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01-04-2010 | Original Article

Prefrontal Dysfunction in Attention-Deficit/Hyperactivity Disorder as Measured by Near-Infrared Spectroscopy

Auteurs: Hideki Negoro, Masayuki Sawada, Junzo Iida, Toyosaku Ota, Shohei Tanaka, Toshifumi Kishimoto

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 2/2010

Abstract

Recent developments in near-infrared spectroscopy (NIRS) have enabled non-invasive clarification of brain functions in psychiatric disorders with measurement of hemoglobin concentrations as cerebral blood volume. Twenty medication-naïve children with attention-deficit/hyperactivity disorder (ADHD) and 20 age- and sex-matched healthy control subjects participated in the present study after giving consent. The relative concentrations of oxyhemoglobin (oxy-Hb) were measured with frontal probes every 0.1 s during the Stroop color-word task, using 24-channel NIRS machines. During the Stroop color-word task, the oxy-Hb changes in the control group were significantly larger than that in the ADHD group in the inferior prefrontal cortex, especially in the inferior lateral prefrontal cortex bilaterally. The Stroop color-word task used with NIRS may be one useful measurement to assess prefrontal brain dysfunction in ADHD children.

vorige artikel A Systematic Review of Parenting in Relation to the Development of Comorbidities and Functional Impairments in Children with Attention-Deficit/Hyperactivity Disorder (ADHD)

volgende artikel “You Might Belong in Gryffindor”: Children’s Courage and Its Relationships to Anxiety Symptoms, Big Five Personality Traits, and Sex Roles

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Titel: Prefrontal Dysfunction in Attention-Deficit/Hyperactivity Disorder as Measured by Near-Infrared Spectroscopy
Auteurs: Hideki Negoro
Masayuki Sawada
Junzo Iida
Toyosaku Ota
Shohei Tanaka
Toshifumi Kishimoto
Publicatiedatum: 01-04-2010
Uitgeverij: Springer US
Gepubliceerd in: Child Psychiatry & Human Development / Uitgave 2/2010
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI: https://doi.org/10.1007/s10578-009-0160-y

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