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19-06-2018

Quality of life in Sardinian patients with transfusion-dependent Thalassemia: a cross-sectional study

Auteurs: Francesca Floris, Federica Comitini, GiovanBattista Leoni, Paolo Moi, Maddalena Morittu, Valeria Orecchia, Maria Perra, Maria Paola Pilia, Antonietta Zappu, Maria Rosaria Casini, Raffaella Origa

Gepubliceerd in: Quality of Life Research | Uitgave 10/2018

Abstract

Purpose

The aim of this study has been to evaluate the physical, psychological, and social well-being in a large group of Sardinian adult patients with transfusion-dependent beta-Thalassemia when compared with a group of healthy subjects of the same age and geographical extraction.

Methods

Male or female patients ≥ 18 years of age with Thalassemia major on regular transfusion at Thalassemia Center in Cagliari (Italy) were requested to complete the World Health Organization Quality of life-BREF (WHOQOL-BREF) questionnaire. The WHOQOL-BREF was also made available online to age- and sex-matched non-thalassemic adult subjects living in Sardinia.

Results

Two hundred and seven subjects with Thalassemia were invited to participate in the study. The questionnaire was also completed by 211 age- and sex-matched non-thalassemic subjects living in Sardinia. Scores suggestive of a good quality of life were obtained in all the areas investigated. Thalassemia patients had scores at least as good as those of non-thalassemic subjects in all items and the percentage of those with a score ≥ 60 was higher among patients. The analysis of demographic actually highlights that the disease has a little effect on their personal and social lives. There was a positive association between subjective well-being and effective clinical conditions. Moreover, the association between health perception and adherence to treatment suggests that compliance with treatment contributes to the well-being of the patient, both physically and psychologically.

Conclusions

Adult subjects with Thalassemia who live in Western countries have a good quality of life in accordance with the advances in the management of the disease.

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Titel: Quality of life in Sardinian patients with transfusion-dependent Thalassemia: a cross-sectional study
Auteurs: Francesca Floris
Federica Comitini
GiovanBattista Leoni
Paolo Moi
Maddalena Morittu
Valeria Orecchia
Maria Perra
Maria Paola Pilia
Antonietta Zappu
Maria Rosaria Casini
Raffaella Origa
Publicatiedatum: 19-06-2018
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 10/2018
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-018-1911-7

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Abstract

Purpose

Methods

Results

Conclusions

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