Abstract
Poor cell culture practice leads to poor science due largely to issues of cross-contamination between cell lines and of microbial contamination, but can be avoided by careful quality control and good laboratory practice. This chapter provides a brief and practical outline of the steps needed to mitigate the risks associated with poor cell culture practice. Good Laboratory Practice (GLP) is a set of principles that provides a framework within which laboratory studies are planned, performed, monitored, recorded, reported, and archived to ensure the reliability of data generated within a compliant laboratory. A key feature of this is the generation of quality-control methods and data management within the cell culture laboratory.
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© 2011 Springer Science+Business Media, LLC
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Knight, L.A., Cree, I.A. (2011). Quality Assurance and Good Laboratory Practice. In: Cree, I. (eds) Cancer Cell Culture. Methods in Molecular Biology, vol 731. Humana Press. https://doi.org/10.1007/978-1-61779-080-5_10
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DOI: https://doi.org/10.1007/978-1-61779-080-5_10
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Publisher Name: Humana Press
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Online ISBN: 978-1-61779-080-5
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