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01-03-2009 | Original Paper | Uitgave 3/2009

Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 3/2009

Auteurs:: Laudan B. Jahromi, Connie L. Kasari, James T. McCracken, Lisa S-Y. Lee, Michael G. Aman, Christopher J. McDougle, Lawrence Scahill, Elaine Tierney, L. Eugene Arnold, Benedetto Vitiello, Louise Ritz, Andrea Witwer, Erin Kustan, Jaswinder Ghuman, David J. Posey

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Abstract

This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data. Participants were 33 children (29 boys) between the ages of 5 and 13 years who participated in a four-week crossover trial of placebo and increasing doses of methylphenidate given in random order each for one week. Observational measures of certain aspects of children’s social communication, self-regulation, and affective behavior were obtained each week. A significant positive effect of methylphenidate was seen on children’s use of joint attention initiations, response to bids for joint attention, self-regulation, and regulated affective state. The results go beyond the recent literature and suggest that methylphenidate may have positive effects on social behaviors in children with PDD and hyperactivity.

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Titel: Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity
Auteurs:: Laudan B. Jahromi
Connie L. Kasari
James T. McCracken
Lisa S-Y. Lee
Michael G. Aman
Christopher J. McDougle
Lawrence Scahill
Elaine Tierney
L. Eugene Arnold
Benedetto Vitiello
Louise Ritz
Andrea Witwer
Erin Kustan
Jaswinder Ghuman
David J. Posey
Publicatiedatum: 01-03-2009
DOI: https://doi.org/10.1007/s10803-008-0636-9
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 3/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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