Top

Research on Child and Adolescent Psychopathology

Tip

Swipe om te navigeren naar een ander artikel

31-05-2023

Psychotic Vulnerability and its Associations with Clinical Characteristics in Adolescents with Obsessive-Compulsive Disorder

Auteurs: Davide Fausto Borrelli, Matti Cervin, Rebecca Ottoni, Carlo Marchesi, Matteo Tonna

Gepubliceerd in: Research on Child and Adolescent Psychopathology

Abstract

Compared to peers, children and adolescents with obsessive-compulsive disorder (OCD) are at increased risk of developing psychotic disorders. Yet very few studies have examined early indicators of psychosis in pediatric OCD. In the present study, 52 youth with a primary diagnosis of OCD (M_age = 15.66 [SD = 2.33], 59.6% girls) were interviewed using the Schizophrenia Proneness Instrument Child and Adolescent version (SPI-CY), which is a comprehensive clinical interview assessing both Cognitive–Perceptual basic symptoms (COPER) and high-risk criterion Cognitive Disturbances (COGDIS). Associations between COPER/COGDIS symptoms and demographic and clinical characteristics were examined. Findings showed that COPER or COGDIS symptoms were present in 44% of participants, with no significant difference between girls and boys. Psychotic vulnerability was associated with an earlier age of OCD onset, greater OCD severity, poorer insight, and more contamination/cleaning symptoms. Psychotic vulnerability was also strongly associated with worse psychosocial functioning. Findings suggest that early indicators of psychosis are frequent in pediatric OCD and associated with more severe OCD and poorer functioning. Research examining how psychotic vulnerability is associated with short- and long-term outcomes for youth with OCD is needed.

Abramovitch, A., Mittelman, A., Tankersley, A. P., Abramowitz, J. S., & Schweiger, A. (2015). Neuropsychological investigations in obsessive–compulsive disorder: A systematic review of methodological challenges. Psychiatry Research, 228(1), 112–120. https://doi.org/10.1016/j.psychres.2015.04.025. CrossRefPubMed

Abramowitz, J. S., Deacon, B. J., Olatunji, B. O., Wheaton, M. G., Berman, N. C., Losardo, D., Timpano, K. R., McGrath, P. B., Riemann, B. C., Adams, T., Björgvinsson, T., Storch, E. A., & Hale, L. R. (2010). Assessment of obsessive-compulsive symptom dimensions: Development and evaluation of the Dimensional Obsessive-Compulsive scale. Psychological assessment, 22(1), 180–198. https://doi.org/10.1037/a0018260. CrossRefPubMed

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (DSM-5) (5th ed.). Washington: American Psychiatric Association. CrossRef

Attademo, L., & Bernardini, F. (2021). Schizotypal personality disorder in clinical obsessive–compulsive disorder samples: A brief overview. CNS Spectrums, 26(5), 468–480. https://doi.org/10.1017/S1092852920001716. CrossRefPubMed

Averna, R., Pontillo, M., Demaria, F., Armando, M., Santonastaso, O., Pucciarini, M., Tata, M., Mancini, F., & Vicari, S. (2018). Prevalence and clinical significance of symptoms at Ultra High Risk for psychosis in children and adolescents with obsessive–compulsive disorder: Is there an Association with Global, Role, and Social Functioning? Brain Sciences, 8(10), 181. https://doi.org/10.3390/brainsci8100181. CrossRefPubMedPubMedCentral

Azen, R., & Budescu, D. (2003). The dominance analysis approach for comparing predictors in multiple regression. Psychological Methods, 8(2), 129–148. https://doi.org/10.1037/1082-989X.8.2.129. CrossRefPubMed

Barzilay, R., Patrick, A., Calkins, M. E., Moore, T. M., Wolf, D. H., Benton, T. D., Leckman, J. F., Gur, R. C., & Gur, R. E. (2019). Obsessive-compulsive symptomatology in Community Youth: Typical development or a red flag for psychopathology? Journal of the American Academy of Child & Adolescent Psychiatry, 58(2), 277–286e4. https://doi.org/10.1016/j.jaac.2018.06.038. CrossRef

Borrelli, D. F., Ottoni, R., Provettini, A., Morabito, C., Dell’Uva, L., Marchesi, C., & Tonna, M. (2022). A clinical investigation of psychotic vulnerability in early-onset obsessive–compulsive disorder through cognitive–perceptive basic symptoms. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-022-01543-0. CrossRefPubMed

Brown, H. M., Lester, K. J., Jassi, A., Heyman, I., & Krebs, G. (2015). Paediatric obsessive-compulsive disorder and depressive symptoms: Clinical Correlates and CBT Treatment Outcomes. Journal of abnormal child psychology, 43(5), 933–942. https://doi.org/10.1007/s10802-014-9943-0. CrossRefPubMed

Cederlöf, M., Lichtenstein, P., Larsson, H., Boman, M., Rück, C., Landén, M., & Mataix-Cols, D. (2015). Obsessive-compulsive disorder, psychosis, and bipolarity: A longitudinal cohort and multigenerational family study. Schizophrenia Bulletin, 41(5), 1076–1083. https://doi.org/10.1093/schbul/sbu169. CrossRefPubMed

Cervin, M. (2023). Sensory Processing Difficulties in children and adolescents with obsessive-compulsive and anxiety Disorders. Research on Child and Adolescent Psychopathology, 51(2), 223–232. https://doi.org/10.1007/s10802-022-00962-w. CrossRefPubMed

Cervin, M., Perrin, S., Olsson, E., Claesdotter-Knutsson, E., & Lindvall, M. (2021). Involvement of fear, incompleteness, and disgust during symptoms of pediatric obsessive–compulsive disorder. European Child & Adolescent Psychiatry, 30(2), 271–281. https://doi.org/10.1007/s00787-020-01514-7. CrossRef

Cervin, M., McNeel, M. M., Wilhelm, S., McGuire, J. F., Murphy, T. K., Small, B. J., Geller, D. A., & Storch, E. A. (2022a). Cognitive beliefs across the Symptom Dimensions of Pediatric Obsessive-Compulsive disorder: Type of Symptom matters. Behavior therapy, 53(2), 240–254. https://doi.org/10.1016/j.beth.2021.08.001. CrossRefPubMed

Cervin, M., Garcia-Delgar, B., Calvo, R., Ortiz, A. E., & Lazaro, L. (2022b). Symptom Dimension Breakpoints for the obsessive-compulsive inventory-child version (OCI-CV). Child Psychiatry & Human Development. https://doi.org/10.1007/s10578-021-01305-4. CrossRef

Cervin, M., Miguel, E. C., Güler, A. S., Ferrão, Y. A., Erdoğdu, A. B., Lazaro, L., Gökçe, S., Geller, D. A., Yulaf, Y., Başgül, Ş. S., Özcan, Ö., Karabekiroğlu, K., Fontenelle, L. F., Yazgan, Y., Storch, E. A., Leckman, J. F., do, Rosário, M. C., & Mataix-Cols, D. (2022c). Towards a definitive symptom structure of obsessive-compulsive disorder: a factor and network analysis of 87 distinct symptoms in 1366 individuals. Psychological medicine, 52(14), 3267–3279. https://doi.org/10.1017/S0033291720005437

Chen, M. H., Tsai, S. J., Liang, C. S., Cheng, C. M., Su, T. P., Chen, T. J., & Bai, Y. M. (2022). Diagnostic progression to schizophrenia in 35,255 patients with obsessive–compulsive disorder: A longitudinal follow-up study. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-021-01361-w. CrossRefPubMedPubMedCentral

Cheng, Y. F., Chen, V. C. H., Yang, Y. H., Chen, K. J., Lee, Y. C., & Lu, M. L. (2019). Risk of schizophrenia among people with obsessive-compulsive disorder: A nationwide population-based cohort study. Schizophrenia Research, 209, 58–63. https://doi.org/10.1016/j.schres.2019.05.024. CrossRefPubMed

Costas, J., Carrera, N., Alonso, P., Gurriarán, X., Segalàs, C., Real, E., López-Solà, C., Mas, S., Gassó, P., Domènech, L., Morell, M., Quintela, I., Lázaro, L., Menchón, J. M., Estivill, X., & Carracedo, Á. (2016). Exon-focused genome-wide association study of obsessive-compulsive disorder and shared polygenic risk with schizophrenia. Translational Psychiatry, 6(3), e768–e768. https://doi.org/10.1038/tp.2016.34. CrossRefPubMedPubMedCentral

Costello, E. J., Copeland, W., & Angold, A. (2011). Trends in psychopathology across the adolescent years: What changes when children become adolescents, and when adolescents become adults? Journal of Child Psychology and Psychiatry, 52(10), 1015–1025. https://doi.org/10.1111/j.1469-7610.2011.02446.x. CrossRefPubMed

Cunill, R., Vives, L., Pla, M., Usall, J., & Castells, X. (2023). Relationship between obsessive compulsive symptomatology and severity of psychotic symptoms in schizophrenia: Meta-analysis and meta-regression analysis. Schizophrenia Research, 251, 37–45. https://doi.org/10.1016/j.schres.2022.12.013. CrossRefPubMed

Dar, R., Kahn, D. T., & Carmeli, R. (2012). The relationship between sensory processing, childhood rituals and obsessive–compulsive symptoms. Journal of Behavior Therapy and Experimental Psychiatry, 43(1), 679–684. https://doi.org/10.1016/j.jbtep.2011.09.008. CrossRefPubMed

de Jong, Y., Boon, A. E., Gouw, D., van der Gaag, M., & Mulder, C. L. (2022). Improving screening methods for psychosis in an adolescent help-seeking population using the child Behavior Checklist (CBCL) and the Youth Self Report (YSR) versus the Prodromal questionnaire – 16 items version (PQ-16). Child and Adolescent Psychiatry and Mental Health, 16(1), 25. https://doi.org/10.1186/s13034-022-00459-w. CrossRefPubMedPubMedCentral

Faragian, S., Fuchs, C., Pashinian, A., Weizman, R., Weizman, A., & Poyurovsky, M. (2012). Age-of-onset of schizophrenic and obsessive-compulsive symptoms in patients with schizo-obsessive disorder. Psychiatry Research, 197(1–2), 19–22. https://doi.org/10.1016/j.psychres.2012.02.024. CrossRefPubMed

Ferrão, Y. A., Shavitt, R. G., Prado, H., Fontenelle, L. F., Malavazzi, D. M., de Mathis, M. A., Hounie, A. G., Miguel, E. C., & do Rosário, M. C. (2012). Sensory phenomena associated with repetitive behaviors in obsessive-compulsive disorder: An exploratory study of 1001 patients. Psychiatry Research, 197(3), 253–258. https://doi.org/10.1016/j.psychres.2011.09.017. CrossRefPubMed

First, M. B., Williams, J. B., Karg, R. S., & Spitzer, R. L. (2016). SCID-5-CV: Structured clinical interview for DSM-5 disorders: Clinician version. VA: American Psychiatric Association Publishing Arlington.

Foa, E. B., Coles, M., Huppert, J. D., Pasupuleti, R., Franklin, M. E., & March, J. (2010). Development and validation of a child version of the obsessive compulsive inventory. Behavior Therapy, 41(1), 121–132. https://doi.org/10.1016/j.beth.2009.02.001. CrossRefPubMed

Fu, X., Quan, W., Liu, L., Li, T., Dong, W., Wang, J., Tian, J., Yan, J., & Liao, J. (2022). Similarities and differences in brain activation between patients with Schizophrenia and obsessive-compulsive disorder: A Near-Infrared Spectroscopy Study. Frontiers in Psychiatry, 13, https://doi.org/10.3389/fpsyt.2022.853428.

Fusar-Poli, P., Borgwardt, S., Bechdolf, A., Addington, J., Riecher-Rössler, A., Schultze-Lutter, F., Keshavan, M., Wood, S., Ruhrmann, S., Seidman, L. J., Valmaggia, L., Cannon, T., Velthorst, E., de Haan, L., Cornblatt, B., Bonoldi, I., Birchwood, M., McGlashan, T., Carpenter, W., & Yung, A. (2013). The psychosis high-risk state. JAMA Psychiatry, 70(1), 107. https://doi.org/10.1001/jamapsychiatry.2013.269. CrossRefPubMedPubMedCentral

Fux, L., Walger, P., Schimmelmann, B. G., & Schultze-Lutter, F. (2013). The Schizophrenia Proneness Instrument, Child and Youth version (SPI-CY): Practicability and discriminative validity. Schizophrenia Research, 146(1–3), 69–78. https://doi.org/10.1016/j.schres.2013.02.014. CrossRefPubMed

Giersch, A., Lalanne, L., Corves, C., Seubert, J., Shi, Z., Foucher, J., & Elliott, M. A. (2009). Extended visual simultaneity thresholds in patients with Schizophrenia. Schizophrenia Bulletin, 35(4), 816–825. https://doi.org/10.1093/schbul/sbn016. CrossRefPubMed

Glenthøj, L. B., Bailey, B., Kristensen, T. D., Wenneberg, C., Hjorthøj, C., & Nordentoft, M. (2020). Basic symptoms influence real-life functioning and symptoms in individuals at high risk for psychosis. Acta Psychiatrica Scandinavica, 141(3), 231–240. https://doi.org/10.1111/acps.13117. CrossRefPubMed

Gur, R. C., Braff, D. L., Calkins, M. E., Dobie, D. J., Freedman, R., Green, M. F., Greenwood, T. A., Lazzeroni, L. C., Light, G. A., Nuechterlein, K. H., Olincy, A., Radant, A. D., Seidman, L. J., Siever, L. J., Silverman, J. M., Sprock, J., Stone, W. S., Sugar, C. A., Swerdlow, N. R., & Gur, R. E. (2015). Neurocognitive performance in family-based and case-control studies of schizophrenia. Schizophrenia Research, 163(1–3), 17–23. https://doi.org/10.1016/j.schres.2014.10.049. CrossRefPubMed

Hawco, C., Voineskos, A. N., Radhu, N., Rotenberg, D., Ameis, S., Backhouse, F. A., Semeralul, M., & Daskalakis, Z. J. (2017). Age and gender interactions in white matter of schizophrenia and obsessive compulsive disorder compared to non-psychiatric controls: Commonalities across disorders. Brain Imaging and Behavior, 11(6), 1836–1848. https://doi.org/10.1007/s11682-016-9657-8. CrossRefPubMed

Huang, M., Müller, C., & Gaynanova, I. (2021). latentcor: An R Package for estimating latent correlations from mixed data types. Journal of Open Source Software, 6(65), 3634. https://doi.org/10.21105/joss.03634. CrossRef

Huber, G., & Gross, G. (1989). The concept of basic symptoms in schizophrenic and schizoaffective psychoses. Recenti Progressi in Medicina, 80(12), 646–652. PubMed

Javitt, D. C., & Freedman, R. (2015). Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia. American Journal of Psychiatry, 172(1), 17–31. https://doi.org/10.1176/appi.ajp.2014.13121691.

Kovacs, M. (1992). Children’s depression inventory. Acta Paedopsychiatrica: International Journal of Child & Adolescent Psychiatry.

Lavallé, L., Bation, R., Dondé, C., Mondino, M., & Brunelin, J. (2020). Dissociable source-monitoring impairments in obsessive–compulsive disorder and schizophrenia. European Psychiatry, 63(1), e54. https://doi.org/10.1192/j.eurpsy.2020.48. CrossRefPubMedPubMedCentral

Lewin, A. B., Wu, M. S., Murphy, T. K., & Storch, E. A. (2015). Sensory over-responsivity in Pediatric Obsessive compulsive disorder. Journal of Psychopathology and Behavioral Assessment, 37(1), 134–143. https://doi.org/10.1007/s10862-014-9442-1. CrossRef

Mataix-Cols, D., Wooderson, S., Lawrence, N., Brammer, M. J., Speckens, A., & Phillips, M. L. (2004). Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder. Archives of general psychiatry, 61(6), 564–576. https://doi.org/10.1001/archpsyc.61.6.564. CrossRefPubMed

Meier, S. M., Petersen, L., Pedersen, M. G., Arendt, M. C. B., Nielsen, P. R., Mattheisen, M., Mors, O., & Mortensen, P. B. (2014). Obsessive-compulsive disorder as a risk factor for Schizophrenia. JAMA Psychiatry, 71(11), 1215. https://doi.org/10.1001/jamapsychiatry.2014.1011. CrossRefPubMed

Moritz, S., Claussen, M., Hauschildt, M., & Kellner, M. (2014). Perceptual Properties of Obsessive Thoughts are Associated with Low Insight in Obsessive-Compulsive disorder. Journal of Nervous & Mental Disease, 202(7), 562–565. https://doi.org/10.1097/NMD.0000000000000156. CrossRef

Moritz, S., Purdon, C., Jelinek, L., Chiang, B., & Hauschildt, M. (2018). If it is absurd, then why do you do it? The richer the obsessional experience, the more compelling the compulsion. Clinical Psychology & Psychotherapy, 25(2), 210–216. https://doi.org/10.1002/cpp.2155. CrossRef

Moulding, R., Anglim, J., Nedeljkovic, M., Doron, G., Kyrios, M., & Ayalon, A. (2011). The obsessive beliefs questionnaire (OBQ): Examination in nonclinical samples and development of a short version. Assessment, 18(3), 357–374. https://doi.org/10.1177/1073191110376490. CrossRefPubMed

Okamura, Y., Murahashi, Y., Umeda, Y., Misumi, T., Asami, T., Itokawa, M., Harima, H., Mizuno, M., Matsunaga, H., & Hishimoto, A. (2022a). Obsessive-Compulsive Disorder with Psychotic Features: Is It a Clinical Entity? Healthcare, 10(10), 1910. https://doi.org/10.3390/healthcare10101910

Ottoni, R., Pellegrini, C., Mora, L., Marchesi, C., & Tonna, M. (2022). Psychopathology of insight in obsessive–compulsive disorder. Current Psychology. https://doi.org/10.1007/s12144-022-02806-8. CrossRef

Pelizza, L., & Pupo, S. (2015). Basic symptoms in obsessive-compulsive disorder. Journal of Psychopathology, 21, 62–71.

Pelizza, L., Quattrone, E., Leuci, E., Paulillo, G., Azzali, S., Pupo, S., & Pellegrini, P. (2022). Anxious-depressive symptoms after a first episode of schizophrenia: Response to treatment and psychopathological considerations from the 2-year “Parma Early Psychosis” program. Psychiatry research, 317, 114887. https://doi.org/10.1016/j.psychres.2022.114887. CrossRefPubMed

Peris, T. S., Bergman, R. L., Asarnow, J. R., Langley, A., McCracken, J. T., & Piacentini, J. (2010). Clinical and cognitive correlates of depressive symptoms among youth with obsessive compulsive disorder. Journal of clinical child and adolescent psychology: the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53, 39(5), 616–626. https://doi.org/10.1080/15374416.2010.501285

Phillips, L. J., Yung, A. R., McGorry, P. D., & Australian (2000). & New Zealand Journal of Psychiatry, 34(2_suppl), S164–S169. https://doi.org/10.1080/000486700239 CrossRef

Poletti, M., Gebhardt, E., & Raballo, A. (2021). Along the fringes of Agency: Neurodevelopmental account of the obsessive mind. CNS Spectrums, 1–4. https://doi.org/10.1017/S1092852921000560.

Poyurovsky, M., Faragian, S., Shabeta, A., & Kosov, A. (2008). Comparison of clinical characteristics, co-morbidity and pharmacotherapy in adolescent schizophrenia patients with and without obsessive–compulsive disorder. Psychiatry Research, 159(1–2), 133–139. https://doi.org/10.1016/j.psychres.2007.06.010. CrossRefPubMed

Poyurovsky, M., Zohar, J., Glick, I., Koran, L. M., Weizman, R., Tandon, R., & Weizman, A. (2012). Obsessive-compulsive symptoms in schizophrenia: Implications for future psychiatric classifications. Comprehensive Psychiatry, 53(5), 480–483. https://doi.org/10.1016/j.comppsych.2011.08.009. CrossRefPubMed

Prado, H. S., Rosário, M. C., do, Lee, J., Hounie, A. G., Shavitt, R. G., & Miguel, E. C. (2008). Sensory phenomena in obsessive-compulsive disorder and Tic Disorders: A review of the literature. CNS Spectrums, 13(5), 425–432. https://doi.org/10.1017/S1092852900016606. CrossRefPubMed

Preti, A., Meneghelli, A., Poletti, M., & Raballo, A. (2022). Through the prism of comorbidity: A strategic rethinking of early intervention in obsessive-compulsive disorder. Schizophrenia Research, 239, 128–133. https://doi.org/10.1016/j.schres.2021.11.038. CrossRefPubMed

Pruessner, M., Iyer, S. N., Faridi, K., Joober, R., & Malla, A. K. (2011). Stress and protective factors in individuals at ultra-high risk for psychosis, first episode psychosis and healthy controls. Schizophrenia research, 129(1), 29–35. https://doi.org/10.1016/j.schres.2011.03.022. CrossRefPubMed

Qin, H., Samuels, J. F., Wang, Y., Zhu, Y., Grados, M. A., Riddle, M. A., Greenberg, B. D., Knowles, J. A., Fyer, A. J., McCracken, J. T., Murphy, D. L., Rasmussen, S. A., Cullen, B. A., Piacentini, J., Geller, D., Stewart, S. E., Pauls, D., Bienvenu, O. J., Goes, F. S., & Shugart, Y. Y. (2016). Whole-genome association analysis of treatment response in obsessive-compulsive disorder. Molecular Psychiatry, 21(2), 270–276. https://doi.org/10.1038/mp.2015.32. CrossRefPubMed

Rasmussen, A. R., Nordgaard, J., & Parnas, J. (2020). Schizophrenia-spectrum psychopathology in obsessive–compulsive disorder: An empirical study. European Archives of Psychiatry and Clinical Neuroscience, 270(8), 993–1002. https://doi.org/10.1007/s00406-019-01022-z. CrossRefPubMed

Röhlinger, J., Wulf, F., Fieker, M., & Moritz, S. (2015). Sensory properties of obsessive thoughts in OCD and the relationship to psychopathology. Psychiatry Research, 230(2), 592–596. https://doi.org/10.1016/j.psychres.2015.10.009. CrossRefPubMed

Scahill, L., Riddle, M. A., Mcswiggin-Hardin, M., Ort, S. I., King, R. A., Goodman, W. K., Cicchetti, D., & Leckman, J. F. (1997). Children’s Yale-Brown Obsessive compulsive scale: Reliability and validity. Journal of the American Academy of Child & Adolescent Psychiatry, 36(6), 844–852. https://doi.org/10.1097/00004583-199706000-00023. CrossRef

Schirmbeck, F., Swets, M., Meijer, C. J., Zink, M., & de Haan, L. (2018). Obsessive–compulsive symptoms and overall psychopathology in psychotic disorders: Longitudinal assessment of patients and siblings. European Archives of Psychiatry and Clinical Neuroscience, 268(3), 279–289. https://doi.org/10.1007/s00406-016-0751-0. CrossRefPubMed

Schultze-Lutter, F., & Theodoridou, A. (2017). The concept of basic symptoms: Its scientific and clinical relevance. World Psychiatry, 16(1), 104–105. https://doi.org/10.1002/wps.20404. CrossRefPubMedPubMedCentral

Schultze-Lutter, F., Ruhrmann, S., & Klosterkötter, J. (2006). Can schizophrenia be predicted phenomenologically? Evolving psychosis. Different stages, different treatments (1st ed., pp. 104–123). Routledge.

Schultze-Lutter, F., Ruhrmann, S., Berning, J., Maier, W., & Klosterkotter, J. (2010). Basic symptoms and Ultrahigh Risk Criteria: Symptom Development in the initial Prodromal State. Schizophrenia Bulletin, 36(1), 182–191. https://doi.org/10.1093/schbul/sbn072. CrossRefPubMed

Schultze-Lutter, F., Marshall, M., & Koch, E. (2012a). Schizophrenia Proneness Instrument, Child and Youth Version (SPI-CY). Giovanni Fioriti Editore SRl.

Schultze-Lutter, F., Ruhrmann, S., Fusar-Poli, P., Bechdolf, A., Schimmelmann, G., B., & Klosterkotter, J. (2012b). Basic symptoms and the prediction of First-Episode Psychosis. Current Pharmaceutical Design, 18(4), 351–357. https://doi.org/10.2174/138161212799316064. CrossRefPubMed

Schultze-Lutter, F., Michel, C., Schmidt, S. J., Schimmelmann, B. G., Maric, N. P., Salokangas, R. K. R., Riecher-Rössler, A., van der Gaag, M., Nordentoft, M., Raballo, A., Meneghelli, A., Marshall, M., Morrison, A., Ruhrmann, S., & Klosterkötter, J. (2015). EPA guidance on the early detection of clinical high risk states of psychoses. European Psychiatry, 30(3), 405–416. https://doi.org/10.1016/j.eurpsy.2015.01.010. CrossRefPubMed

Schultze-Lutter, F., Walger, P., Franscini, M., Traber-Walker, N., Osman, N., Walger, H., Schimmelmann, B. G., Flückiger, R., & Michel, C. (2022). Clinical high-risk criteria of psychosis in 8–17-year-old community subjects and inpatients not suspected of developing psychosis. World Journal of Psychiatry, 12(3), 425–449. https://doi.org/10.5498/wjp.v12.i3.425. CrossRefPubMedPubMedCentral

Scotti-Muzzi, E., & Saide, O. L. (2017). Schizo-obsessive spectrum disorders: An update. CNS Spectrums, 22(3), 258–272. https://doi.org/10.1017/S1092852916000390. CrossRefPubMed

Shaffer, D. (1983). A children’s Global Assessment Scale (CGAS). Archives of General Psychiatry, 40(11), 1228. https://doi.org/10.1001/archpsyc.1983.01790100074010. CrossRefPubMed

Smoller, J. W., Andreassen, O. A., Edenberg, H. J., Faraone, S., Glatt, S. J., & Kendler, K. S. (2019). Psychiatric genetics and the structure of psychopathology. Molecular Psychiatry, 24(3), 409–420. https://doi.org/10.1038/s41380-017-0010-4. CrossRefPubMed

Swets, M., Dekker, J., van Emmerik-van Oortmerssen, K., Smid, G. E., Smit, F., de Haan, L., & Schoevers, R. A. (2014). The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates. Schizophrenia Research, 152(2–3), 458–468. https://doi.org/10.1016/j.schres.2013.10.033. CrossRefPubMed

Tonna, M., Ottoni, R., Paglia, F., Ossola, P., de Panfilis, C., & Marchesi, C. (2016a). Obsessive–compulsive symptom severity in schizophrenia: A Janus Bifrons effect on functioning. European Archives of Psychiatry and Clinical Neuroscience, 266(1), 63–69. https://doi.org/10.1007/s00406-015-0608-y. CrossRefPubMed

Tonna, M., Ottoni, R., Paglia, F., Ossola, P., de Panfilis, C., & Marchesi, C. (2016b). Obsessive–compulsive symptoms interact with disorganization in influencing social functioning in schizophrenia. Schizophrenia Research, 171(1–3), 35–41. https://doi.org/10.1016/j.schres.2016.01.002. CrossRefPubMed

Tonna, M., Ottoni, R., Paglia, F., Monici, A., Ossola, P., Panfilis, D. E., C., & Marchesi, C. (2016c). Obsessive-compulsive symptoms in Schizophrenia and in obsessive-compulsive disorder: Differences and similarities. Journal of psychiatric practice, 22(2), 111–116. https://doi.org/10.1097/PRA.0000000000000131. CrossRefPubMed

Tonna, M., Marchesi, C., & Parmigiani, S. (2019). The biological origins of rituals: An interdisciplinary perspective. Neuroscience And Biobehavioral Reviews, 98, 95–106. https://doi.org/10.1016/j.neubiorev.2018.12.031. CrossRefPubMed

Tonna, M., Ponzi, D., Palanza, P., Marchesi, C., & Parmigiani, S. (2020). Proximate and ultimate causes of ritual behavior. Behavioural Brain Research, 393, 112772. https://doi.org/10.1016/j.bbr.2020.112772. CrossRefPubMed

Tonna, M., Ottoni, R., Pellegrini, C., Mora, L., Gambolo, L., di Donna, A., Parmigiani, S., & Marchesi, C. (2022). The motor profile of obsessive-compulsive rituals: Psychopathological and evolutionary implications. CNS Spectrums, 1–30. https://doi.org/10.1017/S1092852922000165.

Weidle, B., Ivarsson, T., Asbahr, F. R., Calvo, R., Mataix-Cols, D., Rynn, M. A., & Storch, E. A. (2021). Specialty knowledge and competency standards for pharmacotherapy for pediatric obsessive-compulsive disorder. Psychiatry Research, 299, 113858. https://doi.org/10.1016/j.psychres.2021.113858. CrossRefPubMed

Williams, M. T., Mugno, B., Franklin, M., & Faber, S. (2013). Symptom dimensions in obsessive-compulsive disorder: Phenomenology and treatment outcomes with exposure and ritual prevention. Psychopathology, 46(6), 365–376. https://doi.org/10.1159/000348582. CrossRefPubMed

Yung, A. R., Phillips, L. J., McGorry, P. D., McFarlane, C. A., Francey, S., Harrigan, S., Patton, G. C., & Jackson, H. J. (1998). Prediction of psychosis. British Journal of Psychiatry, 172(S33), 14–20. https://doi.org/10.1192/S0007125000297602. CrossRef

Zhou, T., Baytunca, B., Yu, X., & Öngür, D. (2016). Schizo-Obsessive disorder: The Epidemiology, diagnosis, and treatment of Comorbid Schizophrenia and OCD. Current Treatment Options in Psychiatry, 3(3), 235–245. https://doi.org/10.1007/s40501-016-0085-6. CrossRef

Titel: Psychotic Vulnerability and its Associations with Clinical Characteristics in Adolescents with Obsessive-Compulsive Disorder
Auteurs: Davide Fausto Borrelli
Matti Cervin
Rebecca Ottoni
Carlo Marchesi
Matteo Tonna
Publicatiedatum: 31-05-2023
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-023-01089-2

Bohn Stafleu van Loghum

Tip

Swipe om te navigeren naar een ander artikel

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen