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26-05-2020 | Original Article | Uitgave 5/2020 Open Access

Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy

Tijdschrift:: Cognitive Therapy and Research > Uitgave 5/2020

Auteurs:: Anita Eskildsen, Nina Reinholt, Suzanne van Bronswijk, René B. K. Brund, Anne B. Christensen, Morten Hvenegaard, Mikkel Arendt, Anja Alrø, Stig Poulsen, Nicole K. Rosenberg, Marcus J. H. Huibers, Sidse Arnfred

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Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (https://doi.org/10.1007/s10608-020-10116-1) contains supplementary material, which is available to authorized users.

Nina Reinholt, Suzanne van Bronswijk, René B. K. Brund have equally contributed.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Background

Only about half of all patients with anxiety disorders or major depression respond to cognitive behaviour therapy (CBT), even though this is an evidence-based treatment. Personalized treatment offers an approach to increase the number of patients who respond to therapy. The aim of this study was to examine predictors and moderators of (differential) treatment outcomes in transdiagnostic versus diagnosis-specific group CBT.

Methods

A sample of 291 patients from three different mental health clinics in Denmark was randomized to either transdiagnostic or diagnosis-specific group CBT. The study outcome was the regression slope of the individual patient's repeated scores on the WHO-5 Well-being Index. Pre-treatment variables were identified as moderators or predictors through a two-step variable selection approach.

Results

While the two-step approach failed to identify any moderators, four predictors were found: level of positive affect, duration of disorder, the detachment personality trait, and the coping strategy of cognitive reappraisal. A prognostic index was constructed, but did not seem to be robust across treatment sites.

Conclusions

Our findings give insufficient evidence to support a recommendation of either transdiagnostic or diagnosis-specific CBT for a given patient or to predict the response to the applied group therapies.

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Titel: Personalized Psychotherapy for Outpatients with Major Depression and Anxiety Disorders: Transdiagnostic Versus Diagnosis-Specific Group Cognitive Behavioural Therapy
Auteurs:: Anita Eskildsen
Nina Reinholt
Suzanne van Bronswijk
René B. K. Brund
Anne B. Christensen
Morten Hvenegaard
Mikkel Arendt
Anja Alrø
Stig Poulsen
Nicole K. Rosenberg
Marcus J. H. Huibers
Sidse Arnfred
Publicatiedatum: 26-05-2020
DOI: https://doi.org/10.1007/s10608-020-10116-1
Uitgeverij: Springer US
Tijdschrift: Cognitive Therapy and Research
Uitgave 5/2020
Print ISSN: 0147-5916
Elektronisch ISSN: 1573-2819

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