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Gepubliceerd in: Quality of Life Research 11/2015

24-05-2015

Predicting factors of health-related quality of life in octogenarians: a 3-year follow-up longitudinal study

Auteurs: Assumpta Ferrer, Francesc Formiga, Oriol Cunillera, M. Jesús Megido, Xavier Corbella, Jesús Almeda, Octabaix Study Group

Gepubliceerd in: Quality of Life Research | Uitgave 11/2015

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Abstract

Purpose

The proportion of very old people is rising, and so, describing their health-related quality of life (HRQoL) is an important point of interest. The aim of this study was to analyse the predictive factors on HRQoL throughout a 3-year follow-up period, in a community-based cohort of octogenarian people.

Methods

From 290 subjects aged 85 and over, sociodemographic and geriatric data, including levels of frailty phenotype assessment, and HRQoL using the EuroQol 5D3L (EQ-5D) instrument were collected. A longitudinal analysis was performed by generalized estimating equations (jointly testing the bivariate effect of variables and its time dependence) and regression mixed models to evaluate the adjusted effect of variables on HRQoL after a 3-year follow-up.

Results

In the EQ-5D baseline assessment, the average visual analogue self-rating scale value was 63.82 (SD ± 19.45), the EQ-5D index was 0.67 (0.34) and the most significant issues were pain/discomfort (61.2 %), depression (45.3 %) and mobility (44.6 %). The third year index was 0.55 (0.38). Independent predictive factors of a lower HRQoL identified by the regression mixed models were female gender (marginal effect ME = −0.101; p = 0.003), being pre-frail (ME = −0.142; p = 0.011) or frail (ME = −0.071; p = 0.030), having heart failure (ME = −0.081; p = 0.037) and having a high social risk score (ME = −0.020; p = 0.015). In contrast, higher functional status (ME = 0.050; p < 0.001) and nutritional score (ME = 0.013; p = 0.011) appeared to be predictive factors of an enhanced HRQoL. The adjusted effect of “time of follow-up” had no statistical significance.

Conclusion

Frail individuals at baseline have a significant lower HRQoL, whereas a higher functional status and nutritional status are independent predicting factors of an enhanced HRQoL after 3 years of follow-up. These findings may encourage clinicians in order to asses HRQoL.
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Literatuur
2.
go back to reference Rechel, B., Grundy, E., Robine, J. M., Cylus, J., Mackenbach, J. P., Knai, C., et al. (2013). Ageing in the European Union. Lancet, 381, 1312–1322.CrossRefPubMed Rechel, B., Grundy, E., Robine, J. M., Cylus, J., Mackenbach, J. P., Knai, C., et al. (2013). Ageing in the European Union. Lancet, 381, 1312–1322.CrossRefPubMed
3.
go back to reference Jagger, C., Matthews, R., Matthews, F., Robinson, T., Robine, J. M., & Brayne, C. (2007). Medical Research Council Cognitive Function and Ageing Study Investigators. The burden of diseases on disability-free life expectancy in later life. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 62, 408–414.CrossRef Jagger, C., Matthews, R., Matthews, F., Robinson, T., Robine, J. M., & Brayne, C. (2007). Medical Research Council Cognitive Function and Ageing Study Investigators. The burden of diseases on disability-free life expectancy in later life. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 62, 408–414.CrossRef
4.
go back to reference Dening, T. R., Chi, L. Y., Brayne, C., Huppert, F. A., Paykel, E. S., & O’Connor, D. W. (1998). Changes in self-rated health, disability and contact with services in a very elderly cohort: A 6-year follow-up study. Age and Ageing, 27, 23–33.CrossRefPubMed Dening, T. R., Chi, L. Y., Brayne, C., Huppert, F. A., Paykel, E. S., & O’Connor, D. W. (1998). Changes in self-rated health, disability and contact with services in a very elderly cohort: A 6-year follow-up study. Age and Ageing, 27, 23–33.CrossRefPubMed
5.
go back to reference Ploeg, J., Brazil, K., Hutchison, B., Kaczorowski, J., Dalby, D. M., Goldsmith, C. H., et al. (2010). Effect of preventive primary care outreach on health related quality of life among older adults at risk of functional decline: Randomised controlled trial. BMJ, 16(340), c1480.CrossRef Ploeg, J., Brazil, K., Hutchison, B., Kaczorowski, J., Dalby, D. M., Goldsmith, C. H., et al. (2010). Effect of preventive primary care outreach on health related quality of life among older adults at risk of functional decline: Randomised controlled trial. BMJ, 16(340), c1480.CrossRef
6.
go back to reference Lapid, M. I., Rummans, T. A., Boeve, B. F., McCormick, J. K., Pankratz, V. S., Cha, R. H., et al. (2011). What is the quality of life in the oldest old? International Psychogeriatrics, 23, 1003–1010.PubMedCentralCrossRefPubMed Lapid, M. I., Rummans, T. A., Boeve, B. F., McCormick, J. K., Pankratz, V. S., Cha, R. H., et al. (2011). What is the quality of life in the oldest old? International Psychogeriatrics, 23, 1003–1010.PubMedCentralCrossRefPubMed
7.
go back to reference Liao, Y., McGee, D. L., Cao, G., & Cooper, R. S. (2000). Quality of the last year of life of older adults: 1986 versus 1993. JAMA, 283, 512–518.CrossRefPubMed Liao, Y., McGee, D. L., Cao, G., & Cooper, R. S. (2000). Quality of the last year of life of older adults: 1986 versus 1993. JAMA, 283, 512–518.CrossRefPubMed
8.
go back to reference O’Boyle, C. A. (1997). Measuring the quality of later life. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 352, 1871–1879.PubMedCentralCrossRefPubMed O’Boyle, C. A. (1997). Measuring the quality of later life. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 352, 1871–1879.PubMedCentralCrossRefPubMed
9.
go back to reference Orfila, F., Ferrer, M., Lamarca, R., & Alonso, J. (2000). Evolution of self-rated health status in the elderly: Cross-sectional versus longitudinal estimates. Journal of Clinical Epidemiology, 53, 563–570.CrossRefPubMed Orfila, F., Ferrer, M., Lamarca, R., & Alonso, J. (2000). Evolution of self-rated health status in the elderly: Cross-sectional versus longitudinal estimates. Journal of Clinical Epidemiology, 53, 563–570.CrossRefPubMed
10.
go back to reference Szanton, S. L., Thorpe, R. J., Boyd, C., Tanner, E. K., Leff, B., Agree, E., et al. (2011). Community aging in place, advancing better living for elders: A bio-behavioral-environmental intervention to improve function and health-related quality of life in disabled older adults. Journal of the American Geriatrics Society, 59, 2314–2320.PubMedCentralCrossRefPubMed Szanton, S. L., Thorpe, R. J., Boyd, C., Tanner, E. K., Leff, B., Agree, E., et al. (2011). Community aging in place, advancing better living for elders: A bio-behavioral-environmental intervention to improve function and health-related quality of life in disabled older adults. Journal of the American Geriatrics Society, 59, 2314–2320.PubMedCentralCrossRefPubMed
11.
go back to reference Boyd, C. M., Xue, Q. L., Simpson, C. F., Guralnik, J. M., & Fried, L. P. (2005). Frailty, hospitalization, and progression of disability in a cohort of disabled older women. American Journal of Medicine, 118, 1225–1231.CrossRefPubMed Boyd, C. M., Xue, Q. L., Simpson, C. F., Guralnik, J. M., & Fried, L. P. (2005). Frailty, hospitalization, and progression of disability in a cohort of disabled older women. American Journal of Medicine, 118, 1225–1231.CrossRefPubMed
12.
go back to reference Chou, C. H., Hwang, C. L., & Wu, Y. T. (2012). Effect of exercise on physical function, daily living activities, and quality of life in the frail older adults: A meta-analysis. Archives of Physical Medicine and Rehabilitation, 93, 237–244.CrossRefPubMed Chou, C. H., Hwang, C. L., & Wu, Y. T. (2012). Effect of exercise on physical function, daily living activities, and quality of life in the frail older adults: A meta-analysis. Archives of Physical Medicine and Rehabilitation, 93, 237–244.CrossRefPubMed
13.
go back to reference Ishimoto, Y., Wada, T., Hirosaki, M., Kasahara, Y., Kimura, Y., Konno, A., et al. (2009). Health-related differences between participants and nonparticipants in community-based geriatric examinations. Journal of the American Geriatrics Society, 57, 360–362.CrossRefPubMed Ishimoto, Y., Wada, T., Hirosaki, M., Kasahara, Y., Kimura, Y., Konno, A., et al. (2009). Health-related differences between participants and nonparticipants in community-based geriatric examinations. Journal of the American Geriatrics Society, 57, 360–362.CrossRefPubMed
14.
go back to reference Layte, R., Sexton, E., & Savva, G. (2013). Quality of life in older age: Evidence from an Irish cohort study. Journal of the American Geriatrics Society, 61(s2), S299–S305.CrossRefPubMed Layte, R., Sexton, E., & Savva, G. (2013). Quality of life in older age: Evidence from an Irish cohort study. Journal of the American Geriatrics Society, 61(s2), S299–S305.CrossRefPubMed
15.
go back to reference Ferrer, A., Formiga, F., Almeda, J., Alonso, J., Brotons, C., & Pujol, R. (2010). Health-related quality of life in nonagenarians: Gender, functional status and nutritional risk as associated factors. Medicina Clinica (Barc), 134, 303–306.CrossRef Ferrer, A., Formiga, F., Almeda, J., Alonso, J., Brotons, C., & Pujol, R. (2010). Health-related quality of life in nonagenarians: Gender, functional status and nutritional risk as associated factors. Medicina Clinica (Barc), 134, 303–306.CrossRef
16.
go back to reference Ferrer, A., Padrós, G., Formiga, F., Rojas-Farreras, S., Perez, J. M., & Pujol, R. (2012). Diabetes mellitus: Prevalence and impact of morbidities in the oldest old. The octabaix study. Journal of the American Geriatrics Society, 60, 462–467.CrossRefPubMed Ferrer, A., Padrós, G., Formiga, F., Rojas-Farreras, S., Perez, J. M., & Pujol, R. (2012). Diabetes mellitus: Prevalence and impact of morbidities in the oldest old. The octabaix study. Journal of the American Geriatrics Society, 60, 462–467.CrossRefPubMed
17.
go back to reference Mahoney, F. I., & Barthel, D. W. (1965). Functional evaluation: The Barthel Index. A simple index of independence useful in scoring improvement in the rehabilitation of the chronically ill. Md State Medical Journal, 14, 61–65. Mahoney, F. I., & Barthel, D. W. (1965). Functional evaluation: The Barthel Index. A simple index of independence useful in scoring improvement in the rehabilitation of the chronically ill. Md State Medical Journal, 14, 61–65.
18.
go back to reference Lawton, M. P., & Brody, E. M. (1969). Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179–186.CrossRefPubMed Lawton, M. P., & Brody, E. M. (1969). Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179–186.CrossRefPubMed
19.
go back to reference Lobo, A., Saz, P., Marcos, G., Día, J. L., de la Cámara, C., Ventura, T., et al. (1999). Revalidación y normalización del Mini-Examen Cognoscitivo (primera versión en castellano del Mini-mental Status Examination) en la población general geriátrica. Medicina Clinica (Barc), 112, 767–774. Lobo, A., Saz, P., Marcos, G., Día, J. L., de la Cámara, C., Ventura, T., et al. (1999). Revalidación y normalización del Mini-Examen Cognoscitivo (primera versión en castellano del Mini-mental Status Examination) en la población general geriátrica. Medicina Clinica (Barc), 112, 767–774.
20.
go back to reference Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987). A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Journal of Chronic Diseases, 40, 373–375.CrossRefPubMed Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987). A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Journal of Chronic Diseases, 40, 373–375.CrossRefPubMed
21.
go back to reference Guigoz, Y. (2006). The mini nutritional assessment (MNA) review of the literature–What does it tell us? Journal of Nutrition Health and Aging, 10, 466–485. Guigoz, Y. (2006). The mini nutritional assessment (MNA) review of the literature–What does it tell us? Journal of Nutrition Health and Aging, 10, 466–485.
22.
go back to reference Alarcón, M. T., & González, J. I. (1998). La escala sociofamiliar de Gijón, instrumento útil en el hospital general. Review Esp Geriatr Gerontol, 33, 178–180. Alarcón, M. T., & González, J. I. (1998). La escala sociofamiliar de Gijón, instrumento útil en el hospital general. Review Esp Geriatr Gerontol, 33, 178–180.
23.
go back to reference Badia, X., Roset, M., Herdman, M., & Kind, P. (2001). A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Medical Decision Making, 21, 7–16.CrossRefPubMed Badia, X., Roset, M., Herdman, M., & Kind, P. (2001). A comparison of United Kingdom and Spanish general population time trade-off values for EQ-5D health states. Medical Decision Making, 21, 7–16.CrossRefPubMed
24.
go back to reference Schafer, J. L. (1999). Multiple imputation: A primer. Statistical Methods in Medical Research, 8, 3–15.CrossRefPubMed Schafer, J. L. (1999). Multiple imputation: A primer. Statistical Methods in Medical Research, 8, 3–15.CrossRefPubMed
25.
go back to reference Fritz, T., Caidahl, K., Krook, A., Lundström, P., Mashili, F., Osler, M., et al. (2013). Effects of Nordic walking on cardiovascular risk factors in overweight individuals with type 2 diabetes, impaired or normal glucose tolerance. Diabetes Metabolism Research Reviews, 29, 25–32.CrossRefPubMed Fritz, T., Caidahl, K., Krook, A., Lundström, P., Mashili, F., Osler, M., et al. (2013). Effects of Nordic walking on cardiovascular risk factors in overweight individuals with type 2 diabetes, impaired or normal glucose tolerance. Diabetes Metabolism Research Reviews, 29, 25–32.CrossRefPubMed
26.
go back to reference Collerton J, Davies K, Jagger C, Kingston A, Bond J, Eccles MP et al. (2009) Health and disease in 85 year olds: Baseline findings from the Newcastle 85+ cohort study. BMJ 339 b4904. Collerton J, Davies K, Jagger C, Kingston A, Bond J, Eccles MP et al. (2009) Health and disease in 85 year olds: Baseline findings from the Newcastle 85+ cohort study. BMJ 339 b4904.
27.
go back to reference Pepine, C. J. (2013). Effects of pharmacologic therapy on health-related quality of life in elderly patients with atrial fibrillation: A systematic review of randomized and nonrandomized trials. Clinical Medicine Insights Cardiology, 7, 1–20.PubMedCentralCrossRefPubMed Pepine, C. J. (2013). Effects of pharmacologic therapy on health-related quality of life in elderly patients with atrial fibrillation: A systematic review of randomized and nonrandomized trials. Clinical Medicine Insights Cardiology, 7, 1–20.PubMedCentralCrossRefPubMed
28.
go back to reference Azpiazu, M., Cruz, A., Villagrasa, J. R., Abanades, J. C., García, N., & Alvarez, C. (2003). Quality of life in noninstitutionalized persons older than 65 years in two health care districts in Madrid. Atencion Primaria, 31, 285–292.CrossRef Azpiazu, M., Cruz, A., Villagrasa, J. R., Abanades, J. C., García, N., & Alvarez, C. (2003). Quality of life in noninstitutionalized persons older than 65 years in two health care districts in Madrid. Atencion Primaria, 31, 285–292.CrossRef
29.
go back to reference De Rivas, B., Permanyer-Miralda, G., Brotons, C., Brotons, C., Aznar, J., & Sobreviela, E. (2008). Health-related quality of life in unselected outpatients with heart failure across Spain in two different health care levels. Magnitude and determinants of impairment: The INCA study. Quality of Life Research, 17, 1229–1238.CrossRefPubMed De Rivas, B., Permanyer-Miralda, G., Brotons, C., Brotons, C., Aznar, J., & Sobreviela, E. (2008). Health-related quality of life in unselected outpatients with heart failure across Spain in two different health care levels. Magnitude and determinants of impairment: The INCA study. Quality of Life Research, 17, 1229–1238.CrossRefPubMed
30.
go back to reference Westlake, C., Dracup, K., Creaser, J., et al. (2002). Correlates of health-related quality of life in patients with heart failure. Heart and Lung, 3, 85–93.CrossRef Westlake, C., Dracup, K., Creaser, J., et al. (2002). Correlates of health-related quality of life in patients with heart failure. Heart and Lung, 3, 85–93.CrossRef
31.
go back to reference Van der Weele, G. M., Gussekloo, J., De Waal, M. W., De Craen, A. J., & Van der Mast, R. C. (2008). Co-occurrence of depression and anxiety in elderly subjects aged 90 years and its relationship with functional status, quality of life and mortality. International Journal of Geriatric Psychiatry, 21, 2162. Van der Weele, G. M., Gussekloo, J., De Waal, M. W., De Craen, A. J., & Van der Mast, R. C. (2008). Co-occurrence of depression and anxiety in elderly subjects aged 90 years and its relationship with functional status, quality of life and mortality. International Journal of Geriatric Psychiatry, 21, 2162.
32.
go back to reference Kanauchi, M., Kubo, A., Kanauchi, K., & Saito, Y. (2008). Frailty, health-related quality of life and mental well-being in older adults with cardiometabolic risk factors. International Journal of Clinical Practice, 62, 1447–1451. Kanauchi, M., Kubo, A., Kanauchi, K., & Saito, Y. (2008). Frailty, health-related quality of life and mental well-being in older adults with cardiometabolic risk factors. International Journal of Clinical Practice, 62, 1447–1451.
33.
go back to reference Whitehead, S. J., & Ali, S. (2010). Health outcomes in economic evaluation: The QALY and utilities. British Medical Bulletin, 96, 5–21.CrossRefPubMed Whitehead, S. J., & Ali, S. (2010). Health outcomes in economic evaluation: The QALY and utilities. British Medical Bulletin, 96, 5–21.CrossRefPubMed
34.
go back to reference Erceg, P., Despotovic, N., Milosevic, D. P., Soldatovic, I., Zdravkovic, S., Tomic, S., et al. (2013). Health-related quality of life in elderly patients hospitalized with chronic heart failure. Clinical Interventions in Aging, 8, 1539–1546.PubMedCentralCrossRefPubMed Erceg, P., Despotovic, N., Milosevic, D. P., Soldatovic, I., Zdravkovic, S., Tomic, S., et al. (2013). Health-related quality of life in elderly patients hospitalized with chronic heart failure. Clinical Interventions in Aging, 8, 1539–1546.PubMedCentralCrossRefPubMed
35.
go back to reference Shyu, Y. I., Liang, J., Tseng, M. Y., Li, H. J., Wu, C. C., Cheng, H. S., et al. (2013). Comprehensive and subacute care interventions improve health-related quality of life for older patients after surgery for hip fracture: A randomised controlled trial”. CT. International Journal of Nursing Studies, 50, 1013–1024.CrossRefPubMed Shyu, Y. I., Liang, J., Tseng, M. Y., Li, H. J., Wu, C. C., Cheng, H. S., et al. (2013). Comprehensive and subacute care interventions improve health-related quality of life for older patients after surgery for hip fracture: A randomised controlled trial”. CT. International Journal of Nursing Studies, 50, 1013–1024.CrossRefPubMed
Metagegevens
Titel
Predicting factors of health-related quality of life in octogenarians: a 3-year follow-up longitudinal study
Auteurs
Assumpta Ferrer
Francesc Formiga
Oriol Cunillera
M. Jesús Megido
Xavier Corbella
Jesús Almeda
Octabaix Study Group
Publicatiedatum
24-05-2015
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 11/2015
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-015-1004-9

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