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Gepubliceerd in: Quality of Life Research 5/2008

01-06-2008

Quality of life valuations of mammography screening

Auteurs: Amy E. Bonomi, Denise M. Boudreau, Paul A. Fishman, Evette Ludman, Amy Mohelnitzky, Elizabeth A. Cannon, Deb Seger

Gepubliceerd in: Quality of Life Research | Uitgave 5/2008

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Abstract

Objective To obtain quality-of-life (QOL) valuations associated with mammography screening and breast cancer treatment that are suitable for use in cost-effectiveness analyses.
Methods Subjects comprised 131 women (age range 50–79 years) randomly sampled from a breast cancer screening program. In an in-person or telephone interview, women rated the QOL impact of 14 clinical scenarios (ranging from mammography to end-of-life care for breast cancer) using a visual analogue scale anchored by death (0) and perfect health/quality of life (100).
Results Women rated the scenarios describing true negative results, false positive results, and routine screening mammography at 80 or above on a scale of 0–100, suggesting that they perceive these states as being close to perfect health. They rated adjuvant chemotherapy (39.7; range 10–90), palliation/end-of-life care (35.8; range 0–100), and recurrence at 1 year (33.0; range 0–95) the lowest, suggesting that these health states are perceived as compromised. Women rated receiving news of a breast cancer diagnosis (true positive) (45.7; range 5–100) and receiving delayed news of a breast cancer diagnosis (false negative) (48.5; range 5–100) as being comparable to undergoing mastectomy (48.3; range 10–100) and radiation therapy (46.2; range 5–100) for breast cancer.
Conclusions These data can be used to update cost analyses of mammography screening that wish to take into account the QOL impact of screening.
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Metagegevens
Titel
Quality of life valuations of mammography screening
Auteurs
Amy E. Bonomi
Denise M. Boudreau
Paul A. Fishman
Evette Ludman
Amy Mohelnitzky
Elizabeth A. Cannon
Deb Seger
Publicatiedatum
01-06-2008
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 5/2008
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-008-9353-2

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