Skip to main content
Mijn bibliotheek
Shop
Nieuws Boeken Tijdschriften Toetsvragen Web-tv Video Audio
Tips voor Mijn BSL
Inloggen
Top
Quality of Life Research

19-11-2024 | Review

Quality of life among obstructive sleep apnoea patients: a systematic review and meta-analysis of EQ-5D studies

Gepubliceerd in: Quality of Life Research

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

Background

Obstructive Sleep Apnoea (OSA) is a chronic condition which is associated with extreme daytime sleepiness, cognitive impairment, and other comorbidities and, hence, decreased quality of life (QoL). EQ-5D is one of the most widely used preference-based measures of QoL in patients with different diseases worldwide. This study aims to review the EQ-5D utility value of OSA across primary studies and perform a meta-analysis to derive pooled utility scores for OSA.

Methods

A systematic review and meta-analysis of the EQ-5D scores of OSA patients adhering to PRISMA guidelines was conducted. Studies reporting EQ-5D utility scores among adult OSA patients were systematically searched across PubMed-Medline, Scopus, and Embase. Selected studies were systematically reviewed and we have assessed the studies for their quality. Meta‐analysis was performed using a random‐effect model with subgroup analysis to explore heterogeneity.

Results

The search yielded 9,121 articles, of which twenty-eight studies were included in the synthesis. The pooled mean EQ-5D utility score was 0.73 (0.69 to 0.78) with high heterogeneity (I2 = 99.6%). The pooled EQ-5D VAS score was 67.14 (63.97 to 70.32) with high heterogeneity (I2 = 87.04%). Subgroup analyses indicated significant variability in utility scores across different countries, age groups, and disease severities. The variation of utility values for OSA was influenced by the characteristics of patients, the living environment, and the EQ-5D value set.

Conclusion

The synthesis revealed that the QoL is significantly lower in OSA, and the aggregated quantitative estimates of EQ-5D utility scores are essential inputs for economic evaluations.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
1.
Sankri-Tarbichi, A. G. (2012). Obstructive sleep apnea-hypopnea syndrome: Etiology and diagnosis. Avicenna Journal of Medicine, 02(01), 3–8.CrossRef
2.
Benjafield, A. V., Ayas, N. T., Eastwood, P. R., Heinzer, R., Ip, M. S. M., Morrell, M. J., et al. (2019). Estimation of the global prevalence and burden of obstructive sleep apnoea: A literature-based analysis. The Lancet Respiratory Medicine, 7(8), 687–698.PubMedPubMedCentralCrossRef
3.
Lacasse, Y., Godbout, C., & Sériès, F. (2002). Health-related quality of life in obstructive sleep apnoea. European Respiratory Journal, 19(3), 499–503.PubMedCrossRef
4.
World Health Organization (WHO). WHOQOL User Manual. 1998.
5.
Programme on Mental Health. WHOQOL User Manual. 1998.
6.
Baldwin, C. M., Griffith, K. A., Nieto, F. J., O’Connor, G. T., Walsleben, J. A., & Redline, S. (2001). The association of sleep-disordered breathing and sleep symptoms with quality of life in the sleep heart health study. Sleep, 24(1), 96–105.PubMedCrossRef
7.
Moyer, C. A., Sonnad, S. S., Garetz, S. L., Helman, J. I., & Chervin, R. D. (2001). Quality of life in obstructive sleep apnea: A systematic review of the literature. Sleep Medicine, 2(6), 477–491.PubMedCrossRef
8.
9.
Pauletto, P., Réus, J. C., Bolan, M., Massignan, C., Flores-Mir, C., Maia, I., et al. (2021). Association between obstructive sleep apnea and health-related quality of life in untreated adults: A systematic review. Sleep Breath., 25(4), 1773–1789.PubMedCrossRef
10.
Pattnaik K P.' Some Nonwelfaristic Issues in Welfare Economics. In: Dutta B, editor. Welfare economics. New Delhi: Oxford University Press; 1994. p. 476–81.
11.
Dutt N, Mohapatra PR, Chauhan NK, Kuwal A, Chaudhry K. Health-Related Quality of Life in Obstructive Sleep Apnea Syndrome. Ann Natl Acad Med Sci. 2013;49(3&4).
12.
13.
Zhou T, Guan H, Wang L, Zhang Y, Rui M, Ma A. Health-Related Quality of Life in Patients With Different Diseases Measured With the EQ-5D-5L: A Systematic Review. Front Public Heal. 2021;9(June).
14.
15.
Devlin, N. J., & Brooks, R. (2017). EQ-5D and the EuroQol group: Past, present and future. Applied Health Economics and Health Policy, 15(2), 127–137.PubMedPubMedCentralCrossRef
16.
Herdman, M., Gudex, C., Lloyd, A., Janssen, M., Kind, P., Parkin, D., et al. (2011). Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of Life Research, 20(10), 1727–1736.PubMedPubMedCentralCrossRef
17.
Remenschneider AK, BS LD, T.Gray S, Holbrook EH, Gliklich RE, Metson R. The EQ-5D: A New Tool for Studying Clinical Outcomes in Chronic Rhinosunsitis. 2014. p. 7–15.
18.
19.
Xu, R. H., Cheung, A. W. L., & Wong, E. L. Y. (2017). The relationship between shared decision-making and health-related quality of life among patients in Hong Kong SAR. International Journal for Quality in Health Care, 29(4), 534–540.PubMedCrossRef
20.
Xu RH, Sun R, Tian L, Cheung AW ling, Wong EL. Health-related quality of life in primary care patients: a comparison between EQ-5D-5L utility score and EQ-visual analogue scale. Health Qual Life Outcomes [Internet]. 2024;22(1):1–11. Available from: https://​doi.​org/​10.​1186/​s12955-023-02215-w
21.
22.
Wisløff, T., Hagen, G., Hamidi, V., Movik, E., Klemp, M., & Olsen, J. A. (2014). Estimating QALY gains in applied studies: A review of cost-utility analyses published in 2010. PharmacoEconomics, 32(4), 367–375.PubMedPubMedCentralCrossRef
23.
24.
Janssen, M. F., Pickard, A. S., Golicki, D., Gudex, C., Niewada, M., Scalone, L., et al. (2013). Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups: A multi-country study. Quality of Life Research, 22(7), 1717–1727.PubMedCrossRef
25.
26.
Van Hout, B., Janssen, M. F., Feng, Y. S., Kohlmann, T., Busschbach, J., Golicki, D., et al. (2012). Interim scoring for the EQ-5D-5L: Mapping the EQ-5D-5L to EQ-5D-3L value sets. Value Heal., 15(5), 708–715.CrossRef
27.
28.
Whitehead, S. J., & Ali, S. (2010). Health outcomes in economic evaluation: The QALY and utilities. British Medical Bulletin, 96(1), 5–21.PubMedCrossRef
29.
Drummond M, Sculpher M, Claxton K, Stoddart GL, Torrance G. Methods for the Economic Evaluation of Health Care Programmes. 4th ed. Oxford University Press; 2015. 1–429 p.
30.
31.
Borenstein M, Hedges H, Higgins J, Rothstein H. INTRODUCTION TO Introduction to cogeneration. Vol. 79. Wiley; 2019. 1–415 p.
32.
Deeks J J, Higgins JP, Altman; DG, Group on behalf of the CSM. Analyzing data and undertaking meta‐analyses. Cochrane handbook for systematic reviews of interventions. The Cochrane Collaboration. 2019. 1–100 p.
33.
C S. An analysis of RSBY enrolment patterns: 84 Preliminary evidence and lessons from the early experience. In: Palacios R, Das J, Sun C, editors. India's health insurance scheme for the poor evidence from the early experience of RSBY. New Delhi: Centre for Policy Research; 2011. p. 84–116.
34.
Higgins, J. P. T., Altman, D. G., Gøtzsche, P. C., Jüni, P., Moher, D., Oxman, A. D., et al. (2011). The Cochrane Collaboration’s tool for assessing risk of bias in randomized trials. BMJ, 343(7829), 1–9.
35.
Well, S., O’Connell, D., Peterson, J., Welch, V., Losos, M., Tugwell, P., et al. (2014). Newcastle-Ottawa quality assessment scale. Ottawa Hosp Res Institute, 3, 2–4.
36.
Deeks JJ, Higgins JPT AD (editors). 9.5.2 Identifying and measuring heterogeneity [Internet]. Chapter 9: Section, Analyzing data and undertaking meta-analyses. 9.5.2. In: Higgins JPT, Green S (editors). Cochrane Interventions, Handbook for Systematic Reviews of Cochrane, Version 5.0.2 (updated September 2009). The Collaboration, 2009. 2009. 100 p. Available from: www.​cochranehandbook​.​org
37.
DerSimonian, R., & Laird, N. (1986). Meta-analysis in clinical trials. Controlled Clinical Trials, 7(3), 177–188.PubMedCrossRef
38.
Baptista, P., Di Frisco, I. M., Urrestarazu, E., Alcalde, J., Alegre, M., Sanchez, I., et al. (2022). Quality of life impact of hypoglossal nerve stimulation with inspire® device in patients with obstructive sleep apnea intolerant to continuous positive airway pressure therapy. Life., 12(11), 1737.PubMedPubMedCentralCrossRef
39.
Cambron-Mellott MJ, Mettam S, Li VW, Rowland JC, Castro JPC. Examining the impact of excessive daytime sleepiness on utility scores in patients with obstructive sleep apnoea and/or narcolepsy in five European countries. BMC Neurol [Internet]. 2022;22(1):1–9. Available from: https://​doi.​org/​10.​1186/​s12883-022-02827-7
40.
Kataoka H, Miyatake N, Ichikawa H, Arakawa Y, Mori Y. Sub-analysis of the prevalence of locomotive syndrome and its relationship with health-related quality of life in patients with obstructive sleep apnea syndrome as classified by age and sex. Sleep Biol Rhythms [Internet]. 2019;17(1):149–53. Available from: https://​doi.​org/​10.​1007/​s41105-018-0194-2
41.
Krishnan, S., Chai-Coetzer, C. L., Grivell, N., Lovato, N., Mukherjee, S., Vakulin, A., et al. (2022). Comorbidities and quality of life in Australian men and women with diagnosed and undiagnosed high-risk obstructive sleep apnea. Journal of Clinical Sleep Medicine, 18(7), 1757–1767.PubMedPubMedCentralCrossRef
42.
Kuik, K., Tan, M. L., Ho, J. P. T. F., Lindeboom, J. A. H., & de Lange, J. (2023). Subjective efficiency evaluation after maxillomandibular advancement surgery in obstructive sleep apnea patients. Journal of Clinical Medicine, 12(12), 4–11.CrossRef
43.
Lugo, V. M., Garmendia, O., Suarez-Girón, M., Torres, M., Vázquez-Polo, F. J., Negrín, M. A., et al. (2019). Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial. PLoS One., 14(10), 1–15.
44.
Masa, J. F., Jiménez, A., Durán, J., Carmona, C., Monasterio, C., Mayos, M., et al. (2011). Visual analogical well-being scale for sleep apnea patients: Validity and responsiveness. Sleep Breath, 15(3), 549–559.PubMedCrossRef
45.
McMillan, A., Bratton, D. J., Faria, R., Laskawiec-Szkonter, M., Griffin, S., Davies, R. J., et al. (2014). Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): A 12-month, multicentre, randomized trial. The Lancet Respiratory Medicine, 2(10), 804–812.PubMedCrossRef
46.
Quinnell, T. G., Bennett, M., Jordan, J., Clutterbuck-James, A. L., Davies, M. G., Smith, I. E., et al. (2014). A crossover randomized controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO). Thorax, 69(10), 938–945.PubMedCrossRef
47.
Sánchez-De-La-Torre, M., Nadal, N., Cortijo, A., Masa, J. F., Duran-Cantolla, J., Valls, J., et al. (2015). Role of primary care in the follow-up of patients with obstructive sleep apnoea undergoing CPAP treatment: A randomized controlled trial. Thorax, 70(4), 346–352.PubMedCrossRef
48.
Schmidlin, M., Fritsch, K., Matthews, F., Thurnheer, R., Senn, O., & Bloch, K. E. (2010). Utility indices in patients with the obstructive sleep apnea syndrome. Respiration, 79(3), 200–208.PubMedCrossRef
49.
Weaver, T. E., Drake, C. L., Benes, H., Stern, T., Maynard, J., Thein, S. G., et al. (2020). Effects of solriamfetol on quality-of-life measures from a 12-week phase 3 randomized controlled trial. Annals of the American Thoracic Society, 17(8), 998–1007.PubMedPubMedCentralCrossRef
50.
51.
Wimms, A. J., Kelly, J. L., Turnbull, C. D., McMillan, A., Craig, S. E., O’Reilly, J. F., et al. (2020). Continuous positive airway pressure versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): A multicentre, randomized controlled trial. The Lancet Respiratory Medicine, 8(4), 349–358.PubMedCrossRef
52.
Zamarrón, E., Jaureguizar, A., García-Sánchez, A., Díaz-Cambriles, T., Alonso-Fernández, A., Lores, V., et al. (2023). continuous positive airway pressure effect on albuminuria progression in patients with obstructive sleep apnea and diabetic kidney disease: A randomised clinical trial. American Journal of Respiratory and Critical Care Medicine, 207(6), 757–767.PubMedCrossRef
53.
Olszewska, E., Vasilenok, N., Polecka, A., Stróżyński, A., Olszewska, N., Rogowski, M., et al. (2022). Long-term outcomes of pharyngoplasty for obstructive sleep apnea syndrome. Otolaryngologia Polska, 76(3), 18–25.PubMedCrossRef
54.
Pépin, J. L., Georgiev, O., Tiholov, R., Attali, V., Verbraecken, J., Buyse, B., et al. (2021). Pitolisant for residual excessive daytime sleepiness in OSA patients adhering to CPAP: A randomised trial. Chest, 159(4), 1598–1609.PubMedCrossRef
55.
Zota, I. M., Constantin, M. M. L., Stătescu, C., Sascău, R. A., Roca, M., Gavril, R. S., et al. (2020). Clinical and biological impact of CPAP therapy in patients with obstructive sleep apnea and cardio-metabolic comorbidities. Acta Medica Mediterr., 36(3), 1975–1979.
56.
Corrigan, J., Tsai, W. H., Ip-Buting, A., Ng, C., Ogah, I., Peller, P., et al. (2022). Treatment outcomes among rural and urban patients with obstructive sleep apnea: A prospective cohort study. Journal of Clinical Sleep Medicine, 18(4), 1013–1020.PubMedPubMedCentralCrossRef
57.
Dauvilliers, Y., Verbraecken, J., Partinen, M., Hedner, J., Saaresranta, T., Georgiev, O., et al. (2020). Pitolisant for daytime sleepiness in patients with obstructive sleep apnea who refuse continuous positive airway pressure treatment a randomized trial. American Journal of Respiratory and Critical Care Medicine, 201(9), 1135–1145.PubMedPubMedCentralCrossRef
58.
de Ruiter MHT, Apperloo RC, Milstein DMJ, de Lange J. Facial esthetics and subjective impairment assessed after maxillomandibular advancement surgery for patients with obstructive sleep apnea. Cranio - J Craniomandib Sleep Pract [Internet]. 2023;41(1):16–21. Available from: https://​doi.​org/​10.​1080/​08869634.​2020.​1801223
59.
Dusgun, E. S., Aslan, G. K., Abanoz, E. S., & Kiyan, E. (2022). respiratory muscle endurance in obesity hypoventilation syndrome. Respiratory Care, 67(5), 526–533.PubMedCrossRef
60.
Howook K, Soobin I, Park J Il, Yeongwook K, Sohn MK, Sungju J. Improvement of cognitive function after continuous positive airway pressure treatment for subacute stroke patients with obstructive sleep apnea: A randomized controlled trial. Brain Sci. 2019;9(10):1–13.
61.
Isetta, V., Negrín, M. A., Monasterio, C., Masa, J. F., Feu, N., Álvarez, A., et al. (2015). A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: A multicentre randomized controlled trial. Thorax, 70(11), 1054–1061.PubMedCrossRef
62.
Jenkinson, C., Stradling, J., & Petersen, S. (1997). Comparison of three measures of quality of life outcome in the evaluation of continuous positive airways pressure therapy for sleep apnoea. Journal of Sleep Research, 6(3), 199–204.PubMedCrossRef
63.
Chakravorty, I., Cayton, R. M., & Szczepura, A. (2002). Health utilities in evaluating intervention in the sleep apnoea/hypopnoea syndrome. European Respiratory Journal, 20(5), 1233–1238.PubMedCrossRef
64.
Kataoka, H., Miyatake, N., Ichikawa, H., Arakawa, Y., & Mori, Y. (2017). Relationship of locomotive syndrome with health-related quality of life among patients with obstructive sleep apnea syndrome. Journal of Physical Therapy Science, 29(7), 1129–1133.PubMedPubMedCentralCrossRef
65.
Moss, J., Tew, G. A., Copeland, R. J., Stout, M., Billings, C. G., Saxton, J. M., et al. (2024). Effects of a pragmatic lifestyle intervention for reducing body mass in obese adults with obstructive sleep apnoea: A randomized controlled trial. Biomed Research International. https://​doi.​org/​10.​1155/​2014/​102164CrossRef
66.
Pierobon, A., Vigorè, M., Taurino, E., Grassi, G., Torlaschi, V., Maffoni, M., et al. (2023). Subjective HRQoL in patients with sleep apnea syndrome who underwent PAP therapy in a rehabilitation setting: A longitudinal study. Journal Clinical Medicine, 12(5), 1907.CrossRef
67.
Weaver, T. E., Mathias, S. D., Crosby, R. D., Bron, M., Bujanover, S., Menno, D., et al. (2021). Relationship between sleep efficacy endpoints and measures of functional status and health-related quality of life in participants with narcolepsy or obstructive sleep apnea treated for excessive daytime sleepiness. Journal of Sleep Research, 30(3), 1–9.CrossRef
68.
Nadal, N., de Batlle, J., Barbé, F., Marsal, J. R., Sánchez-de-la-Torre, A., Tarraubella, N., et al. (2018). Predictors of CPAP compliance in different clinical settings: Primary care versus sleep unit. Sleep Breath., 22(1), 157–163.PubMedCrossRef
69.
Corral, J., Sanchez-Quiroga, M. A., Carmona-Bernal, C., Sanchez-Armengol, A., De La Torre, A. S., Duran-Cantolla, J., et al. (2017). Conventional polysomnography is not necessary for the management of most patients with suspected obstructive sleep apnea noninferiority, randomized controlled trial. American Journal of Respiratory and Critical Care Medicine, 196(9), 1181–1190.PubMedCrossRef
70.
Oemar M, Janssen B. EQ-5D-5L User Guide. 2013;(October).
71.
Marmot, M., Friel, S., Bell, R., Houweling, T. A., & Taylor, S. (2008). Closing the gap in a generation: Health equity through action on the social determinants of health. Lancet, 372(9650), 1661–1669.PubMedCrossRef
72.
Imrey, P. B. (2020). Limitations of Meta-analyses of Studies with High Heterogeneity. JAMA Network Open, 3(1), 2019–2021.CrossRef
73.
Suri, T. M., Ghosh, T., Mittal, S., Hadda, V., Madan, K., & Mohan, A. (2023). Systematic review and meta-analysis of the prevalence of obstructive sleep apnea in Indian adults. Sleep Medicine Reviews, 71(October), 2–6.
Metagegevens
Titel
Quality of life among obstructive sleep apnoea patients: a systematic review and meta-analysis of EQ-5D studies
Publicatiedatum
19-11-2024
Gepubliceerd in
Quality of Life Research
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-024-03828-4