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Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2009

01-03-2009 | Original Paper

Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity

Auteurs: Laudan B. Jahromi, Connie L. Kasari, James T. McCracken, Lisa S-Y. Lee, Michael G. Aman, Christopher J. McDougle, Lawrence Scahill, Elaine Tierney, L. Eugene Arnold, Benedetto Vitiello, Louise Ritz, Andrea Witwer, Erin Kustan, Jaswinder Ghuman, David J. Posey

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2009

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Abstract

This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data. Participants were 33 children (29 boys) between the ages of 5 and 13 years who participated in a four-week crossover trial of placebo and increasing doses of methylphenidate given in random order each for one week. Observational measures of certain aspects of children’s social communication, self-regulation, and affective behavior were obtained each week. A significant positive effect of methylphenidate was seen on children’s use of joint attention initiations, response to bids for joint attention, self-regulation, and regulated affective state. The results go beyond the recent literature and suggest that methylphenidate may have positive effects on social behaviors in children with PDD and hyperactivity.
Literatuur
go back to reference Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985a). The Aberrant Behavior Checklist: A behavior rating scale of the assessment of treatment effects. American Journal of Mental Deficiency, 89, 485–491. PubMed Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985a). The Aberrant Behavior Checklist: A behavior rating scale of the assessment of treatment effects. American Journal of Mental Deficiency, 89, 485–491. PubMed
go back to reference Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985b). Psychometric characteristics of the Aberrant Behavior Checklist. American Journal of Mental Deficiency, 49, 492–502. Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985b). Psychometric characteristics of the Aberrant Behavior Checklist. American Journal of Mental Deficiency, 49, 492–502.
go back to reference Diener, M. L., & Mangelsdorf, S. C. (1999). Behavioral strategies for emotion regulation in toddlers: Associations with maternal involvement and emotional expressions. Infant Behavior and Development, 22, 569–583. doi: 10.​1016/​S0163-6383(00)00012-6. CrossRef Diener, M. L., & Mangelsdorf, S. C. (1999). Behavioral strategies for emotion regulation in toddlers: Associations with maternal involvement and emotional expressions. Infant Behavior and Development, 22, 569–583. doi: 10.​1016/​S0163-6383(00)00012-6. CrossRef
go back to reference Diener, M. L., Mangelsdorf, S. C., McHale, J. L., & Frosch, C. A. (2002). Infants’ behavioral strategies for emotion regulation with fathers and mothers: Associations with emotional expressions and attachment quality. Infancy, 3, 153–174. doi: 10.​1207/​S15327078IN0302_​3. CrossRef Diener, M. L., Mangelsdorf, S. C., McHale, J. L., & Frosch, C. A. (2002). Infants’ behavioral strategies for emotion regulation with fathers and mothers: Associations with emotional expressions and attachment quality. Infancy, 3, 153–174. doi: 10.​1207/​S15327078IN0302_​3. CrossRef
go back to reference Eisenberg, N., Fabes, R., Murphy, B., Maszk, P., Smith, M., & Karbon, M. (1995). The role of emotionality and regulation in children’s social functioning: A longitudinal study. Child Development, 66, 1360–1384. doi: 10.​2307/​1131652. PubMedCrossRef Eisenberg, N., Fabes, R., Murphy, B., Maszk, P., Smith, M., & Karbon, M. (1995). The role of emotionality and regulation in children’s social functioning: A longitudinal study. Child Development, 66, 1360–1384. doi: 10.​2307/​1131652. PubMedCrossRef
go back to reference Handen, B. L., Johnson, C. R., & Lubetsky, M. (2000). Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. Journal of Autism and Developmental Disorders, 30, 245–255. doi: 10.​1023/​A:​1005548619694. PubMedCrossRef Handen, B. L., Johnson, C. R., & Lubetsky, M. (2000). Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. Journal of Autism and Developmental Disorders, 30, 245–255. doi: 10.​1023/​A:​1005548619694. PubMedCrossRef
go back to reference Jahromi, L. B., & Stifter, C. A. (2008). Individual differences in preschoolers’ self-regulation and theory of mind. Merrill-Palmer Quarterly, 54, 125–150. CrossRef Jahromi, L. B., & Stifter, C. A. (2008). Individual differences in preschoolers’ self-regulation and theory of mind. Merrill-Palmer Quarterly, 54, 125–150. CrossRef
go back to reference Kasari, C., Freeman, S., Paparella, T., & Jahromi, L. B. (2008). Predicting language outcome in autism from controlled comparison of joint attention and play interventions. Journal of Clinical and Consulting Psychology, 76, 125–137. CrossRef Kasari, C., Freeman, S., Paparella, T., & Jahromi, L. B. (2008). Predicting language outcome in autism from controlled comparison of joint attention and play interventions. Journal of Clinical and Consulting Psychology, 76, 125–137. CrossRef
go back to reference Lecavalier, L. (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36, 1101–1114. doi: 10.​1007/​s10803-006-0147-5. PubMedCrossRef Lecavalier, L. (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36, 1101–1114. doi: 10.​1007/​s10803-006-0147-5. PubMedCrossRef
go back to reference Loveland, K. A. (2005). Social-emotional impairment and self-regulation in autism spectrum disorder. In J. Nadel & D. Muir (Eds.), Emotional development: Recent research advance (pp. 365–382). New York: Oxford University Press. Loveland, K. A. (2005). Social-emotional impairment and self-regulation in autism spectrum disorder. In J. Nadel & D. Muir (Eds.), Emotional development: Recent research advance (pp. 365–382). New York: Oxford University Press.
go back to reference Morales, M., Mundy, P., Crowson, M. M., Neal, A. R., & Delgado, C. E. F. (2005). Individual differences in infant attention skills, joint attention, and emotion regulation behaviour. International Journal of Behavioral Development, 29, 259–263. Morales, M., Mundy, P., Crowson, M. M., Neal, A. R., & Delgado, C. E. F. (2005). Individual differences in infant attention skills, joint attention, and emotion regulation behaviour. International Journal of Behavioral Development, 29, 259–263.
go back to reference Mundy, P., & Acra, F. (2006). Joint attention, social engagement and the development of social competence. In P. Marshall & N. Fox (Eds.), The development of social engagement neurobiological perspectives (pp. 81–117). New York: Oxford University Press. Mundy, P., & Acra, F. (2006). Joint attention, social engagement and the development of social competence. In P. Marshall & N. Fox (Eds.), The development of social engagement neurobiological perspectives (pp. 81–117). New York: Oxford University Press.
go back to reference Mundy, P., Delgado, C., Block, J., Venezia, M., Hogan, A., & Seibert, J. (2003). A manual for the abridged Early Social Communication Scales (ESCS), Coral Gables. FL: University of Miami. Mundy, P., Delgado, C., Block, J., Venezia, M., Hogan, A., & Seibert, J. (2003). A manual for the abridged Early Social Communication Scales (ESCS), Coral Gables. FL: University of Miami.
go back to reference Mundy, P., Sigman, M., & Kasari, C. (1990). A longitudinal study of joint attention and language development in autistic children. Journal of Autism and Developmental Disorders, 20, 115–128. doi: 10.​1007/​BF02206861. PubMedCrossRef Mundy, P., Sigman, M., & Kasari, C. (1990). A longitudinal study of joint attention and language development in autistic children. Journal of Autism and Developmental Disorders, 20, 115–128. doi: 10.​1007/​BF02206861. PubMedCrossRef
go back to reference Pearson, D. A., Lane, D. M., Santos, C. W., Casat, C. D., Jerger, S. W., Loveland, K. A., et al. (2004). Effects of methylphenidate treatment in children with mental retardation and ADHD: Individual variation in medication response. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 686–698. doi: 10.​1097/​01.​chi.​0000120024.​14101.​96. PubMedCrossRef Pearson, D. A., Lane, D. M., Santos, C. W., Casat, C. D., Jerger, S. W., Loveland, K. A., et al. (2004). Effects of methylphenidate treatment in children with mental retardation and ADHD: Individual variation in medication response. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 686–698. doi: 10.​1097/​01.​chi.​0000120024.​14101.​96. PubMedCrossRef
go back to reference Quintana, H., Birmaher, B., Stedge, D., Lennon, S., Freed, J., Bridge, J., et al. (1995). Use of methylphenidate in treatment of children with autistic disorder. Journal of Autism and Developmental Disorders, 25, 283–295. doi: 10.​1007/​BF02179289. PubMedCrossRef Quintana, H., Birmaher, B., Stedge, D., Lennon, S., Freed, J., Bridge, J., et al. (1995). Use of methylphenidate in treatment of children with autistic disorder. Journal of Autism and Developmental Disorders, 25, 283–295. doi: 10.​1007/​BF02179289. PubMedCrossRef
go back to reference Research Units on Pediatric Psychopharmacology Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. The New England Journal of Medicine, 347, 314–321. doi: 10.​1056/​NEJMoa013171. CrossRef Research Units on Pediatric Psychopharmacology Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. The New England Journal of Medicine, 347, 314–321. doi: 10.​1056/​NEJMoa013171. CrossRef
go back to reference Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005). Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62, 1266–1274. doi: 10.​1001/​archpsyc.​62.​11.​1266. CrossRef Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005). Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62, 1266–1274. doi: 10.​1001/​archpsyc.​62.​11.​1266. CrossRef
go back to reference Roid, G. H., & Miller, L. J. (1995). Leiter international performance scale-revised. Wood Dale, IL: Stoelting. Roid, G. H., & Miller, L. J. (1995). Leiter international performance scale-revised. Wood Dale, IL: Stoelting.
go back to reference Rothbart, M., Posner, M., & Boylan, A. (1990). Regulatory mechanisms in infant development. In J. Enns (Ed.), The development of attention: Research and theory. Holland: Elsevier. Rothbart, M., Posner, M., & Boylan, A. (1990). Regulatory mechanisms in infant development. In J. Enns (Ed.), The development of attention: Research and theory. Holland: Elsevier.
go back to reference Slosson, R. L. (1983). Slosson intelligence test. East Aurora, NY: Slosson Educational Publications. Slosson, R. L. (1983). Slosson intelligence test. East Aurora, NY: Slosson Educational Publications.
go back to reference Stigler, K. A., Desomond, L. A., Posey, D. J., Wiegand, R. E., & McDougle, C. J. (2004). A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 14, 49–56. doi: 10.​1089/​1044546047738404​81. PubMedCrossRef Stigler, K. A., Desomond, L. A., Posey, D. J., Wiegand, R. E., & McDougle, C. J. (2004). A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 14, 49–56. doi: 10.​1089/​1044546047738404​81. PubMedCrossRef
go back to reference Thompson, R. (1994). Emotion regulation: A theme in search of definition. Monographs of the Society for Research in Child Development, 59(2–3, Serial No. 240), 25–52. Thompson, R. (1994). Emotion regulation: A theme in search of definition. Monographs of the Society for Research in Child Development, 59(2–3, Serial No. 240), 25–52.
go back to reference Wetherby, A. M., Prizant, B. M., & Schuler, A. L. (2000). Understanding the nature of communication and language impairments. In A. M. Wetherby & B. M. Prizant (Eds.), Autism spectrum disorders: A transactional developmental perspective (pp. 109–141). Baltimore, MD: Paul H. Brookes. Wetherby, A. M., Prizant, B. M., & Schuler, A. L. (2000). Understanding the nature of communication and language impairments. In A. M. Wetherby & B. M. Prizant (Eds.), Autism spectrum disorders: A transactional developmental perspective (pp. 109–141). Baltimore, MD: Paul H. Brookes.
Metagegevens
Titel
Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity
Auteurs
Laudan B. Jahromi
Connie L. Kasari
James T. McCracken
Lisa S-Y. Lee
Michael G. Aman
Christopher J. McDougle
Lawrence Scahill
Elaine Tierney
L. Eugene Arnold
Benedetto Vitiello
Louise Ritz
Andrea Witwer
Erin Kustan
Jaswinder Ghuman
David J. Posey
Publicatiedatum
01-03-2009
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0636-9

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