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Filiz M. Sertpoyraz, İzmir Tepecik Training & Research Hospital; Barış Nacır Ankara Training & Research Hospital; Ömer Faruk Şendur, Adnan Menderes University School of Medicine; Melek Sezgin Mersin University School of Medicine, Ferda Özkan, Ankara Physical Medicine and Rehabilitation Training & Research Hospital, Figen Ayhan Ankara Training & Research Hospital; Ali Sallı Selçuk University School of Medicine; O. Hakan Gündüz, Marmara University School of Medicine; Sami Hizmetli, Cumhuriyet University School of Medicine; Funda Atamaz, Ege University School of Medicine.
To evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine.
Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of SpondyloArthritis International Society core outcome domains including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), fatigue (BASDAI-question 1), pain (last week/spine/due to AS), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and two QoL questionnaires (the disease-specific ASQoL and generic the Short Form-36 [SF-36]).
The mean ASQoL score was 7.1 ± 5.7. SF-36 subscales of general health, physical role and bodily pain had the poorest scores. ASQoL was strongly correlated with disease duration, BASDAI, fatigue, BASFI, BASMI, BASRI, MASES, pain and SF-36 subscales (P < 0.001). SF-36 subscales were also strongly correlated with BASDAI and BASFI. Advanced educational status and regular exercise habits positively affected QoL, while smoking negatively affected QoL.
In patients with AS, the most significant variables associated with QoL were BASDAI, BASFI, fatigue and pain. ASQoL was noted to be a short, rapid and simple patient-reported outcome (PRO) instrument and strongly correlated with SF-36 subscales.
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Bostan, E. E., Borman, P., Bodur, H., et al. (2003). Functional disability and quality of life in patients with ankylosing spondylitis. Rheumatology International, 23, 121–126. PubMed
van der Heijde, D. M., Revicki, D. A., Gooch, K. L., et al. (2009). Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients. Arthritis Research & Therapy, 11, R124. doi: 10.1186/ar2790.
Sieper, J., Rudwaleit, M., Baraliakos, X., et al. (2009). The assessment of spondyloarhritis international society (ASAS) handbook: A guide to assess spondyloarthritis. Annals of the Rheumatic Diseases, 68, 114–144. doi: 10.1136/ard.2008.104018.
Braun, J., Golder, W., Bollow, M., Sieper, J., & van der Heijde, D. (2002). Imaging and scoring in ankylosing spondylitis. Clinical and Experimental Rheumatology, 20(Suppl. 28), S178–S184. PubMed
Duruoz, T., Doward, L., Cerrahoglu, L., et al. Translation and validation of the Turkish version of the ankylosing spondylitis quality of life (ASQoL) Questionnaire. EULAR 2008 Abstract Book, Paris, France, 11–14 June 2008.
Demirsoy, A. C. (1999). The MOS SF-36 health survey: A validation study with a Turkish sample. Thesis, Bogazici University, İstanbul.
Salaffi, F., Carotti, M., Gasparini, S., et al. (2009). The health-related quality of life in rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis: A comparison with a selected sample of healthy people. Health and Quality of Life Outcomes, 7, 25. doi: 10.1186/1477-7525-7-25. PubMedCrossRef
Ward, M. M. (2002). Predictor of the progression of functional disability in patients with ankylosing spondylitis. Journal of Rheumatology, 29, 1420–1425. PubMed
- Quality of life and related variables in patients with ankylosing spondylitis
Derya Soy Buğdaycı
- Springer Netherlands