attitudes and opinions on the use of psychotropic medication in mental disorders of childhood. Annals of General Psychiatry, 6(32). doi: 10.​1186/​1744-859X-6-32. Lazaratou, H., Anagnostopoulos, D., et al. (2007). Parental attitudes and opinions on the use of psychotropic medication in mental disorders of childhood. Annals of General Psychiatry, 6(32). doi: 10.​1186/​1744-859X-6-32.
go back to reference Leslie, R. S., Gwadry-Sridhar, F., et al. (2008). Calculating medication compliance, adherence, and persistence in administrative pharmacy claims databases. Pharmaceutical Programming, 1(1), 13–19. CrossRef Leslie, R. S., Gwadry-Sridhar, F., et al. (2008). Calculating medication compliance, adherence, and persistence in administrative pharmacy claims databases. Pharmaceutical Programming, 1(1), 13–19. CrossRef
go back to reference Levy, S., Giarelli, E., et al. (2010). Autism spectrum disorder and co-occurring developmental, psychiatric, medical conditions among children in multiple populations of the United States. Journal of Developmental and Behavioral Pediatrics, 31, 267–275. Levy, S., Giarelli, E., et al. (2010). Autism spectrum disorder and co-occurring developmental, psychiatric, medical conditions among children in multiple populations of the United States. Journal of Developmental and Behavioral Pediatrics, 31, 267–275.
go back to reference Logan, S., Nicholas, J., et al. (2012). High prescription drug use and associated costs among Medicaid-eligible children with autism spectrum disorders identified by a population-based surveillance network. Annals of Epidemiology, 22(1), 1–8. PubMedPubMedCentralCrossRef Logan, S., Nicholas, J., et al. (2012). High prescription drug use and associated costs among Medicaid-eligible children with autism spectrum disorders identified by a population-based surveillance network. Annals of Epidemiology, 22(1), 1–8. PubMedPubMedCentralCrossRef
go back to reference Mandell, D. S., Morales, K. H., et al. (2008). Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics, 121(3), e441–e448. PubMedPubMedCentralCrossRef Mandell, D. S., Morales, K. H., et al. (2008). Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics, 121(3), e441–e448. PubMedPubMedCentralCrossRef
go back to reference Mandell, D., Wiggins, L., Carpenter, L., Daniels, J., DiGuiseppi, C., Durkin, M., et al. (2009). Racial/ethnic disparities in the identification of children with autism spectrum disorders. American Journal of Public Health, 99(3), 493–498. PubMedPubMedCentralCrossRef Mandell, D., Wiggins, L., Carpenter, L., Daniels, J., DiGuiseppi, C., Durkin, M., et al. (2009). Racial/ethnic disparities in the identification of children with autism spectrum disorders. American Journal of Public Health, 99(3), 493–498. PubMedPubMedCentralCrossRef
go back to reference Marcus, S. (2011). Stimulant adherence and academic performance in urban youth with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 50(5), 480–489. Marcus, S. (2011). Stimulant adherence and academic performance in urban youth with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 50(5), 480–489.
go back to reference Martin, B., Wiley-Exley, E., et al. (2009). Contrasting measures of adherence with simple drug use, medication switching, and therapeutic duplication. Annals of Pharmacotherapy, 43(1), 36–44. PubMedCrossRef Martin, B., Wiley-Exley, E., et al. (2009). Contrasting measures of adherence with simple drug use, medication switching, and therapeutic duplication. Annals of Pharmacotherapy, 43(1), 36–44. PubMedCrossRef
go back to reference Martin, S., Wolters, P., Calabrese, S. K., Toledo-Tamula, M. A., Wood, L. V., Roby, G., et al. (2007). The antiretroviral regimen complexity index: A novel method of quantifying regimen complexity. Journal of Acquired Immune Deficiency Syndromes, 15(45), 535–544. CrossRef Martin, S., Wolters, P., Calabrese, S. K., Toledo-Tamula, M. A., Wood, L. V., Roby, G., et al. (2007). The antiretroviral regimen complexity index: A novel method of quantifying regimen complexity. Journal of Acquired Immune Deficiency Syndromes, 15(45), 535–544. CrossRef
go back to reference Matson, J. L., & Nebel-Schwalm, M. S. (2007). Comorbid psychopathology with autism spectrum disorder in children: An overview. Research in Developmental Disabilities, 28(4), 341–352. PubMedCrossRef Matson, J. L., & Nebel-Schwalm, M. S. (2007). Comorbid psychopathology with autism spectrum disorder in children: An overview. Research in Developmental Disabilities, 28(4), 341–352. PubMedCrossRef
go back to reference McPheeter, M., Warren, Z., et al. (2011). A systematic review of medical treatments for children with autism spectrum disorders. Pediatrics, 127(4), e1312–e1321. CrossRef McPheeter, M., Warren, Z., et al. (2011). A systematic review of medical treatments for children with autism spectrum disorders. Pediatrics, 127(4), e1312–e1321. CrossRef
go back to reference Meltzer, H. Y., Lindenmayer, J. P., Kwentus, J., Share, D. B., Johnson, R., & Jayathilake, K. (2014). A six month randomized controlled trial of long acting injectable risperidone 50 and 100 mg in treatment resistant schizophrenia. Schizophrenia Research, 154(1–3), 14–22. doi: 10.​1016/​j.​schres.​2014.​02.​15. Meltzer, H. Y., Lindenmayer, J. P., Kwentus, J., Share, D. B., Johnson, R., & Jayathilake, K. (2014). A six month randomized controlled trial of long acting injectable risperidone 50 and 100 mg in treatment resistant schizophrenia. Schizophrenia Research, 154(1–3), 14–22. doi: 10.​1016/​j.​schres.​2014.​02.​15.
go back to reference Ming, X., Brimacombe, M., et al. (2008). Autism spectrum disorders: Concurrent clinical disorders. Journal of Child Neurology, 23(1), 6–13. Ming, X., Brimacombe, M., et al. (2008). Autism spectrum disorders: Concurrent clinical disorders. Journal of Child Neurology, 23(1), 6–13.
go back to reference Mire, S., Nowell, K., Kubiszyn, T., & Goin-Kochel, R. (2013). Psychotropic medication use among children with autism spectrum disorders within the Simons Simplex Collection: Are core features of autism spectrum disorder related? Autism, 18(3). doi: 10.​1177/​1362361313498518​. Mire, S., Nowell, K., Kubiszyn, T., & Goin-Kochel, R. (2013). Psychotropic medication use among children with autism spectrum disorders within the Simons Simplex Collection: Are core features of autism spectrum disorder related? Autism, 18(3). doi: 10.​1177/​1362361313498518​.
go back to reference Mitchell, W., Scheeier, L., et al. (2000). Adherence to treatment in children with epilepsy: Who follows “doctor’s orders?”. Epilepsia, 41(12), 616–625. Mitchell, W., Scheeier, L., et al. (2000). Adherence to treatment in children with epilepsy: Who follows “doctor’s orders?”. Epilepsia, 41(12), 616–625.
go back to reference Moore, T., & Symons, F. (2009). Adherence to behavioral and medical treatment recommendations by parents of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(8), 1173–1184. PubMedCrossRef Moore, T., & Symons, F. (2009). Adherence to behavioral and medical treatment recommendations by parents of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39(8), 1173–1184. PubMedCrossRef
go back to reference Muir, A., Sanders, L., Wilkinson, W., & Schmader, K. (2001). Reducing medication regimen complexity: A controlled trial. Journal of General Internal Medicine, 16(2), 77–82. PubMedPubMedCentralCrossRef Muir, A., Sanders, L., Wilkinson, W., & Schmader, K. (2001). Reducing medication regimen complexity: A controlled trial. Journal of General Internal Medicine, 16(2), 77–82. PubMedPubMedCentralCrossRef
go back to reference Myers, S. M. (2007). The status of pharmacotherapy for autism spectrum disorders. Expert Opinion on Pharmacotherapy, 8(11), 1579–1603. PubMedCrossRef Myers, S. M. (2007). The status of pharmacotherapy for autism spectrum disorders. Expert Opinion on Pharmacotherapy, 8(11), 1579–1603. PubMedCrossRef
go back to reference Myers, S. M., Johnson, C. P., et al. (2007). Management of children with autism spectrum disorders. Pediatrics, 120(5), 1162–1182. PubMedCrossRef Myers, S. M., Johnson, C. P., et al. (2007). Management of children with autism spectrum disorders. Pediatrics, 120(5), 1162–1182. PubMedCrossRef
go back to reference Nicholas, J., Carpenter, L., King, L., Jenner, W., & Charles, J. (2009). Autism spectrum disorders in preschool-aged children: Prevalence and comparison to a school-aged population. Annals of Epidemiology, 19(11), 808–814. PubMedCrossRef Nicholas, J., Carpenter, L., King, L., Jenner, W., & Charles, J. (2009). Autism spectrum disorders in preschool-aged children: Prevalence and comparison to a school-aged population. Annals of Epidemiology, 19(11), 808–814. PubMedCrossRef
go back to reference Nicholas, J., Carpenter, L., et al. (2012). Completeness of case ascertainment for surveillance of autism spectrum disorders using the autism developmental disabilities monitoring network methodology. Disability and Health Journal, 5(3), 185–189. PubMedPubMedCentralCrossRef Nicholas, J., Carpenter, L., et al. (2012). Completeness of case ascertainment for surveillance of autism spectrum disorders using the autism developmental disabilities monitoring network methodology. Disability and Health Journal, 5(3), 185–189. PubMedPubMedCentralCrossRef
go back to reference Nicholas, J., Charles, J., Carpenter, L., King, L., Jenner, W., & Spratt, E. (2008). Prevalence and characteristics of children with autism-spectrum disorders. Annals of Epidemiology, 18(2), 130–136. PubMedCrossRef Nicholas, J., Charles, J., Carpenter, L., King, L., Jenner, W., & Spratt, E. (2008). Prevalence and characteristics of children with autism-spectrum disorders. Annals of Epidemiology, 18(2), 130–136. PubMedCrossRef
go back to reference Nicolson, R., Craven-Thuss, B., et al. (2006). A prospective, open-label trial of galantamine in autistic disorder. Journal of Child and Adolescent Psychopharmacology, 16(5), 621–629. PubMedCrossRef Nicolson, R., Craven-Thuss, B., et al. (2006). A prospective, open-label trial of galantamine in autistic disorder. Journal of Child and Adolescent Psychopharmacology, 16(5), 621–629. PubMedCrossRef
go back to reference OARC. (2012). Analysis report: The global landscape of autism research. Office of Autism Research Coordination (OARC). National Institute of Mental Health. Thomas Reuters, Interagency Autism Coordinating Committee (IACC). OARC. (2012). Analysis report: The global landscape of autism research. Office of Autism Research Coordination (OARC). National Institute of Mental Health. Thomas Reuters, Interagency Autism Coordinating Committee (IACC).
go back to reference Olaniyan, O., dosReis, R., et al. (2007). Community perspectives of childhood behavioral problems and ADHD among African American parents. Ambulatory Pragmatics, 7(3), 226–231. Olaniyan, O., dosReis, R., et al. (2007). Community perspectives of childhood behavioral problems and ADHD among African American parents. Ambulatory Pragmatics, 7(3), 226–231.
go back to reference Oswald, D. P., & Sonenklar, N. A. (2007). Medication use among children with autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology, 17(3), 348–355. PubMedCrossRef Oswald, D. P., & Sonenklar, N. A. (2007). Medication use among children with autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology, 17(3), 348–355. PubMedCrossRef
go back to reference Patel, N., DelBello, M., et al. (2005). Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 16(6), 938–946. CrossRef Patel, N., DelBello, M., et al. (2005). Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorder. Journal of Child and Adolescent Psychopharmacology, 16(6), 938–946. CrossRef
go back to reference Pinborough-Zimmerman, J., Bilder, D., Satterfield, R., Hossain, S., & McMahon, W. (2009). The impact of surveillance method and record source on autism prevalence: Collaboration with utah maternal and child health programs. Maternal and Child Health Journal, 14(3), 392–400. PubMedCrossRef Pinborough-Zimmerman, J., Bilder, D., Satterfield, R., Hossain, S., & McMahon, W. (2009). The impact of surveillance method and record source on autism prevalence: Collaboration with utah maternal and child health programs. Maternal and Child Health Journal, 14(3), 392–400. PubMedCrossRef
go back to reference Powell, K. C., Van Naarden Braun, K., Singh, R. H., Shapira, S. K., Olney, R. S., & Yeargin-Allsopp, M. (2010). Prevalence of developmental disabilities and receipt of special education services among children with an inborn error of metabolism. Pediatrics, 156, 420–426. CrossRef Powell, K. C., Van Naarden Braun, K., Singh, R. H., Shapira, S. K., Olney, R. S., & Yeargin-Allsopp, M. (2010). Prevalence of developmental disabilities and receipt of special education services among children with an inborn error of metabolism. Pediatrics, 156, 420–426. CrossRef
go back to reference Radigan, M., Lannon, P., et al. (2005). Medication patterns for attention deficit hyperactivity disorder and comorbid psychiatric conditions in a low-income population. Journal of Child and Adolescent Psychopharmacology, 15(1), 44–56. PubMedCrossRef Radigan, M., Lannon, P., et al. (2005). Medication patterns for attention deficit hyperactivity disorder and comorbid psychiatric conditions in a low-income population. Journal of Child and Adolescent Psychopharmacology, 15(1), 44–56. PubMedCrossRef
go back to reference Rice, C., Nicholas, J., et al. (2010). Changes in autism spectrum disorder prevalence in 4 areas of the United States. Disability and Health Journal, 3(3), 186–201. PubMedCrossRef Rice, C., Nicholas, J., et al. (2010). Changes in autism spectrum disorder prevalence in 4 areas of the United States. Disability and Health Journal, 3(3), 186–201. PubMedCrossRef
go back to reference Richardson, L. P., DiGiuseppe, D., et al. (2004). Quality of care for Medicaid-covered youth treated with antidepressant therapy. Archives of General Psychiatry, 61(5), 475–480. PubMedCrossRef Richardson, L. P., DiGiuseppe, D., et al. (2004). Quality of care for Medicaid-covered youth treated with antidepressant therapy. Archives of General Psychiatry, 61(5), 475–480. PubMedCrossRef
go back to reference Safer, D. J., Zito, J. M., et al. (2004). Comparative prevalence of psychotropic medications among youths enrolled in the SCHIP and privately insured youths. Psychiatric Services, 55(9), 1049–1051. PubMedCrossRef Safer, D. J., Zito, J. M., et al. (2004). Comparative prevalence of psychotropic medications among youths enrolled in the SCHIP and privately insured youths. Psychiatric Services, 55(9), 1049–1051. PubMedCrossRef
go back to reference Schatzberg, A., Cole, J., et al. (2010). Manual of clinical psychopharmacology. Arlington, VA: American Psychiatric Publishing. Schatzberg, A., Cole, J., et al. (2010). Manual of clinical psychopharmacology. Arlington, VA: American Psychiatric Publishing.
go back to reference Shattuck, P. T., Durkin, M., et al. (2009). Timing of identification among children with an autism spectrum disorder: Findings from a population-based surveillance study. Journal of the American Academy of Child and Adolescent Psychiatry, 48(5), 474–483. PubMedPubMedCentralCrossRef Shattuck, P. T., Durkin, M., et al. (2009). Timing of identification among children with an autism spectrum disorder: Findings from a population-based surveillance study. Journal of the American Academy of Child and Adolescent Psychiatry, 48(5), 474–483. PubMedPubMedCentralCrossRef
go back to reference Simonoff, E., Pickles, A., et al. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 921–929. PubMedCrossRef Simonoff, E., Pickles, A., et al. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 921–929. PubMedCrossRef
go back to reference Sleath, B., Domino, M., et al. (2010). Antidepressant and antipsychotic use and adherence among Medicaid-youths: Differences by race. Community Mental Health Journal, 46(3), 265–272. PubMedCrossRef Sleath, B., Domino, M., et al. (2010). Antidepressant and antipsychotic use and adherence among Medicaid-youths: Differences by race. Community Mental Health Journal, 46(3), 265–272. PubMedCrossRef
go back to reference Stone, V., Hogan, J., et al. (2001). Antiretroviral regimen complexity, self-reported adherence, and HIV patients’ understanding of their regimens: Survey of women in the HER study. JAIDS, 28(2), 124–131. PubMed Stone, V., Hogan, J., et al. (2001). Antiretroviral regimen complexity, self-reported adherence, and HIV patients’ understanding of their regimens: Survey of women in the HER study. JAIDS, 28(2), 124–131. PubMed
go back to reference Taylor, J., Dove, D., et al. (2012). Interventions for adolescents and young adults with autism spectrum disorders. A. f. H. R. a. Qualtiy. (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I.) AHRQ Publication No. 12-EHC063-EF. Rockville, MD: Agency for Healthcare Research and Quality. August 2012. http://​www.​effectivehealthc​are.​ahrq.​gov/​reports/​final.​cfm. Accessed September 03, 2013. Taylor, J., Dove, D., et al. (2012). Interventions for adolescents and young adults with autism spectrum disorders. A. f. H. R. a. Qualtiy. (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2007-10065-I.) AHRQ Publication No. 12-EHC063-EF. Rockville, MD: Agency for Healthcare Research and Quality. August 2012. http://​www.​effectivehealthc​are.​ahrq.​gov/​reports/​final.​cfm. Accessed September 03, 2013.
go back to reference Thompson, C., et al. (2000). Compliance with antidepressant medication in the treatment of major depressive disorder in primary care: A randomized comparison of fluoxetine and a tricyclic antidepressant. American Journal of Psychiatry, 157, 338–343. PubMedCrossRef Thompson, C., et al. (2000). Compliance with antidepressant medication in the treatment of major depressive disorder in primary care: A randomized comparison of fluoxetine and a tricyclic antidepressant. American Journal of Psychiatry, 157, 338–343. PubMedCrossRef
go back to reference Van Narden Braun, K., et al. (2008). Relationships between multiple births and autism spectrum disorders, cerebral palsy, and intellectual disabilities: Autism and developmental disabilities monitoring (ADDM) network—2002 surveillance year. Autism Research, 1(5), 265–316. CrossRef Van Narden Braun, K., et al. (2008). Relationships between multiple births and autism spectrum disorders, cerebral palsy, and intellectual disabilities: Autism and developmental disabilities monitoring (ADDM) network—2002 surveillance year. Autism Research, 1(5), 265–316. CrossRef
go back to reference Visser, S. N., Lesesne, C. A., et al. (2007). National estimates and factors associated with medication treatment for childhood attention-deficit/hyperactivity disorder. Pediatrics, 119(Supplement 1), S99–S106. PubMedCrossRef Visser, S. N., Lesesne, C. A., et al. (2007). National estimates and factors associated with medication treatment for childhood attention-deficit/hyperactivity disorder. Pediatrics, 119(Supplement 1), S99–S106. PubMedCrossRef
go back to reference Volkmar, F., & Wiesner, L. (2009). A practical guide to autism: What every parent, family member and teacher needs to know (pp. 458–459). Hoboken, NJ: Wiley. Volkmar, F., & Wiesner, L. (2009). A practical guide to autism: What every parent, family member and teacher needs to know (pp. 458–459). Hoboken, NJ: Wiley.
go back to reference Wiggins, L. D., Rice, C., & Baio, J. (2009). Developmental regression in children with an autism spectrum disorder identified by a population-based surveillance system. Autism, 13(4), 357–374. PubMedCrossRef Wiggins, L. D., Rice, C., & Baio, J. (2009). Developmental regression in children with an autism spectrum disorder identified by a population-based surveillance system. Autism, 13(4), 357–374. PubMedCrossRef
go back to reference Williams, A., Manias, E., et al. (2008). Interventions to improve medication adherence in people with multiple chronic conditions: A systematic review. Journal of Advanced Nursing, 63(2), 132–143. PubMedCrossRef Williams, A., Manias, E., et al. (2008). Interventions to improve medication adherence in people with multiple chronic conditions: A systematic review. Journal of Advanced Nursing, 63(2), 132–143. PubMedCrossRef
go back to reference Wink, L., & Erickson, C. (2010). Pharmacologic treatment of behavioral symptoms associated with autism and other pervasive developmental disorders. Current Treatment Options in Neurology, 12, 529–538. PubMedCrossRef Wink, L., & Erickson, C. (2010). Pharmacologic treatment of behavioral symptoms associated with autism and other pervasive developmental disorders. Current Treatment Options in Neurology, 12, 529–538. PubMedCrossRef
go back to reference Yeargin-Allsopp, M., Rice, C., Karapurkar, T., Doernberg, N., Boyle, C., & Murphy, C. (2003). Prevalence of autism in a US metropolitan area. JAMA, 289(1), 49–55. PubMedCrossRef Yeargin-Allsopp, M., Rice, C., Karapurkar, T., Doernberg, N., Boyle, C., & Murphy, C. (2003). Prevalence of autism in a US metropolitan area. JAMA, 289(1), 49–55. PubMedCrossRef
go back to reference Yeargin-Allsopp, M., Van Naarden Braun, K., Doernberg, N. S., Benedict, R. E., Kirby, R. S., & Durkin, M. S. (2008). Prevalence of cerebral palsy in 8-year-old children in three areas of the United States in 2002: A multisite collaboration. Pediatrics, 121(3), 547–554. PubMedCrossRef Yeargin-Allsopp, M., Van Naarden Braun, K., Doernberg, N. S., Benedict, R. E., Kirby, R. S., & Durkin, M. S. (2008). Prevalence of cerebral palsy in 8-year-old children in three areas of the United States in 2002: A multisite collaboration. Pediatrics, 121(3), 547–554. PubMedCrossRef
go back to reference Zito, J. M., Safer, D. J., Sai, D., Gardner, J. F., Thomas, D., Coombes, P., et al. (2008). Psychotropic medication patterns among youth in foster care. Pediatrics, 121(1), e157–e163. PubMedCrossRef Zito, J. M., Safer, D. J., Sai, D., Gardner, J. F., Thomas, D., Coombes, P., et al. (2008). Psychotropic medication patterns among youth in foster care. Pediatrics, 121(1), e157–e163. PubMedCrossRef
Metagegevens
Titel
Rates and Predictors of Adherence to Psychotropic Medications in Children with Autism Spectrum Disorders
Auteurs
Sarah L. Logan
Laura Carpenter
R. Scott Leslie
Kelly S. Hunt
Elizabeth Garrett-Mayer
Jane Charles
Joyce S. Nicholas
Publicatiedatum
01-11-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2156-0