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Gepubliceerd in: Journal of Autism and Developmental Disorders 12/2015

24-07-2014 | Original Paper

Positive Affect Processing and Joint Attention in Infants at High Risk for Autism: An Exploratory Study

Auteurs: Alexandra P. Key, Lisa V. Ibanez, Heather A. Henderson, Zachary Warren, Daniel S. Messinger, Wendy L. Stone

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2015

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Abstract

Few behavioral indices of risk for autism spectrum disorders (ASD) are present before 12 months, and potential biomarkers remain largely unexamined. This prospective study of infant siblings of children with ASD (n = 16) and low-risk comparison infants (n = 15) examined group differences in event-related potentials (ERPs) indexing processing of facial positive affect (N290/P400, Nc) at 9 months and their relation to joint attention at 15 months. Group differences were most pronounced for subtle facial expressions, in that the low-risk group exhibited relatively longer processing (P400 latency) and greater attention resource allocation (Nc amplitude). Exploratory analyses found associations between ERP responses and later joint attention, suggesting that attention to positive affect cues may support the development of other social competencies.
Voetnoten
1
Consistency in the recruitment procedures and inclusion/exclusion criteria as well as in data acquisition procedures was ensured by joint in-person training on all study procedures for the research staff at the three sites. Standardized behavioral assessments at each site were administered by trained clinical psychologists, ensuring strict adherence to the established procedural guidelines. All EEG data were processed and analyzed by the single lab, ensuring consistency in artifact detection procedures.
 
Literatuur
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders-IV-text revision. Washington, DC: Author. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders-IV-text revision. Washington, DC: Author.
go back to reference Berument, S., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. The British Journal of Psychiatry, 175, 444–451.CrossRefPubMed Berument, S., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. The British Journal of Psychiatry, 175, 444–451.CrossRefPubMed
go back to reference Boccia, M., & Campos, J. J. (1989). Maternal emotional signals, social referencing, and infants’ reactions to strangers. New Directions for Child Development, 44, 25–49.CrossRefPubMed Boccia, M., & Campos, J. J. (1989). Maternal emotional signals, social referencing, and infants’ reactions to strangers. New Directions for Child Development, 44, 25–49.CrossRefPubMed
go back to reference Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., et al. (1994). A case–control family history study of autism. Journal of Child Psychology and Psychiatry, 35, 877–900.CrossRefPubMed Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., et al. (1994). A case–control family history study of autism. Journal of Child Psychology and Psychiatry, 35, 877–900.CrossRefPubMed
go back to reference Campos, J., & Stenberg, C. (1981). Perception, appraisal and emotion: The onset of social referencing. In M. E. Lamb & L. R. Sherrod (Eds.), Infant social cognition. Hillsdale, NJ: Erlbaum. Campos, J., & Stenberg, C. (1981). Perception, appraisal and emotion: The onset of social referencing. In M. E. Lamb & L. R. Sherrod (Eds.), Infant social cognition. Hillsdale, NJ: Erlbaum.
go back to reference Chevallier, C., Kohls, G., Troiani, V., Brodkin, E. S., & Schultz, R. T. (2012). The social motivation theory of autism. Trends in Cognitive Sciences, 16(4), 231–239.PubMedCentralCrossRefPubMed Chevallier, C., Kohls, G., Troiani, V., Brodkin, E. S., & Schultz, R. T. (2012). The social motivation theory of autism. Trends in Cognitive Sciences, 16(4), 231–239.PubMedCentralCrossRefPubMed
go back to reference Csibra, G., Kushnerenko, E., & Grossmann, T. (2008). Electrophysiological methods in studying infant cognitive development. In C.A. Nelson & M. Luciana (Eds.), Handbook of Developmental Cognitive Neuroscience (2nd ed., pp. 247–262). MIT Press. Csibra, G., Kushnerenko, E., & Grossmann, T. (2008). Electrophysiological methods in studying infant cognitive development. In C.A. Nelson & M. Luciana (Eds.), Handbook of Developmental Cognitive Neuroscience (2nd ed., pp. 247–262). MIT Press.
go back to reference Dawson, G., Toth, K., Abbott, R., Osterling, J., Munson, J., Estes, A., et al. (2004). Early social attention impairments in autism: Social orienting, joint attention, and attention to distress. Developmental Psychology, 40, 271–283.CrossRefPubMed Dawson, G., Toth, K., Abbott, R., Osterling, J., Munson, J., Estes, A., et al. (2004). Early social attention impairments in autism: Social orienting, joint attention, and attention to distress. Developmental Psychology, 40, 271–283.CrossRefPubMed
go back to reference Dawson, G., Webb, S. J., Wijsman, E., Schellenberg, G., Estes, A., Munson, J., et al. (2005). Neurocognitive and electrophysiological evidence of altered face processing in parents of children with autism: implications for a model of abnormal development of social brain circuitry in autism. Development and Psychopathology, 17(3), 679–697. doi:10.1017/S0954579405050327.CrossRefPubMed Dawson, G., Webb, S. J., Wijsman, E., Schellenberg, G., Estes, A., Munson, J., et al. (2005). Neurocognitive and electrophysiological evidence of altered face processing in parents of children with autism: implications for a model of abnormal development of social brain circuitry in autism. Development and Psychopathology, 17(3), 679–697. doi:10.​1017/​S095457940505032​7.CrossRefPubMed
go back to reference de Haan, M., Belsky, J., Reid, V., Volein, A., & Johnson, M. H. (2004). Maternal personality and infants’ neural and visual responsivity to facial expressions of emotion. Journal of Child Psychology and Psychiatry, 45, 1209–1218.CrossRefPubMed de Haan, M., Belsky, J., Reid, V., Volein, A., & Johnson, M. H. (2004). Maternal personality and infants’ neural and visual responsivity to facial expressions of emotion. Journal of Child Psychology and Psychiatry, 45, 1209–1218.CrossRefPubMed
go back to reference de Haan, M., Johnson, M. H., & Halit, H. (2003). Development of face-sensitive event-related potentials during infancy: A review. International Journal of Psychophysiology, 51(1), 45–58.CrossRefPubMed de Haan, M., Johnson, M. H., & Halit, H. (2003). Development of face-sensitive event-related potentials during infancy: A review. International Journal of Psychophysiology, 51(1), 45–58.CrossRefPubMed
go back to reference de Haan, M., & Nelson, C. A. (1997). Recognition of the mother’s face by six-month-old infants: A neurobehavioral study. Child Development, 68(2), 187–210.CrossRefPubMed de Haan, M., & Nelson, C. A. (1997). Recognition of the mother’s face by six-month-old infants: A neurobehavioral study. Child Development, 68(2), 187–210.CrossRefPubMed
go back to reference de Haan, M., & Nelson, C. A. (1999). Brain activity differentiates face and object processing in 6-month-old infants. Developmental Psychology, 35(4), 1113–1121.CrossRefPubMed de Haan, M., & Nelson, C. A. (1999). Brain activity differentiates face and object processing in 6-month-old infants. Developmental Psychology, 35(4), 1113–1121.CrossRefPubMed
go back to reference Dereu, M., Roeyers, H., & Raymaekers, R. (2012). Exploring individual trajectories of social communicative development in toddlers at risk for autism spectrum disorders. Research in Autism Spectrum Disorders, 6(3), 1038–1052.CrossRef Dereu, M., Roeyers, H., & Raymaekers, R. (2012). Exploring individual trajectories of social communicative development in toddlers at risk for autism spectrum disorders. Research in Autism Spectrum Disorders, 6(3), 1038–1052.CrossRef
go back to reference Eimer, M., & Holmes, A. (2002). An ERP study on the time course of emotional face processing. NeuroReport, 13(4), 427–431.CrossRefPubMed Eimer, M., & Holmes, A. (2002). An ERP study on the time course of emotional face processing. NeuroReport, 13(4), 427–431.CrossRefPubMed
go back to reference Georgiades, S., Szatmari, P., Zwaigenbaum, L., Bryson, S., Brian, J., Roberts, W., Smith, I., et al. (2012). A prospective study of autistic-like traits in unaffected siblings of probands with autism spectrum disorder. Archives of General Psychiatry, E1–E7. doi:10.1001/2013.jamapsychiatry.1. Georgiades, S., Szatmari, P., Zwaigenbaum, L., Bryson, S., Brian, J., Roberts, W., Smith, I., et al. (2012). A prospective study of autistic-like traits in unaffected siblings of probands with autism spectrum disorder. Archives of General Psychiatry, E1–E7. doi:10.​1001/​2013.​jamapsychiatry.​1.
go back to reference Halit, H., de Haan, M., & Johnson, M. H. (2003). Cortical specialization for face processing: Face-sensitive event-related potential components in 3- and 12-month-old infants. Neuroimage, 19(3), 1180–1193.CrossRefPubMed Halit, H., de Haan, M., & Johnson, M. H. (2003). Cortical specialization for face processing: Face-sensitive event-related potential components in 3- and 12-month-old infants. Neuroimage, 19(3), 1180–1193.CrossRefPubMed
go back to reference Hornik, R., & Gunnar, M. R. (1988). A descriptive analysis of infant social referencing. Child Development, 59, 626–634.CrossRefPubMed Hornik, R., & Gunnar, M. R. (1988). A descriptive analysis of infant social referencing. Child Development, 59, 626–634.CrossRefPubMed
go back to reference Ibanez, L. V., Grantz, C. J., & Messinger, D. S. (2013). The development of referential communication and autism symptomatology in high-risk infants. Infancy, 18(5), 687–707. Ibanez, L. V., Grantz, C. J., & Messinger, D. S. (2013). The development of referential communication and autism symptomatology in high-risk infants. Infancy, 18(5), 687–707.
go back to reference Key, A., & Stone, W. (2012a). Processing of novel and familiar faces in infants at average and high risk for autism. Developmental Cognitive Neuroscience, 2, 244–255.CrossRefPubMed Key, A., & Stone, W. (2012a). Processing of novel and familiar faces in infants at average and high risk for autism. Developmental Cognitive Neuroscience, 2, 244–255.CrossRefPubMed
go back to reference Key, A., & Stone, W. (2012b). Same but different: Nine-month-old infants at low and high risk for autism look at the same facial features but process them using different brain mechanisms. Autism Research, 5, 253–266.PubMedCentralCrossRefPubMed Key, A., & Stone, W. (2012b). Same but different: Nine-month-old infants at low and high risk for autism look at the same facial features but process them using different brain mechanisms. Autism Research, 5, 253–266.PubMedCentralCrossRefPubMed
go back to reference Key, A., Stone, W., & Williams, S. (2009). What do infants see in faces? ERP evidence of different roles of eyes and mouth for face perception in 9-month-old infants. Infant and Child Development, 18, 149–162.PubMedCentralCrossRefPubMed Key, A., Stone, W., & Williams, S. (2009). What do infants see in faces? ERP evidence of different roles of eyes and mouth for face perception in 9-month-old infants. Infant and Child Development, 18, 149–162.PubMedCentralCrossRefPubMed
go back to reference Leppänen, J., Moulson, M., Vogel-Farley, V., & Nelson, C. (2007). An ERP study of emotional face processing in the adult and infant brain. Child Development, 78(1), 232–245.PubMedCentralCrossRefPubMed Leppänen, J., Moulson, M., Vogel-Farley, V., & Nelson, C. (2007). An ERP study of emotional face processing in the adult and infant brain. Child Development, 78(1), 232–245.PubMedCentralCrossRefPubMed
go back to reference Lord, C., Risi, S., Lambrecht, L., Cook, E. H, Jr, Leventhal, B. L., DiLavore, P. C., et al. (2000). The Autism Diagnostic Observation Schedule-Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.CrossRefPubMed Lord, C., Risi, S., Lambrecht, L., Cook, E. H, Jr, Leventhal, B. L., DiLavore, P. C., et al. (2000). The Autism Diagnostic Observation Schedule-Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223.CrossRefPubMed
go back to reference McCleery, J., Akshoomoff, N., Dobkins, K., & Carver, L. (2009). Atypical face versus object processing and hemispheric asymmetries in 10-month-old infants at risk for autism. Biological Psychiatry, 66, 950–957.PubMedCentralCrossRefPubMed McCleery, J., Akshoomoff, N., Dobkins, K., & Carver, L. (2009). Atypical face versus object processing and hemispheric asymmetries in 10-month-old infants at risk for autism. Biological Psychiatry, 66, 950–957.PubMedCentralCrossRefPubMed
go back to reference Messinger, D., Young, G. S., Ozonoff, S., Dobkins, K., Carter, A., Zwaigenbaum, L., et al. (2013). Beyond ASD: A Baby Siblings Research Consortium study of high-risk siblings at three years of age. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 300–308. Messinger, D., Young, G. S., Ozonoff, S., Dobkins, K., Carter, A., Zwaigenbaum, L., et al. (2013). Beyond ASD: A Baby Siblings Research Consortium study of high-risk siblings at three years of age. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 300–308.
go back to reference Mundy, P., Fox, N., & Card, J. (2003). EEG coherence, joint attention and language development in the second year. Developmental Science, 6, 48–54.CrossRef Mundy, P., Fox, N., & Card, J. (2003). EEG coherence, joint attention and language development in the second year. Developmental Science, 6, 48–54.CrossRef
go back to reference Mundy, P. C., Henderson, H. A., Inge, A. P., & Coman, D. C. (2007). The modifier model of autism and social development in higher functioning children with autism. Research and Practice for Persons with Severe Disabilities, 32, 124–139.PubMedCentralCrossRefPubMed Mundy, P. C., Henderson, H. A., Inge, A. P., & Coman, D. C. (2007). The modifier model of autism and social development in higher functioning children with autism. Research and Practice for Persons with Severe Disabilities, 32, 124–139.PubMedCentralCrossRefPubMed
go back to reference Mundy, P., & Sigman, M. (2006). Joint attention, social competence, and developmental psychopathology. In Mundy, P., & Sigman, M. (Eds.), Developmental psychopathology, Vol 1: Theory and method (2nd ed., pp. 293–332). Hoboken, NJ, US: Wiley. Mundy, P., & Sigman, M. (2006). Joint attention, social competence, and developmental psychopathology. In Mundy, P., & Sigman, M. (Eds.), Developmental psychopathology, Vol 1: Theory and method (2nd ed., pp. 293–332). Hoboken, NJ, US: Wiley.
go back to reference Nelson, C. A., & de Haan, M. (1996). Neural correlates of infants’ visual responsiveness to facial expressions of emotion. Developmental Psychobiology, 29, 577–595.CrossRefPubMed Nelson, C. A., & de Haan, M. (1996). Neural correlates of infants’ visual responsiveness to facial expressions of emotion. Developmental Psychobiology, 29, 577–595.CrossRefPubMed
go back to reference Osterling, J., & Dawson, G. (1994). Early recognition of children with autism: A study of first birthday home videotapes. Journal of Autism and Developmental Disorders, 24(3), 247–257.CrossRefPubMed Osterling, J., & Dawson, G. (1994). Early recognition of children with autism: A study of first birthday home videotapes. Journal of Autism and Developmental Disorders, 24(3), 247–257.CrossRefPubMed
go back to reference Ozonoff, S., Young, G. S., Carter, A., Messinger, D., Yirmiya, N., Zwaigenbaum, L., et al. (2011). Recurrence risk for autism spectrum disorders: A baby siblings research consortium study. Pediatrics, 128(3), 488–495. Ozonoff, S., Young, G. S., Carter, A., Messinger, D., Yirmiya, N., Zwaigenbaum, L., et al. (2011). Recurrence risk for autism spectrum disorders: A baby siblings research consortium study. Pediatrics, 128(3), 488–495.
go back to reference Pelphrey, K. A., Shultz, S., Hudac, C. M., & Vander Wyk, B. C. (2011). Constraining heterogeneity: The social brain and its development in autism spectrum disorder. Journal of Child Psychology and Psychiatry and Allied Disciplines, 52(6), 631–644. doi:10.1111/j.1469-7610.2010.02349.x.CrossRef Pelphrey, K. A., Shultz, S., Hudac, C. M., & Vander Wyk, B. C. (2011). Constraining heterogeneity: The social brain and its development in autism spectrum disorder. Journal of Child Psychology and Psychiatry and Allied Disciplines, 52(6), 631–644. doi:10.​1111/​j.​1469-7610.​2010.​02349.​x.CrossRef
go back to reference Presmanes, A. G., Walden, T. A., Stone, W. L., & Yoder, P. J. (2007). Effects of different attentional cues on responding to joint attention in younger siblings of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(1), 133–144.CrossRefPubMed Presmanes, A. G., Walden, T. A., Stone, W. L., & Yoder, P. J. (2007). Effects of different attentional cues on responding to joint attention in younger siblings of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(1), 133–144.CrossRefPubMed
go back to reference Reynolds, G., & Richards, J. (2005). Familiarization, attention, and recognition memory in infancy: An event-related potential and cortical source localization study. Developmental Psychology, 41(4), 598–615.PubMedCentralCrossRefPubMed Reynolds, G., & Richards, J. (2005). Familiarization, attention, and recognition memory in infancy: An event-related potential and cortical source localization study. Developmental Psychology, 41(4), 598–615.PubMedCentralCrossRefPubMed
go back to reference Rosen, W. D., Adamson, L. B., & Bakeman, R. (1992). An experimental investigation of infant social referencing: Mother’s messages and gender differences. Developmental Psychology, 28, 1172–1178.CrossRef Rosen, W. D., Adamson, L. B., & Bakeman, R. (1992). An experimental investigation of infant social referencing: Mother’s messages and gender differences. Developmental Psychology, 28, 1172–1178.CrossRef
go back to reference Rozga, A., Hutman, T., Young, G. S., Rogers, S. J., Ozonoff, S., Dapretto, M., et al. (2011). Behavioral profiles of affected and unaffected siblings of children with autism: Contribution of measures of mother–infant interaction and nonverbal communication. Journal of Autism and Developmental Disorders, 41(3), 287–301.PubMedCentralCrossRefPubMed Rozga, A., Hutman, T., Young, G. S., Rogers, S. J., Ozonoff, S., Dapretto, M., et al. (2011). Behavioral profiles of affected and unaffected siblings of children with autism: Contribution of measures of mother–infant interaction and nonverbal communication. Journal of Autism and Developmental Disorders, 41(3), 287–301.PubMedCentralCrossRefPubMed
go back to reference Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised (ADI–R) manual. Los Angeles: Western Psychological Services. Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism diagnostic interview-revised (ADI–R) manual. Los Angeles: Western Psychological Services.
go back to reference Scott, L., & Nelson, C. (2006). Featural and configural face processing in adults and infants: A behavioral and electrophysiological investigation. Perception, 35, 1107–1128.CrossRefPubMed Scott, L., & Nelson, C. (2006). Featural and configural face processing in adults and infants: A behavioral and electrophysiological investigation. Perception, 35, 1107–1128.CrossRefPubMed
go back to reference Sepeta, L., Tsuchiya, N., Davies, M. S., Sigman, M., Bookheimer, S. Y., & Dapretto, M. (2012). Abnormal social reward processing in autism as indexed by pupillary responses to happy faces. Journal of Neurodevelopmental Disorders, 4, 17.PubMedCentralCrossRefPubMed Sepeta, L., Tsuchiya, N., Davies, M. S., Sigman, M., Bookheimer, S. Y., & Dapretto, M. (2012). Abnormal social reward processing in autism as indexed by pupillary responses to happy faces. Journal of Neurodevelopmental Disorders, 4, 17.PubMedCentralCrossRefPubMed
go back to reference Stone, W. L., McMahon, C. R., Yoder, P. J., & Walden, T. A. (2007). Early social communicative and cognitive development of younger sibling of children with autism spectrum disorders. Archive of Pediatrics and Adolescent Medicine, 161, 384–390.CrossRef Stone, W. L., McMahon, C. R., Yoder, P. J., & Walden, T. A. (2007). Early social communicative and cognitive development of younger sibling of children with autism spectrum disorders. Archive of Pediatrics and Adolescent Medicine, 161, 384–390.CrossRef
go back to reference Tabachnick, B. G., Fidell, L. S., & Osterlind, S. J. (2001). Using multivariate statistics. Allyn and Bacon. Tabachnick, B. G., Fidell, L. S., & Osterlind, S. J. (2001). Using multivariate statistics. Allyn and Bacon.
go back to reference Thomas, D., Grice, J., Najm-Briscoe, R., & Miller, J. (2004). The influence of unequal numbers of trials on comparisons of average event-related potentials. Developmental Neuropsychology, 26, 753–774.CrossRefPubMed Thomas, D., Grice, J., Najm-Briscoe, R., & Miller, J. (2004). The influence of unequal numbers of trials on comparisons of average event-related potentials. Developmental Neuropsychology, 26, 753–774.CrossRefPubMed
go back to reference Tomasello, M. (1992). The social bases of language acquisition. Social Development, 1, 67–87.CrossRef Tomasello, M. (1992). The social bases of language acquisition. Social Development, 1, 67–87.CrossRef
go back to reference Trevarthen, C., & Hubley, P. (1978). Secondary intersubjectivity: confidence, confiding and acts of meaning in the first year. In A. Lock (Ed.), Action, gesture and symbol: The emergence of language. New York and London: Academic Press. Trevarthen, C., & Hubley, P. (1978). Secondary intersubjectivity: confidence, confiding and acts of meaning in the first year. In A. Lock (Ed.), Action, gesture and symbol: The emergence of language. New York and London: Academic Press.
go back to reference Wetherby, A. M., Woods, J., Allen, L., Cleary, J., Dickinson, H., & Lord, C. (2004). Early indicators of autism spectrum disorders in the second year of life. Journal of Autism and Development Disorders, 34(5), 473–493.CrossRef Wetherby, A. M., Woods, J., Allen, L., Cleary, J., Dickinson, H., & Lord, C. (2004). Early indicators of autism spectrum disorders in the second year of life. Journal of Autism and Development Disorders, 34(5), 473–493.CrossRef
go back to reference Wong, N., Beidel, D. C., Sarver, D. E., & Sims, V. (2012). Facial emotion recognition in children with high functioning autism and children with social phobia. Child Psychiatry and Human Development, 43(5), 775–794. doi:10.1007/s10578-012-0296-z.CrossRefPubMed Wong, N., Beidel, D. C., Sarver, D. E., & Sims, V. (2012). Facial emotion recognition in children with high functioning autism and children with social phobia. Child Psychiatry and Human Development, 43(5), 775–794. doi:10.​1007/​s10578-012-0296-z.CrossRefPubMed
go back to reference Yirmiya, N., Gamliel, I., Pilowsky, T., Feldman, R., Baron Cohen, S., & Sigman, M. (2006). The development of siblings of children with autism at 4 and 14 months: Social engagement, communication, and cognition. Journal of Child Psychology and Psychiatry, 47(5), 511–523.CrossRefPubMed Yirmiya, N., Gamliel, I., Pilowsky, T., Feldman, R., Baron Cohen, S., & Sigman, M. (2006). The development of siblings of children with autism at 4 and 14 months: Social engagement, communication, and cognition. Journal of Child Psychology and Psychiatry, 47(5), 511–523.CrossRefPubMed
go back to reference Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005). Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience, 23(2–3), 143–152.CrossRefPubMed Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005). Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience, 23(2–3), 143–152.CrossRefPubMed
Metagegevens
Titel
Positive Affect Processing and Joint Attention in Infants at High Risk for Autism: An Exploratory Study
Auteurs
Alexandra P. Key
Lisa V. Ibanez
Heather A. Henderson
Zachary Warren
Daniel S. Messinger
Wendy L. Stone
Publicatiedatum
24-07-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 12/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2191-x

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