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Quality of Life Research
Gepubliceerd in: Quality of Life Research 6/2022

18-10-2021

Quality of life in first episode psychosis: a cluster analytic approach

Auteurs: Z. Liao, K. Allott, J. F. I. Anderson, E. Killackey, S. M. Cotton

Gepubliceerd in: Quality of Life Research | Uitgave 6/2022

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Abstract

Purpose

Quality of life is increasingly recognised as an important outcome for young people with first episode psychosis (FEP). The first aim was to determine whether distinct homogenous subgroups of young people with FEP could be delineated based on profiles on quality of life domains (Physical Health, Psychological, Social relationships and Environmental). The second aim was to examine the discriminant validity of these subgroups with respect to demographic, functioning and clinical features of FEP.

Method

Quality of life, demographic characteristics, clinical characteristics, cognition and functioning were assessed in 145 people with FEP. Cluster analysis using Ward’s methods and Squared Euclidean Distance with a k-means verification were employed to identify subgroups with homogenous quality of life profiles. The clusters were externally validated using multinomial logistic regressions.

Results

Three distinct quality of life profiles were identified: one with good quality of life across all domains (30%), one with poor quality of life particularly in Psychological and Social relationships domains (28%), and one ‘intermediate’ group with comparatively low Psychological quality of life (42%). Depression, semantic verbal fluency, social inclusion and social/occupational functioning showed associations with group membership.

Conclusion

Our results suggest the potential of maintaining relatively good quality of life despite the experience of FEP. Future research on interventions to improve quality of life may consider the potential of addressing depression, social inclusion and social/occupational functioning.
vorige artikel Patient-reported outcomes associated with transition to secondary progressive multiple sclerosis
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Literatuur
1.
MacBeth, A., Gumley, A., Schwannauer, M., & Fisher, R. (2015). Self-reported quality of life in a Scottish first-episode psychosis cohort: Associations with symptomatology and premorbid adjustment. Early Intervention in Psychiatry, 9(1), 53–60.PubMedCrossRef
2.
The World Health Organization. (1996). WHOQOL-BREF: Introduction, Administration, Scoring and Generic Version of the Assessment.
3.
Addington, J., Young, J., & Addington, D. (2003). Social outcome in early psychosis. Psychological Medicine, 33(6), 1119–1124.PubMedCrossRef
4.
Renwick, L., Jackson, D., Foley, S., Owens, E., Ramperti, N., Behan, C., Anwar, M., Kinsella, A., Turner, N., Clarke, M., & O’Callaghan, E. (2012). Depression and quality of life in first-episode psychosis. Comprehensive Psychiatry, 53(5), 451–455.PubMedCrossRef
5.
Satghare, P., Abdin, E., Shahwan, S., Chua, B. Y., Poon, L. Y., Chong, S. A., & Subramaniam, M. (2019). Subjective quality of life and its associations among first episode psychosis patients in Singapore. International Journal of Environmental Research and Public Health, 17(1), 260.PubMedCentralCrossRef
6.
Cotton, S. M., Gleeson, J. F., Alvarez-Jimenez, M., & McGorry, P. D. (2010). Quality of life in patients who have remitted from their first episode of psychosis. Schizophrenia Research, 121(1–3), 259–265.PubMedCrossRef
7.
Watson, P., Zhang, J. P., Rizvi, A., Tamaiev, J., Birnbaum, M. L., & Kane, J. (2018). A meta-analysis of factors associated with quality of life in first episode psychosis. Schizophrenia Research, 202, 26–36.PubMedCrossRef
8.
Wegener, S., Redoblado-Hodge, M. A., Lucas, S., Fitzgerald, D., Harris, A., & Brennan, J. (2005). Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Australian and New Zealand Journal of Psychiatry, 39(6), 487–492.CrossRefPubMed
9.
Kenney, J., Anderson-Schmidt, H., Scanlon, C., Arndt, S., Scherz, E., McInerney, S., McFarland, J., Byrne, F., Ahmed, M., Donohoe, G., Hallahan, B., McDonald, C., & Cannon, D. M. (2015). Cognitive course in first-episode psychosis and clinical correlates: A 4 year longitudinal study using the MATRICS Consensus Cognitive Battery. Schizophrenia Research, 169(1–3), 101–108.PubMedCrossRef
10.
Jaracz, K., Górna, K., Kiejda, J., Grabowska-Fudala, B., Jaracz, J., Suwalska, A., & Rybakowski, J. K. (2015). Psychosocial functioning in relation to symptomatic remission: A longitudinal study of first episode schizophrenia. European Psychiatry, 30(8), 907–913.PubMedCrossRef
11.
Haidt, J. (2006). The happiness hypothesis: finding modern truth in ancient wisdom. Basic Books.
12.
Uren, J., Cotton, S. M., Killackey, E., Saling, M. M., & Allott, K. (2017). Cognitive clusters in first-episode psychosis: Overlap with healthy controls and relationship to concurrent and prospective symptoms and functioning. Neuropsychology, 31(7), 787–797.PubMedCrossRef
13.
Reser, M. P., Allott, K. A., Killackey, E., Farhall, J., & Cotton, S. M. (2015). Exploring cognitive heterogeneity in first-episode psychosis: What cluster analysis can reveal. Psychiatry Research, 229(3), 819–827.PubMedCrossRef
14.
Killackey, E., Allott, K., Jackson, H. J., Scutella, R., Tseng, Y. P., Borland, J., Proffitt, T. M., Hunt, S., Kay-Lambkin, F., Chinnery, G., Baksheev, G., Alvarez-Jimenez, M., McGorry, P. D., & Cotton, S. M. (2019). Individual placement and support for vocational recovery in first-episode psychosis: Randomised controlled trial. British Journal of Psychiatry, 214(2), 76–82.CrossRef
15.
Killackey, E., Allott, K., Cotton, S. M., Jackson, H., Scutella, R., Tseng, Y. P., Borland, J., Proffitt, T. M., Hunt, S., Kay-Lambkin, F., Chinnery, G., Baksheev, G., Alvarez-Jimenez, M., & McGorry, P. D. (2013). A randomized controlled trial of vocational intervention for young people with first-episode psychosis: Method. Early Intervention in Psychiatry, 7(3), 329–337.PubMedCrossRef
16.
American Psychiatric Association. (2011). Diagnostic and statistical manual of mental disorders (4th ed.). ABC-CLIO LLC.
17.
Mas-Expósito, L., Amador-Campos, J. A., Gómez-Benito, J., & Lalucat-Jo, L. (2011). The World Health Organization Quality of Life Scale Brief Version: A validation study in patients with schizophrenia. Quality of Life Research, 20(7), 1079–1089.PubMedCrossRef
18.
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (2001). Structured clinical interview for DSM-IV-TR Axis I Disorders—Patient Edition.
19.
Overall, J. E., & Gorham, D. R. (1962). The brief psychiatric rating scale. Psychological Reports, 10(3), 799–812.CrossRef
20.
Andreasen, N. C., King, S., & Waller, N. G. (1984). Scale for the Assessment of Negative Symptoms.
21.
Radloff, L. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1(3), 385–401.CrossRef
22.
Maat, A., Fett, A. K., & Derks, E. (2012). Social cognition and quality of life in schizophrenia. Schizophrenia Research, 137(1–3), 212–218.PubMedCrossRef
23.
Tolman, A. W., & Kurtz, M. M. (2012). Neurocognitive predictors of objective and subjective quality of life in individuals with schizophrenia: A meta-analytic investigation. Schizophrenia Bulletin, 38(2), 304–315.PubMedCrossRef
24.
Ardila, A., Pineda, D., & Rosselli, M. (2000). Correlation between intelligence test scores and executive function measures. Archives of Clinical Neuropsychology, 15(1), 31–36.PubMedCrossRef
25.
Strauss, E., Sherman, E. M. S., & Spreen, O. (2006). A compendium of neuropsychological tests: Administration, norms, and commentary (3rd ed.): Oxford University Press.
26.
Langdon, R., & Coltheart, M. (1999). Mentalising, schizotypy, and schizophrenia. Cognition, 71(1), 43–71.PubMedCrossRef
27.
The Psychological Corporation. (1997). WAIS-III and WMS-III Technical Manual. San Antonio.
28.
Goldman, H. H., Skodol, A. E., & Lave, T. R. (1992). Revising axis V for DSM-IV: A review of measures of social functioning. American Journal of Psychiatry, 149(9), 1148–1156.CrossRefPubMed
29.
Secker, J., Hacking, S., Kent, L., Shenton, J., & Spandler, H. (2009). Development of a measure of social inclusion for arts and mental health project participants. Journal of Mental Health, 18(1), 65–72.CrossRef
30.
IBM Corp. (2017). IBM SPSS Statistics for Windows, Version 25.0. IBM Corp.
31.
Ward, J. H., Jr. (1963). Hierarchical grouping to optimize an objective function. Journal of the American Statistical Association, 58, 236.CrossRef
32.
Tabachnick, B. G., & Fidell, L. S. (2013). Using multivariate statistics (6th ed.): Pearson.
33.
Hawthorne, G., Herrman, H., & Murphy, B. (2006). Interpreting the WHOQOL-Brèf: Preliminary population norms and effect sizes. Social Indicators Research, 77(1), 37–59.CrossRef
34.
Allott, K. A., Cotton, S. M., Chinnery, G. L., Baksheev, G. N., Massey, J., Sun, P., Collins, Z., Barlow, E., Broussard, C., Wahid, T., Proffitt, T. M., Jackson, H. J., & Killackey, E. (2013). The relative contribution of neurocognition and social cognition to 6-month vocational outcomes following Individual Placement and Support in first-episode psychosis. Schizophrenia Research, 150(1), 136–143.PubMedCrossRef
35.
Fleiss, J. L., Levin, B. A., & Paik, M. C. (2003). Statistical methods for rates and proportions (3rd ed.). Wiley.
36.
Song, Y. Y., Kim, K. R., Park, J. Y., Lee, S. Y., Kang, J. I., Lee, E., An, S. K., & Kwon, J. S. (2011). Associated factors of quality of life in first-episode schizophrenia patients. Psychiatry Investigation, 8(3), 201–206.PubMedPubMedCentralCrossRef
37.
Law, C. W., Chen, E. Y., Cheung, E. F., Chan, R. C., Wong, J. G., Lam, C. L., Leung, K. F., & Lo, M. S. (2005). Impact of untreated psychosis on quality of life in patients with first-episode schizophrenia. Quality of Life Research, 14(8), 1803–1811.PubMedCrossRef
38.
Agid, O., McDonald, K., Siu, C., Tsoutsoulas, C., Wass, C., Zipursky, R. B., Foussias, G., & Remington, G. (2012). Happiness in first-episode schizophrenia. Schizophrenia Research, 141(1), 98–103.PubMedCrossRef
39.
Conversano, C., Rotondo, A., Lensi, E., Della Vista, O., Arpone, F., & Reda, M. A. (2010). Optimism and its impact on mental and physical well-being. Clinical Practice and Epidemiology in Mental Health, 6, 25–29.PubMedPubMedCentralCrossRef
40.
Boyette, L. L., van Dam, D., Meijer, C., Velthorst, E., Cahn, W., de Haan, L., Kahn, R., de Haan, L., van Os, J., Wiersma, D., Bruggeman, R., Cahn, W., Meijer, C., & Myin-Germeys, I. (2014). Personality compensates for impaired quality of life and social functioning in patients with psychotic disorders who experienced traumatic events. Schizophrenia Bulletin, 40(6), 1356–1365.PubMedPubMedCentralCrossRef
41.
42.
43.
Sim, K., Mahendran, R., Siris, S. G., Heckers, S., & Chong, S. A. (2004). Subjective quality of life in first episode schizophrenia spectrum disorders with comorbid depression. Psychiatry Research, 129(2), 141–147.PubMedCrossRef
44.
Kwong, V. W., Chang, W. C., Chan, G. H., Jim, O. T., Lau, E. S., Hui, C. L., Chan, S. K., Lee, E. H., & Chen, E. Y. (2017). Clinical and treatment-related determinants of subjective quality of life in patients with first-episode psychosis. Psychiatry Research, 249, 39–45.PubMedCrossRef
45.
Herniman, S. E., Allott, K., Phillips, L. J., Wood, S. J., Uren, J., Mallawaarachchi, S. R., & Cotton, S. M. (2019). Depressive psychopathology in first-episode schizophrenia spectrum disorders: A systematic review, meta-analysis and meta-regression. Psychological Medicine, 49(15), 2463–2474.PubMedCrossRef
46.
Torrent, C., Reinares, M., Martinez-Arán, A., Cabrera, B., Amoretti, S., Corripio, I., Contreras, F., Sarró, S., González-Pinto, A., Lobo, A., Cuesta, M. J., Sánchez-Torres, A., Bergé, D., Castro-Fornieles, J., Moreno, C., Bernardo, M., & Vieta, E. (2018). Affective versus non-affective first episode psychoses: A longitudinal study. Journal of Affective Disorders, 238, 297–304.PubMedCrossRef
47.
Cotton, S. M., Lambert, M., Schimmelmann, B. G., Mackinnon, A., Gleeson, J. F. M., Berk, M., Hides, L., Chanen, A., McGorry, P. D., & Conus, P. (2012). Depressive symptoms in first episode schizophrenia spectrum disorder. Schizophrenia Research, 134(1), 20–26.PubMedCrossRef
48.
Malla, A. K., Norman, R. M., McLean, T. S., MacDonald, C., McIntosh, E., Dean-Lashley, F., Lynch, J., Scholten, D., & Ahmed, R. (2004). Determinants of quality of life in first-episode psychosis. Acta Psychiatrica Scandinavica, 109(1), 46–54.PubMedCrossRef
49.
Gardner, A., Filia, K., Killackey, E., & Cotton, S. (2019). The social inclusion of young people with serious mental illness: A narrative review of the literature and suggested future directions. Australian and New Zealand Journal of Psychiatry, 53(1), 15–26.CrossRefPubMed
50.
Chee, K. Y. (2010). Determinants of subjective quality of life in first-episode schizophrenia: Perspective from Malaysia. Early Intervention in Psychiatry, 4(2), 111–118.PubMedCrossRef
51.
Boyer, L., Millier, A., Perthame, E., Aballea, S., Auquier, P., & Toumi, M. (2013). Quality of life is predictive of relapse in schizophrenia. BMC Psychiatry, 13, 15.PubMedPubMedCentralCrossRef
52.
Bow-Thomas, C. C., Velligan, D. I., Miller, A. L., & Olsen, J. (1999). Predicting quality of life from symptomatology in schizophrenia at exacerbation and stabilization. Psychiatry Research, 86(2), 131–142.PubMedCrossRef
Metagegevens
Titel
Quality of life in first episode psychosis: a cluster analytic approach
Auteurs
Z. Liao
K. Allott
J. F. I. Anderson
E. Killackey
S. M. Cotton
Publicatiedatum
18-10-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 6/2022
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-03014-w

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