Swipe om te navigeren naar een ander artikel
We sought to compare the quality of life (QOL), characteristics, and survival of patients with non-Hodgkin lymphoma (NHL) with and without human immunodeficiency virus (HIV) infection.
Using the population-based cancer registry for Orange and San Diego Counties, We recruited 50 patients with HIV and systemic NHL (cases) and 50 age, sex and race-matched NHL patients without HIV (controls) diagnosed with NHL during 2002–2006. Patients completed a medical history survey and QOL instrument, the Functional Assessment of Human Immunodeficiency Virus Infection (FAHI) for cases and Functional Assessment of Cancer Therapy-General (FACT G) for controls.
HIV-infected patients had worse overall QOL and survival than uninfected patients. QOL differences were more marked in the areas of functional, physical and social well-being than in the area of emotional well-being. HIV-infected patients had lower income and were less likely to have private insurance and more likely to have diffuse large B cell histology than uninfected patients.
HIV-infected NHL patients had worse QOL and survival than uninfected patients, due to a combination of co-morbidity, aggressive histology and lack of social support. However, their emotional well-being was comparable to that of uninfected NHL patients and better than historical norms for the HIV-infected.
Coté, T. R., Biggar, R. J., Rosenberg, P. S., Devesa, S. S., Percy, C., Yellin, F. J., et al. (1997). Non-Hodgkin’s lymphoma among people with AIDS: Incidence, presentation and public health burden. AIDS/cancer study group. International Journal of Cancer, 73, 645–650. CrossRef
Remick, S. C., Sedransk, N., Haase, R. F., Blanchard, C. G., Ramnes, C. R., Nazeer, T., et al. (2001). Oral combination chemotherapy in conjunction with filgrastim (G-CSF) in the treatment of AIDS-related non-Hodgkin’s lymphoma: Evaluation of the role of G-CSF; quality-of-life analysis and long-term follow-up. American Journal of Hematology, 66, 178–188. CrossRefPubMed
Martí-Carvajal, A. J., Cardona, A. F., Lawrence, A. (2009). Interventions for previously untreated patients with AIDS-associated Non-Hodgkin′s Lymphoma. Cochrane Database of Systematic Reviews, 3, CD005419.
Centers for Disease Control and Prevention (2009). HIV/AIDS surveillance report, 2007. Atlanta: US Department of Health and Human Services, Centers for Disease Control and Prevention, 19: 12.
Goldman, D. P., Leibowitz, A. A., Joyce, G. F., Fleishman, J. A., Bozzette, S. A., Duan, N., et al. (2003). Insurance status of HIV-infected adults in the post-HAART era: evidence from the United States. Applied Health Economics and Health Policy, 2, 85–90. PubMed
Cella, D. F., Tulsky, D. S., Gray, G., Sarafian, B., Linn, E., Bonomi, A., et al. (1993). The functional assessment of cancer therapy scale: Development and validation of the general measure. Journal of Clinical Oncology, 11, 570–579. PubMed
Fritz, A., Percy, C., Jack, A., Kanagaratnam, S., Sobin, L., Parkin, D. M., et al. (2000). International classification of diseases for oncology (3rd ed., pp. 98–100). Geneva: World Health Organization.
Brucker, P. S., Yost, K., Cashy, J., Webster, K., & Cella, D. (2005). General population and cancer patient norms for the Functional assessment of cancer therapy-general (FACT-G). Evaluation & the Health Professions, 28, 192–211. CrossRef
Holly, E. A., & Lele, C. (1997). Non-Hodgkin’s lymphoma in HIV-positive and HIV-negative homosexual men in the San Francisco Bay Area: Allergies, prior medication use, and sexual practices. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 15, 211–222. PubMed
Centers for Disease Control and Prevention (2005). Reported CD4+ T-lymphocyte results for adults and adolescents with HIV/AIDS—33 states, 2005. HIV/AIDS Surveillance Supplemental Report, 11, 12.
- Quality of life, characteristics and survival of patients with HIV and lymphoma
Thomas H. Taylor
- Springer Netherlands