Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-10-2008 | Original Paper

Predictors of Psychiatric Symptoms in Children with an Autism Spectrum Disorder

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2008

Abstract

This study examined mental health risk/protective factors for DSM-IV psychiatric symptoms in children with an autism spectrum disorder (ASD) and their contribution to functioning separate from ASD symptom severity. Mothers/teachers completed measures of risk/protection and social, adaptive, and school functioning in 6- to 12-year-olds with a diagnosed ASD (N = 238). Bivariate correlations and simultaneous regression analyses indicated a unique pattern of predictors for attention-deficit/hyperactivity disorder, aggression, anxiety, and depression symptoms. Moreover, psychiatric symptoms differentially predicted social and school performance. Findings indicate that co-occurring psychiatric symptoms and their associated mental health risk/protective factors may have important clinical implications and generally support a biopsychosocial model of psychopathology in children with an ASD that appears to share many similarities with models for nonASD children.

vorige artikel Social Anxiety in High-functioning Children and Adolescents with Autism and Asperger Syndrome

volgende artikel When Prototypes Are Not Best: Judgments Made by Children with Autism

Achenbach, T. M. (1991a). Manual for the Child Behavior Checklist/4–18 and 1991 profile. Burlington, VT: University of Vermont Department of Psychiatry.

Achenbach, T. M. (1991b). Manual for the teacher’s report form and 1991 profile. Burlington, VT: University of Vermont Department of Psychiatry.

Achenbach, T. M., McConaughy, S. H., & Howell, C. T. (1987). Child/adolescent behavioral and emotional problems: Implications of cross-informant correlations for situational specificity. Psychological Bulletin, 101, 213–232.PubMedCrossRef

Allen, N. B., Lewinsohn, P. M., & Seeley, J. R. (1998). Prenatal and perinatal influences on risk for psychopathology in childhood and adolescence. Development and Psychopathology, 10, 513–529.PubMedCrossRef

American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders, 4th ed. (DSM-IV). Washington, DC: American Psychiatric Association.

Badcock, C., & Crespi, B. (2006). Imbalanced genomic imprinting in brain development: An evolutional basis for the aetiology of autism. Journal of Evolutionary Biology, 19, 1007–1032.PubMedCrossRef

Baillargeon, R. H., Boulerice, B., Tremblay, R. E., Zoccolillo, M., Vitaro, F., & Kohen, D. E. (2001). Modeling interinformant agreement in the absence of a “gold standard”. Journal of Child Psychology and Psychiatry, 42, 463–473. PubMedCrossRef

Bauminger, N., & Kasari, C. (2000). Loneliness and friendship in high-functioning children with autism. Child Development, 71, 447–456.PubMedCrossRef

Bauminger, N., Shulman, C., & Agam, G. (2003). Peer interactions and loneliness in high-functioning children with autism. Journal of Autism and Developmental Disorders, 33, 489–507.PubMedCrossRef

Biederman, J., Faraone, S., Milberger, S., Curtis, S., Chen, L., Marrs, A., Ouellete, C., Moore, P., & Spencer, T. (1996). Predictors of persistence and remission of ADHD into adolescence: Results from a four-year prospective follow-up study. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 343–351.PubMedCrossRef

Cohen, P., Velez, C. N., Brook, J., & Smith, J. (1989). Mechanisms of the relation between perinatal problems, early childhood illness, and psychopathology in late childhood and adolescence. Child Development, 60, 701–709.PubMedCrossRef

DeVincent, C. J., Gadow, K. D., Delosh, D., & Geller, L. (2007). Sleep disturbance and its relation to DSM-IV psychiatric symptoms in preschool-aged children with pervasive developmental disorder and community controls. Journal of Child Neurology, 22, 161–169.PubMedCrossRef

DeVincent, C., Gadow, K. D., Strong, G., Schwartz, J., & Cuva, S. (2008). Screening for autism spectrum disorder with the Early Childhood Inventory-4. Journal of Developmental and Behavioral Pediatrics, 29, 1–10.PubMed

Dick, D. M., Viken, R. J., Kaprio, J., Pulkkinen, L., & Rose, R. J. (2005). Understanding the covariation among childhood externalizing symptoms: Genetic and environmental influences on conduct disorder, attention deficit hyperactivity disorder, and oppositional defiant disorder symptoms. Journal of Abnormal Child Psychology, 33, 219–229.PubMedCrossRef

Drabick, D. A. G., Beauchaine, T. P., Gadow, K. D., Carlson, G. A., & Bromet, E. J. (2006). Risk factors for conduct problems and depressive symptoms in a cohort of Ukrainian children. Journal of Clinical Child and Adolescent Psychology, 35, 244–252.PubMedCrossRef

Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G., & Munoz, R. (1972). Diagnostic criteria for use in psychiatric research. Archives General Psychiatry, 26, 57–63.

Ford, T., Goodman, R., & Meltzer, H. (2004). The relative importance of child, family, school and neighborhood correlates of childhood psychiatric disorder. Social Psychiatry Psychiatric Epidemiology, 39, 487–496.CrossRef

Gadow, K. D., & DeVincent, C. J. (2005). Clinical significance of tics and attention-deficit hyperactivity disorder (ADHD) in children with pervasive developmental disorder. Journal of Child Neurology, 20, 481–488.PubMed

Gadow, K. D., DeVincent, C. J., & Drabick, D. A. G. (a-in press). Oppositional defiant disorder as a clinical phenotype in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders.

Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2006). ADHD symptom subtypes in children with pervasive developmental disorder. Journal of Autism and Developmental Disorders, 36, 271–283.PubMedCrossRef

Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2004a). Psychiatric symptoms in preschool children with PDD and clinic and comparison samples. Journal of Autism and Developmental Disorders, 34, 379–393.PubMedCrossRef

Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-aged children with PDD versus clinic and community samples. Autism, 9, 392–415.PubMedCrossRef

Gadow, K. D., Drabick, D. A. G., Loney, J., Sprafkin, J., Salisbury, H., Azizian, A., & Schwartz, J. (2004b). Comparison of ADHD symptom subtypes as source-specific syndromes. Journal of Child Psychology and Psychiatry, 45, 1135–1149.PubMedCrossRef

Gadow, K. D., & Nolan, E. E. (2002). Differences between preschool children with ODD, ADHD, and ODD + ADHD symptoms. Journal of Child Psychology and Psychiatry, 43, 191–201.PubMedCrossRef

Gadow, K. D., Nolan, E. E., Sprafkin, J., & Schwartz, J. (2002). Tics and psychiatric comorbidity in children and adolescents. Developmental Medicine & Child Neurology, 44, 330–338.CrossRef

Gadow, K. D., Schwartz, J., DeVincent, C., Strong, G., & Cuva, S. (b-in press). Clinical utility of autism spectrum disorder scoring algorithms for the Child Symptom Inventory. Journal of Autism and Developmental Disorders.

Gadow, K. D., & Sprafkin, J. (1994). Child symptom inventories manual. Stony Brook, NY: Checkmate Plus.

Gadow, K. D., & Sprafkin, J. (2002). Child symptom inventory-4 screening and norms manual. Stony Brook, NY: Checkmate Plus.

Gadow, K. D., & Sprafkin, J. (2007). The symptom inventories: An annotated bibliography [On-line]. Available: www.checkmateplus.com

Gericke, G. S. (2006). Chromosomal fragility, structural rearrangements and mobile element activity may reflect dynamic epigenetic mechanisms of importance in neurobehavioral genetics. Medical Hypotheses, 66, 276–285.PubMedCrossRef

Goodman, S. H., Hoven, C. W., Narrow, W. E., Cohen, P., Fielding, B., Alegria, M., Leaf, P. J., Kandel, D., Horwitz, S. M., Bravo, M., Moore, R., & Dulcan, M. K. (1998). Measurement of risk for mental disorders and competence in a psychiatric epidemiologic community survey: The National Institute of Mental Health Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) study. Social Psychiatry Psychiatric Epidemiology, 33, 162–173.CrossRef

Gottesman, I. I., & Gould, T. D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry, 160, 636–645.PubMedCrossRef

Gurney, J. G., McPheeters, M. L., & Davis, M. M. (2007). Parental report of health conditions and health care use among children with and without autism. Archives of Pediatric and Adolescent Medicine, 160, 825–830.CrossRef

Hill, J. (2002). Biological, psychological and social processes in the conduct disorders. Journal of Child Psychology & Psychiatry, 43, 133–164.CrossRef

Hollingshead, A. B. (1975). Four factor index of social status. New Haven, CT: Department of Sociology, Yale University.

Kandel, E., & Mednick, S. A. (1991). Perinatal complications predict violent offending. Criminology, 29, 519–529.CrossRef

Kendler, K. S. (2005). Psychiatric genetics: A methodologic critique. American Journal of Psychiatry, 162, 3–11.PubMedCrossRef

Klin, A., Lang, J., Cicchetti, D. V., & Volkmar, F. R. (2000). Brief report: Interrater reliability of clinical diagnoses and DSM-IV criteria for autistic disorder: Results of the DSM-IV autism field trial. Journal of Autism and Developmental Disorders, 30, 163–167.PubMedCrossRef

Koskentausta, M., Iivanainen, M., & Almquist, F. (2007). Risk factors for psychiatric disturbance in children with intellectual disability. Journal of Intellectual Disability Research, 51, 43–53.PubMedCrossRef

Lauritsen, M. B., Pedersen, C. B., & Mortensen, P. B. (2005). Effects of familial risk factors and place of birth on the risk of autism: A nation-wide register-based study. Journal of Child Psychology and Psychiatry, 46, 963–971.PubMedCrossRef

Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.PubMedCrossRef

Martin, A., Scahill, L., Klin, A., & Volkmar, F. R. (1999). Higher-functioning pervasive developmental disorders: Rates and patterns of psychotropic drug use. Journal of Child and Adolescent Psychiatry, 38, 923–931.CrossRef

Martin, N., Scourfield, J., & McGuffin, P. (2002). Observer effects and heritability of childhood attention-deficit hyperactivity disorder symptoms. British Journal of Psychiatry, 180, 260–265.PubMedCrossRef

O’Callaghan, E., Karkin, C., & Waddinggton, J. L. (1990). Obstetric complications in schizophrenia and the validity of maternal recall. Psychological Medicine, 20, 89–94.PubMed

Offord, D. R., Boyle, M. H., Racine, Y., Szatmari, P., Fleming, J. E., Sanford, M., & Lipman, E. L. (1996). Integrating assessment data from multiple informants. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 1078–1085.PubMedCrossRef

Robins, E., & Guze, S. B. (1970). Establishment of diagnostic validity in psychiatric illness: Its application to schizophrenia. American Journal of Psychiatry, 126, 983–987.PubMed

Rutter, M., Moffitt, T. E., & Caspi, A. (2006). Gene-environment interplay and psychopathology: Multiple varieties but real effects. Journal of Child Psychology and Psychiatry, 47, 226–261.PubMedCrossRef

Rzhetsky, A., Wajngurt, D., Park, N., & Zheng, T. (2007). Probing genetic overlap among complex human phenotypes. Proceedings of the National Association of Science, 104, 11694–11699.CrossRef

Sprafkin, J., Volpe, R. J., Gadow, K. D., Nolan, E. E., & Kelly, K. (2002). A DSM-IV-referenced screening instrument for preschool children: The Early Childhood Inventory-4. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 604–612.PubMedCrossRef

Sprich-Buckminster, S., Biederman, J., Milberger, S., Faraone, S. V., & Lehman, B. K. (1993). Are perinatal complications relevant to the manifestations of ADD? Issues of comorbidity and familiality. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 1032–1037.PubMedCrossRef

Sukhodolsky, D. G., Scahill, L., Gadow, K. D., Arnold, L. E., Aman, M. G., McDougle, C. J., MacCracken, J. T., Tierney, E., White, S. W, Lecavalier, L., & Vitiello, B. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36, 117–128.PubMedCrossRef

Szatmari, P., MacLean, J. E., Jones, M. B., Bryson, S. E., Zwaigenbaum, L., Bartolucci, G., Mahoney, W. J., & Tuff, L. (2000). The familial aggregation of the lesser variant in biological and nonbiological relatives of PDD probands: A family history study. Journal of Child Psychology and Psychiatry, 41, 579–586.PubMedCrossRef

Szatmari, P., Reitsma-Street, M., & Offord, D. R. (1986). Pregnancy and birth complications in antisocial adolescents and their siblings. Canadian Journal of Psychiatry, 31, 513–516.

Sverd, J. (2003). Psychiatric disorders in individuals with pervasive developmental disorder. Journal of Psychiatric Practice, 9, 111–127.PubMedCrossRef

Thapar, A., O’Donovan, M., & Owen, M. J. (2005). The genetics of attention deficit hyperactivity disorder. Human Molecular Genetics, 14(review Issue 2), R275–R282.PubMedCrossRef

Weisbrot, D. M., Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15, 477–496.PubMedCrossRef

Witwer, A., & Lecavalier, L. (2005). Treatment incidence and patterns in children and adolescents with autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology, 15, 671–681.PubMedCrossRef

Wozniak, J., Biederman, J., Faraone, S. V., Frazier, J., Kim, J., Millstein, R., Gershon, J., Thornell, A., Cha, K., & Snyder, J. B. (1997). Mania in children with pervasive developmental disorder revisited. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 1552–1559.PubMedCrossRef

Yirmiya, N., & Shaked, M. (2005). Psychiatric disorders in parents of children with autism: A meta-analysis. Journal of Child Psychology and Psychiatry, 46, 69–83.PubMedCrossRef

Zwaigenbaum, L., Szatmari, P., Jones, M. B., Bryson, S. E., MacLean, J. E., Mahoney, W. J., Bartolucci, G., & Tuff, L. (2002). Pregnancy and birth complications in autism and liability to the broader autism phenotype. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 572–579.PubMedCrossRef

Titel: Predictors of Psychiatric Symptoms in Children with an Autism Spectrum Disorder
Publicatiedatum: 01-10-2008
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 9/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-008-0556-8

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 9/2008

Rachel Forrester-Jones and Sarah Broadhurst, Autism and Loss

When Prototypes Are Not Best: Judgments Made by Children with Autism

The Role of Face Familiarity in Eye Tracking of Faces by Individuals with Autism Spectrum Disorders

Examining the Validity of Autism Spectrum Disorder Subtypes

Quality of Life of Adults with Pervasive Developmental Disorders and Intellectual Disabilities

Sleep Patterns in School-age Children with Asperger Syndrome or High-functioning Autism: A Follow-up Study