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01-04-2010 | Uitgave 3/2010

Quality of life predicts one-year survival in patients with implantable cardioverter defibrillators

Tijdschrift:: Quality of Life Research > Uitgave 3/2010

Auteurs:: Chi-Wen Kao, Erika Friedmann, Sue A. Thomas

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Abstract

Purpose

This study examines the contributions of known predictors of survival and quality of life (QOL) to 1-year survival in ICD recipients.

Methods

This study used the data set from the antiarrhythmia versus implanted defibrillator (AVID) controlled clinical trial conducted by the National Institutes of Health, National Heart, Lung, and Blood Institute. The 507 patients randomly assigned to the ICD treatment were included in the analysis. Patients were mostly male (78.3%), with mean age of 64.85 ± 10.81 and mean left ventricular ejection fraction of 32.2 ± 13.45%. QOL was measured with the medical outcomes study 36-item short form health survey (SF-36) and quality of life index-cardiac version (QLI-CV). Data were analyzed with descriptive statistics and logistic regression.

Results

Fifty-four (10.6%) patients died in the first year after ICD implantation. Angiotensin-converting enzyme inhibitor (ACE) medication, age, and QLI-CV were significant independent predictors of 1-year survival. The odds of survival of a younger patient with ACE medication and good QOL were approximately three times (OR = 3.96) greater than for an older patient, without ACE medication and with poor QOL.

Conclusion

Quality of life is an important factor predicting 1-year survival in patients with ICDs. ACE medication and younger age also predict 1-year survival independent of QOL and each other.

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Titel: Quality of life predicts one-year survival in patients with implantable cardioverter defibrillators
Auteurs:: Chi-Wen Kao
Erika Friedmann
Sue A. Thomas
Publicatiedatum: 01-04-2010
DOI: https://doi.org/10.1007/s11136-010-9596-6
Uitgeverij: Springer Netherlands
Tijdschrift: Quality of Life Research An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation - An Official Journal of the International Society of Quality of Life Research
Uitgave 3/2010
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649

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Abstract

Purpose

Methods

Results

Conclusion

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