Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-12-2012 | Original Paper

Predicting Developmental Status from 12 to 24 Months in Infants at Risk for Autism Spectrum Disorder: A Preliminary Report

Auteurs: Suzanne L. Macari, Daniel Campbell, Grace W. Gengoux, Celine A. Saulnier, Ami J. Klin, Katarzyna Chawarska

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2012

Abstract

The study examined whether performance profiles on individual items of the Toddler Module of the Autism Diagnostic Observation Schedule at 12 months are associated with developmental status at 24 months in infants at high and low risk for developing Autism Spectrum Disorder (ASD). A nonparametric decision-tree learning algorithm identified sets of 12-month predictors of developmental status at 24 months. Results suggest that identification of infants who are likely to exhibit symptoms of ASD at 24 months is complicated by variable patterns of symptom emergence. Fine-grained analyses linking specific profiles of strengths and deficits with specific patterns of symptom emergence will be necessary for further refinement of screening and diagnostic instruments for ASD in infancy.

vorige artikel Rating Parent–Child Interactions: Joint Engagement, Communication Dynamics, and Shared Topics in Autism, Down Syndrome, and Typical Development

volgende artikel Daytime Secretion of Salivary Cortisol and Alpha-Amylase in Preschool-Aged Children with Autism and Typically Developing Children

A score of 2 on this item indicates: “Engaged only when the examiner works hard to get and keep the child’s interest OR child is only engaged during snack.” A score of 3 is coded when the child is: “Not engaged at all, even when examiner makes efforts to attract the child’s interest OR the child is only engaged during games involving physical contact.”.

American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th edn., text revision). Washington, DC: Author.

Bailey, A., Phillips, W., & Rutter, M. (1996). Autism: Towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. Journal of Child Psychology and Psychiatry, 37(1), 89–126.PubMedCrossRef

Bates, E., Benigni, L., Bretherton, L., Camaioni, L., & Volterra, V. (1979). The emergence of symbols: Cognition and communication in infancy. New York: Academic Press.

Breiman, L., Friedman, J., Olshen, R., & Stone, C. (1984). Classification and regression trees. New York, NY: Wadsworth.

Bryson, S. E., Zwaigenbaum, L., Brian, J., Roberts, W., Szatmari, P., Rombough, V., et al. (2007). A prospective case series of high-risk infants who developed autism. Journal of Autism and Developmental Disorders, 37(1), 12–24.PubMedCrossRef

Carpenter, M., Nagell, K., Tomasello, M., Butterworth, G., & Moore, C. (1998). Social cognition, joint attention, and communicative competence from 9 to 15 months of age. Monographs of the society for research in child development, 63(4), 1–143.CrossRef

Carr, T., Colombi, C., MacDonald, M., & Lord, C. (2011). Measuring response to intervention with the autism diagnostic observation schedule-change (ADOS-C). Presented at the Society for Research in Child Development: Montreal, CA.

Charman, T., Taylor, E., Drew, A., Cockerill, H., Brown, J.-A., & Baird, G. (2005). Outcome at 7 years of children diagnosed with autism at age 2: Predictive validity of assessments conducted at 2 and 3 years of age and pattern of symptom change over time. Journal of Child Psychology and Psychiatry, 46(5), 500–513.PubMedCrossRef

Chawarska, K., Klin, A., Paul, R., Macari, S., & Volkmar, F. (2009). A prospective study of toddlers with ASD: Short-term diagnostic and cognitive outcomes. Journal of Child Psychology and Psychiatry, 50(10), 1235–1245.PubMedCrossRef

Chawarska, K., Klin, A., Paul, R., & Volkmar, F. (2007). Autism Spectrum Disorder in the second year: Stability and change in syndrome expression. Journal of Child Psychology and Psychiatry, 48(2), 128–138.PubMedCrossRef

Chawarska, K., Macari, S., & Shic, F. (2012). Context modulates attention to social scenes in toddlers with autism. [Electronic version]. Journal of Child Psychology and Psychiatry.

Chawarska, K. & Shic, F. (2009). Looking but not seeing: Abnormal visual scanning and recognition of faces in 2 and 4-year old children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 39(12), 1663–1672.PubMedCrossRef

Colombi, C., Carr, T., MacDonald, M., & Lord, C. (2011). Developing a measure of treatment outcome: The Autism Diagnostic Observation Schedule-Change. Presented at the Society for Research in Child Development, Montreal, CA.

Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., et al. (2010). Randomized, controlled trial of an intervention for toddlers with autism: The early start denver model. Pediatrics, 125(1), e17–e23.PubMedCrossRef

Eisenberg, L., & Kanner, L. (1956). Early infantile autism, 1943–55. American Journal of Orthopsychiatry, 26, 556–566.PubMedCrossRef

Gamliel, I., Yirmiya, N., & Sigman, M. (2007). The development of young siblings of children with autism from 4 to 54 Months. Journal of Autism and Developmental Disorders, 37(1), 171–183.PubMedCrossRef

Gengoux, G. W., Steiner, A. M., & Chawarska, K. (2010). Parent stress related to infants at-risk for Autism Spectrum Disorder. Presented at the International Meeting for Autism Research, Philadelphia, PA.

Hastie, T., Tibshirani, R., & Friedman, J. (2009). The elements of statistical learning: Data mining, inference, and prediction (2nd ed.). New York, NY: Springer.

Jones, W., Carr, K., & Klin, A. (2008). Absence of preferential looking to the eyes of approaching adults predicts level of social disability in 2-year-olds with autism spectrum disorder. Archives of General Psychiatry, 65, 946–954.PubMedCrossRef

Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217–250.

Landa, R., & Garrett-Mayer, E. (2006). Development in infants with Autism Spectrum Disorders: A prospective study. Journal of Child Psychology and Psychiatry, 47(6), 629–638.PubMedCrossRef

Landa, R. J., Holman, K. C., & Garrett-Mayer, E. (2007). Social and communication development in toddlers with early and later diagnosis of Autism Spectrum Disorders. Archives of General Psychiatry, 64(7), 853.PubMedCrossRef

Lord, C., Luyster, R., Gotham, K., Guthrie, W., Risi, S., & Rutter, M. (in press). Autism diagnostic observation schedule—toddler module manual. Los Angeles, CA: Western Psychological Services.

Lord, C., Risi, S., DiLavore, P. S., Shulman, C., Thurm, A., & Pickles, A. (2006). Autism from 2 to 9 years of age. Archives of General Psychiatry, 63(6), 694–701.PubMedCrossRef

Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule—generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef

Lord, C., Rutter, M., & LeCouteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659–685.PubMedCrossRef

Luyster, R., Gotham, K., Guthrie, W., Coffing, M., Petrak, R., Pierce, K., et al. (2009). The autism diagnostic observation schedule—toddler module: A new module of a standardized diagnostic measure for Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 39(9), 1305–1320.PubMedCrossRef

Mitchell, S., Brian, J., Zwaigenbaum, L., Roberts, W., Szatmari, P., Smith, I., et al. (2006). Early language and communication development of infants later diagnosed with Autism Spectrum Disorder. Journal of Developmental and Behavioral Pediatrics, 27(2), S69.PubMedCrossRef

Muhle, R., Trentacoste, S. V., & Rapin, I. (2004). The genetics of autism. Pediatrics, 113(5), e472–e486.PubMedCrossRef

Mullen, E. M. (1995). Mullen Scales of Early Learning. Circle Pines, MN: American Guidance Service.

Mundy, P., Sigman, M., & Kasari, C. (1994). Joint attention, developmental level, and symptom presentation in autism. Development and Psychopathology, 6(3), 389–401.CrossRef

Ozonoff, S., Heung, K., Byrd, R., Hansen, R., & Hertz-Picciotto, I. (2008a). The onset of autism: Patterns of symptom emergence in the first years of life. Autism Research, 1(6), 320–328.PubMedCrossRef

Ozonoff, S., Iosif, A. M., Baguio, F., Cook, I. C., Hill, M. M., Hutman, T., et al. (2010). A prospective study of the emergence of early behavioral signs of autism. Journal of the American Academy of Child and Adolescent Psychiatry, 49(3), 256–266.PubMed

Ozonoff, S., Macari, S., Young, G. S., Goldring, S., Thompson, M., & Rogers, S. J. (2008b). Atypical object exploration at 12 months of age is associated with autism in a prospective sample. Autism, 12(5), 457–472.PubMedCrossRef

Ozonoff, S., Williams, B. J., & Landa, R. (2005). Parental report of the early development of children with regressive autism. Autism, 9(5), 461–486.PubMedCrossRef

Ozonoff, S., Young, G. S., Carter, A., Messinger, D., Yirmiya, N., Zwaigenbaum, L., Bryson, S., et al. (2011a). Recurrence risk for Autism Spectrum Disorders: A Baby Siblings Research Consortium study. Pediatrics, 128, 2010–2825.

Ozonoff, S., Young, G. S., Hutman, T., Sigman, M., Rogers, S. J., Hill, M. M., Steinfeld, M. B., & Rozga, A. (2011b). Stability of ASD in a high risk sample. Paper presented at the Biennial Meeting of the Society for Research in Child Development (SRCD), Montreal.

Ozonoff, S., Young, G. S., Steinfeld, M. B., Hill, M. M., Cook, I., Hutman, T., et al. (2009). How early do parent concerns predict later autism diagnosis? Journal of Developmental and Behavioral Pediatrics, 30(5), 367.PubMedCrossRef

Paul, R., Fuerst, Y., Ramsay, G., Chawarska, K., & Klin, A. (2011). Out of the mouths of babes: Vocal production in infant siblings of children with ASD. Journal of Child Psychology and Psychiatry, 52(5), 588–598.PubMedCrossRef

Rozga, A., Hutman, T., Young, G. S., Rogers, S. J., Ozonoff, S., Dapretto, M., et al. (2011). Behavioral profiles of affected and unaffected siblings of children with autism: Contribution of measures of mother–infant interaction and nonverbal communication. Journal of Autism and Developmental Disorders, 41(3), 287–301.PubMedCrossRef

Shic, F., Bradshaw, J., Klin, A., Scassellati, B., & Chawarska, K. (2011). Limited activity monitoring in toddlers with autism spectrum disorder. Brain Research, 1380, 246–254.PubMedCrossRef

Siperstein, R., & Volkmar, F. (2004). Brief report: Parental reporting of regression in children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 34(6), 731–734.PubMedCrossRef

Stone, W. L., Coonrod, E. E., Turner, L. M., & Pozdol, S. L. (2004). Psychometric properties of the STAT for early autism screening. Journal of Autism and Developmental Disorders, 34(6), 691–701.PubMedCrossRef

Sullivan, M., Finelli, J., Marvin, A., Garrett-Mayer, E., Bauman, M., & Landa, R. (2007). Response to joint attention in toddlers at risk for Autism Spectrum Disorder: A prospective study. Journal of Autism and Developmental Disorders, 37(1), 37–48.PubMedCrossRef

Toth, K., Dawson, G., Meltzoff, A. N., Greenson, J., & Fein, D. (2007). Early social, imitation, play, and language abilities of young non-autistic siblings of children with autism. Journal of Autism and Developmental Disorders, 37(1), 145–157.PubMedCrossRef

Virkud, Y. V., Todd, R. D., Abbacchi, A. M., Zhang, Y., & Constantino, J. N. (2009). Familial aggregation of quantitative autistic traits in multiplex versus simplex autism. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 150B(3), 328–334.CrossRef

Volkmar, F., Chawarska, K., & Klin, A. (2007). Autism Spectrum Disorders in infants and toddlers: An introduction. Autism Spectrum Disorders in infants and toddlers: Diagnosis, assessment, and treatment (pp. 1–22). New York, NY: Guilford Press.

Werner, E., & Dawson, G. (2005). Validation of the phenomenon of autistic regression using home videotapes. Archives of General Psychiatry, 62(8), 889–895.PubMedCrossRef

Werner, E., Dawson, G., Munson, J., & Osterling, J. (2005). Variation in early developmental course in autism and its relation with behavioral outcome at 3–4 years of age. Journal of Autism and Developmental Disorders, 35(3), 337–350.PubMedCrossRef

Wetherby, A., Allen, L., Cleary, J., Kublin, K., & Goldstein, H. (2002). Validity and reliability of the Communication and Symbolic Behavior Scales Developmental Profile with very young children. Journal of Speech, Language and Hearing Research, 45(6), 1202–1218.CrossRef

Wetherby, A., Woods, J., Allen, L., Cleary, J., Dickinson, H., & Lord, C. (2004). Early indicators of Autism Spectrum Disorders in the second year of life. Journal of Autism and Developmental Disorders, 34, 473–493.PubMedCrossRef

Yoder, P., Stone, W. L., Walden, T., & Malesa, E. (2009). Predicting social impairment and ASD diagnosis in younger siblings of children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 39(10), 1381–1391.PubMedCrossRef

Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005). Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience, 23(2–3), 143–152.PubMedCrossRef

Titel: Predicting Developmental Status from 12 to 24 Months in Infants at Risk for Autism Spectrum Disorder: A Preliminary Report
Auteurs: Suzanne L. Macari
Daniel Campbell
Grace W. Gengoux
Celine A. Saulnier
Ami J. Klin
Katarzyna Chawarska
Publicatiedatum: 01-12-2012
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 12/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-012-1521-0

Andere artikelen Uitgave 12/2012

Implicit Social Learning in Relation to Autistic-Like Traits

Original Paper

The Problems We Take on: With an Integral Account of Autism

Book Review

An Early Social Engagement Intervention for Young Children with Autism and their Parents

Original Paper

Microglia in the Cerebral Cortex in Autism

Original Paper

Cognitive Control of Intentions for Voluntary Actions in Individuals With a High Level of Autistic Traits

Open Access
Original Paper

Cognitive Flexibility in ASD; Task Switching with Emotional Faces

Open Access
Original Paper