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01-02-2020 | Original Article

Psychiatric Disorders in the Adolescent Offspring of Mothers with Thyroid Problems During Pregnancy

Auteurs: Jacob Young, Calan Savoy, Ian Colman, Mark Ferro, Ryan J. Van Lieshout

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 3/2020

Abstract

Maternal thyroid problems during pregnancy have been linked to neurocognitive impairments in children. While studies suggest that disorders of maternal thyroid function during pregnancy are associated with symptoms of mental health problems in children, little is known about the risk of clinically significant psychiatric disorders in adolescence. A sample of 2451 Canadian adolescents enrolled in the Ontario Child Health Study completed the Mini International Neuropsychiatric Interview for Children and Adolescents at 12–17 years of age. Their mothers self-reported thyroid problems during pregnancy. Gestational thyroid problems were associated with offspring oppositional defiant disorder (ODD; OR 3.73; 95% CI 1.69–8.24), conduct disorder (CD; OR 12.95; 95% CI 5.12–32.75), and social anxiety disorder (SAD; OR 6.25; 95% CI 2.53–15.47). Neither sex nor gestational age moderated associations between prenatal thyroid dysfunction and the majority of outcomes. School performance mediated 8% of the association between thyroid problems and SAD, 21% for CD and 53% for ODD.

vorige artikel The Work and Social Adjustment Scale, Youth and Parent Versions: Psychometric Evaluation of a Brief Measure of Functional Impairment in Young People

volgende artikel Attachment Facilitates Acculturative Learning and Adversity Moderates: Validating the Theory of Epistemic Trust in a Natural Experiment

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Titel: Psychiatric Disorders in the Adolescent Offspring of Mothers with Thyroid Problems During Pregnancy
Auteurs: Jacob Young
Calan Savoy
Ian Colman
Mark Ferro
Ryan J. Van Lieshout
Publicatiedatum: 01-02-2020
Uitgeverij: Springer US
Gepubliceerd in: Child Psychiatry & Human Development / Uitgave 3/2020
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI: https://doi.org/10.1007/s10578-020-00957-y

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Psychiatric Disorders in the Adolescent Offspring of Mothers with Thyroid Problems During Pregnancy

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