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20-11-2018 | Uitgave 3/2019

Quality of Life Research 3/2019

Psychometric properties of the Quality of Life Inventory-Disability (QI-Disability) measure

Quality of Life Research > Uitgave 3/2019
Jenny Downs, Peter Jacoby, Helen Leonard, Amy Epstein, Nada Murphy, Elise Davis, Dinah Reddihough, Andrew Whitehouse, Katrina Williams
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The online version of this article (https://​doi.​org/​10.​1007/​s11136-018-2057-3) contains supplementary material, which is available to authorized users.



Children with intellectual disability encounter daily challenges beyond those captured in current quality of life measures. This study evaluated a new parent-report measure for children with intellectual disability, the Quality of Life Inventory-Disability (QI-Disability).


QI-Disability was administered to 253 primary caregivers of children (aged 5–18 years) with intellectual disability across four diagnostic groups: Rett syndrome, Down syndrome, cerebral palsy or autism spectrum disorder. Exploratory and confirmatory factor analyses were conducted and goodness of fit of the factor structure assessed. Associations between QI-Disability scores, and diagnostic and age groups were examined with linear regression.


Six domains were identified: physical health, positive emotions, negative emotions, social interaction, leisure and the outdoors, and independence. Goodness-of-fit statistics were satisfactory and similar for the whole sample and when the sample was split by ability to walk or talk. On 100 point scales and compared to Rett syndrome, children with Down syndrome had higher leisure and the outdoors (coefficient 10.6, 95% CI 3.4,17.8) and independence (coefficient 29.7, 95% CI 22.9, 36.5) scores, whereas children with autism spectrum disorder had lower social interaction scores (coefficient − 12.8, 95% CI − 19.3, − 6.4). Scores for positive emotions (coefficient − 6.1, 95% CI − 10.7, − 1.6) and leisure and the outdoors (coefficient 5.4, 95% CI − 10.6, − 0.1) were lower for adolescents compared with children.


Initial evaluation suggests that QI-Disability is a reliable and valid measure of quality of life across the spectrum of intellectual disability. It has the potential to allow clearer identification of support needs and measure responsiveness to interventions.

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