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Gepubliceerd in: Journal of Abnormal Child Psychology 6/2013

01-08-2013

Psychiatric Symptom Impairment in Children with Autism Spectrum Disorders

Auteurs: Aaron J. Kaat, Kenneth D. Gadow, Luc Lecavalier

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 6/2013

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Abstract

The general aim of this study was to examine the relation of psychiatric symptom-induced impairment with other common parameters of mental health in children with autism spectrum disorder (ASD). Prevalence rates are used to illustrate the implications of different criteria for caseness. Parents/teachers completed DSM-IV-referenced rating scales for 6–12 year old children with ASD (N = 115), the majority of whom were boys (86 %). Most children were rated by parents (81 %) or teachers (86 %) as being socially or academically impaired by symptoms of at least one psychiatric disorder. The most common impairing conditions (parent/teacher) were attention-deficit/hyperactivity disorder (67 %/71 %), oppositional defiant disorder (35 %/33 %), and anxiety disorder (47 %/34 %), and the combined rates based on either informant were generally much higher. Agreement between symptom cutoff and impairment cutoff was acceptable for most disorders. A larger percentage of youth were impaired by psychiatric symptoms than met symptom cutoff criteria, and the discrepancy between impairment cutoff and clinical cutoff (impairment cutoff plus symptom cutoff) was even greater. Impairment was moderately to highly correlated with both number and severity of symptoms. Parents’ and teachers’ ratings indicated little agreement as to whether a child was impaired. Findings for youth with ASD were similar to non ASD child psychiatry outpatient referrals, but clearly different in several ways from comparable studies of community-based samples.
Literatuur
go back to reference Altman, D. G. (1997). Practical statistics for medical research. Boca Raton: Chapman & Hall. Altman, D. G. (1997). Practical statistics for medical research. Boca Raton: Chapman & Hall.
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR. Washington, DC: Author. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR. Washington, DC: Author.
go back to reference Angold, A., Costello, E. J., Farmer, E. M. Z., Burns, B. J., & Erkanli, A. (1999). Impaired but undiagnosed. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 129–137. PubMedCrossRef Angold, A., Costello, E. J., Farmer, E. M. Z., Burns, B. J., & Erkanli, A. (1999). Impaired but undiagnosed. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 129–137. PubMedCrossRef
go back to reference Bird, H. R., Yager, T. J., Steghezza, B., Gould, M. S., Canino, G., & Rubio-Stipec, M. (1990). Impairment in the epidemiological measurement of childhood psychopathology in the community. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 796–803. PubMedCrossRef Bird, H. R., Yager, T. J., Steghezza, B., Gould, M. S., Canino, G., & Rubio-Stipec, M. (1990). Impairment in the epidemiological measurement of childhood psychopathology in the community. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 796–803. PubMedCrossRef
go back to reference Bird, H. R., Davies, M., Fisher, P., Narrow, W. E., Jensen, P. S., Hoven, C., et al. (2000). How specific is specific impairment? Journal of the American Academy of Child and Adolescent Psychiatry, 39, 1182–1189. PubMedCrossRef Bird, H. R., Davies, M., Fisher, P., Narrow, W. E., Jensen, P. S., Hoven, C., et al. (2000). How specific is specific impairment? Journal of the American Academy of Child and Adolescent Psychiatry, 39, 1182–1189. PubMedCrossRef
go back to reference Bird, R. H., Canino, G. J., Davies, M., Ramirez, R., Chavez, L., Duarte, C., et al. (2005). The Brief Impairment Scale (BIS): a multidimensional scale of functional impairment for children and adolescent. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 699–707. PubMedCrossRef Bird, R. H., Canino, G. J., Davies, M., Ramirez, R., Chavez, L., Duarte, C., et al. (2005). The Brief Impairment Scale (BIS): a multidimensional scale of functional impairment for children and adolescent. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 699–707. PubMedCrossRef
go back to reference Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Mahwah: Lawrence Erlbaum. Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Mahwah: Lawrence Erlbaum.
go back to reference De Los Reyes, A. (2011). More than measurement error: discovering meaning behind informant discrepancies in clinical assessments of children and adolescents. Journal of Clinical Child and Adolescent Psychology, 40, 1–9. PubMedCrossRef De Los Reyes, A. (2011). More than measurement error: discovering meaning behind informant discrepancies in clinical assessments of children and adolescents. Journal of Clinical Child and Adolescent Psychology, 40, 1–9. PubMedCrossRef
go back to reference DeVincent, C. J., & Gadow, K. D. (2009). Relative clinical utility of three child symptom Inventory-4 scoring algorithms for differentiating children with autism spectrum disorder versus attention-deficit hyperactivity disorder. Autism Research, 2, 312–321. PubMed DeVincent, C. J., & Gadow, K. D. (2009). Relative clinical utility of three child symptom Inventory-4 scoring algorithms for differentiating children with autism spectrum disorder versus attention-deficit hyperactivity disorder. Autism Research, 2, 312–321. PubMed
go back to reference Drabick, D. A. G., & Gadow, K. D. (2012). Deconstructing oppositional defiant disorder: clinic-based evidence for an anger/irritability phenotype. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 384–393. PubMedCrossRef Drabick, D. A. G., & Gadow, K. D. (2012). Deconstructing oppositional defiant disorder: clinic-based evidence for an anger/irritability phenotype. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 384–393. PubMedCrossRef
go back to reference Gadow, K. D. (2012). Schizophrenia spectrum and attention-deficit/hyperactivity disorder symptoms in autism spectrum disorder and controls. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1076–1084. PubMedCrossRef Gadow, K. D. (2012). Schizophrenia spectrum and attention-deficit/hyperactivity disorder symptoms in autism spectrum disorder and controls. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1076–1084. PubMedCrossRef
go back to reference Gadow, K. D., & DeVincent, C. J. (2012). Comparison of children with autism spectrum disorder with and without schizophrenia spectrum traits: Gender, season of birth, and mental health risk factors. Journal of Autism and Developmental Disorders, 42, 2285–2296. PubMedCrossRef Gadow, K. D., & DeVincent, C. J. (2012). Comparison of children with autism spectrum disorder with and without schizophrenia spectrum traits: Gender, season of birth, and mental health risk factors. Journal of Autism and Developmental Disorders, 42, 2285–2296. PubMedCrossRef
go back to reference Gadow, K. D., & Drabick, D. A. G. (2012). Anger and irritability symptoms among youth with ODD: Cross-informant versus source-exclusive syndromes. Journal of Abnormal Child Psychology, 40, 1073–1085. PubMedCrossRef Gadow, K. D., & Drabick, D. A. G. (2012). Anger and irritability symptoms among youth with ODD: Cross-informant versus source-exclusive syndromes. Journal of Abnormal Child Psychology, 40, 1073–1085. PubMedCrossRef
go back to reference Gadow, K. D., & Sprafkin, J. (2005). Child and Adolescent Symptom Inventory–4R. Stony Brook: Checkmate Plus. Gadow, K. D., & Sprafkin, J. (2005). Child and Adolescent Symptom Inventory–4R. Stony Brook: Checkmate Plus.
go back to reference Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism, 9, 392–415. PubMedCrossRef Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism, 9, 392–415. PubMedCrossRef
go back to reference Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2006). ADHD symptom subtypes in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders, 36, 271–283. PubMedCrossRef Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2006). ADHD symptom subtypes in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders, 36, 271–283. PubMedCrossRef
go back to reference Gadow, K. D., Schwartz, J., DeVincent, C., Strong, G., & Cuva, S. (2008). Clinical utility of autism spectrum disorder scoring algorithms for the child symptom Inventory. Journal of Autism and Developmental Disorders, 38, 419–427. PubMedCrossRef Gadow, K. D., Schwartz, J., DeVincent, C., Strong, G., & Cuva, S. (2008). Clinical utility of autism spectrum disorder scoring algorithms for the child symptom Inventory. Journal of Autism and Developmental Disorders, 38, 419–427. PubMedCrossRef
go back to reference Gadow, K. D., Angelidou, K., Chernoff, M., Williams, P. L., Heston, J., Hodge, J., et al. (2012a). Longitudinal study of emerging mental health concerns in youth perinatally-infected with HIV and peer comparisons. Journal of Developmental and Behavioral Pediatrics, 33, 456–468. CrossRef Gadow, K. D., Angelidou, K., Chernoff, M., Williams, P. L., Heston, J., Hodge, J., et al. (2012a). Longitudinal study of emerging mental health concerns in youth perinatally-infected with HIV and peer comparisons. Journal of Developmental and Behavioral Pediatrics, 33, 456–468. CrossRef
go back to reference Gadow, K. D., Guttmann-Steinmetz, S., Rieffe, C., & DeVincent, C. J. (2012b). Depression symptoms in boys with autism spectrum disorder and comparison samples. Journal of Autism and Developmental Disorders, 42, 1353–1363. PubMedCrossRef Gadow, K. D., Guttmann-Steinmetz, S., Rieffe, C., & DeVincent, C. J. (2012b). Depression symptoms in boys with autism spectrum disorder and comparison samples. Journal of Autism and Developmental Disorders, 42, 1353–1363. PubMedCrossRef
go back to reference Gadow, K.D., Kaat, A.J., & Lecavalier, L. (in press). Relation of symptom-induced impairment with other psychiatric illness parameters in clinic-referred youth. Journal of Child Psychology and Psychiatry. Gadow, K.D., Kaat, A.J., & Lecavalier, L. (in press). Relation of symptom-induced impairment with other psychiatric illness parameters in clinic-referred youth. Journal of Child Psychology and Psychiatry.
go back to reference Gathje, R. A., Lewandowski, L. J., & Gordon, M. (2008). The role of impairment in the diagnosis of ADHD. Journal of Attention Disorders, 11, 529–537. PubMed Gathje, R. A., Lewandowski, L. J., & Gordon, M. (2008). The role of impairment in the diagnosis of ADHD. Journal of Attention Disorders, 11, 529–537. PubMed
go back to reference Gordon, M., Antshel, K., Faraone, S., Barkley, R., Lewandowski, L., Hudziak, J. J., et al. (2006). Symptoms versus impairment: the case for respecting DSM-IV’s criterion D. Journal of Attention Disorders, 9, 465–475. PubMedCrossRef Gordon, M., Antshel, K., Faraone, S., Barkley, R., Lewandowski, L., Hudziak, J. J., et al. (2006). Symptoms versus impairment: the case for respecting DSM-IV’s criterion D. Journal of Attention Disorders, 9, 465–475. PubMedCrossRef
go back to reference Guttmann-Steinmetz, S., Gadow, K. D., DeVincent, C. J., & Crowell, J. (2010). Anxiety symptoms in boys with autism spectrum disorder, attention-deficit hyperactivity disorder, or chronic multiple tic disorder and community controls. Journal of Autism and Developmental Disorders, 40, 1006–1016. PubMedCrossRef Guttmann-Steinmetz, S., Gadow, K. D., DeVincent, C. J., & Crowell, J. (2010). Anxiety symptoms in boys with autism spectrum disorder, attention-deficit hyperactivity disorder, or chronic multiple tic disorder and community controls. Journal of Autism and Developmental Disorders, 40, 1006–1016. PubMedCrossRef
go back to reference Kraemer, H. C., Kupfer, D. J., Clarke, D. E., Narrow, W. E., & Regier, D. A. (2012). DSM-5: how reliable is reliable enough? The American Journal of Psychiatry, 169, 13–15. PubMedCrossRef Kraemer, H. C., Kupfer, D. J., Clarke, D. E., Narrow, W. E., & Regier, D. A. (2012). DSM-5: how reliable is reliable enough? The American Journal of Psychiatry, 169, 13–15. PubMedCrossRef
go back to reference Lecavalier, L., Leone, S., & Wiltz, J. (2006). The impact of behaviour problems on caregiver stress in young people with autism spectrum disorders. Journal of Intellectual Disability Research, 50, 172–183. PubMedCrossRef Lecavalier, L., Leone, S., & Wiltz, J. (2006). The impact of behaviour problems on caregiver stress in young people with autism spectrum disorders. Journal of Intellectual Disability Research, 50, 172–183. PubMedCrossRef
go back to reference Lecavalier, L., Gadow, K. D., DeVincent, C. J., & Edwards, M. C. (2009). Validation of DSM-IV model of psychiatric syndromes in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 278–289. PubMedCrossRef Lecavalier, L., Gadow, K. D., DeVincent, C. J., & Edwards, M. C. (2009). Validation of DSM-IV model of psychiatric syndromes in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 278–289. PubMedCrossRef
go back to reference Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849–861. PubMedCrossRef Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849–861. PubMedCrossRef
go back to reference Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The Autism Diagnostic Observation Schedule—Generic: a standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223. PubMedCrossRef Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The Autism Diagnostic Observation Schedule—Generic: a standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223. PubMedCrossRef
go back to reference Mandell, D. S., Morales, K. H., Marcus, S. C., Stahmer, A. C., Doshi, J., & Polsky, D. E. (2012). Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics, 121, 441–448. CrossRef Mandell, D. S., Morales, K. H., Marcus, S. C., Stahmer, A. C., Doshi, J., & Polsky, D. E. (2012). Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics, 121, 441–448. CrossRef
go back to reference Rapee, R. M., Bőgels, S. M., van der Sluis, C. M., Craske, M. G., & Ollendick, T. (2012). Annual research review: conceptualising functional impairment in children and adolescents. Journal of Child Psychology and Psychiatry, 53, 454–468. PubMedCrossRef Rapee, R. M., Bőgels, S. M., van der Sluis, C. M., Craske, M. G., & Ollendick, T. (2012). Annual research review: conceptualising functional impairment in children and adolescents. Journal of Child Psychology and Psychiatry, 53, 454–468. PubMedCrossRef
go back to reference Rommelse, N. N. J., Geurts, H. M., Franke, B., Buitelaar, J. K., & Hartman, C. A. (2011). A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes. Neuroscience and Biobehavioral Reviews, 35, 1363–1396. PubMedCrossRef Rommelse, N. N. J., Geurts, H. M., Franke, B., Buitelaar, J. K., & Hartman, C. A. (2011). A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes. Neuroscience and Biobehavioral Reviews, 35, 1363–1396. PubMedCrossRef
go back to reference Shaffer, D., Gould, M. S., Brasic, J., Ambrosini, P., Fisher, P., Bird, H., et al. (1984). A children’s global assessment scale (CGAS). Archives of General Psychiatry, 40, 228–231. Shaffer, D., Gould, M. S., Brasic, J., Ambrosini, P., Fisher, P., Bird, H., et al. (1984). A children’s global assessment scale (CGAS). Archives of General Psychiatry, 40, 228–231.
go back to reference Shaffer, D., Fisher, P., Lucas, C. P., Dulcan, M. K., & Schwab-Stone, M. E. (2000). NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 28–38. PubMedCrossRef Shaffer, D., Fisher, P., Lucas, C. P., Dulcan, M. K., & Schwab-Stone, M. E. (2000). NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 28–38. PubMedCrossRef
go back to reference Siegel, M., & Beaulieu, A. A. (2012). Psychotropic medications in children with autism spectrum disorders: a systematic review and synthesis for evidence-based practice. Journal of Autism and Developmental Disorders, 42, 1592–1605. PubMedCrossRef Siegel, M., & Beaulieu, A. A. (2012). Psychotropic medications in children with autism spectrum disorders: a systematic review and synthesis for evidence-based practice. Journal of Autism and Developmental Disorders, 42, 1592–1605. PubMedCrossRef
go back to reference Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929. PubMedCrossRef Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929. PubMedCrossRef
go back to reference Sprafkin, J., Steinberg, E.A., Gadow, K.D., & Drabick, D.A.G. (2013). Agreement among categorical, dimensional, and impairment criteria for ADHD and common comorbidities. Journal of Attention Disorders. Published online February 11, 2013. Sprafkin, J., Steinberg, E.A., Gadow, K.D., & Drabick, D.A.G. (2013). Agreement among categorical, dimensional, and impairment criteria for ADHD and common comorbidities. Journal of Attention Disorders. Published online February 11, 2013.
go back to reference Sverd, J. (2003). Psychiatric disorders in individuals with pervasive developmental disorder. Journal of Psychiatric Practice, 9, 111–127. PubMedCrossRef Sverd, J. (2003). Psychiatric disorders in individuals with pervasive developmental disorder. Journal of Psychiatric Practice, 9, 111–127. PubMedCrossRef
go back to reference Szatmari, P., Archer, L., Fisman, S., & Steiner, D. L. (1994). Parent and teacher agreement in the assessment of pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 703–717. PubMedCrossRef Szatmari, P., Archer, L., Fisman, S., & Steiner, D. L. (1994). Parent and teacher agreement in the assessment of pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 703–717. PubMedCrossRef
go back to reference Wagner, A., Lecavalier, L., Arnold, L. E., Aman, M. G., Scahill, L., Stigler, K. A., et al. (2007). Developmental Disabilities Modification of Children’s Global Assessment Scale (DD-CGAS). Biological Psychiatry, 61, 504–511. PubMedCrossRef Wagner, A., Lecavalier, L., Arnold, L. E., Aman, M. G., Scahill, L., Stigler, K. A., et al. (2007). Developmental Disabilities Modification of Children’s Global Assessment Scale (DD-CGAS). Biological Psychiatry, 61, 504–511. PubMedCrossRef
go back to reference Witwer, A. N., & Lecavalier, L. (2010). Validity of comorbid psychiatric disorders in youngsters with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22, 367–380. CrossRef Witwer, A. N., & Lecavalier, L. (2010). Validity of comorbid psychiatric disorders in youngsters with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22, 367–380. CrossRef
Metagegevens
Titel
Psychiatric Symptom Impairment in Children with Autism Spectrum Disorders
Auteurs
Aaron J. Kaat
Kenneth D. Gadow
Luc Lecavalier
Publicatiedatum
01-08-2013
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 6/2013
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-013-9739-7