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Gepubliceerd in: Journal of Autism and Developmental Disorders 10/2020

24-02-2020 | Original Paper

Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort

Auteurs: Eric Fombonne, LeeAnne Green Snyder, Amy Daniels, Pamela Feliciano, Wendy Chung, The SPARK Consortium

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2020

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Abstract

This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK. Participants were 78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity.
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Literatuur
go back to reference American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: American Psychiatric Association.CrossRef American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: American Psychiatric Association.CrossRef
go back to reference Anderson, D. K., Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., et al. (2007). Patterns of growth in verbal abilities among children with autism spectrum disorder. Journal of Consulting and Clinical Psychology, 75(4), 594–604.PubMedCrossRef Anderson, D. K., Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., et al. (2007). Patterns of growth in verbal abilities among children with autism spectrum disorder. Journal of Consulting and Clinical Psychology, 75(4), 594–604.PubMedCrossRef
go back to reference Anderson, K. A., Roux, A. M., Kuo, A., & Shattuck, P. T. (2018). Social-ecological correlates in adult autism outcome studies: A scoping review. Pediatrics, 141(SuppI4), S306–S317.PubMedCrossRef Anderson, K. A., Roux, A. M., Kuo, A., & Shattuck, P. T. (2018). Social-ecological correlates in adult autism outcome studies: A scoping review. Pediatrics, 141(SuppI4), S306–S317.PubMedCrossRef
go back to reference Anderson, K. A., Shattuck, P. T., Cooper, B. P., Roux, A. M., & Wagner, M. (2014). Prevalence and correlates of postsecondary residential status among young adults with an autism spectrum disorder. Autism, 18(5), 562–570.PubMedCrossRef Anderson, K. A., Shattuck, P. T., Cooper, B. P., Roux, A. M., & Wagner, M. (2014). Prevalence and correlates of postsecondary residential status among young adults with an autism spectrum disorder. Autism, 18(5), 562–570.PubMedCrossRef
go back to reference Baio, J., Wiggins, L., Christensen, D. L., Maenner, M. J., Daniels, J., Warren, Z., et al. (2018). Prevalence of autism spectrum disorder among children aged 8 years—Autism and developmental disabilities monitoring network, 11 sites United States. MMWR Surveillance Summaries, 67(6), 1–23.PubMedCentralCrossRef Baio, J., Wiggins, L., Christensen, D. L., Maenner, M. J., Daniels, J., Warren, Z., et al. (2018). Prevalence of autism spectrum disorder among children aged 8 years—Autism and developmental disabilities monitoring network, 11 sites United States. MMWR Surveillance Summaries, 67(6), 1–23.PubMedCentralCrossRef
go back to reference Bal, V. H., Kim, S. H., Fok, M., & Lord, C. (2019). Autism spectrum disorder symptoms from ages 2 to 19 years: Implications for diagnosing adolescents and young adults. Autism Research, 1, 89–99.CrossRef Bal, V. H., Kim, S. H., Fok, M., & Lord, C. (2019). Autism spectrum disorder symptoms from ages 2 to 19 years: Implications for diagnosing adolescents and young adults. Autism Research, 1, 89–99.CrossRef
go back to reference Bolton, P. F., Carcani-Rathwell, I., Hutton, J., Goode, S., Howlin, P., & Rutter, M. (2011). Epilepsy in autism: Features and correlates. The British Journal of Psychiatry, 4, 289–294.CrossRef Bolton, P. F., Carcani-Rathwell, I., Hutton, J., Goode, S., Howlin, P., & Rutter, M. (2011). Epilepsy in autism: Features and correlates. The British Journal of Psychiatry, 4, 289–294.CrossRef
go back to reference Buck, T. R., Viskochil, J., Farley, M., Coon, H., McMahon, W. M., Morgan, J., et al. (2014). Psychiatric comorbidity and medication use in adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(12), 3063–3071.PubMedPubMedCentralCrossRef Buck, T. R., Viskochil, J., Farley, M., Coon, H., McMahon, W. M., Morgan, J., et al. (2014). Psychiatric comorbidity and medication use in adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(12), 3063–3071.PubMedPubMedCentralCrossRef
go back to reference Cashin, A., Buckley, T., Trollor, J. N., & Lennox, N. (2018). A scoping review of what is known of the physical health of adults with autism spectrum disorder. Journal of Intellectual Disabilities, 1, 96–108.CrossRef Cashin, A., Buckley, T., Trollor, J. N., & Lennox, N. (2018). A scoping review of what is known of the physical health of adults with autism spectrum disorder. Journal of Intellectual Disabilities, 1, 96–108.CrossRef
go back to reference Cassidy, S., Bradley, P., Robinson, J., Allison, C., McHugh, M., & Baron-Cohen, S. (2014). Suicidal ideation and suicide plans or attempts in adults with Asperger's syndrome attending a specialist diagnostic clinic: A clinical cohort study. The Lancet Psychiatry, 1(2), 142–147.PubMedCrossRef Cassidy, S., Bradley, P., Robinson, J., Allison, C., McHugh, M., & Baron-Cohen, S. (2014). Suicidal ideation and suicide plans or attempts in adults with Asperger's syndrome attending a specialist diagnostic clinic: A clinical cohort study. The Lancet Psychiatry, 1(2), 142–147.PubMedCrossRef
go back to reference Cassidy, S. A., Bradley, L., Bowen, E., Wigham, S., & Rodgers, J. (2018). Measurement properties of tools used to assess suicidality in autistic and general population adults: A systematic review. Clinical Psychology Review, 62, 56–70.PubMedCrossRef Cassidy, S. A., Bradley, L., Bowen, E., Wigham, S., & Rodgers, J. (2018). Measurement properties of tools used to assess suicidality in autistic and general population adults: A systematic review. Clinical Psychology Review, 62, 56–70.PubMedCrossRef
go back to reference Cervantes, P. E., & Matson, J. L. (2015). Comorbid symptomology in adults with autism spectrum disorder and intellectual disability. Journal of Autism and Developmental Disorders, 45(12), 3961–3970.PubMedCrossRef Cervantes, P. E., & Matson, J. L. (2015). Comorbid symptomology in adults with autism spectrum disorder and intellectual disability. Journal of Autism and Developmental Disorders, 45(12), 3961–3970.PubMedCrossRef
go back to reference Charlson, F. J., Ferrari, A. J., Santomauro, D. F., Diminic, S., Stockings, E., Scott, J. G., et al. (2018). Global epidemiology and burden of schizophrenia: Findings from the global burden of disease study 2016. Schizophrenia Bulletin: A Journal of Psychoses and Related Disorders, 44(6), 1195–1203.CrossRef Charlson, F. J., Ferrari, A. J., Santomauro, D. F., Diminic, S., Stockings, E., Scott, J. G., et al. (2018). Global epidemiology and burden of schizophrenia: Findings from the global burden of disease study 2016. Schizophrenia Bulletin: A Journal of Psychoses and Related Disorders, 44(6), 1195–1203.CrossRef
go back to reference Chisholm, K., Lin, A., Abu-Akel, A., & Wood, S. J. (2015). The association between autism and schizophrenia spectrum disorders: A review of eight alternate models of co-occurrence. Neuroscience Biobehavioral Reviews, 55, 173–183.PubMedCrossRef Chisholm, K., Lin, A., Abu-Akel, A., & Wood, S. J. (2015). The association between autism and schizophrenia spectrum disorders: A review of eight alternate models of co-occurrence. Neuroscience Biobehavioral Reviews, 55, 173–183.PubMedCrossRef
go back to reference Cooper, S. A., Smiley, E., Morrison, J., Williamson, A., & Allan, L. (2007). Mental ill-health in adults with intellectual disabilities: Prevalence and associated factors. The British Journal of Psychiatry, 190, 27–35.PubMedCrossRef Cooper, S. A., Smiley, E., Morrison, J., Williamson, A., & Allan, L. (2007). Mental ill-health in adults with intellectual disabilities: Prevalence and associated factors. The British Journal of Psychiatry, 190, 27–35.PubMedCrossRef
go back to reference Croen, L. A., Zerbo, O., Qian, Y., Massolo, M. L., Rich, S., Sidney, S., et al. (2015). The health status of adults on the autism spectrum. Autism, 19(7), 814–823.PubMedCrossRef Croen, L. A., Zerbo, O., Qian, Y., Massolo, M. L., Rich, S., Sidney, S., et al. (2015). The health status of adults on the autism spectrum. Autism, 19(7), 814–823.PubMedCrossRef
go back to reference Cross-Disorder Group of the Psychiatric Genomics Consortium. (2013). Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis. The Lancet, 381(9875), 1371–1379.CrossRef Cross-Disorder Group of the Psychiatric Genomics Consortium. (2013). Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis. The Lancet, 381(9875), 1371–1379.CrossRef
go back to reference Daniels, A. M., Rosenberg, R. E., Anderson, C., Law, J. K., Marvin, A. R., & Law, P. A. (2012). Verification of parent-report of child autism spectrum disorder diagnosis to a web-based autism registry. Journal of Autism and Developmental Disorders, 42(2), 257–265.PubMedCrossRef Daniels, A. M., Rosenberg, R. E., Anderson, C., Law, J. K., Marvin, A. R., & Law, P. A. (2012). Verification of parent-report of child autism spectrum disorder diagnosis to a web-based autism registry. Journal of Autism and Developmental Disorders, 42(2), 257–265.PubMedCrossRef
go back to reference Davignon, M. N., Qian, Y., Massolo, M., & Croen, L. A. (2018). Psychiatric and medical conditions in transition-aged individuals with ASD. Pediatrics, 141(Suppl 4), 5335–5345. Davignon, M. N., Qian, Y., Massolo, M., & Croen, L. A. (2018). Psychiatric and medical conditions in transition-aged individuals with ASD. Pediatrics, 141(Suppl 4), 5335–5345.
go back to reference Farley, M. A., McMahon, W. M., Fombonne, E., Jenson, W. R., Miller, J., Gardner, M., et al. (2009). Twenty-year outcome for individuals with autism and average or near-average cognitive abilities. Autism Research, 2(2), 109–118.PubMedCrossRef Farley, M. A., McMahon, W. M., Fombonne, E., Jenson, W. R., Miller, J., Gardner, M., et al. (2009). Twenty-year outcome for individuals with autism and average or near-average cognitive abilities. Autism Research, 2(2), 109–118.PubMedCrossRef
go back to reference Feliciano, P., Zhou, X., Astrovskaya, I., Turner, T. N., Wang, T., Brueggeman, L., et al. (2019). Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. NPJ Genomic Medicine, 4, 19.PubMedPubMedCentralCrossRef Feliciano, P., Zhou, X., Astrovskaya, I., Turner, T. N., Wang, T., Brueggeman, L., et al. (2019). Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. NPJ Genomic Medicine, 4, 19.PubMedPubMedCentralCrossRef
go back to reference Fombonne, E., Du Mazaubrun, C., Cans, C., & Grandjean, H. (1997). Autism and associated medical disorders in a French epidemiological survey. Journal of the American Academy of Child & Adolescent Psychiatry, 36(11), 1561–1569. Fombonne, E., Du Mazaubrun, C., Cans, C., & Grandjean, H. (1997). Autism and associated medical disorders in a French epidemiological survey. Journal of the American Academy of Child & Adolescent Psychiatry, 36(11), 1561–1569.
go back to reference Fombonne, E., Rogé, B., Claverie, J., Courty, S., & Frémolle, J. (1999). Microcephaly and macrocephaly in autism. Journal of Autism and Developmental Disorders, 29(2), 113–119.PubMedCrossRef Fombonne, E., Rogé, B., Claverie, J., Courty, S., & Frémolle, J. (1999). Microcephaly and macrocephaly in autism. Journal of Autism and Developmental Disorders, 29(2), 113–119.PubMedCrossRef
go back to reference Flynn, S., Vereenooghe, L., Hastings, R. P., Adams, D., Cooper, S. A., Gore, N., et al. (2017). Measurement tools for mental health problems and mental well-being in people with severe or profound intellectual disabilities: A systematic review. Clinical Psychology Review, 57, 32–44.PubMedCrossRef Flynn, S., Vereenooghe, L., Hastings, R. P., Adams, D., Cooper, S. A., Gore, N., et al. (2017). Measurement tools for mental health problems and mental well-being in people with severe or profound intellectual disabilities: A systematic review. Clinical Psychology Review, 57, 32–44.PubMedCrossRef
go back to reference Green, L., McNeil, K., Korossy, M., Boyd, K., Grier, E., Ketchell, M., et al. (2018). HELP for behaviours that challenge in adults with intellectual and developmental disabilities. Canadian Family Physician, 64(Suppl 2), S23–S31.PubMedPubMedCentral Green, L., McNeil, K., Korossy, M., Boyd, K., Grier, E., Ketchell, M., et al. (2018). HELP for behaviours that challenge in adults with intellectual and developmental disabilities. Canadian Family Physician, 64(Suppl 2), S23–S31.PubMedPubMedCentral
go back to reference Howlin, P., & Magiati, I. (2017). Autism spectrum disorder: Outcomes in adulthood. Current Opinion in Psychiatry, 30(2), 69–76.PubMedCrossRef Howlin, P., & Magiati, I. (2017). Autism spectrum disorder: Outcomes in adulthood. Current Opinion in Psychiatry, 30(2), 69–76.PubMedCrossRef
go back to reference Howlin, P., Moss, P., Savage, S., & Rutter, M. (2013). Social outcomes in mid-to later adulthood among individuals diagnosed with autism and average nonverbal IQ as children. Journal of the American Academy of Child & Adolescent Psychiatry, 52(6), 572–581.CrossRef Howlin, P., Moss, P., Savage, S., & Rutter, M. (2013). Social outcomes in mid-to later adulthood among individuals diagnosed with autism and average nonverbal IQ as children. Journal of the American Academy of Child & Adolescent Psychiatry, 52(6), 572–581.CrossRef
go back to reference Howlin, P., Savage, S., Moss, P., Tempier, A., & Rutter, M. (2014). Cognitive and language skills in adults with autism: A 40-year follow-up. The Journal of Child Psychology and Psychiatry, 55(1), 49–58.PubMedCrossRef Howlin, P., Savage, S., Moss, P., Tempier, A., & Rutter, M. (2014). Cognitive and language skills in adults with autism: A 40-year follow-up. The Journal of Child Psychology and Psychiatry, 55(1), 49–58.PubMedCrossRef
go back to reference Howlin, P., & Taylor, J. L. (2015). Addressing the need for high quality research on autism in adulthood. Autism, 19(7), 771–773.PubMedCrossRef Howlin, P., & Taylor, J. L. (2015). Addressing the need for high quality research on autism in adulthood. Autism, 19(7), 771–773.PubMedCrossRef
go back to reference Jacob, A., Scott, M., Falkmer, M., & Falkmer, T. (2015). The costs and benefits of employing an adult with autism spectrum disorder: A systematic review. PLoS ONE, 10(10), e0139896.PubMedPubMedCentralCrossRef Jacob, A., Scott, M., Falkmer, M., & Falkmer, T. (2015). The costs and benefits of employing an adult with autism spectrum disorder: A systematic review. PLoS ONE, 10(10), e0139896.PubMedPubMedCentralCrossRef
go back to reference Jokiranta, E., Brown, A. S., Heinimaa, M., Cheslack-Postava, K., Suominen, A., & Sourander, A. (2013). Parental psychiatric disorders and autism spectrum disorders. Psychiatry Research, 207(3), 203–211.PubMedPubMedCentralCrossRef Jokiranta, E., Brown, A. S., Heinimaa, M., Cheslack-Postava, K., Suominen, A., & Sourander, A. (2013). Parental psychiatric disorders and autism spectrum disorders. Psychiatry Research, 207(3), 203–211.PubMedPubMedCentralCrossRef
go back to reference Jones, K. B., Cottle, K., Bakian, A., Farley, M., Bilder, D., Coon, H., et al. (1980s). A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study. Autism, 20(5), 551–561.PubMedCrossRef Jones, K. B., Cottle, K., Bakian, A., Farley, M., Bilder, D., Coon, H., et al. (1980s). A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study. Autism, 20(5), 551–561.PubMedCrossRef
go back to reference Kasari, C., Brady, N., Lord, C., & Tager-Flusberg, H. (2013). Assessing the minimally verbal school-aged child with autism spectrum disorder. Autism Research, 6(6), 479–493.PubMedPubMedCentralCrossRef Kasari, C., Brady, N., Lord, C., & Tager-Flusberg, H. (2013). Assessing the minimally verbal school-aged child with autism spectrum disorder. Autism Research, 6(6), 479–493.PubMedPubMedCentralCrossRef
go back to reference Kendler, K. S., Gallagher, T. J., Abelson, J. M., & Kessler, R. C. (1996). Lifetime prevalence, demographic risk factors, and diagnostic validity of nonaffective psychosis as assessed in a US community sample. The National Comorbidity Survey. Archives of General Psychiatry, 53(11), 1022–1031.PubMedCrossRef Kendler, K. S., Gallagher, T. J., Abelson, J. M., & Kessler, R. C. (1996). Lifetime prevalence, demographic risk factors, and diagnostic validity of nonaffective psychosis as assessed in a US community sample. The National Comorbidity Survey. Archives of General Psychiatry, 53(11), 1022–1031.PubMedCrossRef
go back to reference Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62(6), 593–602.PubMedCrossRef Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62(6), 593–602.PubMedCrossRef
go back to reference King, B. H., & Lord, C. (2011). Is schizophrenia on the autism spectrum? Brain Research, 1380, 34–41.PubMedCrossRef King, B. H., & Lord, C. (2011). Is schizophrenia on the autism spectrum? Brain Research, 1380, 34–41.PubMedCrossRef
go back to reference Kogan, M. D., Vladutiu, C. J., Schieve, L. A., Ghandour, R. M., Blumberg, S. J., Zablotsky, B., et al. (2018). The prevalence of parent-reported autism spectrum disorder among US children. Pediatrics, 142(6), e20174161.PubMedCrossRef Kogan, M. D., Vladutiu, C. J., Schieve, L. A., Ghandour, R. M., Blumberg, S. J., Zablotsky, B., et al. (2018). The prevalence of parent-reported autism spectrum disorder among US children. Pediatrics, 142(6), e20174161.PubMedCrossRef
go back to reference Kohane, I. S., McMurry, A., Weber, G., MacFadden, D., Rappaport, L., Kunkel, L., et al. (2012). The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS ONE, 7(4), e33224.PubMedPubMedCentralCrossRef Kohane, I. S., McMurry, A., Weber, G., MacFadden, D., Rappaport, L., Kunkel, L., et al. (2012). The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS ONE, 7(4), e33224.PubMedPubMedCentralCrossRef
go back to reference Larson, F. V., Wagner, A. P., Jones, P. B., Tantam, D., Lai, M. C., Baron-Cohen, S., et al. (2017). Psychosis in autism: comparison of the features of both conditions in a dually affected cohort. The British Journal of Psychiatry, 210(4), 269–275.PubMedPubMedCentralCrossRef Larson, F. V., Wagner, A. P., Jones, P. B., Tantam, D., Lai, M. C., Baron-Cohen, S., et al. (2017). Psychosis in autism: comparison of the features of both conditions in a dually affected cohort. The British Journal of Psychiatry, 210(4), 269–275.PubMedPubMedCentralCrossRef
go back to reference Lee, H., Marvin, A. R., Watson, T., Piggot, J., Law, J. K., Law, P. A., et al. (2010). Accuracy of phenotyping of autistic children based on Internet implemented parent report. American Journal of Medical Genetics Part B Neuropsychiatric Genetics, 153B(6), 1119–1126. Lee, H., Marvin, A. R., Watson, T., Piggot, J., Law, J. K., Law, P. A., et al. (2010). Accuracy of phenotyping of autistic children based on Internet implemented parent report. American Journal of Medical Genetics Part B Neuropsychiatric Genetics, 153B(6), 1119–1126.
go back to reference Lever, A. G., & Geurts, H. M. (2016). Psychiatric co-occurring symptoms and disorders in young, middle-aged, and older adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 46(6), 1916–1930.PubMedPubMedCentralCrossRef Lever, A. G., & Geurts, H. M. (2016). Psychiatric co-occurring symptoms and disorders in young, middle-aged, and older adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 46(6), 1916–1930.PubMedPubMedCentralCrossRef
go back to reference Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36(7), 849–861.CrossRefPubMed Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36(7), 849–861.CrossRefPubMed
go back to reference Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. The Lancet, 392(10146), 508–520.CrossRef Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. The Lancet, 392(10146), 508–520.CrossRef
go back to reference Magiati, I., Tay, X. W., & Howlin, P. (2014). Cognitive, language, social and behavioural outcomes in adults with autism spectrum disorders: A systematic review of longitudinal follow-up studies in adulthood. Clinical Psychology Review, 34(1), 73–86.PubMedCrossRef Magiati, I., Tay, X. W., & Howlin, P. (2014). Cognitive, language, social and behavioural outcomes in adults with autism spectrum disorders: A systematic review of longitudinal follow-up studies in adulthood. Clinical Psychology Review, 34(1), 73–86.PubMedCrossRef
go back to reference Marsack-Topolewski, C. N., & Church, H. L. (2019). Impact of caregiver burden on quality of life for parents of adult children with autism spectrum disorder. American Journal on Intellectual and Developmental Disabilities, 124(2), 145–156.PubMedCrossRef Marsack-Topolewski, C. N., & Church, H. L. (2019). Impact of caregiver burden on quality of life for parents of adult children with autism spectrum disorder. American Journal on Intellectual and Developmental Disabilities, 124(2), 145–156.PubMedCrossRef
go back to reference Merikangas, K. R., Jin, R., He, J. P., Kessler, R. C., Lee, S., Sampson, N. A., et al. (2011). Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Archives of General Psychiatry, 68(3), 241–251.PubMedPubMedCentralCrossRef Merikangas, K. R., Jin, R., He, J. P., Kessler, R. C., Lee, S., Sampson, N. A., et al. (2011). Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Archives of General Psychiatry, 68(3), 241–251.PubMedPubMedCentralCrossRef
go back to reference Myers, S. M., Voight, R. G., Colligan, R. C., Weaver, A. L., Storlie, C. B., Stoeckel, R. E., et al. (2019). Autism spectrum disorder: Incidence and time trends over two decades in a population-based birth cohort. Journal of Autism and Developmental Disorders, 49(4), 1455–1474.PubMedPubMedCentralCrossRef Myers, S. M., Voight, R. G., Colligan, R. C., Weaver, A. L., Storlie, C. B., Stoeckel, R. E., et al. (2019). Autism spectrum disorder: Incidence and time trends over two decades in a population-based birth cohort. Journal of Autism and Developmental Disorders, 49(4), 1455–1474.PubMedPubMedCentralCrossRef
go back to reference Nathenson, R. A., & Zablotsky, B. (2017). The transition to the adult health care system among youths with autism spectrum disorder. Psychiatric Services, 68(7), 735–738.PubMedCrossRef Nathenson, R. A., & Zablotsky, B. (2017). The transition to the adult health care system among youths with autism spectrum disorder. Psychiatric Services, 68(7), 735–738.PubMedCrossRef
go back to reference Nicholas, D. B., Hodgetts, S., Zwaigenbaum, L., Smith, L. E., Shattuck, P., Parr, J. R., et al. (2017). Research needs and priorities for transition and employment in autism: Considerations reflected in a "Special Interest Group" at the International Meeting for Autism Research. Autism Research, 10(1), 15–24.PubMedCrossRef Nicholas, D. B., Hodgetts, S., Zwaigenbaum, L., Smith, L. E., Shattuck, P., Parr, J. R., et al. (2017). Research needs and priorities for transition and employment in autism: Considerations reflected in a "Special Interest Group" at the International Meeting for Autism Research. Autism Research, 10(1), 15–24.PubMedCrossRef
go back to reference Nicolaidis, C., Raymaker, D. M., Ashkenazy, E., McDonald, K. E., Dern, S., Baggs, A. E., et al. (2015). "Respect the way I need to communicate with you": Healthcare experiences of adults on the autism spectrum. Autism, 19(7), 824–831.PubMedPubMedCentralCrossRef Nicolaidis, C., Raymaker, D. M., Ashkenazy, E., McDonald, K. E., Dern, S., Baggs, A. E., et al. (2015). "Respect the way I need to communicate with you": Healthcare experiences of adults on the autism spectrum. Autism, 19(7), 824–831.PubMedPubMedCentralCrossRef
go back to reference Norrelgen, F., Fernell, E., Eriksson, M., Hedvall, Å., Persson, C., Sjölin, M., et al. (2015). Children with autism spectrum disorders who do not develop phrase speech in the preschool years. Autism, 19(8), 934–943.PubMedCrossRef Norrelgen, F., Fernell, E., Eriksson, M., Hedvall, Å., Persson, C., Sjölin, M., et al. (2015). Children with autism spectrum disorders who do not develop phrase speech in the preschool years. Autism, 19(8), 934–943.PubMedCrossRef
go back to reference Nylander, L., Axmon, A., Björne, P., Ahlström, G., & Gillberg, C. (2018). Older adults with autism spectrum disorders in Sweden: A register study of diagnoses, psychiatric care utilization and psychotropic medication of 601 individuals. Journal of Autism and Developmental Disorders, 48(9), 3076–3085.PubMedPubMedCentralCrossRef Nylander, L., Axmon, A., Björne, P., Ahlström, G., & Gillberg, C. (2018). Older adults with autism spectrum disorders in Sweden: A register study of diagnoses, psychiatric care utilization and psychotropic medication of 601 individuals. Journal of Autism and Developmental Disorders, 48(9), 3076–3085.PubMedPubMedCentralCrossRef
go back to reference Phillips, K. L., Schieve, L. A., Visser, S., Boulet, S., Sharma, A. J., Kogan, M. D., et al. (2014). Prevalence and impact of unhealthy weight in a national sample of US adolescents with autism and other learning and behavioral disabilities. Maternal and Child Health Journal, 18(8), 1964–1975.PubMedPubMedCentralCrossRef Phillips, K. L., Schieve, L. A., Visser, S., Boulet, S., Sharma, A. J., Kogan, M. D., et al. (2014). Prevalence and impact of unhealthy weight in a national sample of US adolescents with autism and other learning and behavioral disabilities. Maternal and Child Health Journal, 18(8), 1964–1975.PubMedPubMedCentralCrossRef
go back to reference Piven, J., Rabins, P., Autism-in-Older Adults Working Group, et al. (2011). Autism spectrum disorders in older adults: Toward defining a research agenda. Journal of the American Geriatrics Society, 59(11), 2151–2155.PubMedCrossRef Piven, J., Rabins, P., Autism-in-Older Adults Working Group, et al. (2011). Autism spectrum disorders in older adults: Toward defining a research agenda. Journal of the American Geriatrics Society, 59(11), 2151–2155.PubMedCrossRef
go back to reference Purisch, S. E., & Gyamfi-Bannerman, C. (2017). Epidemiology of preterm birth. Seminars in Perinatology, 41(7), 387–391.PubMedCrossRef Purisch, S. E., & Gyamfi-Bannerman, C. (2017). Epidemiology of preterm birth. Seminars in Perinatology, 41(7), 387–391.PubMedCrossRef
go back to reference Rai, D., Heuvelman, H., Dalman, C., Culpin, I., Lundberg, M., Carpenter, P., et al. (2018). Association between autism spectrum disorders with or without intellectual disability and depression in young adulthood. JAMA Network Open, 4, e181465.CrossRef Rai, D., Heuvelman, H., Dalman, C., Culpin, I., Lundberg, M., Carpenter, P., et al. (2018). Association between autism spectrum disorders with or without intellectual disability and depression in young adulthood. JAMA Network Open, 4, e181465.CrossRef
go back to reference Rattaz, C., Michelon, C., Roeyers, H., & Baghdadli, A. (2017). Quality of life in parents of young adults with ASD: EpiTED cohort. Journal of Autism and Developmental Disorders, 47(9), 2826–2837.PubMedCrossRef Rattaz, C., Michelon, C., Roeyers, H., & Baghdadli, A. (2017). Quality of life in parents of young adults with ASD: EpiTED cohort. Journal of Autism and Developmental Disorders, 47(9), 2826–2837.PubMedCrossRef
go back to reference Robison, J. E. (2019). Autism prevalence and outcomes in older adults. Autism Research, 12(3), 370–374.PubMedCrossRef Robison, J. E. (2019). Autism prevalence and outcomes in older adults. Autism Research, 12(3), 370–374.PubMedCrossRef
go back to reference Rosen, T. E., Mazefsky, C. A., Vasa, R. A., & Lerner, M. D. (2018). Co-occurring psychiatric conditions in autism spectrum disorder. International Review of Psychiatry, 30(1), 40–61.CrossRefPubMed Rosen, T. E., Mazefsky, C. A., Vasa, R. A., & Lerner, M. D. (2018). Co-occurring psychiatric conditions in autism spectrum disorder. International Review of Psychiatry, 30(1), 40–61.CrossRefPubMed
go back to reference Roux, A. M., Shattuck, P. T., Cooper, B. P., Anderson, K. A., Wagner, M., & Narendorf, S. C. (2013). Postsecondary employment experiences among young adults with an autism spectrum disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 52(9), 931–939.CrossRef Roux, A. M., Shattuck, P. T., Cooper, B. P., Anderson, K. A., Wagner, M., & Narendorf, S. C. (2013). Postsecondary employment experiences among young adults with an autism spectrum disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 52(9), 931–939.CrossRef
go back to reference Shattuck, P. T., Wagner, M., Narendorf, S., Sterzing, P., & Hensley, M. (2011). Post-high school service use among young adults with an autism spectrum disorder. Archives of Pediatrics and Adolescent Medicine, 165(2), 141–146.PubMedCrossRef Shattuck, P. T., Wagner, M., Narendorf, S., Sterzing, P., & Hensley, M. (2011). Post-high school service use among young adults with an autism spectrum disorder. Archives of Pediatrics and Adolescent Medicine, 165(2), 141–146.PubMedCrossRef
go back to reference Shattuck, P. T., Narendorf, S. C., Cooper, B., Sterzing, P. R., Wagner, M., & Taylor, J. L. (2012). Postsecondary education and employment among youth with an autism spectrum disorder. Pediatrics, 129(6), 1042–1049.PubMedPubMedCentralCrossRef Shattuck, P. T., Narendorf, S. C., Cooper, B., Sterzing, P. R., Wagner, M., & Taylor, J. L. (2012). Postsecondary education and employment among youth with an autism spectrum disorder. Pediatrics, 129(6), 1042–1049.PubMedPubMedCentralCrossRef
go back to reference Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921–929.CrossRef Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921–929.CrossRef
go back to reference Skokauskas, N., & Frodl, T. (2015). Overlap between autism spectrum disorder and bipolar affective disorder. Psychopathology, 48(4), 209–216.PubMedCrossRef Skokauskas, N., & Frodl, T. (2015). Overlap between autism spectrum disorder and bipolar affective disorder. Psychopathology, 48(4), 209–216.PubMedCrossRef
go back to reference Smiley, E. (2005). Epidemiology of mental health problems in adults with learning disability: An update. Advances in Psychiatric Treatment, 11(3), 214–222.CrossRef Smiley, E. (2005). Epidemiology of mental health problems in adults with learning disability: An update. Advances in Psychiatric Treatment, 11(3), 214–222.CrossRef
go back to reference Supekar, K., Iyer, T., & Menon, V. (2017). The influence of sex and age on prevalence rates of comorbid conditions in autism. Autism Research, 10(5), 778–789.PubMedCrossRef Supekar, K., Iyer, T., & Menon, V. (2017). The influence of sex and age on prevalence rates of comorbid conditions in autism. Autism Research, 10(5), 778–789.PubMedCrossRef
go back to reference St Louis, A. M., Kim, K., Browne, M. L., Liu, G., Liberman, R. F., Nembhard, W. N., et al. (2017). Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007. Birth Defects Research, 109(18), 1442–1450.PubMedCrossRef St Louis, A. M., Kim, K., Browne, M. L., Liu, G., Liberman, R. F., Nembhard, W. N., et al. (2017). Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007. Birth Defects Research, 109(18), 1442–1450.PubMedCrossRef
go back to reference Tager-Flusberg, H., & Kasari, C. (2013). Minimally verbal school-aged children with autism spectrum disorder: The neglected end of the spectrum. Autism Research, 6(6), 468–478.PubMedCrossRef Tager-Flusberg, H., & Kasari, C. (2013). Minimally verbal school-aged children with autism spectrum disorder: The neglected end of the spectrum. Autism Research, 6(6), 468–478.PubMedCrossRef
go back to reference Tyler, C. V., Schramm, S. C., Karafa, M., Tang, A. S., & Jain, A. K. (2011). Chronic disease risks in young adults with autism spectrum disorder: Forewarned is forearmed. American Journal on Intellectual and Developmental Disabilities, 116(5), 371–380.PubMedCrossRef Tyler, C. V., Schramm, S. C., Karafa, M., Tang, A. S., & Jain, A. K. (2011). Chronic disease risks in young adults with autism spectrum disorder: Forewarned is forearmed. American Journal on Intellectual and Developmental Disabilities, 116(5), 371–380.PubMedCrossRef
go back to reference Underwood, J. F. G., Kendall, K. M., Lewis, C., Anney, R., van den Bree, M. B. M., et al. (2019). Autism spectrum disorder diagnosis in adults: Phenotype and genotype findings from a clinically derived cohort. The British Journal of Psychiatry, 26, 1–7. Underwood, J. F. G., Kendall, K. M., Lewis, C., Anney, R., van den Bree, M. B. M., et al. (2019). Autism spectrum disorder diagnosis in adults: Phenotype and genotype findings from a clinically derived cohort. The British Journal of Psychiatry, 26, 1–7.
go back to reference Wang, W., Liu, J., Shi, S., Liu, T., Ma, L., Ma, X., et al. (2018). Altered resting-state functional activity in patients with autism spectrum disorder: A quantitative meta-analysis. Frontiers in Neurology, 9, 556.PubMedPubMedCentralCrossRef Wang, W., Liu, J., Shi, S., Liu, T., Ma, L., Ma, X., et al. (2018). Altered resting-state functional activity in patients with autism spectrum disorder: A quantitative meta-analysis. Frontiers in Neurology, 9, 556.PubMedPubMedCentralCrossRef
go back to reference Warner, G., Parr, J. R., & Cusack, J. (2019). Workshop report: Establishing priority research areas to improve the physical health and well-being of autistic adults and older people. Autism in Adulthood, 1(1), 20–26.CrossRef Warner, G., Parr, J. R., & Cusack, J. (2019). Workshop report: Establishing priority research areas to improve the physical health and well-being of autistic adults and older people. Autism in Adulthood, 1(1), 20–26.CrossRef
go back to reference Weiss, J. A., Isaacs, B., Diepstra, H., Wilton, A. S., Brown, H. K., McGarry, C., et al. (2018). Health concerns and health service utilization in a population cohort of young adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 48(1), 36–44.PubMedCrossRef Weiss, J. A., Isaacs, B., Diepstra, H., Wilton, A. S., Brown, H. K., McGarry, C., et al. (2018). Health concerns and health service utilization in a population cohort of young adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 48(1), 36–44.PubMedCrossRef
go back to reference Yorke, I., White, P., Weston, A., Rafla, M., Charman, T., & Simonoff, E. (2018). The association between emotional and behavioral problems in children with autism spectrum disorder and psychological distress in their parents: A systematic review and meta-analysis. Journal of Autism and Developmental Disorders, 48(10), 3393–3415.PubMedPubMedCentralCrossRef Yorke, I., White, P., Weston, A., Rafla, M., Charman, T., & Simonoff, E. (2018). The association between emotional and behavioral problems in children with autism spectrum disorder and psychological distress in their parents: A systematic review and meta-analysis. Journal of Autism and Developmental Disorders, 48(10), 3393–3415.PubMedPubMedCentralCrossRef
Metagegevens
Titel
Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort
Auteurs
Eric Fombonne
LeeAnne Green Snyder
Amy Daniels
Pamela Feliciano
Wendy Chung
The SPARK Consortium
Publicatiedatum
24-02-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04414-6

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