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Gepubliceerd in: Child Psychiatry & Human Development 6/2010

01-12-2010 | Review Paper

Posttraumatic Stress Disorder in Children and Adolescents: A Review of Psychopharmacological Treatment

Auteurs: J. Huemer, F. Erhart, H. Steiner

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 6/2010

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Abstract

PTSD in children and adolescents differs from the adult disease. Therapeutic approaches involve both psychotherapy and psychopharmacotherapy. Objectives: The current paper aims at reviewing studies on psychopharmacological treatment of childhood and adolescent PTSD. Additionally, developmental frameworks for PTSD diagnosis and research along with an experimental model of quenching and kindling in the context of stress exposure are presented. We conducted an extensive literature search of reviews on psychopharmacotherapy as well as studies on psychopharmacological treatment for PTSD among children and adolescents. We used the database PubMed and focused on the time period of the last 10 years up to January 2009. Pertinent earlier papers were also included.There are a limited number of studies specifically assessing the psychopharmacological treatment of PTSD in children and adolescents. The vast majority of them lack verification in RCTs. Only the use of imipramine, divalproex sodium and sertraline were already evaluated in RCTs. Future studies should take into account developmental approaches to the diagnosis and treatment of PTSD in children and adolescents. In this context, different underlying neurobiological patterns, which are reflected in distinct clinical symptomatology, require a precise investigation and a symptom-orientated psychopharmacological approach.
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Metagegevens
Titel
Posttraumatic Stress Disorder in Children and Adolescents: A Review of Psychopharmacological Treatment
Auteurs
J. Huemer
F. Erhart
H. Steiner
Publicatiedatum
01-12-2010
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 6/2010
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-010-0192-3

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