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2021 | OriginalPaper | Hoofdstuk

13. Posttraumatische stressstoornis

Auteurs : dr. Annette van Schagen, prof. dr. Eric Vermetten

Gepubliceerd in: Slaapstoornissen in de psychiatrie

Uitgeverij: Bohn Stafleu van Loghum

Samenvatting

De posttraumatische stressstoornis (PTSS) is een chronische stoornis die ontstaat bij ongeveer 10 % van de mensen na een ingrijpende gebeurtenis (o.a. met gevaar voor eigen leven en/of lichamelijke integriteit). Hoewel de gevaarlijke situatie voorbij is, persisteren herbelevingen van de gebeurtenis, hetgeen gepaard gaat met angst, emotionele onrust en vermijdingsgedrag. Het is een stoornis waarvan de symptomen bestaan uit een combinatie van fysieke manifestaties, zoals verhoogde arousal, spierspanning, schrikreacties en intrusieve ervaringen, alsook psychische manifestaties, zoals flashbacks, veranderde cognities en verstoorde emotieregulatie. Slaapproblemen zijn de belangrijkste klacht bij PTSS: nachtmerries worden het vaakst gerapporteerd, maar insomnie, slaapapneu, pavor nocturnus en nachtelijke arousals komen ook veel voor. In dit hoofdstuk gaan we in op de etiologie, prevalentie en diagnostiek van PTSS en slaapproblemen, hoe deze fenomenen elkaar versterken en wat dit betekent voor diagnostiek en behandeling.

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American Psychiatric Association (APA) (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: American Psychiatric Press.

Baglioni, C., Nanovska, S., Regen, W., Spiegelhalder, K., Feige, B., Nissen, C., et al. (2016). Sleep and mental disorders: A meta-analysis of polysomnographic research. Psychological Bulletin, 142(9), 969–990. https://doi.org/10.1037/bul0000053. CrossRefPubMedPubMedCentral

Baird, T., McLeay, S., Harvey, W., Theal, R., Law, D., & O’Sullivan, R. (2018). Sleep disturbances in Australian Vietnam veterans with and without posttraumatic stress disorder. Journal of Clinical Sleep Medicine, 14(5), 745–752. https://doi.org/10.5664/jcsm.7096. CrossRefPubMedPubMedCentral

Bajor, L. A., Ticlea, A. N., & Osser, D. N. (2011). The psychopharmacology algorithm project at the Harvard south shore program: An update on posttraumatic stress disorder. Harvard Review of Psychiatry, 19(5), 240–258. CrossRef

Belleville, G., Guay, S., & Marchand, A. (2009). Impact of sleep disturbances on PTSD symptoms and perceived health. The Journal of Nervous and Mental Disease, 197(2), 126–132. https://doi.org/10.1097/NMD.0b013e3181961d8e. CrossRefPubMed

Bisson, J. I., Cosgrove, S., Lewis, C., & Roberts, N. P. (2015). Post-traumatic stress disorder. BMJ, 351, h6161. https://doi.org/10.1136/bmj.h6161. CrossRefPubMedPubMedCentral

Boeschoten, M. A., Bakker, A., Jongedijk, R. A., Van Minnen, A., Elzinga, B. M., Rademaker, A. R., et al. (2014). Clinician-administered PTSD scale for DSM-5 Nederlandstalige versie [Dutch version]. https://www.psychotraumadiagnostics.centrum45.nl/nl/ptss.

Boeschoten, M. A., Van der Aa, N., Bakker, A., Ter Heide, F. J. J., Hoofwijk, M. C., Jongedijk, R. A., et al. (2018). Development and evaluation of the dutch clinician-administered PTSD scale for DSM-5 (CAPS-5). European Journal of Psychotraumatology, 9(1), 1546085. https://doi.org/10.1080/20008198.2018.1546085. CrossRefPubMedPubMedCentral

Brady, K. T., Killeen, T. K., Brewerton, T., & Lucerini, S. (2000). Comorbidity of psychiatric disorders and posttraumatic stress disorder. Journal of Clinical Psychiatry, 61(Suppl 7), 22–32. PubMed

Broese, M., Riemann, D., Hein, L., & Nissen, C. (2012). Alpha-Adrenergic receptor function, arousal and sleep: Mechanisms and therapeutic implications. Pharmacopsychiatry, 45(6), 209–216. https://doi.org/10.1055/s-0031-1299728. CrossRefPubMed

Brown, T. H., Mellman, T. A., Alfano, C. A., & Weems, C. F. (2011). Sleep fears, sleep disturbance, and PTSD symptoms in minority youth exposed to Hurricane Katrina. Journal of Traumatic Stress, 24(5), 575–580. https://doi.org/10.1002/jts.20680. CrossRefPubMed

Colvonen, P. J., Straus, L. D., Acheson, D., & Gehrman, P. (2019). A review of the relationship between emotional learning and memory, sleep, and PTSD. Current Psychiatry Reports, 21(1), 2. https://doi.org/10.1007/s11920-019-0987-2. CrossRefPubMedPubMedCentral

De Boer, M., Nijdam, M. J., Jongedijk, R. A., Bangel, K. A., Olff, M., Hofman, W. F., et al. (2020). The spectral fingerprint of sleep problems in post-traumatic stress disorder. Sleep, 43(4). https://doi.org/10.1093/sleep/zsz269.

De Jong, J., & Vermetten, E. (2018). Medication for sleep problems in posttraumatic stress disorder. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 325–348). New York, NY: Springer, New York. CrossRef

De Quervain, D., Wolf, O. T., & Roozendaal, B. (2019). Glucocorticoid-induced enhancement of extinction-from animal models to clinical trials. Psychopharmacology (Berl), 236(1), 183–199. https://doi.org/10.1007/s00213-018-5116-0. CrossRef

Dowd, S. M., Zalta, A. K., Burgess, H. J., Adkins, E. C., Valdespino-Hayden, Z., & Pollack, M. H. (2020). Double-blind randomized controlled study of the efficacy, safety and tolerability of eszopiclone vs placebo for the treatment of patients with post-traumatic stress disorder and insomnia. World Journal of Psychiatry, 10(3), 21. CrossRef

DSM-5 (2017). Beknopt overzicht van de criteria DSM-5. Nederlandse vertaling van Desk reference to the diagnostic criteria from DSM-5. Amsterdam: American Psychiatric Association|Boom uitgevers.

Duckers, M. L. A., & Olff, M. (2017). Does the vulnerability paradox in PTSD apply to women and men? An exploratory study. Journal of Traumatic Stress, 30(2), 200–204. https://doi.org/10.1002/jts.22173. CrossRefPubMed

Dunlop, B. W., & Wong, A. (2019). The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions. Progress in Neuropsychopharmacology and Biological Psychiatry, 89, 361–379. https://doi.org/10.1016/j.pnpbp.2018.10.010. CrossRef

Francati, V., Vermetten, E., & Bremner, J. D. (2007). Functional neuroimaging studies in posttraumatic stress disorder: Review of current methods and findings. Depression and Anxiety, 24(3), 202–218. https://doi.org/10.1002/da.20208. CrossRefPubMedPubMedCentral

Gallegos, A. M., Crean, H. F., Pigeon, W. R., & Heffner, K. L. (2017). Meditation and yoga for posttraumatic stress disorder: A meta-analytic review of randomized controlled trials. Clinical Psychology Review, 58, 115–124. CrossRef

Germain, A. (2013). Sleep disturbances as the hallmark of PTSD: where are we now? American Journal of Psychiatry, 170(4), 372–382. https://doi.org/10.1176/appi.ajp.2012.12040432. CrossRefPubMed

Germain, A., Campbell, R., & McKeon, A. (2018). Sleep disturbances and sleep assessment methods in PTSD. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 193–200). New York, NY: Springer, New York. CrossRef

Germain, A., Hall, M., Krakow, B., Shear, M., & Buysse, D. J. (2005). A brief sleep scale for posttraumatic stress disorder: Pittsburgh sleep quality index addendum for PTSD. Journal of Anxiety Disorders, 19(2), 233–244. https://doi.org/10.1016/j.janxdis.2004.02.001. CrossRefPubMed

Guina, J., Rossetter, S. R., DeRhodes, B. J., Nahhas, R. W., & Welton, R. S. (2015). Benzodiazepines for PTSD: A systematic review and meta-analysis. Journal of Psychiatric Practice®, 21(4), 281–303.

Insana, S. P., Hall, M., Buysse, D. J., & Germain, A. (2013). Validation of the Pittsburgh sleep quality index addendum for posttraumatic stress disorder (PSQI-A) in U.S. male military veterans. Journal of Traumatic Stress, 26(2), 192–200. https://doi.org/10.1002/jts.21793.

Iyadurai, L., Blackwell, S. E., Meiser-Stedman, R., Watson, P. C., Bonsall, M. B., Geddes, J. R., et al. (2018). Preventing intrusive memories after trauma via a brief intervention involving Tetris computer game play in the emergency department: A proof-of-concept randomized controlled trial. Molecular Psychiatry, 23(3), 674–682. https://doi.org/10.1038/mp.2017.23. CrossRefPubMed

Jetly, R., Heber, A., Fraser, G., & Boisvert, D. (2015). The efficacy of nabilone, a synthetic cannabinoid, in the treatment of PTSD-associated nightmares: A preliminary randomized, double-blind, placebo-controlled cross-over design study. Psychoneuroendocrinology, 51, 585–588. CrossRef

Kerkhof, G. A., Geuke, M. E., Brouwer, A., Rijsman, R. M., Schimsheimer, R. J., & Van Kasteel, V. (2013). Holland sleep disorders questionnaire: A new sleep disorders questionnaire based on the International Classification of Sleep Disorders-2. Journal of Sleep Research, 22(1), 104–107. https://doi.org/10.1111/j.1365-2869.2012.01041.x. CrossRefPubMed

Kessler, R. C., Aguilar-Gaxiola, S., Alonso, J., Benjet, C., Bromet, E. J., Cardoso, G., et al. (2017). Trauma and PTSD in the WHO world mental health surveys. European Journal of Psychotraumatology, 8(Suppl 5), 1353383. https://doi.org/10.1080/20008198.2017.1353383. CrossRefPubMedPubMedCentral

Khazaie, H., Ghadami, M. R., & Masoudi, M. (2016). Sleep disturbances in veterans with chronic war-induced PTSD. Journal of Injury and Violence Research, 8(2), 99–107. https://doi.org/10.5249/jivr.v8i2.808. CrossRefPubMedPubMedCentral

Klein, E., Koren, D., Arnon, I., & Lavie, P. (2002). No evidence of sleep disturbance in post-traumatic stress disorder: A polysomnographic study in injured victims of traffic accidents. Israel Journal of Psychiatry and Related Sciences, 39(1), 3–10. PubMed

Koffel, E., Khawaja, I. S., & Germain, A. (2016). Sleep disturbances in posttraumatic stress disorder: Updated review and implications for treatment. Psychiatric Annals, 46(3), 173–176. https://doi.org/10.3928/00485713-20160125-01. CrossRefPubMedPubMedCentral

Koren, D., Arnon, I., Lavie, P., & Klein, E. (2002). Sleep complaints as early predictors of posttraumatic stress disorder: A 1-year prospective study of injured survivors of motor vehicle accidents. American Journal of Psychiatry, 159(5), 855–857. https://doi.org/10.1176/appi.ajp.159.5.855. CrossRefPubMed

Krakow, B., Moore, B., & Ulibarri, V. A. (2018). Sleep-disordered breathing and posttraumatic stress disorder. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 243–252). New York, NY: Springer, New York. CrossRef

Krediet, E., Bostoen, T., Breeksema, J., Van Schagen, A., Passie, T., & Vermetten, E. (2020). Reviewing the potential of psychedelics for the treatment of PTSD. International Journal of Neuropsychopharmacology. https://doi.org/10.1093/ijnp/pyaa018. CrossRefPubMedCentral

Lavie, P. (2001). Sleep disturbances in the wake of traumatic events. New England Journal of Medicine, 345(25), 1825–1832. https://doi.org/10.1056/NEJMra012893. CrossRefPubMed

Lewis, C., Roberts, N. P., Andrew, M., Starling, E., & Bisson, J. I. (2020). Psychological therapies for post-traumatic stress disorder in adults: Systematic review and meta-analysis. European Journal of Psychotraumatology, 11(1), 1729633. https://doi.org/10.1080/20008198.2020.1729633. CrossRefPubMedPubMedCentral

López, H. H., Bracha, A. S., & Bracha, H. S. (2002). Evidence based complementary intervention for insomnia. Hawaii Medical Journal, 61(9), 192, 213.

Mellman, T. A., Kumar, A., Kulick-Bell, R., Kumar, M., & Nolan, B. (1995). Nocturnal/daytime urine noradrenergic measures and sleep in combat-related PTSD. Biological Psychiatry, 38(3), 174–179. https://doi.org/10.1016/0006-3223(94)00238-x. CrossRefPubMed

Miller, K. E., Brownlow, J. A., & Gehrman, P. R. (2020). Sleep in PTSD: Treatment approaches and outcomes. Current Opinion in Psychology, 34, 12–17. https://doi.org/10.1016/j.copsyc.2019.08.017. CrossRefPubMed

Miller, K. E., Brownlow, J. A., Woodward, S., & Gehrman, P. R. (2017). Sleep and dreaming in posttraumatic stress disorder. Current Psychiatry Reports, 19(10), 71. https://doi.org/10.1007/s11920-017-0827-1. CrossRefPubMed

Morgenthaler, T. I., Auerbach, S., Casey, K. R., Kristo, D., Maganti, R., Ramar, K., et al. (2018). Position paper for the treatment of nightmare disorder in adults: An American Academy of sleep medicine position paper. Journal of Clinical Sleep Medicine, 14(6), 1041–1055. https://doi.org/10.5664/jcsm.7178. CrossRefPubMedPubMedCentral

Mysliwiec, V., Brock, M. S., Thomas, A. L., & Creamer, J. L. (2018). The extreme nocturnal manifestation of trauma: Trauma associated sleep disorder. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 215–225). New York, NY: Springer, New York. CrossRef

Nardo, D., Hogberg, G., Jonsson, C., Jacobsson, H., Hallstrom, T., & Pagani, M. (2015). Neurobiology of sleep disturbances in PTSD patients and traumatized controls: MRI and SPECT findings. Frontiers in Psychiatry, 6, 134. https://doi.org/10.3389/fpsyt.2015.00134. CrossRefPubMedPubMedCentral

Neylan, T. C., Marmar, C. R., Metzler, T. J., Weiss, D. S., Zatzick, D. F., Delucchi, K. L., et al. (1998). Sleep disturbances in the Vietnam generation: Findings from a nationally representative sample of male Vietnam veterans. American Journal of Psychiatry, 155(7), 929–933. CrossRef

Nijdam, M. J., & Vermetten, E. (2018). Moving forward in treatment of posttraumatic stress disorder: Innovations to exposure-based therapy. European Journal of Psychotraumatology, 9(1), 1458568. https://doi.org/10.1080/20008198.2018.1458568. CrossRefPubMedPubMedCentral

Noll, J. G., Trickett, P. K., Susman, E. J., & Putnam, F. W. (2006). Sleep disturbances and childhood sexual abuse. Journal of Pediatric Psychology, 31(5), 469–480. https://doi.org/10.1093/jpepsy/jsj040.

Ohayon, M. M., & Shapiro, C. M. (2000). Sleep disturbances and psychiatric disorders associated with posttraumatic stress disorder in the general population. Comprehensive Psychiatry, 41(6), 469–478. https://doi.org/10.1053/comp.2000.16568. CrossRefPubMed

Raskind, M. A., Peskind, E. R., Chow, B., Harris, C., Davis-Karim, A., Holmes, H. A., et al. (2018). Trial of prazosin for post-traumatic stress disorder in military veterans. New England Journal of Medicine, 378(6), 507–517. CrossRef

Repantis, D., Wermuth, K., Tsamitros, N., Danker-Hopfe, H., Bublitz, J. C., Kühn, S., et al. (2020). REM sleep in acutely traumatized individuals and interventions for the secondary prevention of post-traumatic stress disorder. European Journal of Psychotraumatology, 11(1), 1740492. https://doi.org/10.1080/20008198.2020.1740492. CrossRefPubMedPubMedCentral

Richards, A., Inslicht, S., Ruoff, L. M., Metzler, T. J., Goldstein, L. A., Chapman, C. M., et al. (2018). An open-label study of doxazosin extended-release for PTSD: Findings and recommendations for future research on doxazosin. Focus, 16(1), 67–73. CrossRef

Richards, A., Kanady, J. C., & Neylan, T. C. (2020). Sleep disturbance in PTSD and other anxiety-related disorders: An updated review of clinical features, physiological characteristics, and psychological and neurobiological mechanisms. Neuropsychopharmacology, 45(1), 55–73. https://doi.org/10.1038/s41386-019-0486-5. CrossRefPubMed

Rizzo, A., Roy, M. J., Hartholt, A., Costanzo, M., Highland, K. B., Jovanovic, T., et al. (2017). Virtual reality applications for the assessment and treatment of PTSD. In S. V. Bowles & P. T. Bartone (Eds.), Handbook of military psychology: Clinical and organizational practice (pp. 453–471). Cham: Springer International Publishing. CrossRef

Rothbaum, B. O., Price, M., Jovanovic, T., Norrholm, S. D., Gerardi, M., Dunlop, B., et al. (2014). A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans. American Journal of Psychiatry, 171(6), 640–648. CrossRef

Schnyder, U., Ehlers, A., Elbert, T., Foa, E. B., Gersons, B. P., Resick, P. A., et al. (2015). Psychotherapies for PTSD: What do they have in common? European Journal of Psychotraumatology, 6, 28186. https://doi.org/10.3402/ejpt.v6.28186. CrossRefPubMed

Schreuder, B. J., Kleijn, W. C., & Rooijmans, H. G. (2000). Nocturnal re-experiencing more than forty years after war trauma. Journal of Traumatic Stress, 13(3), 453–463. https://doi.org/10.1023/a:1007733324351. CrossRefPubMed

Shannon, M. P., Lonigan, C. J., Finch, A. J., Jr., & Taylor, C. M. (1994). Children exposed to disaster: I. Epidemiology of post-traumatic symptoms and symptom profiles. Journal of the American Academy of Child and Adolescent Psychiatry, 33(1), 80–93. https://doi.org/10.1097/00004583-199401000-00012.

Sharon, A., Levav, I., Brodsky, J., Shemesh, A. A., & Kohn, R. (2009). Psychiatric disorders and other health dimensions among Holocaust survivors 6 decades later. British Journal of Psychiatry, 195(4), 331–335. https://doi.org/10.1192/bjp.bp.108.058784. CrossRef

Smid, G. E., Mooren, T. T., Van der Mast, R. C., Gersons, B. P., & Kleber, R. J. (2009). Delayed posttraumatic stress disorder: systematic review, meta-analysis, and meta-regression analysis of prospective studies. Journal of Clinical Psychiatry, 70(11), 1572–1582. https://doi.org/10.4088/JCP.08r04484. CrossRefPubMed

Solomonova, E. (2018). Sleep paralysis: Phenomenology, neurophysiology, and treatment. In K. Christoff & K. C. R. Fox (Eds.), The Oxford handbook of spontaneous thought: Mind-wandering, creativity, and dreaming. Oxford: Oxford University Press.

Spangler, P. T., & West, J. C. (2018). Nightmare deconstruction and reprocessing for PTSD nightmares. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 311–316). New York, NY: Springer, New York. CrossRef

Spoormaker, V. I. (2018). PTSD, arousal, and disrupted (REM) sleep. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 227–232). New York, NY: Springer, New York. CrossRef

Szigethy, E., & Vermetten, E. (2018). Hypnotic interventions for sleep in PTSD. In E. Vermetten, A. Germain, & T. C. Neylan (Eds.), Sleep and combat-related post traumatic stress disorder (pp. 317–324). New York, NY: Springer, New York. CrossRef

Tsanas, A., Woodward, E., & Ehlers, A. (2020). Objective characterization of activity, sleep, and circadian rhythm patterns using a wrist-worn actigraphy sensor: Insights into posttraumatic stress disorder. JMIR Mhealth Uhealth, 8(4), e14306. https://doi.org/10.2196/14306. CrossRefPubMedPubMedCentral

Ullah, M. I., Campbell, D. G., Bhagat, R., Lyons, J. A., & Tamanna, S. (2017). Improving PTSD symptoms and preventing progression of subclinical PTSD to an overt disorder by treating comorbid OSA with CPAP. Journal of Clinical Sleep Medicine, 13(10), 1191–1198. https://doi.org/10.5664/jcsm.6770. CrossRefPubMedPubMedCentral

Van der Helm, E., Yao, J., Dutt, S., Rao, V., Saletin, J. M., & Walker, M. P. (2011). REM sleep depotentiates amygdala activity to previous emotional experiences. Current Biology, 21(23), 2029–2032. https://doi.org/10.1016/j.cub.2011.10.052. CrossRefPubMed

Van Liempt, S. (2012). Sleep disturbances and PTSD: A perpetual circle? European Journal of Psychotraumatology, 3(Supp3), 19142. CrossRef

Van Liempt, S., Arends, J., Cluitmans, P. J., Westenberg, H. G., Kahn, R. S., & Vermetten, E. (2013). Sympathetic activity and hypothalamo-pituitary-adrenal axis activity during sleep in post-traumatic stress disorder: A study assessing polysomnography with simultaneous blood sampling. Psychoneuroendocrinology, 38(1), 155–165. https://doi.org/10.1016/j.psyneuen.2012.05.015. CrossRefPubMed

Vandrey, R., Babson, K. A., Herrmann, E. S., & Bonn-Miller, M. O. (2014). Interactions between disordered sleep, post-traumatic stress disorder, and substance use disorders. International Review of Psychiatry, 26(2), 237–247. https://doi.org/10.3109/09540261.2014.901300. CrossRefPubMed

Vermetten, E., & Bremner, J. D. (2002). Circuits and systems in stress. I. Preclinical studies. Depress Anxiety, 15(3), 126–147. https://doi.org/10.1002/da.10016. CrossRefPubMed

Vermetten, E., Dorahy, M. J., & Spiegel, D. (Eds.). (2007). Traumatic dissociation: Neurobiology and treatment. Washington, DC: American Psychiatric Publishing.

Vermetten, E., Germain, A., & Neylan, T. C. (Eds.). (2018). Sleep and combat-related post traumatic stress disorder (1st ed.). New York, NY: Springer.

Vermetten, E., Stein, D. J., & McFarlane, A. C. (2016). Is there a vulnerability paradox in PTSD? Pitfalls in cross-national comparisons of epidemiological data. British Journal of Psychiatry, 209(6), 527. https://doi.org/10.1192/bjp.209.6.527. CrossRef

Wallace, D. M., Shafazand, S., Ramos, A. R., Carvalho, D. Z., Gardener, H., Lorenzo, D., et al. (2011). Insomnia characteristics and clinical correlates in operation enduring freedom/operation Iraqi freedom veterans with post-traumatic stress disorder and mild traumatic brain injury: An exploratory study. Sleep Medicine, 12(9), 850–859. https://doi.org/10.1016/j.sleep.2011.06.004. CrossRefPubMed

Wallace, M. L., Iyengar, S., Bramoweth, A. D., Frank, E., & Germain, A. (2015). Clarifying heterogeneity of daytime and nighttime symptoms of post-traumatic stress in combat veterans with insomnia. Military Psychology, 27(4), 212–222. https://doi.org/10.1037/mil0000077. CrossRefPubMedPubMedCentral

Weathers, F. W., Litz, B. T., Keane, T. M., Palmieri, P. A., Marx, B. P., & Schnurr, P. P. (2013). The PTSD Checklist for DSM-5 (PCL-5). https://www.psychotraumadiagnostics.centrum45.nl/nl/ptss.

Woon, F. L., Sood, S., & Hedges, D. W. (2010). Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: A meta-analysis. Progress in Neuropsychopharmacology and Biological Psychiatry, 34(7), 1181–1188. https://doi.org/10.1016/j.pnpbp.2010.06.016. CrossRef

Yücel, D. E., Van Emmerik, A. A., Souama, C., & Lancee, J. (2019). Comparative efficacy of imagery rehearsal therapy and prazosin in the treatment of trauma-related nightmares in adults: A meta-analysis of randomized controlled trials. Sleep Medicine Reviews, 101248.

Zhang, Y., Ren, R., Sanford, L. D., Yang, L., Ni, Y., Zhou, J., et al. (2020). The effects of prazosin on sleep disturbances in post-traumatic stress disorder: A systematic review and meta-analysis. Sleep Medicine, 67, 225–231. https://doi.org/10.1016/j.sleep.2019.06.010. CrossRefPubMed

Titel: Posttraumatische stressstoornis
Auteurs: dr. Annette van Schagen
prof. dr. Eric Vermetten
Uitgeverij: Bohn Stafleu van Loghum
Boek: Slaapstoornissen in de psychiatrie
Print ISBN: 978-90-368-2523-8

Elektronisch ISBN: 978-90-368-2524-5

Copyright: 2021
DOI: https://doi.org/10.1007/978-90-368-2524-5_13

Bohn Stafleu van Loghum

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