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15-02-2020

Quality of life may be a more valuable prognostic factor than depression in older hemodialysis patients

Auteurs: Saulo Barbosa Vasconcelos de Alencar, Luana do Amaral Dias, Victor do Amaral Dias, Fábia Maria de Lima, Ulisses Ramos Montarroyos, Kátia Cristina Lima de Petribú

Gepubliceerd in: Quality of Life Research | Uitgave 7/2020

Abstract

Purpose

Depression and impairment of quality of life (QoL) reduce the survival of individual on hemodialysis (HD). However, few studies evaluated the impact of these conditions on the survival of older patients undergoing HD.

Methods

A retrospective cohort study was performed including patients aged ≥ 60 years on HD in Recife, Brazil, assessed in 2013 and monitored until 2017. Depression was evaluated with the Mini-International Neuropsychiatric Interview and QoL with the Control, Autonomy, Self-realization, and Pleasure Questionnaire (CASP-16). Survival differences according to the depression and QoL status were measured by Kaplan–Meier analysis and Cox regression. Death Certificates were analyzed to assess the cause of death.

Results

A total of 171 patients were included (mean age 68.7 ± 6.9 years). The mean follow-up time was 3 years (maximum 4.5 years) and there were 98 deaths (57.3% of the sample). In a multivariate model that included depression and QoL, only QoL impairment was associated with a higher risk of death (HR 1.62, p = 0.035). Among CASP domains, only “Control” was associated with survival (HR 0.90, p = 0.014). Depression was unrelated to the cause of death, but there was a trend for death by endocrine diseases if QoL was impaired (p = 0.057).

Conclusion

QoL impairment is a key predictor of prognosis in older patients on HD and may be more important than depression. It is important that teams dealing with this population include in protocols an assessment of QoL, in order to offer a range of care according to the needs of these patients.

vorige artikel Predictive model of variables associated with health-related quality of life in patients with advanced chronic kidney disease receiving hemodialysis

volgende artikel Self-esteem in patients with inflammatory bowel disease

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Titel: Quality of life may be a more valuable prognostic factor than depression in older hemodialysis patients
Auteurs: Saulo Barbosa Vasconcelos de Alencar
Luana do Amaral Dias
Victor do Amaral Dias
Fábia Maria de Lima
Ulisses Ramos Montarroyos
Kátia Cristina Lima de Petribú
Publicatiedatum: 15-02-2020
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 7/2020
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-020-02445-1

Bohn Stafleu van Loghum

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Abstract

Purpose

Methods

Results

Conclusion

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