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Gepubliceerd in:

01-03-2009 | Original Paper

Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity

Auteurs: Laudan B. Jahromi, Connie L. Kasari, James T. McCracken, Lisa S-Y. Lee, Michael G. Aman, Christopher J. McDougle, Lawrence Scahill, Elaine Tierney, L. Eugene Arnold, Benedetto Vitiello, Louise Ritz, Andrea Witwer, Erin Kustan, Jaswinder Ghuman, David J. Posey

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2009

Abstract

This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data. Participants were 33 children (29 boys) between the ages of 5 and 13 years who participated in a four-week crossover trial of placebo and increasing doses of methylphenidate given in random order each for one week. Observational measures of certain aspects of children’s social communication, self-regulation, and affective behavior were obtained each week. A significant positive effect of methylphenidate was seen on children’s use of joint attention initiations, response to bids for joint attention, self-regulation, and regulated affective state. The results go beyond the recent literature and suggest that methylphenidate may have positive effects on social behaviors in children with PDD and hyperactivity.

volgende artikel Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders

Aman, M. G. (1996). Stimulant drugs in the developmental disabilities revisited. Journal of Developmental and Physical Disabilities, 8, 347–365. doi: 10.1007/BF02578400. CrossRef

Aman, M. G., & Langworthy, K. S. (2000). Pharmacotherapy for hyperactivity in children with autism and other pervasive developmental disorders. Journal of Autism and Developmental Disorders, 30, 451–459. doi: 10.1023/A:1005559725475. PubMedCrossRef

Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985a). The Aberrant Behavior Checklist: A behavior rating scale of the assessment of treatment effects. American Journal of Mental Deficiency, 89, 485–491. PubMed

Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985b). Psychometric characteristics of the Aberrant Behavior Checklist. American Journal of Mental Deficiency, 49, 492–502.

Bakeman, R., & Adamson, L. B. (1984). Coordinating attention to people and objects in mother-infant and peer-infant interaction. Child Development, 55, 1278–1289. doi: 10.2307/1129997. PubMedCrossRef

Barkley, R. A. (1988). The effects of methylphenidate on interactions of preschool ADHD children with their mothers. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 336–341. doi: 10.1097/00004583-198805000-00012. PubMedCrossRef

Diener, M. L., & Mangelsdorf, S. C. (1999). Behavioral strategies for emotion regulation in toddlers: Associations with maternal involvement and emotional expressions. Infant Behavior and Development, 22, 569–583. doi: 10.1016/S0163-6383(00)00012-6. CrossRef

Diener, M. L., Mangelsdorf, S. C., McHale, J. L., & Frosch, C. A. (2002). Infants’ behavioral strategies for emotion regulation with fathers and mothers: Associations with emotional expressions and attachment quality. Infancy, 3, 153–174. doi: 10.1207/S15327078IN0302_3. CrossRef

Eisenberg, N., Fabes, R., Murphy, B., Maszk, P., Smith, M., & Karbon, M. (1995). The role of emotionality and regulation in children’s social functioning: A longitudinal study. Child Development, 66, 1360–1384. doi: 10.2307/1131652. PubMedCrossRef

Handen, B. L., Johnson, C. R., & Lubetsky, M. (2000). Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. Journal of Autism and Developmental Disorders, 30, 245–255. doi: 10.1023/A:1005548619694. PubMedCrossRef

Hazell, P. (2007). Drug therapy for attention-deficit/hyperactivity disorder-like symptoms in autistic disorder. Journal of Paediatrics and Child Health, 43, 19–24. doi: 10.1111/j.1440-1754.2007.00995.x. PubMedCrossRef

Howse, R. B., Calkins, S. D., Anastopoulos, A. D., Keane, S. P., & Shelton, T. L. (2003). Regulatory contributors to children’s kindergarten achievement. Early Education and Development, 14, 101–119. doi: 10.1207/s15566935eed1401_7. CrossRef

Jahromi, L. B., & Stifter, C. A. (2008). Individual differences in preschoolers’ self-regulation and theory of mind. Merrill-Palmer Quarterly, 54, 125–150. CrossRef

Kasari, C., Freeman, S., & Paparella, T. (2006). Joint attention and play in young children with autism: A randomized controlled intervention study. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 47, 611–620. doi: 10.1111/j.1469-7610.2005.01567.x. PubMedCrossRef

Kasari, C., Freeman, S., Paparella, T., & Jahromi, L. B. (2008). Predicting language outcome in autism from controlled comparison of joint attention and play interventions. Journal of Clinical and Consulting Psychology, 76, 125–137. CrossRef

Kochanska, G., Coy, K. C., & Murray, K. (2001). The development of self-regulation in the first four years of life. Child Development, 72, 1091–1111. doi: 10.1111/1467-8624.00336. PubMedCrossRef

Kopp, C. B. (1982). Antecedents of self-regulation: A developmental perspective. Developmental Psychology, 18, 199–214. doi: 10.1037/0012-1649.18.2.199. CrossRef

Kuczynski, L., & Kochanska, G. (1990). Development of children’s noncompliance strategies from toddlerhood to age 5. Developmental Psychology, 26, 398–408. doi: 10.1037/0012-1649.26.3.398. CrossRef

Lecavalier, L. (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36, 1101–1114. doi: 10.1007/s10803-006-0147-5. PubMedCrossRef

Loveland, K. A. (2005). Social-emotional impairment and self-regulation in autism spectrum disorder. In J. Nadel & D. Muir (Eds.), Emotional development: Recent research advance (pp. 365–382). New York: Oxford University Press.

Morales, M., Mundy, P., Crowson, M. M., Neal, A. R., & Delgado, C. E. F. (2005). Individual differences in infant attention skills, joint attention, and emotion regulation behaviour. International Journal of Behavioral Development, 29, 259–263.

Mundy, P., & Acra, F. (2006). Joint attention, social engagement and the development of social competence. In P. Marshall & N. Fox (Eds.), The development of social engagement neurobiological perspectives (pp. 81–117). New York: Oxford University Press.

Mundy, P., Delgado, C., Block, J., Venezia, M., Hogan, A., & Seibert, J. (2003). A manual for the abridged Early Social Communication Scales (ESCS), Coral Gables. FL: University of Miami.

Mundy, P., Sigman, M., & Kasari, C. (1990). A longitudinal study of joint attention and language development in autistic children. Journal of Autism and Developmental Disorders, 20, 115–128. doi: 10.1007/BF02206861. PubMedCrossRef

Mundy, P., Sigman, M., Ungerer, J., & Sherman, T. (1986). Defining the social deficits of autism: The contribution of non-verbal communication measures. Journal of Child Psychology, and Psychiatry and Allied Disciplines, 27, 657–669. doi: 10.1111/j.1469-7610.1986.tb00190.x. CrossRef

Pearson, D. A., Lane, D. M., Santos, C. W., Casat, C. D., Jerger, S. W., Loveland, K. A., et al. (2004). Effects of methylphenidate treatment in children with mental retardation and ADHD: Individual variation in medication response. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 686–698. doi: 10.1097/01.chi.0000120024.14101.96. PubMedCrossRef

Posey, D. J., Aman, M. G., McCracken, J. T., Scahill, L., Tierney, E., Arnold, L. E., et al. (2007). Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: An analysis of secondary measures. Biological Psychiatry, 61, 538–544. doi: 10.1016/j.biopsych.2006.09.028. PubMedCrossRef

Quintana, H., Birmaher, B., Stedge, D., Lennon, S., Freed, J., Bridge, J., et al. (1995). Use of methylphenidate in treatment of children with autistic disorder. Journal of Autism and Developmental Disorders, 25, 283–295. doi: 10.1007/BF02179289. PubMedCrossRef

Research Units on Pediatric Psychopharmacology Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. The New England Journal of Medicine, 347, 314–321. doi: 10.1056/NEJMoa013171. CrossRef

Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005). Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62, 1266–1274. doi: 10.1001/archpsyc.62.11.1266. CrossRef

Roid, G. H., & Miller, L. J. (1995). Leiter international performance scale-revised. Wood Dale, IL: Stoelting.

Rothbart, M., Posner, M., & Boylan, A. (1990). Regulatory mechanisms in infant development. In J. Enns (Ed.), The development of attention: Research and theory. Holland: Elsevier.

Scahill, L., McDougle, C. J., Williams, S. K., Dimitropoulos, A., Aman, M. G., McCracken, J. T., et al. (2006). Children’s Yale-Brown obsessive compulsive scale modified for pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 1114–1123. doi: 10.1097/01.chi.0000220854.79144.e7. PubMedCrossRef

Slosson, R. L. (1983). Slosson intelligence test. East Aurora, NY: Slosson Educational Publications.

Stigler, K. A., Desomond, L. A., Posey, D. J., Wiegand, R. E., & McDougle, C. J. (2004). A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 14, 49–56. doi: 10.1089/104454604773840481. PubMedCrossRef

Thompson, R. (1994). Emotion regulation: A theme in search of definition. Monographs of the Society for Research in Child Development, 59(2–3, Serial No. 240), 25–52.

Van Hecke, A. V., Mundy, P., Acra, C. F., Block, J. J., Delgado, C. E. F., Parlade, M. V., et al. (2007). Infant joint attention, temperament, and social competence in preschool children. Child Development, 78, 53–69. doi: 10.1111/j.1467-8624.2007.00985.x. CrossRef

Wetherby, A. M., Prizant, B. M., & Schuler, A. L. (2000). Understanding the nature of communication and language impairments. In A. M. Wetherby & B. M. Prizant (Eds.), Autism spectrum disorders: A transactional developmental perspective (pp. 109–141). Baltimore, MD: Paul H. Brookes.

Yoder, P., & Stone, W. (2006). Randomized comparison of two communication interventions for preschoolers with autism spectrum disorders. Journal of Consulting and Clinical Psychology, 74, 426–435. doi: 10.1037/0022-006X.74.3.426. PubMedCrossRef

Titel: Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity
Auteurs: Laudan B. Jahromi
Connie L. Kasari
James T. McCracken
Lisa S-Y. Lee
Michael G. Aman
Christopher J. McDougle
Lawrence Scahill
Elaine Tierney
L. Eugene Arnold
Benedetto Vitiello
Louise Ritz
Andrea Witwer
Erin Kustan
Jaswinder Ghuman
David J. Posey
Publicatiedatum: 01-03-2009
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 3/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-008-0636-9

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