Skip to main content
main-content
Top

Tip

Swipe om te navigeren naar een ander artikel

12-12-2017 | Uitgave 3/2018

Quality of Life Research 3/2018

Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

Tijdschrift:
Quality of Life Research > Uitgave 3/2018
Auteurs:
Axel Svedbom, Fredrik Borgström, Emma Hernlund, Oskar Ström, Vidmantas Alekna, Maria Luisa Bianchi, Patricia Clark, Manuel Díaz Curiel, Hans Peter Dimai, Mikk Jürisson, Anneli Uusküla, Margus Lember, Riina Kallikorm, Olga Lesnyak, Eugene McCloskey, Olga Ershova, Kerrie M. Sanders, Stuart Silverman, Marija Tamulaitiene, Thierry Thomas, Anna N. A. Tosteson, Bengt Jönsson, John A. Kanis
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11136-017-1748-5) contains supplementary material, which is available to authorized users.

Abstract

Introduction

The International Costs and Utilities Related to Osteoporotic fractures Study is a multinational observational study set up to describe the costs and quality of life (QoL) consequences of fragility fracture. This paper aims to estimate and compare QoL after hip, vertebral, and distal forearm fracture using time-trade-off (TTO), the EuroQol (EQ) Visual Analogue Scale (EQ-VAS), and the EQ-5D-3L valued using the hypothetical UK value set.

Methods

Data were collected at four time-points for five QoL point estimates: within 2 weeks after fracture (including pre-fracture recall), and at 4, 12, and 18 months after fracture. Health state utility values (HSUVs) were derived for each fracture type and time-point using the three approaches (TTO, EQ-VAS, EQ-5D-3L). HSUV were used to estimate accumulated QoL loss and QoL multipliers.

Results

In total, 1410 patients (505 with hip, 316 with vertebral, and 589 with distal forearm fracture) were eligible for analysis. Across all time-points for the three fracture types, TTO provided the highest HSUVs, whereas EQ-5D-3L consistently provided the lowest HSUVs directly after fracture. Except for 13–18 months after distal forearm fracture, EQ-5D-3L generated lower QoL multipliers than the other two methods, whereas no equally clear pattern was observed between EQ-VAS and TTO. On average, the most marked differences between the three approaches were observed immediately after the fracture.

Conclusions

The approach to derive QoL markedly influences the estimated QoL impact of fracture. Therefore the choice of approach may be important for the outcome and interpretation of cost-effectiveness analysis of fracture prevention.

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Podotherapeut Totaal

Binnen de bundel kunt u gebruik maken van boeken, tijdschriften, e-learnings, web-tv's en uitlegvideo's. BSL Podotherapeut Totaal is overal toegankelijk; via uw PC, tablet of smartphone.

Extra materiaal
Supplementary material 1 (DOCX 77 KB)
11136_2017_1748_MOESM1_ESM.docx
Supplementary material 2 (DOCX 12 KB)
11136_2017_1748_MOESM2_ESM.docx
Literatuur
Over dit artikel

Andere artikelen Uitgave 3/2018

Quality of Life Research 3/2018 Naar de uitgave